Recent progress in phospholipase A2 research: From cells to animals to humans

Progress in Lipid Research

Volumn 50, Issue 2, 2011, Pages 152-192

  Murakami, Makoto ^a   Taketomi, Yoshitaka ^a   Miki, Yoshimi ^a   Sato, Hiroyasu ^a   Hirabayashi, Tetsuya ^a   Yamamoto, Kei ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Human disease; Knockout mouse; Lipid mediator; Membrane; Phospholipase A2; Phospholipid; Transgenic mouse

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; A 001; A 002; ARACHIDONIC ACID; CALCIUM INDEPENDENT PHOSPHOLIPASE A2; CYTOSOLIC PHOSPHOLIPASE A2; ECOPLADIB; EFIPLADIB; LYSOPHOSPHOLIPASE; PEROXIREDOXIN 6; PHOSPHOLIPASE A2 GROUP IB; PHOSPHOLIPASE A2 INHIBITOR; RECEPTOR; SECRETORY PHOSPHOLIPASE A2; UNCLASSIFIED DRUG; VARESPLADIB; WAY 196025;

ARTHRITIS; ASTHMA; ATHEROSCLEROSIS; DEFENSE MECHANISM; EUKARYOTE; EXTRACELLULAR SPACE; FATTY ACID METABOLISM; HUMAN; INFLAMMATION; INTRACELLULAR MEMBRANE; KNOCKOUT MOUSE; MULTIPLE SCLEROSIS; NEOPLASM; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; TRANSGENIC MOUSE;

ANIMALS; HUMANS; LIPID METABOLISM; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHOSPHOLIPASES A2, CALCIUM-INDEPENDENT; PHOSPHOLIPASES A2, CYTOSOLIC; PHOSPHOLIPASES A2, SECRETORY;

ANIMALIA; EUKARYOTA; MAMMALIA; MUS MUSCULUS; VERTEBRATA;

EID: 79952080909     PISSN: 01637827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plipres.2010.12.001     Document Type: Review

References (599)

1. M. Murakami, Y. Taketomi, C. Girard, K. Yamamoto, and G. Lambeau Biochimie 92 2010 561 582
2. T.M. McIntyre, S.M. Prescott, and D.M. Stafforini J Lipid Res 50 Suppl. 2009 S255 S259
3. G. Lambeau, and M.H. Gelb Annu Rev Biochem 77 2008 495 520
4. I. Kudo, and M. Murakami Prostaglandins Other Lipid Mediat 68-69 2002 3 58
5. Y. Kita, T. Ohto, N. Uozumi, and T. Shimizu Biochim Biophys Acta 1761 2006 1317 1322
6. P.C. Kienesberger, M. Oberer, A. Lass, and R. Zechner J Lipid Res 50 Suppl 2009 S63 S68
7. M. Ghosh, D.E. Tucker, S.A. Burchett, and C.C. Leslie Prog Lipid Res 45 2006 487 510
8. J. Balsinde, and M.A. Balboa Cell Signal 17 2005 1052 1062
9. H. Arai Prostaglandins Other Lipid Mediat 68-69 2002 83 94
10. J.A. Tischfield, Y.R. Xia, D.M. Shih, I. Klisak, J. Chen, and S.J. Engle Genomics 32 1996 328 333
11. E. Valentin, A.G. Singer, F. Ghomashchi, M. Lazdunski, M.H. Gelb, and G. Lambeau Biochem Biophys Res Commun 279 2000 223 228
12. J.J. Seilhamer, T.L. Randall, M. Yamanaka, and L.K. Johnson DNA 5 1986 519 527
13. H.M. Verheij, A.J. Slotboom, and G.H. De Haas Rev Physiol Biochem Pharmacol 91 1981 91 203
14. I. Kudo, M. Murakami, S. Hara, and K. Inoue Biochim Biophys Acta 1170 1993 217 231
15. R.M. Kramer, C. Hession, B. Johansen, G. Hayes, P. McGray, and E.P. Chow J Biol Chem 264 1989 5768 5775
16. J.J. Seilhamer, W. Pruzanski, P. Vadas, S. Plant, J.A. Miller, and J. Kloss J Biol Chem 264 1989 5335 5338
17. T. Nakano, O. Ohara, H. Teraoka, and H. Arita FEBS Lett 261 1990 171 174
18. R.M. Crowl, T.J. Stoller, R.R. Conroy, and C.R. Stoner J Biol Chem 266 1991 2647 2651
19. S. Oka, and H. Arita J Biol Chem 266 1991 9956 9960
20. J. Pfeilschifter, H. Muhl, W. Pignat, F. Marki, and H. Van den Bosch Eur J Clin Pharmacol 44 Suppl 1 1993 S7 S9
21. C.O. Bingham 3rd, M. Murakami, H. Fujishima, J.E. Hunt, K.F. Austen, and J.P. Arm J Biol Chem 271 1996 25936 25944
22. C. Couturier, A. Brouillet, C. Couriaud, K. Koumanov, G. Bereziat, and M. Andreani J Biol Chem 274 1999 23085 23093
