-
1
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments
-
Alonso A. Zaidi T. Novak M. Grundke-Iqbal I. Iqbal K. Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments Proc. Natl. Acad. Sci. U. S. A. 98 2001 6923 6928
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 6923-6928
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
3
-
-
0035689651
-
Behavioral assessment of Alzheimer's transgenic mice following long-term Aβ vaccination: task specificity and correlations between Aβ deposition and spatial memory
-
Arendash G.W. Gordon M.N. Diamond D.M. Austin L.A. Hatcher J.M. Jantzen P. Dicarlo G. Wilcock D. Morgan D. Behavioral assessment of Alzheimer's transgenic mice following long-term Aβ vaccination: task specificity and correlations between Aβ deposition and spatial memory DNA Cell Biol. 20 2001 737 744
-
(2001)
DNA Cell Biol.
, vol.20
, pp. 737-744
-
-
Arendash, G.W.1
Gordon, M.N.2
Diamond, D.M.3
Austin, L.A.4
Hatcher, J.M.5
Jantzen, P.6
Dicarlo, G.7
Wilcock, D.8
Morgan, D.9
-
4
-
-
2442587216
-
Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's Disease: linkage of poorer cognitive performance to tau pathology in forebrain
-
Arendash G.W. Lewis J. Leighty R.E. McGowan E. Cracchiolo J.R. Hutton M. Garcia M.F. Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's Disease: linkage of poorer cognitive performance to tau pathology in forebrain Brain Res. 1012 2004 29 41
-
(2004)
Brain Res.
, vol.1012
, pp. 29-41
-
-
Arendash, G.W.1
Lewis, J.2
Leighty, R.E.3
McGowan, E.4
Cracchiolo, J.R.5
Hutton, M.6
Garcia, M.F.7
-
5
-
-
33750984544
-
Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production
-
Arendash G.W. Schleif W. Rezai-Zadeh K. Jackson E.K. Zacharia L.C. Cracchiolo J.R. Shippy D. Tan J. Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production Neuroscience 142 2006 941 952
-
(2006)
Neuroscience
, vol.142
, pp. 941-952
-
-
Arendash, G.W.1
Schleif, W.2
Rezai-Zadeh, K.3
Jackson, E.K.4
Zacharia, L.C.5
Cracchiolo, J.R.6
Shippy, D.7
Tan, J.8
-
6
-
-
0031596660
-
Phosphorylation of tau, Abeta-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A
-
Arendt T. Holzer M. Fruth R. Bruckner M.K. Gartner U. Phosphorylation of tau, Abeta-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A Neurobiol. Aging 19 1998 3 13
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 3-13
-
-
Arendt, T.1
Holzer, M.2
Fruth, R.3
Bruckner, M.K.4
Gartner, U.5
-
7
-
-
0025949088
-
A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities
-
Brion J.P. Hanger D.P. Couck A.M. Anderton B.H. A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities Biochem. J. 279 1991 831 836
-
(1991)
Biochem. J.
, vol.279
, pp. 831-836
-
-
Brion, J.P.1
Hanger, D.P.2
Couck, A.M.3
Anderton, B.H.4
-
8
-
-
0028986916
-
β-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding
-
Busciglio J. Lorenzo A. Yeh J. Yankner B.A. β-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding Neuron 14 1995 879 888
-
(1995)
Neuron
, vol.14
, pp. 879-888
-
-
Busciglio, J.1
Lorenzo, A.2
Yeh, J.3
Yankner, B.A.4
-
9
-
-
0032558784
-
Neuron loss in APP transgenic mice
-
Calhoun M. Wiederhold K. Abramowski D. Phinney A.L. Sturchler-Pierrat C. Staufenbiel M. Sommer B. Jucker M. Neuron loss in APP transgenic mice Nature 395 1998 755 756
-
(1998)
Nature
, vol.395
, pp. 755-756
-
-
Calhoun, M.1
Wiederhold, K.2
Abramowski, D.3
Phinney, A.L.4
Sturchler-Pierrat, C.5
Staufenbiel, M.6
Sommer, B.7
Jucker, M.8
-
10
-
-
0032556859
-
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
De Strooper B. Saftig P. Craessaerts K. Vanderstichele H. Guhde G. Annaert W. Von Figura K. Van Leuven F. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein Nature 391 1998 387 390
