Regional membrane phospholipid alterations in Alzheimer's disease

Neurochemical Research

Volumn 23, Issue 1, 1998, Pages 81-88

  Prasad, M Renuka ^a,c   Lovell, Mark A ^a,b   Yatin, Mustafa ^a   Dhillon, Harbhajan ^a   Markesbery, William R ^a,b  

^a Department of Surgery ^*  (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Free fatty acids; Phosphatid ylinositol; Phosphatidylcholine; Phosphatidylethanolamine; Phospholipids

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; FATTY ACID; MEMBRANE PHOSPHOLIPID; OLEIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; STEARIC ACID;

AGED; ALZHEIMER DISEASE; ARTICLE; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIPID ANALYSIS; MALE; OXIDATIVE STRESS; PARIETAL LOBE; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; TEMPORAL LOBE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ARACHIDONIC ACID; BRAIN; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS; FATTY ACIDS, NONESTERIFIED; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MEMBRANE LIPIDS; OLEIC ACID; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPIDS; STEARIC ACIDS;

EID: 0031942410     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022457605436     Document Type: Article

References (49)

1. Hazel, J. R., and Williams, E. E. 1990. The role of alterations in membrane lipid composition in enabling physiological adaptation of organisms to their physical environment. Prog. Lipid. Res. 29:167-227.
2. Dhillon, H. S., Donaldson, D., Dempsey, R. J., and Prasad, M. R. 1993. Regional levels of free fatty acids and Evans blue extravasation after experimental brain injury. J. Neurotrauma. 11:405-415.
3. Suzuki, K. 1981. Chemistry and metabolism of brain lipids. Pages 355-370, in Siegel, G. J., Albers, R. W., Agranoff, B. W., and Katzman, R. (eds.), Basic neurochemistry, 3rd ed., Little, Brown, Boston.
4. Mason, R. P., Estermyer, J. D., Kelly, J. F., and Mason, P. E. 1996. Alzheimer's disease amyloid β-peptide 25-35 is localized in the membrane hydrocarbon core: X-ray diffraction analysis. Biochem. Biophys. Res. Commn. 222:78-82.
5. Barany, M., Chang, Y. C., Arus, C., Rustan, T., and Frey, W. H. Jr. 1985. Increased glycerol-3-phosphorylcholine in post-mortem Alzheimer's brain [letter]. Lancet. 1:517.
6. Blusztajn, J. K., Gonzalez-Coviella, I., Logue, M., Growdon, J. H., and Wurtman, R. J. 1990. Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients. Brain. Res. 536:240-244.
7. 31P NMR spectroscopy detects altered phospholipid metabolism in Alzheimer's disease. Can. J. Neurol. Sci. 13:535-539.
8. Nitsch, R. M., Blusztajn, J. K., Pittas, A. G., Slack, B. E., Growdon, J. H., and Wurtman, R. J. 1992. Evidence for a membrane defect in Alzheimer's disease brain. Proc. Natl. Acad. Sci. USA. 89:1671-1675.
9. 31P nuclear magnetic resonance study of the brain in Alzheimer's disease. J. Neuropathol. Exp. Neurol. 47: 235-248.
10. Pettegrew, J. W., Panchalingam, K., Moossy, J., Martinez, J., Rao, G., and Boller, F. 1988. Correlation of phosphorus-31 magnetic resonance spectroscopy and morphologic findings in Alzheimer's disease. Arch. Neurol. 45:1093-1096.
11. 31P magnetic resonance spectroscopy in Alzheimer's disease and Pick's disease. Neurobiol. Aging. 14:85-92.
12. Svennerholm, L., and Gottfries, C. G. 1994. Membrane lipids, selectively diminished in Alzheimer brains. suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II). J. Neurochem. 62:1039-1047.
13. Abe, K., Kogure, K., Yamamoto, H., Imazawa, M., and Miyamoto, K. 1987. Mechanism of arachidonic acid liberation during ischemia in gerbil cerebral cortex. J. Neurochem. 48:503-509.
14. Bazan, N. G., Jr. 1970. Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain. Biochim. Biophys. Acta. 218:1-10.
15. Dhillon, H. S., Carbary, T., Dose, J., Dempsey, R. J., and Prasad, M. R. 1995. Activation of phosphatidylinositol bisphosphate signal transduction pathway after experimental brain injury: A lipid study. Brain Res. 698:100-106.
16. 2 and C activation during ischemia. J. Neurochem. 61:1677-1684.
17. Lovell, M. A., Ehmann, W. D., Butler, S. M., and Markesbery, W. R. 1995. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology. 45:1594-1601.
18. Hall, E. D., McCall, J. M., and Means, E. D. 1994. Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Adv. Pharmacol. 28:221-268.
19. Halliwell, B., and Gutteridge, J. M. C. 1989. Free radicals in biology and medicine, 2nd ed., Claredon Press, Oxford.
20. Halliwell, B. 1992. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1609-1623.
21. Rice-Evans, C., and Burdon, R. 1993. Free radical-lipid interactions and their pathological consequences. Prog. Lipid Res. 32: 71-110.
22. Behl, C., Davis, J. B., Lesley, R., and Schubert, D. 1994. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 77:817-827.