23. H. Kuwata, S. Yamamoto, Y. Miyazaki, S. Shimbara, Y. Nakatani, and H. Suzuki J Immunol 165 2000 4024 4031
24. H. Peilot, B. Rosengren, G. Bondjers, and E. Hurt-Camejo J Biol Chem 275 2000 22895 22904
25. C. Massaad, M. Paradon, C. Jacques, C. Salvat, G. Bereziat, and F. Berenbaum J Biol Chem 275 2000 22686 22694
26. S. Akiba, R. Hatazawa, K. Ono, K. Kitatani, M. Hayama, and T. Sato J Biol Chem 276 2001 21854 21862
27. M. Murakami, S. Shimbara, T. Kambe, H. Kuwata, M.V. Winstead, and J.A. Tischfield J Biol Chem 273 1998 14411 14423
28. M. Murakami, T. Kambe, S. Shimbara, S. Yamamoto, H. Kuwata, and I. Kudo J Biol Chem 274 1999 29927 29936
29. M. Murakami, R.S. Koduri, A. Enomoto, S. Shimbara, M. Seki, and K. Yoshihara J Biol Chem 276 2001 10083 10096
30. H. Kuwata, Y. Nakatani, M. Murakami, and I. Kudo J Biol Chem 273 1998 1733 1740
31. R.S. Koduri, S.F. Baker, Y. Snitko, S.K. Han, W. Cho, and D.C. Wilton J Biol Chem 273 1998 32142 32153
32. M. Murakami, I. Kudo, and K. Inoue Biochim Biophys Acta 1005 1989 270 276
33. K.P. Kim, J.D. Rafter, L. Bittova, S.K. Han, Y. Snitko, and N.M. Munoz J Biol Chem 276 2001 11126 11134
34. C.M. Mounier, F. Ghomashchi, M.R. Lindsay, S. James, A.G. Singer, and R.G. Parton J Biol Chem 279 2004 25024 25038
35. O. Fourcade, M.F. Simon, C. Viode, N. Rugani, F. Leballe, and A. Ragab Cell 80 1995 919 927
36. G. Atsumi, M. Murakami, M. Tajima, S. Shimbara, N. Hara, and I. Kudo Biochim Biophys Acta 1349 1997 43 54
37. Y. Snitko, E.T. Yoon, and W. Cho Biochem J 321 Pt 3 1997 737 741
38. J. Chen, S.J. Engle, J.J. Seilhamer, and J.A. Tischfield J Biol Chem 269 1994 23018 23024
39. J. Chen, C. Shao, V. Lazar, C.H. Srivastava, W.H. Lee, and J.A. Tischfield J Cell Biochem 64 1997 369 375
40. E. Valentin, R.S. Koduri, J.C. Scimeca, G. Carle, M.H. Gelb, and M. Lazdunski J Biol Chem 274 1999 19152 19160
41. J. Ishizaki, N. Suzuki, K. Higashino, Y. Yokota, T. Ono, and K. Kawamoto J Biol Chem 274 1999 24973 24979
42. M. Murakami, K. Yoshihara, S. Shimbara, M. Sawada, N. Inagaki, and H. Nagai Eur J Biochem 269 2002 2698 2707
43. M. Golik, M. Cohen-Zinder, J.J. Loor, J.K. Drackley, M.R. Band, and H.A. Lewin Genomics 87 2006 527 533
44. N. Suzuki, J. Ishizaki, Y. Yokota, K. Higashino, T. Ono, and M. Ikeda J Biol Chem 275 2000 5785 5793
45. A.G. Singer, F. Ghomashchi, C. Le Calvez, J. Bollinger, S. Bezzine, and M. Rouault J Biol Chem 277 2002 48535 48549
46. E. Valentin, F. Ghomashchi, M.H. Gelb, M. Lazdunski, and G. Lambeau J Biol Chem 274 1999 31195 31202
47. M. Murakami, K. Yoshihara, S. Shimbara, G. Lambeau, M.H. Gelb, and A.G. Singer J Biol Chem 277 2002 19145 19155
48. G.T. Wijewickrama, A. Albanese, Y.J. Kim, Y.S. Oh, P.S. Murray, and R. Takayanagi J Biol Chem 281 2006 32741 32754
49. J. Chen, S.J. Engle, J.J. Seilhamer, and J.A. Tischfield J Biol Chem 269 1994 2365 2368
50. M. Murakami, T. Kambe, S. Shimbara, and I. Kudo J Biol Chem 274 1999 3103 3115
51. M.A. Balboa, Y. Shirai, G. Gaietta, M.H. Ellisman, J. Balsinde, and E.A. Dennis J Biol Chem 278 2003 48059 48065
52. Y.J. Kim, K.P. Kim, H.J. Rhee, S. Das, J.D. Rafter, and Y.S. Oh J Biol Chem 277 2002 9358 9365
53. S.K. Han, K.P. Kim, R. Koduri, L. Bittova, N.M. Munoz, and A.R. Leff J Biol Chem 274 1999 11881 11888
54. Y.J. Kim, K.P. Kim, S.K. Han, N.M. Munoz, X. Zhu, and H. Sano J Biol Chem 277 2002 36479 36488