-
(1998)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Guhde, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
11
-
-
33847369469
-
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
-
Dickey C.A. Kamal A. Lundgren K. Klosak N. Bailey R.M. Dunmore J. Ash P. Shoraka S. Zlatkovic J. Eckman C.B. Patterson C. Dickson D.W. Nahman N.S. Hutton M. Burrows F. Petrucelli L. The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins J. Clin. Invest. 117 2007 648 658
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 648-658
-
-
Dickey, C.A.1
Kamal, A.2
Lundgren, K.3
Klosak, N.4
Bailey, R.M.5
Dunmore, J.6
Ash, P.7
Shoraka, S.8
Zlatkovic, J.9
Eckman, C.B.10
Patterson, C.11
Dickson, D.W.12
Nahman, N.S.13
Hutton, M.14
Burrows, F.15
Petrucelli, L.16
-
12
-
-
6344265522
-
Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42
-
Funamoto S. Morishima-Kawashima M. Tanimura Y. Hirotani N. Saido T.C. Ihara Y. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42 Biochemistry 43 2004 13532 13540
-
(2004)
Biochemistry
, vol.43
, pp. 13532-13540
-
-
Funamoto, S.1
Morishima-Kawashima, M.2
Tanimura, Y.3
Hirotani, N.4
Saido, T.C.5
Ihara, Y.6
-
13
-
-
0029841562
-
Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain
-
Furukawa K. Sopher B.L. Rydel R.E. Begley J.G. Pham D.G. Martin G.M. Fox M. Mattson M.P. Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain J. Neurochem. 67 1996 1882 1896
-
(1996)
J. Neurochem.
, vol.67
, pp. 1882-1896
-
-
Furukawa, K.1
Sopher, B.L.2
Rydel, R.E.3
Begley, J.G.4
Pham, D.G.5
Martin, G.M.6
Fox, M.7
Mattson, M.P.8
-
14
-
-
0030005625
-
Tau protein and the neurofibrillary pathology of Alzheimer's disease
-
Goedert M. Tau protein and the neurofibrillary pathology of Alzheimer's disease Ann. N. Y. Acad. Sci. 777 1996 121 131
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.777
, pp. 121-131
-
-
Goedert, M.1
-
15
-
-
0034718027
-
Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease
-
Golde T.E. Eckman C.B. Younkin S.G. Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease Biochim. Biophys. Acta 1502 2000 172 187
-
(2000)
Biochim. Biophys. Acta
, vol.1502
, pp. 172-187
-
-
Golde, T.E.1
Eckman, C.B.2
Younkin, S.G.3
-
16
-
-
0025292866
-
Preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis
-
Greenberg S.G. Davies P.A. Preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis Proc. Natl. Acad. Sci. U. S. A. 87 1990 5827 5831
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 5827-5831
-
-
Greenberg, S.G.1
Davies, P.A.2
-
17
-
-
0029018851
-
Secreted β-APP stimulates MAP kinase and phosphorylation of tau in neurons
-
Greenberg S.M. Kosik K.S. Secreted β-APP stimulates MAP kinase and phosphorylation of tau in neurons Neurobiol. Aging 16 1995 403 408
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 403-408
-
-
Greenberg, S.M.1
Kosik, K.S.2
-
20
-
-
0036262945
-
The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease
-
Hooper N.M. Turner A.J. The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease Curr. Med. Chem. 9 2002 1107 1119
-
(2002)
Curr. Med. Chem.
, vol.9
, pp. 1107-1119
-
-
Hooper, N.M.1
Turner, A.J.2
-
21
-
-
0029742199
-
Correlative memory deficits, A elevation, and amyloid plaques in transgenic mice
-
Hsiao K. Chapman P. Nilsen S. Eckman C. Harigaya Y. Younkin S. Yang F. Cole G. Correlative memory deficits, A elevation, and amyloid plaques in transgenic mice Science 274 1996 99 102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
22
-
-
0034966403
-
Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease
-
Huse J.T. Doms R.W. Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease Mol. Neurobiol. 22 2000 81 98
-
(2000)
Mol. Neurobiol.