23. Carney, J. M., Starke-Reed, P. E., Oliver, C. N., Landum, R. M., Cheng, M. S., Wu, J. F., and Floyd, R. A. 1991. Reversal of agerelated increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone. Proc. Natl. Acad. Sci. USA. 88:3633-3636.
24. Hensley, K., Carney, J. M., Mattson, M. P., Aksenova, M., Harris, M., Wu, J. F., Floyd, R. A., and Butterfield, D. A. 1994. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 91:3270-3274.
25. Van, S. D., Chen, X., Schmidt, A. M., Brett, J., Godman, G., Zou, Y. S., Scott, C. W., Caputo, C., Frappier, T., Smith, M. A., Perry, G., Yen, S. H., and Stern, D. 1994. Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress. Proc. Natl. Acad. Sci. USA. 91:7787-7791.
26. Blass, J. P., and Gibson, G. E. 1991. The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease. Rev. Neurol. (Paris). 147:513-525.
27. Ehmann, W. D., Markesbery, W. R., Alauddin, M., and Hossain, T. I. M. 1986. Brain trace elements in Alzheimer's disease. Neurotoxicology. 7:197-206.
28. Thompson, C. M., Markesbery, W. R., Ehmann, W. D., Mao, Y.-X., and Vance, D. E. 1988. Regional brain trace-element studies in Alzheimer's disease. Neurotoxicology. 9:1-8.
29. McKhann, G., Drachman, D., Folstein, M., Price, D., and Stadlan, E. M. 1984. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRA work group under the auspices of the Department of Health Services Task Force on Alzheimer's disease. Neurology. 34:939-944.
30. Khachaturian, Z. S. 1985. Diagnosis of Alzheimer's disease (Conference report). Arch. Neurol. 42:1097-1105.
31. Mirra, S. S., Hart, M. N., and Terry, R. D. 1993. Making the diagnosis of Alzheimer's disease. A primer for practicing pathologists. Arch. Pathol. Lab. Med. 117:132-144.
32. Wells, K., Farooqui, A. A., Liss, L., and Horrocks, L. A. 1995. Neural membrane phospholipids in Alzheimer's disease. Neurochem. Res. 20:1329-1333.
33. Crino, P. B., Ullman, M. D., Vogt, B. A., Bird, E. D., and Volicer, L. 1989. Brain gangliosides in dementia of the Alzheimer type. Arch. Neurol. 46:398-401.
34. Kracun, I., Kalanj, S., Cosovic, C., and Talan-Hranilovic, J. 1990. Brain gangliosides in Alzheimer's disease. J. Hirnforsch. 31: 789-793.
35. Ikeda, M., Yoshida, S., Busto, R., Santiso, M., and Ginsberg, M. D. 1986. Polyphosphoinositides as a probable source of brain free fatty acids accumulated at the onset of ischemia. J. Neurochem. 47:123-132.
36. Prasad, M. R., Dhillon, H. S., Carbary, T., Dempsey, R. J., and Scheff, S. W. 1994. Enhanced phosphodiestric breakdown of phosphatidylinositol bisphosphate after experimental brain injury. J. Neurochem. 63:773-776.
37. 2(s); comparison of arachidonoyl-selective and -nonselective enzymes. FASEB J. 7:339-348.
38. Hensley, K., Hall, N., Subramaniam, R., Cole, P., Harris, M., Aksenov, M., Aksenova, M., Gabbita, S. P., Wu, J. F., Carney, J. M., Lovell, M., Markesbery, W. R., and Butterfield, D. A. 1995. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. J. Neurochem. 65:2146-2156.
39. Mark, R. J., Blanc, E. M., and Mattson, M. P. 1996. Amyloid β-peptide and oxidative cellular injury in Alzheimer's disease. Mol. Neuro. 12:211-224.
40. Ginsberg, L., Rafique, S., Xuereb, J. H., Rapoport, S. I., and Gershfeld, N. L. 1995. Disease and anatomic specificity of ethanolamine plasmalogen deficiency in Alzheimer's disease brain. Brain Res. 698:223-226.
41. Goodman, Y., and Mattson, M. P. 1994. Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury. Exp. Neurol. 128:1-12.
42. Harris, M. E., Hensley, K., Butterfield, D. A., Leedle, R. E., and Camey, J. M. 1995. Direct evidence of oxidative injury produced by the Alzheimer's β-amyloid peptide (1-40) in cultured hippocampal neurons. Exp. Neurol. 131:193-202.
43. Butterfield, D. A., Hensley, K., Harris, M., Mattson, M., and Carney, J. 1994. β-amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. Biochem. Biophys. Res. Commn. 200:710-715.
44. Hensley, K., Aksenova, M., Carney, J. M., Harris, M., and Butterfield, D. A. 1995. Amyloid β-peptide spin trapping. I. Peptide enzyme toxicity is related to free radical spin trap reactivity. Neuroreport. 6:489-492.
45. Hensley, K., Aksenova, M., Carney, J. M., Harris, M., and Butterfield, D. A. 1995. Amyloid β-peptide spin trapping. II. Evidence for decomposition of the PBN spin adduct. Neuroreport. 6:493-496.
46. Behl, C., Davis, J., Cole, G. M., and Schubert, D. 1992. Vitamin E protects nerve cells from amyloid β protein toxicity. Biochem. Biophys. Res. Commun. 186:944-950.
47. Dyrks, T., Dyrks, E., Hartmann, T., Masters, C., and Beyreuther, K. 1992. Amyloidogenicity of β A4 and β A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation. J. Biol. Chem. 267:18210-18217.
48. Balazs, L., and Leon, M. 1994. Evidence of an oxidative challenge in the Alzheimer's brain. Neurochem. Res. 19:1131-1137.
49. Volicer, L., and Crino, P. B. 1990. Involvement of free radicals in dementia of the Alzheimer type: a hypothesis. Neurobiol. Aging. 11:567-571.