55. N.M. Munoz, Y.J. Kim, A.Y. Meliton, K.P. Kim, S.K. Han, and E. Boetticher J Biol Chem 278 2003 38813 38820
56. G.T. Wijewickrama, J.H. Kim, Y.J. Kim, A. Abraham, Y. Oh, and B. Ananthanarayanan J Biol Chem 281 2006 10935 10944
57. N.M. Munoz, A.Y. Meliton, A. Lambertino, E. Boetticher, J. Learoyd, and F. Sultan J Immunol 177 2006 574 582
58. R.D. Hite, M.C. Seeds, R.B. Jacinto, R. Balasubramanian, M. Waite, and D. Bass Am J Physiol 275 1998 L740 L747
59. M. Ohtsuki, Y. Taketomi, S. Arata, S. Masuda, Y. Ishikawa, and T. Ishii J Biol Chem 281 2006 36420 36433
60. L. Gesquiere, W. Cho, and P.V. Subbaiah Biochemistry 41 2002 4911 4920
61. C.R. Wooton-Kee, B.B. Boyanovsky, M.S. Nasser, W.J. de Villiers, and N.R. Webb Arterioscler Thromb Vasc Biol 24 2004 762 767
62. Y. Ishimoto, K. Yamada, S. Yamamoto, T. Ono, M. Notoya, and K. Hanasaki Biochim Biophys Acta 1642 2003 129 138
63. W. Pruzanski, L. Lambeau, M. Lazdunsky, W. Cho, J. Kopilov, and A. Kuksis Biochim Biophys Acta 1736 2005 38 50
64. M. Mitsuishi, S. Masuda, I. Kudo, and M. Murakami Biochim Biophys Acta 1771 2007 1389 1396
65. Y. Chen, and E.A. Dennis Biochim Biophys Acta 1394 1998 57 64
66. L. Cupillard, K. Koumanov, M.G. Mattei, M. Lazdunski, and G. Lambeau J Biol Chem 272 1997 15745 15752
67. Y. Morioka, A. Saiga, Y. Yokota, N. Suzuki, M. Ikeda, and T. Ono Arch Biochem Biophys 381 2000 31 42
68. S. Masuda, M. Murakami, M. Mitsuishi, K. Komiyama, Y. Ishikawa, and T. Ishii Biochem J 387 2005 27 38
69. K. Hamaguchi, H. Kuwata, K. Yoshihara, S. Masuda, S. Shimbara, and S. Oh-ishi Biochim Biophys Acta 1635 2003 37 47
70. S. Masuda, M. Murakami, Y. Takanezawa, J. Aoki, H. Arai, and Y. Ishikawa J Biol Chem 280 2005 23203 23214
71. Y.H. Pan, B.Z. Yu, A.G. Singer, F. Ghomashchi, G. Lambeau, and M.H. Gelb J Biol Chem 277 2002 29086 29093
72. K. Hanasaki, T. Ono, A. Saiga, Y. Morioka, M. Ikeda, and K. Kawamoto J Biol Chem 274 1999 34203 34211
73. M. Murakami, T. Kambe, S. Shimbara, K. Higashino, K. Hanasaki, and H. Arita J Biol Chem 274 1999 31435 31444
74. S. Bezzine, R.S. Koduri, E. Valentin, M. Murakami, I. Kudo, and F. Ghomashchi J Biol Chem 275 2000 3179 3191
75. K. Hanasaki, K. Yamada, S. Yamamoto, Y. Ishimoto, A. Saiga, and T. Ono J Biol Chem 277 2002 29116 29124
76. S.A. Karabina, I. Brocheriou, G. Le Naour, M. Agrapart, H. Durand, and M. Gelb FASEB J 20 2006 2547 2549
77. E. Valentin, F. Ghomashchi, M.H. Gelb, M. Lazdunski, and G. Lambeau J Biol Chem 275 2000 7492 7496
78. M. Murakami, S. Masuda, S. Shimbara, Y. Ishikawa, T. Ishii, and I. Kudo J Biol Chem 280 2005 24987 24998
79. M.H. Gelb, E. Valentin, F. Ghomashchi, M. Lazdunski, and G. Lambeau J Biol Chem 275 2000 39823 39826
80. I.C. Ho, J.P. Arm, C.O. Bingham 3rd, A. Choi, K.F. Austen, and L.H. Glimcher J Biol Chem 276 2001 18321 18326
81. M. Rouault, J.G. Bollinger, M. Lazdunski, M.H. Gelb, and G. Lambeau Biochemistry 42 2003 11494 11503
82. M.C. Carey, D.M. Small, and C.M. Bliss Annu Rev Physiol 45 1983 651 677
83. I. Ikeda, K. Imaizumi, and M. Sugano Biochim Biophys Acta 921 1987 245 253
84. S.C. Young, and D.Y. Hui Biochem J 339 Pt 3 1999 615 620
85. D. Gilham, E.D. Labonte, J.C. Rojas, R.J. Jandacek, P.N. Howles, and D.Y. Hui J Biol Chem 282 2007 24642 24649
86. K.W. Huggins, A.C. Boileau, and D.Y. Hui Am J Physiol Endocrinol Metab 283 2002 E994 E1001
87. E.D. Labonte, R.J. Kirby, N.M. Schildmeyer, A.M. Cannon, K.W. Huggins, and D.Y. Hui Diabetes 55 2006 935 941