, vol.22
, pp. 81-98
-
-
Huse, J.T.1
Doms, R.W.2
-
23
-
-
0031020909
-
Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease
-
Johnson-Wood K. Lee M. Motter R. Hu K. Gordon G. Barbour R. Khan K. Gordon M. Tan H. Games D. Lieberburg I. Schenk D. Seubert P. McConlogue L. Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease Proc. Natl. Acad. Sci. U. S. A. 94 1997 1550 1555
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 1550-1555
-
-
Johnson-Wood, K.1
Lee, M.2
Motter, R.3
Hu, K.4
Gordon, G.5
Barbour, R.6
Khan, K.7
Gordon, M.8
Tan, H.9
Games, D.10
Lieberburg, I.11
Schenk, D.12
Seubert, P.13
McConlogue, L.14
-
24
-
-
0037088956
-
Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months
-
King D.L. Arendash G.W. Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months Physiol. Behav. 75 2002 627 642
-
(2002)
Physiol. Behav.
, vol.75
, pp. 627-642
-
-
King, D.L.1
Arendash, G.W.2
-
25
-
-
10944273982
-
Phosphorylated tau and the neurodegenerative foldopathies
-
Kosik K.S. Shimura H. Phosphorylated tau and the neurodegenerative foldopathies Biochim. Biophys. Acta. 1739 2005 298 310
-
(2005)
Biochim. Biophys. Acta.
, vol.1739
, pp. 298-310
-
-
Kosik, K.S.1
Shimura, H.2
-
26
-
-
0345168968
-
Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice
-
Lambert J.D. Lee M.J. Lu H. Meng X. Hong J.J. Seril D.N. Sturgill M.G. Yang C.S. Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice J. Nutr. 133 2003 4172 4177
-
(2003)
J. Nutr.
, vol.133
, pp. 4172-4177
-
-
Lambert, J.D.1
Lee, M.J.2
Lu, H.3
Meng, X.4
Hong, J.J.5
Seril, D.N.6
Sturgill, M.G.7
Yang, C.S.8
-
28
-
-
3042694083
-
Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer's transgenic mouse lines differing in Aβ deposition.
-
Leighty R.E. Nilsson L. Potter H. Costa D.A. Low M.A. Bales K.R. Paul S.M. Arendash G.W. Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer's transgenic mouse lines differing in Aβ deposition. Behav. Brain Res. 153 2004 107 121
-
(2004)
Behav. Brain Res.
, vol.153
, pp. 107-121
-
-
Leighty, R.E.1
Nilsson, L.2
Potter, H.3
Costa, D.A.4
Low, M.A.5
Bales, K.R.6
Paul, S.M.7
Arendash, G.W.8
-
29
-
-
0038661168
-
Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (−)epigallocatechin-3-gallate
-
Levites Y. Amit T. Mandel S. Youdim M.B. Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (−)epigallocatechin-3-gallate FASEB J. 17 2003 952 954
-
(2003)
FASEB J.
, vol.17
, pp. 952-954
-
-
Levites, Y.1
Amit, T.2
Mandel, S.3
Youdim, M.B.4
-
30
-
-
85047694415
-
Amyloid at the cutting edge: activation of alpha-secretase prevents amyloidogenesis in an Alzheimer disease mouse model
-
Lichtenthaler S.F. Haass C. Amyloid at the cutting edge: activation of alpha-secretase prevents amyloidogenesis in an Alzheimer disease mouse model J. Clin. Invest. 113 2004 1384 1387
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1384-1387
-
-
Lichtenthaler, S.F.1
Haass, C.2
-
31
-
-
27844497059
-
Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
-
Marambaud P. Zhao H. Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides J. Biol. Chem. 280 2005 37377 37382
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37377-37382
-
-
Marambaud, P.1
Zhao, H.2
Davies, P.3
-
32
-
-
0031054724
-
Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease
-
Mattson M.P. Barger S.W. Furukawa K. Bruce A.J. Wyss-Coray T. Mark R.J. Mucke L. Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease Brain Res. Brain Res. Rev. 23 1997 47 61
-
(1997)
Brain Res. Brain Res. Rev.
