Mechanism of human SIRT1 activation by resveratrol

Journal of Biological Chemistry

Volumn 280, Issue 17, 2005, Pages 17187-17195

  Borra, Margie T ^a   Smith, Brian C ^a   Denu, John M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; ENZYMES; FATTY ACIDS; GENES; POLYPEPTIDES; YEAST;

CELL CYCLE REGULATION; LIFE SPAN EXTENSION; PROTEIN DEACETYLASE; RESVERATROL;

ALCOHOLS;

ACYLTRANSFERASE; COUMARIN ANTICOAGULANT; NICOTINAMIDE ADENINE DINUCLEOTIDE; POLYPHENOL; RESVERATROL; SIRTUIN; ANTIOXIDANT; COLORING AGENT; COUMARIN; COUMARIN DERIVATIVE; HISTIDINE; HISTONE DEACETYLASE; PEPTIDE; PROTEIN P53; RHODAMINE; RHODAMINE 110; SIRT1 PROTEIN, HUMAN; SIRT2 PROTEIN, HUMAN; STILBENE DERIVATIVE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL CYCLE; CONFORMATIONAL TRANSITION; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME BINDING; ENZYME SUBSTRATE; FATTY ACID METABOLISM; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; BINDING COMPETITION; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENE SILENCING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOPRECIPITATION; KINETICS; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; TIME; X RAY CRYSTALLOGRAPHY;

ANTIOXIDANTS; BINDING SITES; BINDING, COMPETITIVE; CELL CYCLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLORING AGENTS; COUMARINS; CRYSTALLOGRAPHY, X-RAY; GENE SILENCING; HISTIDINE; HISTONE DEACETYLASES; HUMANS; IMMUNOPRECIPITATION; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RHODAMINES; SIRTUINS; STILBENES; SUBSTRATE SPECIFICITY; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 20444444649     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501250200     Document Type: Article

References (67)