88. E.D. Labonte, P.T. Pfluger, J.G. Cash, D.G. Kuhel, J.C. Roja, and D.P. Magness FASEB J 24 2010 2516 2524
89. S.G. Wilson, G. Adam, M. Langdown, R. Reneland, A. Braun, and T. Andrew Eur J Hum Genet 14 2006 340 348
90. D.Y. Hui, M.J. Cope, E.D. Labonte, H.T. Chang, J. Shao, and E. Goka Br J Pharmacol 157 2009 1263 1269
91. B.L. Richmond, A.C. Boileau, S. Zheng, K.W. Huggins, N.A. Granholm, and P. Tso Gastroenterology 120 2001 1193 1202
92. T. Lu, M. Ito, U. Tchoua, H. Takemori, M. Okamoto, and H. Tojo Biochemistry 40 2001 7133 7139
93. F. Surrel, I. Jemel, E. Boilard, J.G. Bollinger, C. Payre, and C.M. Mounier Mol Pharmacol 76 2009 778 790
94. M. MacPhee, K.P. Chepenik, R.A. Liddell, K.K. Nelson, L.D. Siracusa, and A.M. Buchberg Cell 81 1995 957 966
95. B.P. Kennedy, P. Payette, J. Mudgett, P. Vadas, W. Pruzanski, and M. Kwan J Biol Chem 270 1995 22378 22385
96. M. Kakutani, M. Murakami, H. Okamoto, I. Kudo, and K. Inoue FEBS Lett 339 1994 76 78
97. B. Gil, M.J. Sanz, M.C. Terencio, R. Gunasegaran, M. Paya, and M.J. Alcaraz Biochem Pharmacol 53 1997 733 740
98. P. Garcia Pastor, S. De Rosa, A. De Giulio, M. Paya, and M.J. Alcaraz Br J Pharmacol 126 1999 301 311
99. P. Garcia-Pastor, A. Randazzo, L. Gomez-Paloma, M.J. Alcaraz, and M. Paya J Pharmacol Exp Ther 289 1999 166 172
100. Y. Yokota, K. Hanasaki, T. Ono, H. Nakazato, T. Kobayashi, and H. Arita Biochim Biophys Acta 1438 1999 213 222
101. S. Furue, K. Mikawa, K. Nishina, M. Shiga, M. Ueno, and Y. Tomita Crit Care Med 29 2001 719 727
102. Y. Tomita, H. Jyoyama, M. Kobayashi, K. Kuwabara, S. Furue, and M. Ueno Eur J Pharmacol 472 2003 147 158
103. K. Okamoto, J.S. Kim, and R.K. Rubin Am J Physiol Lung Cell Mol Physiol 292 2007 L62 L67
104. D.S. Grass, R.H. Felkner, M.Y. Chiang, R.E. Wallace, T.J. Nevalainen, and C.F. Bennett J Clin Invest 97 1996 2233 2241
105. E. Boilard, Y. Lai, K. Larabee, B. Balestrieri, F. Ghomashchi, and D. Fujioka EMBO Mol Med 2 2010 172 187
106. O.S. Jamal, P.G. Conaghan, A.M. Cunningham, P.M. Brooks, V.F. Munro, and K.F. Scott Ann Rheum Dis 57 1998 550 558
107. S. Masuda, M. Murakami, K. Komiyama, M. Ishihara, Y. Ishikawa, and T. Ishii FEBS J 272 2005 655 672
108. J.M. McCoy, J.R. Wicks, and L.P. Audoly J Clin Invest 110 2002 651 658
109. D. Kamei, K. Yamakawa, Y. Takegoshi, M. Mikami-Nakanishi, Y. Nakatani, and S. Oh-Ishi J Biol Chem 279 2004 33684 33695
110. T. Honda, E. Segi-Nishida, Y. Miyachi, and S. Narumiya J Exp Med 203 2006 325 335
111. W.H. Shao, A. Del Prete, C.B. Bock, and B. Haribabu J Immunol 176 2006 6254 6261
112. Y. Satake, B.L. Diaz, B. Balestrieri, B.K. Lam, Y. Kanaoka, and M.J. Grusby J Biol Chem 279 2004 16488 16494
113. B.L. Diaz, Y. Satake, E. Kikawada, B. Balestrieri, and J.P. Arm Biochim Biophys Acta 1761 2006 1489 1497
114. E. Kikawada, J.V. Bonventre, and J.P. Arm Blood 110 2007 561 567
115. S. Lapointe, A. Brkovic, I. Cloutier, J.F. Tanguay, J.P. Arm, and M.G. Sirois J Cell Physiol 224 2010 127 134
116. B. Balestrieri, V.W. Hsu, H. Gilbert, C.C. Leslie, W.K. Han, and J.V. Bonventre J Biol Chem 281 2006 6691 6698
117. J.D. Bradley, A.A. Dmitrienko, A.J. Kivitz, O.S. Gluck, A.L. Weaver, and C. Wiesenhutter J Rheumatol 32 2005 417 423
118. T. Matsuoka, M. Hirata, H. Tanaka, Y. Takahashi, T. Murata, and K. Kabashima Science 287 2000 2013 2017
119. Y. Shiraishi, K. Asano, K. Niimi, K. Fukunaga, M. Wakaki, and J. Kagyo J Immunol 180 2008 541 549