, vol.23
, pp. 47-61
-
-
Mattson, M.P.1
Barger, S.W.2
Furukawa, K.3
Bruce, A.J.4
Wyss-Coray, T.5
Mark, R.J.6
Mucke, L.7
-
33
-
-
0344483869
-
Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism
-
Mattson M.P. Guo Z.H. Geiger J.D. Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism J. Neurochem. 73 1999 532 537
-
(1999)
J. Neurochem.
, vol.73
, pp. 532-537
-
-
Mattson, M.P.1
Guo, Z.H.2
Geiger, J.D.3
-
34
-
-
33745209915
-
ADAM10 Activation Is Required for Green Tea EGCG-induced α-Secretase Cleavage of Amyloid Precursor Protein
-
Obregon D. Rezai-Zadeh K. Bai Y. Sun N. Hou H. Zeng J. Mori T. Arendash G.W. Shytle D. Town T. Tan J. ADAM10 Activation Is Required for Green Tea EGCG-induced α-Secretase Cleavage of Amyloid Precursor Protein J. Biol. Chem. 281 2006 16419 16427
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16419-16427
-
-
Obregon, D.1
Rezai-Zadeh, K.2
Bai, Y.3
Sun, N.4
Hou, H.5
Zeng, J.6
Mori, T.7
Arendash, G.W.8
Shytle, D.9
Town, T.10
Tan, J.11
-
35
-
-
16344364163
-
Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein
-
Palermo C.M. Westlake C.A. Gasiewicz T.A. Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein Biochemistry 44 2005 5041 5052
-
(2005)
Biochemistry
, vol.44
, pp. 5041-5052
-
-
Palermo, C.M.1
Westlake, C.A.2
Gasiewicz, T.A.3
-
36
-
-
25444500410
-
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice
-
Rezai-Zadeh K. Shytle D. Sun N. Mori T. Hou H. Jeanniton D. Ehrhart J. Townsend K. Zeng J. Morgan D. Hardy J. Town T. Tan J. Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice J. Neurosci. 25 2005 8807 8814
-
(2005)
J. Neurosci.
, vol.25
, pp. 8807-8814
-
-
Rezai-Zadeh, K.1
Shytle, D.2
Sun, N.3
Mori, T.4
Hou, H.5
Jeanniton, D.6
Ehrhart, J.7
Townsend, K.8
Zeng, J.9
Morgan, D.10
Hardy, J.11
Town, T.12
Tan, J.13
-
37
-
-
0036370776
-
Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease
-
Sambamurti K. Greig N.H. Lahiri D.K. Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease Neuromolecular Med. 1 2002 1 31
-
(2002)
Neuromolecular Med.
, vol.1
, pp. 1-31
-
-
Sambamurti, K.1
Greig, N.H.2
Lahiri, D.K.3
-
39
-
-
0027236786
-
Alzheimer disease A68 proteins injected into rat brain induce codeposits of beta-amyloid, ubiquitin, and alpha 1-antichymotrypsin
-
Shin R.W. Bramblett G.T. Lee V.M. Trojanowski J.Q. Alzheimer disease A68 proteins injected into rat brain induce codeposits of beta-amyloid, ubiquitin, and alpha 1-antichymotrypsin Proc. Natl. Acad. Sci. U. S. A. 90 1993 6825 6828
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 6825-6828
-
-
Shin, R.W.1
Bramblett, G.T.2
Lee, V.M.3
Trojanowski, J.Q.4
-
40
-
-
0033613129
-
Cellular mechanisms of beta-amyloid production and secretion
-
Sinha S. Lieberburg I. Cellular mechanisms of beta-amyloid production and secretion Proc. Natl. Acad. Sci. U. S. A. 96 1999 11049 11053
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11049-11053
-
-
Sinha, S.1
Lieberburg, I.2
-
41
-
-
4444255624
-
Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis
-
Stein T.D. Anders N.J. DeCarli C. Chan S.L. Mattson M.P. Johnson J.A. Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis J. Neurosci. 24 2004 7707 7717
-
(2004)