1. Imai, S., Armstrong, C. M., Kaeberlein, M., and Guarente, L. (2000) Nature 403, 795-800
2. Smith, J. S., Brachmann, C. B., Celic, I., Kenna, M. A., Muhammad, S., Starai, V. J., Avalos, J. L., Escalante-Semerena, J. C., Grubmeyer, C., Wolberger, C., and Boeke, J. D. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 6658-6663
3. Landry, J., Sutton, A., Tafrov, S. T., Heller, R. C., Stebbins, J., Pillus, L., and Sternglanz, R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5807-5811
4. Jackson, M. D., and Denu, J. M. (2002) J. Biol. Chem. 277, 18535-18544
5. Sauve, A. A., Celic, I., Avalos, J., Deng, H., Boeke, J. D., and Schramm, V. L. (2001) Biochemistry 40, 15456-15463
6. Tanner, K. G., Landry, J., Sternglanz, R., and Denu, J. M. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 14178-14182
7. Tanny, J. C., and Moazed, D. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 415-420
8. Frye, R. A. (1999) Biochem. Biophys. Res. Commun. 260, 273-279
9. Frye, R. A. (2000) Biochem. Biophys. Res. Commun. 273, 793-798
10. Aparicio, O. M., Billington, B. L., and Gottschling, D. E. (1991) Cell 66, 1279-1287
11. Strahl-Bolsinger, S., Hecht, A., Luo, K., and Grunstein, M. (1997) Genes Dev. 11, 83-93
12. Gottschling, D. E., Aparicio, O. M., Billington, B. L., and Zakian, V. A. (1990) Cell 63, 751-762
13. Rine, J., and Herskowitz, I. (1987) Genetics 116, 9-22
14. Shou, W., Seol, J. H., Shevchenko, A., Baskerville, C., Moazed, D., Chen, Z. W., Jang, J., Charbonneau, H., and Deshaies, R. J. (1999) Cell 97, 233-244
15. Shou, W., Sakamoto, K. M., Keener, J., Morimoto, K. W., Traverso, E. E., Azzam, R., Hoppe, G. J., Feldman, R. M., DeModena, J., Moazed, D., Charbonneau, H., Nomura, M., and Deshaies, R. J. (2001) Mol. Cell 8, 45-55
16. Bryk, M., Banerjee, M., Murphy, M., Knudsen, K. E., Garfinkel, D. J., and Curcio, M. J. (1997) Genes Dev. 11, 255-269
17. Fritze, C. E., Verschueren, K., Strich, R., and Easton Esposito, R. (1997) EMBO J. 16, 6495-6509
18. Smith, J. S., and Boeke, J. D. (1997) Genes Dev. 11, 241-254
19. Loo, S., and Rine, J. (1995) Annu. Rev. Cell Dev. Biol. 11, 519-548
20. Dryden, S. C., Nahhas, F. A., Nowak, J. E., Goustin, A. S., and Tainsky, M. A. (2003) Mol. Cell. Biol. 23, 3173-3185
21. Starai, V. J., Celic, I., Cole, R. N., Boeke, J. D., and Escalante-Semerena, J. C. (2002) Science 298, 2390-2392
22. Tissenbaum, H. A., and Guarente, L. (2001) Nature 410, 227-230
23. Kaeberlein, M., McVey, M., and Guarente, L. (1999) Genes Dev. 13, 2570-2580
24. Sinclair, D. A., and Guarente, L. (1997) Cell 91, 1033-1042
25. Luo, J., Nikolaev, A. Y., Imai, S., Chen, D., Su, F., Shiloh, A., Guarente, L., and Gu, W. (2001) Cell 107, 137-148
26. Vaziri, H., Dessain, S. K., Ng Eaton, E., Imai, S. I., Frye, R. A., Pandita, T. K., Guarente, L., and Weinberg, R. A. (2001) Cell 107, 149-159
27. Langley, E., Pearson, M., Faretta, M., Bauer, U. M., Frye, R. A., Minucci, S., Pelicci, P. G., and Kouzarides, T. (2002) EMBO J. 21, 2383-2396
28. Motta, M. C., Divecha, N., Lemieux, M., Kamel, C., Chen, D., Gu, W., Bultsma, Y., McBurney, M., and Guarente, L. (2004) Cell 116, 551-563
29. Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., Hu, L. S., Cheng, H. L., Jedrychowski, M. P., Gygi, S. P., Sinclair, D. A., Alt, F. W., and Greenberg, M. E. (2004) Science 303, 2011-2015
30. Muth, V., Nadaud, S., Grummt, I., and Voit, R. (2001) EMBO J. 20, 1353-1362
31. Yeung, F., Hoberg, J. E., Ramsey, C. S., Keller, M. D., Jones, D. R., Frye, R. A., and Mayo, M. W. (2004) EMBO J. 23, 2369-2380
32. Fulco, M., Schiltz, R. L., Iezzi, S., King, M. T., Zhao, P., Kashiwaya, Y., Hoffman, E., Veech, R. L., and Sartorelli, V. (2003) Mol. Cell 12, 51-62