120. J. Nakata, M. Kondo, J. Tamaoki, T. Takemiya, M. Nohara, and K. Yamagata Respirology 10 2005 149 156
121. D.C. Zeldin, C. Wohlford-Lenane, P. Chulada, J.A. Bradbury, P.E. Scarborough, and V. Roggli Am J Respir Cell Mol Biol 25 2001 457 465
122. Z. Jaffar, M.E. Ferrini, M.C. Buford, G.A. Fitzgerald, and K. Roberts J Immunol 179 2007 6193 6203
123. T. Kunikata, H. Yamane, E. Segi, T. Matsuoka, Y. Sugimoto, and S. Tanaka Nat Immunol 6 2005 524 531
124. C.G. Irvin, Y.P. Tu, J.R. Sheller, and C.D. Funk Am J Physiol 272 1997 L1053 L1058
125. D.C. Kim, F.I. Hsu, N.A. Barrett, D.S. Friend, R. Grenningloh, and I.C. Ho J Immunol 176 2006 4440 4448
126. A.M. Tager, S.K. Bromley, B.D. Medoff, S.A. Islam, S.D. Bercury, and E.B. Friedrich Nat Immunol 4 2003 982 990
127. B.D. Levy, G.T. De Sanctis, P.R. Devchand, E. Kim, K. Ackerman, and B.A. Schmidt Nat Med 8 2002 1018 1023
128. O. Haworth, M. Cernadas, R. Yang, C.N. Serhan, and B.D. Levy Nat Immunol 9 2008 873 879
129. B.D. Levy, P. Kohli, K. Gotlinger, O. Haworth, S. Hong, and S. Kazani J Immunol 178 2007 496 502
130. S. Ishii, T. Nagase, H. Shindou, H. Takizawa, Y. Ouchi, and T. Shimizu J Immunol 172 2004 7095 7102
131. N. Uozumi, K. Kume, T. Nagase, N. Nakatani, S. Ishii, and F. Tashiro Nature 390 1997 618 622
132. N.M. Munoz, A.Y. Meliton, J.P. Arm, J.V. Bonventre, W. Cho, and A.R. Leff J Immunol 179 2007 4800 4807
133. G. Giannattasio, D. Fujioka, W. Xing, H.R. Katz, J.A. Boyce, and B. Balestrieri J Immunol 2010
134. N.M. Munoz, A.Y. Meliton, L.N. Meliton, S.M. Dudek, and A.R. Leff Am J Physiol Lung Cell Mol Physiol 296 2009 L879 L887
135. W.R. Henderson Jr., E.Y. Chi, J.G. Bollinger, Y.T. Tien, X. Ye, and L. Castelli J Exp Med 204 2007 865 877
136. M.C. Seeds, K.A. Jones, R. Duncan Hite, M.C. Willingham, H.M. Borgerink, and R.D. Woodruff Am J Respir Cell Mol Biol 23 2000 37 44
137. T.S. Hallstrand, E.Y. Chi, A.G. Singer, M.H. Gelb, and W.R. Henderson Jr. Am J Respir Crit Care Med 176 2007 1072 1078
138. F.H. Chilton, F.J. Averill, W.C. Hubbard, A.N. Fonteh, M. Triggiani, and M.C. Liu J Exp Med 183 1996 2235 2245
139. L. Touqui, and M. Alaoui-El-Azher Curr Mol Med 1 2001 739 754
140. L. Arbibe, K. Koumanov, D. Vial, C. Rougeot, G. Faure, and N. Havet J Clin Invest 102 1998 1152 1160
141. B.P. Smart, R.C. Oslund, L.A. Walsh, and M.H. Gelb J Med Chem 49 2006 2858 2860
142. S. Chabot, K. Koumanov, G. Lambeau, M.H. Gelb, V. Balloy, and M. Chignard J Immunol 171 2003 995 1000
143. R. Sato, S. Yamaga, K. Watanabe, S. Hishiyama, K. Kawabata, and T. Kobayashi Exp Lung Res 36 2010 191 200
144. H. Sato, R. Kato, Y. Isogai, G. Saka, M. Ohtsuki, and Y. Taketomi J Biol Chem 283 2008 33483 33497
145. D.M. Curfs, S.A. Ghesquiere, M.N. Vergouwe, I. van der Made, M.J. Gijbels, and D.R. Greaves J Biol Chem 283 2008 21640 21648
146. A. Mantovani, A. Sica, and M. Locati Immunity 23 2005 344 346
147. K. Kang, S.M. Reilly, V. Karabacak, M.R. Gangl, K. Fitzgerald, and B. Hatano Cell Metab 7 2008 485 495
148. I.F. Charo Cell Metab 6 2007 96 98
149. J.I. Odegaard, R.R. Ricardo-Gonzalez, M.H. Goforth, C.R. Morel, V. Subramanian, and L. Mukundan Nature 447 2007 1116 1120
150. C.N. Lumeng, J.L. Bodzin, and A.R. Saltiel J Clin Invest 117 2007 175 184
151. J.M. Olefsky, and C.K. Glass Annu Rev Physiol 72 2010 219 246
152. B. Desvergne Cell Metab 7 2008 467 469
153. D. Namgaladze, D. Morbitzer, A. von Knethen, and B. Brune Arterioscler Thromb Vasc Biol 30 2010 313 320