J. Neurosci.
, vol.24
, pp. 7707-7717
-
-
Stein, T.D.1
Anders, N.J.2
DeCarli, C.3
Chan, S.L.4
Mattson, M.P.5
Johnson, J.A.6
-
42
-
-
0033214070
-
A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling
-
Steiner H. Duff K. Capell A. Romig H. Grim M.G. Lincoln S. Hardy J. Yu X. Picciano M. Fechteler K. Citron M. Kopan R. Pesold B. Keck S. Baader M. Tomita T. Iwatsubo T. Baumeister R. Haass C. A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling J. Biol. Chem. 274 1999 28669 28673
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28669-28673
-
-
Steiner, H.1
Duff, K.2
Capell, A.3
Romig, H.4
Grim, M.G.5
Lincoln, S.6
Hardy, J.7
Yu, X.8
Picciano, M.9
Fechteler, K.10
Citron, M.11
Kopan, R.12
Pesold, B.13
Keck, S.14
Baader, M.15
Tomita, T.16
Iwatsubo, T.17
Baumeister, R.18
Haass, C.19
-
43
-
-
0031595920
-
Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue
-
Suganuma M. Okabe S. Oniyama M. Tada Y. Ito H. Fujiki H. Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue Carcinogenesis 19 1998 1771 1776
-
(1998)
Carcinogenesis
, vol.19
, pp. 1771-1776
-
-
Suganuma, M.1
Okabe, S.2
Oniyama, M.3
Tada, Y.4
Ito, H.5
Fujiki, H.6
-
44
-
-
0036900076
-
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice
-
Tan J. Town T. Crawford F. Mori T. DelleDonne A. Crescentini R. Obregon D. Flavell R.A. Mullan M.J. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice Nat. Neurosci. 5 2002 1288 1293
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 1288-1293
-
-
Tan, J.1
Town, T.2
Crawford, F.3
Mori, T.4
DelleDonne, A.5
Crescentini, R.6
Obregon, D.7
Flavell, R.A.8
Mullan, M.J.9
-
45
-
-
0033595706
-
beta-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R. Bennett B.D. Babu-Khan S. Kahn S. Mendiaz F. Denis P. Teplow D.B. Ross S. Amarante P. Loeloff R. Luo Y. Fisher S. Fuller J. Edenson S. Lile J. Jarosinski M.A. Biere A.L. Curran E. Burgess T. Louis J.C. Collins F. Treanor J. Rogers G. Citron M. beta-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE Science 286 1999 735 741
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, F.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
46
-
-
0032566623
-
Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase
-
Wang J.Z. Wu Q. Smith A. Grundke-Iqbal I. Iqbal K. Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase FEBS Lett. 436 1998 28 34
-
(1998)
FEBS Lett.
, vol.436
, pp. 28-34
-
-
Wang, J.Z.1
Wu, Q.2
Smith, A.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
47
-
-
0036919644
-
Phosphorylation of microtubule-associated protein tau by Ca2+/calmodulin-dependent protein kinase II in its tubulin binding sites
-
Yamamoto H. Yamauchi E. Taniguchi H. Ono T. Miyamoto E. Phosphorylation of microtubule-associated protein tau by Ca2+/calmodulin-dependent protein kinase II in its tubulin binding sites Arch. Biochem. Biophys. 408 2002 255 262
-
(2002)
Arch. Biochem. Biophys.
, vol.408
, pp. 255-262
-
-
Yamamoto, H.1
Yamauchi, E.2
Taniguchi, H.3
Ono, T.4
Miyamoto, E.5
-
48
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
-
Yan R. Bienkowski M.J. Shuck M.E. Miao H. Tory M.C. Pauley A.M. Brashier J.R. Stratman N.C. Mathews W.R. Buhl A.E. Carter D.B. Tomasselli A.G. Parodi L.A. Heinrikson R.L. Gurney M.E. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity Nature 402 1999 533 537
-
(1999)
Nature
, vol.402
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
Brashier, J.R.7
Stratman, N.C.8
Mathews, W.R.9
Buhl, A.E.10
Carter, D.B.11
Tomasselli, A.G.12
Parodi, L.A.13
Heinrikson, R.L.14
Gurney, M.E.15
-
49
-
-
20044370990
-
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo
-
Yang F. Lim G.P. Begum A.N. Ubeda O.J. Simmons M.R. Ambegaokar S.S. Chen P.P. Kayed R. Glabe C.G. Frautschy S.A. Cole G.M. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo J. Biol. Chem. 280 2005 5892 5901
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5892-5901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
Ubeda, O.J.4
Simmons, M.R.5
Ambegaokar, S.S.6
Chen, P.P.7
Kayed, R.8
Glabe, C.G.9
Frautschy, S.A.10
Cole, G.M.11
|