33. Picard, F., Kurtev, M., Chung, N., Topark-Ngarm, A., Senawong, T., Machado De Oliveira, R., Leid, M., McBurney, M. W., and Guarente, L. (2004) Nature 429, 771-776
34. Araki, T., Sasaki, Y., and Milbrandt, J. (2004) Science 305, 1010-1013
35. Howitz, K. T., Bitterman, K. J., Cohen, H. Y., Lamming, D. W., Lavu, S., Wood, J. G., Zipkin, R. E., Chung, P., Kisielewski, A., Zhang, L. L., Scherer, B., and Sinclair, D. A. (2003) Nature 425, 191-196
36. Wood, J. G., Rogina, B., Lavu, S., Howitz, K., Helfand, S. L., Tatar, M., and Sinclair, D. (2004) Nature 430, 686-689
37. Schmidt, M. T., Smith, B. C., Jackson, M. D., and Denu, J. M. (2004) J. Biol. Chem. 279, 40122-40129
38. Sauve, A. A., and Schramm, V. L. (2003) Biochemistry 42, 9249-9256
39. Jackson, M. D., Schmidt, M. T., Oppenheimer, N. J., and Denu, J. M. (2003) J. Biol. Chem. 278, 50985-50998
40. Borra, M. T., Langer, M. R., Slama, J. T., and Denu, J. M. (2004) Biochemistry 43, 9877-9887
41. Bitterman, K. J., Anderson, R. M., Cohen, H. Y., Latorre-Esteves, M., and Sinclair, D. A. (2002) J. Biol. Chem. 277, 45099-45107
42. Lin, S. J., Ford, E., Haigis, M., Liszt, G., and Guarente, L. (2004) Genes Dev. 18, 12-16
43. Grozinger, C. M., Chao, E. D., Blackwell, H. E., Moazed, D., and Schreiber, S. L. (2001) J. Biol. Chem. 276, 38837-38843
44. Bedalov, A., Gatbonton, T., Irvine, W. P., Gottschling, D. E., and Simon, J. A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 15113-15118
45. Posakony, J., Hirao, M., Stevens, S., Simon, J. A., and Bedalov, A. (2004) J. Med. Chem. 47, 2635-2644
46. Hirao, M., Posakony, J., Nelson, M., Hruby, H., Jung, M., Simon, J. A., and Bedalov, A. (2003) J. Biol. Chem. 278, 52773-52782
47. Fang, J. G., Lu, M., Chen, Z. H., Zhu, H. H., Li, Y., Yang, L., Wu, L. M., and Liu, Z. L. (2002) Chemistry 8, 4191-4198
48. Olas, B., Wachowicz, B., Saluk-Juszczak, J., Zielinski, T., Kaca, W., and Buczynski, A. (2001) Cell Biol. Toxicol. 17, 117-125
49. Stojanovic, S., Sprinz, H., and Brede, O. (2001) Arch. Biochem. Biophys. 391, 79-89
50. Murcia, M. A., and Martinez-Tome, M. (2001) J. Food Prot. 64, 379-384
51. Burkitt, M. J., and Duncan, J. (2000) Arch. Biochem. Biophys. 381, 253-263
52. Fremont, L., Belguendouz, L., and Delpal, S. (1999) Life Sci. 64, 2511-2521
53. Pinto, M. C., Garcia-Barrado, J. A., and Macias, P. (1999) J. Agric. Food Chem. 47, 4842-4846
54. Ray, P. S., Maulik, G., Cordis, G. A., Bertelli, A. A., Bertelli, A., and Das, D. K. (1999) Free Radic. Biol. Med. 27, 160-169
55. Schultz, J. (2004) J. Natl. Cancer Inst. 96, 1497-1498
56. Aggarwal, B. B., Bhardwaj, A., Aggarwal, R. S., Seeram, N. P., Shishodia, S., and Takada, Y. (2004) Anticancer Res. 24, 2783-2840
57. Kundu, J. K., and Surh, Y. J. (2004) Mutat. Res. 555, 65-80
58. Gescher, A. J., and Steward, W. P. (2003) Cancer Epidemiol. Biomarkers Prev. 12, 953-957
59. Granados-Soto, V. (2003) Drug News Perspect. 16, 299-307
60. Kaeberlein, M., Kirkland, K. T., Fields, S., and Kennedy, B. K. (2004) PLoS Biol. 2, E296
61. Borra, M. T., and Denu, J. M. (2004) Methods Enzymol. 376, 171-187
62. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723
63. Avalos, J. L., Celic, I., Muhammad, S., Cosgrove, M. S., Boeke, J. D., and Wolberger, C. (2002) Mol. Cell 10, 523-535
64. Wegener, D., Wirsching, F., Riester, D., and Schwienhorst, A. (2003) Chem. Biol. 10, 61-68
65. Marcotte, P. A., Richardson, P. R., Guo, J., Barrett, L. W., Xu, N., Gunasekera, A., and Glaser, K. B. (2004) Anal. Biochem. 332, 90-99
66. Copeland, R. A. (2000) Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis, pp. 276-277, 2nd Ed., John Wiley & Sons, Inc., New York
67. Blander, G., Olejnik, J., Krzymanska-Olejnik, E., McDonagh, T., Haigis, M., Yaffe, M. B., and Guarente, L. (2005) J. Biol. Chem. 280, 9780-9785