154. F.O. Martinez, A. Sica, A. Mantovani, and M. Locati Front Biosci 13 2008 453 461
155. R.M. Locksley Cell 140 2010 777 783
156. A.N. Shakhov, A.V. Rubtsov, I.G. Lyakhov, A.V. Tumanov, and S.A. Nedospasov Genes Immun 1 2000 191 199
157. C.E. von Allmen, N. Schmitz, M. Bauer, H.J. Hinton, M.O. Kurrer, and R.B. Buser Proc Natl Acad Sci USA 106 2009 11673 11678
158. J. Lindbom, A.G. Ljungman, and C. Tagesson Inflammation 29 2005 108 117
159. N. Takabatake, M. Sata, S. Inoue, Y. Shibata, S. Abe, and T. Wada Am J Respir Crit Care Med 172 2005 1097 1104
160. A. Igarashi, Y. Shibata, K. Yamauchi, D. Osaka, N. Takabatake, and S. Abe Respiration 78 2009 312 321
161. Z. Liu, X. Lu, H. Wang, X.J. You, Q.X. Gao, and Y.H. Cui Allergy 62 2007 999 1006
162. H. Sato, Y. Taketomi, Y. Isogai, S. Masuda, T. Kobayashi, and K. Yamamoto Biochem J 421 2009 17 27
163. M. Murakami, N. Hara, I. Kudo, and K. Inoue J Immunol 151 1993 5675 5684
164. M. Murakami, K. Tada, S. Shimbara, T. Kambe, H. Sawada, and I. Kudo FEBS Lett 413 1997 249 254
165. A. Enomoto, M. Murakami, E. Valentin, G. Lambeau, M.H. Gelb, and I. Kudo J Immunol 165 2000 4007 4014
166. T. Dudler, D.C. Machado, L. Kolbe, R.R. Annand, N. Rhodes, and M.H. Gelb J Immunol 155 1995 2605 2613
167. Triggiani M, Giannattasio G, Calabrese C, Loffredo S, Granata F, Fiorello A, et al. J Allergy Clin Immunol 2009;124:558-65, 65 e1-3.
168. T.J. Nevalainen, G.G. Graham, and K.F. Scott Biochim Biophys Acta 1781 2008 1 9
169. Y. Weinrauch, C. Abad, N.S. Liang, S.F. Lowry, and J. Weiss J Clin Invest 102 1998 633 638
170. A.K. Foreman-Wykert, Y. Weinrauch, P. Elsbach, and J. Weiss J Clin Invest 103 1999 715 721
171. V.J. Laine, D.S. Grass, and T.J. Nevalainen J Immunol 162 1999 7402 7408
172. V.J. Laine, D.S. Grass, and T.J. Nevalainen Infect Immun 68 2000 87 92
173. A. Piris-Gimenez, M. Paya, G. Lambeau, M. Chignard, M. Mock, and L. Touqui J Immunol 175 2005 6786 6791
174. J. Weiss, G. Wright, A.C. Bekkers, C.J. van den Bergh, and H.M. Verheij J Biol Chem 266 1991 4162 4167
175. T. Koprivnjak, A. Peschel, M.H. Gelb, N.S. Liang, and J.P. Weiss J Biol Chem 277 2002 47636 47644
176. J.O. Gronroos, V.J. Laine, M.J. Janssen, M.R. Egmond, and T.J. Nevalainen J Immunol 166 2001 4029 4034
177. R.S. Koduri, J.O. Gronroos, V.J. Laine, C. Le Calvez, G. Lambeau, and T.J. Nevalainen J Biol Chem 277 2002 5849 5857
178. H.T. Huhtinen, J.O. Gronroos, J.M. Gronroos, J. Uksila, M.H. Gelb, and T.J. Nevalainen APMIS 114 2006 127 130
179. B. Balestrieri, A. Maekawa, W. Xing, M.H. Gelb, H.R. Katz, and J.P. Arm J Immunol 182 2009 4891 4898
180. S. Masuda, M. Murakami, Y. Ishikawa, T. Ishii, and I. Kudo Biochim Biophys Acta 1736 2005 200 210
181. M. Mitsuishi, S. Masuda, I. Kudo, and M. Murakami Biochem J 393 2006 97 106
182. D. Fenard, G. Lambeau, E. Valentin, J.C. Lefebvre, M. Lazdunski, and A. Doglio J Clin Invest 104 1999 611 618
183. L.A. Moreira, J. Ito, A. Ghosh, M. Devenport, H. Zieler, and E.G. Abraham J Biol Chem 277 2002 40839 40843
184. C. Guillaume, C. Deregnaucourt, V. Clavey, and J. Schrevel Toxicon 43 2004 311 318
185. S. Limou, C. Coulonges, M. Foglio, S. Heath, G. Diop, and S. Leclerc Biomed Pharmacother 62 2008 31 40
186. M. Romano, E. Romano, S. Bjorkerud, and E. Hurt-Camejo Arterioscler Thromb Vasc Biol 18 1998 519 525
