α-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway

Neuroscience Letters

Volumn 312, Issue 3, 2001, Pages 125-128

  Zhang, Lei ^a   Xing, Gou qaing ^a   Barker, Jeffery L ^b   Chang, Yoong ^b   Maric, Dragan ^b   Ma, Wu ^c   Li, Bing sheng ^b   Rubinow, David R ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c NAVAL RESEARCH LABORATORY   (United States)

Author keywords

Alzheimer's disease; Antioxidants; Apoptosis; Cell death; Lipoic acid; Neuron

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMYLOID BETA PROTEIN; ANTIOXIDANT; FLUORESCENT DYE; HYDROGEN PEROXIDE; PROPIDIUM IODIDE; PROTEIN; PROTEIN KINASE; PROTEIN KINASE B; PROTIEN AKT; THIOCTIC ACID; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CORTEX; CELL DEATH; CELL LEVEL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; FETUS; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANTIOXIDANTS; BIOLOGICAL ASSAY; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; COLORING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FETUS; HYDROGEN PEROXIDE; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; THIOCTIC ACID;

EID: 0035955513     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)02205-4     Document Type: Article

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