Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-14C]quercetin-4′-glucoside

Journal of Agricultural and Food Chemistry

Volumn 50, Issue 23, 2002, Pages 6902-6909

  Mullen, William ^a   Graf, Brigitte A ^a   Caldwell, Stuart T ^b   Hartley, Richard C ^b   Duthie, Garry G ^c   Edwards, Christine A ^b   Lean, Michael E J ^b   Crozier, Alan ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

2 14C Quercetin 4 glucoside; Glucuronides; Methylated metabolites; Rat tissues; Sulfated derivatives; Tandem mass spectrometry

Indexed keywords

CARBON; CARBON 14; DIAGNOSTIC AGENT; DRUG DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOL; FLAVONOLS; QUERCETIN; QUERCETIN 4' GLUCOSIDE; QUERCETIN DERIVATIVE; SPIRAEOSIDE; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL CELL; ARTICLE; BLOOD; CHEMISTRY; CONTROLLED STUDY; DIETARY INTAKE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG TRANSPORT; DRUG URINE LEVEL; GASTROINTESTINAL TRACT EXAMINATION; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE; KIDNEY; LIVER; MALE; MASS SPECTROMETRY; METHYLATION; NONHUMAN; RADIOACTIVITY; RAT; SULFATION AND DESULFURIZATION; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

ANIMALS; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVONOIDS; FLAVONOLS; INTESTINES; KIDNEY; LIVER; MALE; MASS SPECTROMETRY; QUERCETIN; RATS; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0037032253     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf020598p     Document Type: Article

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