187. B. Ivandic, L.W. Castellani, X.P. Wang, J.H. Qiao, M. Mehrabian, and M. Navab Arterioscler Thromb Vasc Biol 19 1999 1284 1290
188. E. Hurt-Camejo, G. Camejo, H. Peilot, K. Oorni, and P. Kovanen Circ Res 89 2001 298 304
189. M. Murakami, and I. Kudo Curr Opin Lipidol 14 2003 431 436
190. N.R. Webb, M.A. Bostrom, S.J. Szilvassy, D.R. van der Westhuyzen, A. Daugherty, and F.C. De Beer Arterioscler Thromb Vasc Biol 23 2003 263 268
191. N.R. Webb Curr Opin Lipidol 16 2005 341 344
192. S.A. Ghesquiere, M.J. Gijbels, M. Anthonsen, P.J. van Gorp, I. van der Made, and B. Johansen J Lipid Res 46 2005 201 210
193. K. Oorni, and P.T. Kovanen Curr Opin Lipidol 20 2009 421 427
194. R.S. Rosenson Cardiovasc Drugs Ther 23 2009 93 101
195. R.S. Rosenson, C. Hislop, D. McConnell, M. Elliott, Y. Stasiv, and N. Wang Lancet 373 2009 649 658
196. K. Kugiyama, Y. Ota, K. Takazoe, Y. Moriyama, H. Kawano, and Y. Miyao Circulation 100 1999 1280 1284
197. Z. Mallat, P.G. Steg, J. Benessiano, M.L. Tanguy, K.A. Fox, and J.P. Collet J Am Coll Cardiol 46 2005 1249 1257
198. W. Koenig, C.Y. Vossen, Z. Mallat, H. Brenner, J. Benessiano, and D. Rothenbacher Eur Heart J 30 2009 2742 2748
199. W. Koenig, and N. Khuseyinova Cardiovasc Drugs Ther 23 2009 85 92
200. P. Sartipy, B. Johansen, K. Gasvik, and E. Hurt-Camejo Circ Res 86 2000 707 714
201. M.A. Bostrom, B.B. Boyanovsky, C.T. Jordan, M.P. Wadsworth, D.J. Taatjes, and F.C. de Beer Arterioscler Thromb Vasc Biol 27 2007 600 606
202. B.B. Boyanovsky, D.R. van der Westhuyzen, and N.R. Webb J Biol Chem 280 2005 32746 32752
203. B. Rosengren, H. Peilot, M. Umaerus, A.C. Jonsson-Rylander, L. Mattsson-Hulten, and C. Hallberg Arterioscler Thromb Vasc Biol 26 2006 1579 1585
204. B.B. Boyanovsky, P. Shridas, M. Simons, D.R. van der Westhuyzen, and N.R. Webb J Lipid Res 50 2009 641 650
205. B.B. Boyanovsky, X. Li, P. Shridas, M. Sunkara, A.J. Morris, and N.R. Webb Cytokine 50 2010 50 57
206. D. de Beer, E. Joubert, J. Marais, and M. Manley J Agric Food Chem 54 2006 2897 2905
207. B. Boyanovsky, M. Zack, K. Forrest, and N.R. Webb Arterioscler Thromb Vasc Biol 29 2009 532 538
208. D.K. Singh, and P.V. Subbaiah J Lipid Res 48 2007 683 692
209. Zack M, Boyanovsky BB, Shridas P, Bailey W, Forrest K, Howatt DA, et al. Atherosclerosis 2010.
210. P. Shridas, W.M. Bailey, F. Gizard, R.C. Oslund, M.H. Gelb, and D. Bruemmer Arterioscler Thromb Vasc Biol 30 2010 2014 2021
211. S. Gora, C. Perret, I. Jemel, V. Nicaud, G. Lambeau, and F. Cambien J Mol Med 87 2009 723 733
212. D. Fujioka, Y. Saito, T. Kobayashi, T. Yano, H. Tezuka, and Y. Ishimoto Circulation 117 2008 2977 2985
213. N. Degousee, F. Ghomashchi, E. Stefanski, A. Singer, B.P. Smart, and N. Borregaard J Biol Chem 277 2002 5061 5073
214. M. Kimura-Matsumoto, Y. Ishikawa, K. Komiyama, T. Tsuruta, M. Murakami, and S. Masuda Atherosclerosis 196 2008 81 91
215. Z. Shaposhnik, X. Wang, J. Trias, H. Fraser, and A.J. Lusis J Lipid Res 50 2009 623 629
216. M. Karakas, and W. Koenig IDrugs 12 2009 585 592
217. H. Fraser, C. Hislop, R.M. Christie, H.L. Rick, C.A. Reidy, and M.L. Chouinard J Cardiovasc Pharmacol 53 2009 60 65
218. J.O. Leite, U. Vaishnav, M. Puglisi, H. Fraser, J. Trias, and M.L. Fernandez BMC Cardiovasc Disord 9 2009 7
219. P.T. Wootton, N.L. Arora, F. Drenos, S.R. Thompson, J.A. Cooper, and J.W. Stephens Hum Mol Genet 16 2007 1437 1444
220. C. Pettersson, L. Fogelstrand, B. Rosengren, S. Stahlman, E. Hurt-Camejo, and B. Fagerberg J Intern Med 264 2008 155 165
221. P. Shridas, W.M. Bailey, B.B. Boyanovsky, R.C. Oslund, M.H. Gelb, and N.R. Webb J Biol Chem 285 2010 20031 20039
222. X. Li, P. Shridas, K. Forrest, W. Bailey, and N.R. Webb FASEB J 2010
223. R.J. Fijneman, L.K. Bade, J.R. Peham, M.A. van de Wiel, V.W. van Hinsbergh, and G.A. Meijer Cell Oncol 31 2009 345 356
224. R.T. Cormier, K.H. Hong, R.B. Halberg, T.L. Hawkins, P. Richardson, and R. Mulherkar Nat Genet 17 1997 88 91
225. A. Papanikolaou, Q.S. Wang, R. Mulherkar, A. Bolt, and D.W. Rosenberg Carcinogenesis 21 2000 133 138
226. S.Y. Leung, X. Chen, K.M. Chu, S.T. Yuen, J. Mathy, and J. Ji Proc Natl Acad Sci USA 99 2002 16203 16208
227. M. Sonoshita, K. Takaku, N. Sasaki, Y. Sugimoto, F. Ushikubi, and S. Narumiya Nat Med 7 2001 1048 1051
228. M. Nakanishi, D.C. Montrose, P. Clark, P.R. Nambiar, G.S. Belinsky, and K.P. Claffey Cancer Res 68 2008 3251 3259
229. J.M. Park, Y. Kanaoka, N. Eguchi, K. Aritake, S. Grujic, and A.M. Materi Cancer Res 67 2007 881 889
230. T. Murata, M.I. Lin, K. Aritake, S. Matsumoto, S. Narumiya, and H. Ozaki Proc Natl Acad Sci USA 105 2008 20009 20014
231. Q. Dong, M. Patel, K.F. Scott, G.G. Graham, P.J. Russell, and P. Sved Cancer Lett 240 2006 9 16
232. T. Mirtti, V.J. Laine, H. Hiekkanen, S. Hurme, O. Rowe, and T.J. Nevalainen APMIS 117 2009 151 161
233. A. Aggarwal, D.L. Guo, Y. Hoshida, S.T. Yuen, K.M. Chu, and S. So Cancer Res 66 2006 232 241
234. R. Mulherkar, B.M. Kirtane, A. Ramchandani, N.P. Mansukhani, S. Kannan, and K.N. Naresh Oncogene 22 2003 1936 1944
235. A. Osterstrom, J. Dimberg, K. Fransen, and P. Soderkvist Cancer Lett 182 2002 175 182
236. L.I. Eerola, F. Surrel, T.J. Nevalainen, M.H. Gelb, G. Lambeau, and V.J. Laine Biochim Biophys Acta 1761 2006 745 756
237. C.M. Mounier, D. Wendum, E. Greenspan, J.F. Flejou, D.W. Rosenberg, and G. Lambeau Br J Cancer 98 2008 587 595
238. K. Takaku, M. Sonoshita, N. Sasaki, N. Uozumi, Y. Doi, and T. Shimizu J Biol Chem 275 2000 34013 34016
239. Y. Morioka, M. Ikeda, A. Saiga, N. Fujii, Y. Ishimoto, and H. Arita FEBS Lett 487 2000 262 266
240. B. Hoeft, J. Linseisen, L. Beckmann, K. Muller-Decker, F. Canzian, and A. Husing Carcinogenesis 31 2010 466 472
241. K. Takayama, S. Hara, I. Kudo, and K. Inoue Biochem Biophys Res Commun 178 1991 1505 1511
242. M. Kallajoki, K.A. Alanen, M. Nevalainen, and T.J. Nevalainen Prostate 35 1998 263 272
243. S. Masuda, M. Murakami, S. Matsumoto, N. Eguchi, Y. Urade, and G. Lambeau Biochim Biophys Acta 1686 2004 61 76
244. S. Meizel Biol Rev Camb Philos Soc 59 1984 125 157
245. A.D. Fleming, R. Yanagimachi, and H. Yanagimachi J Reprod Fertil 63 1981 509 514
246. S. Ronkko Comp Biochem Physiol B Biochem Mol Biol 110 1995 503 509
247. M. Riffo, E. Gomez Lahoz, and P. Esponda Histochemistry 97 1992 25 31
248. M.S. Riffo, and M. Parraga J Exp Zool 275 1996 459 468
249. M. Elliott, and J.A. Higgins Cell Biol Int Rep 7 1983 1091 1096
250. R. Yanagimachi, Y. Kamiguchi, K. Mikamo, F. Suzuki, and H. Yanagimachi Am J Anat 172 1985 317 330
251. B.K. Davis, R. Byrne, and K. Bedigian Proc Natl Acad Sci USA 77 1980 1546 1550
252. A. Matsuzawa, M. Murakami, G. Atsumi, K. Imai, P. Prados, and K. Inoue Biochem J 318 Pt 2 1996 701 709
253. N. Fox, M. Song, J. Schrementi, J.D. Sharp, D.L. White, and D.W. Snyder Eur J Pharmacol 308 1996 195 203
254. J. Escoffier, I. Jemel, A. Tanemoto, Y. Taketomi, C. Payre, and C. Coatrieux J Clin Invest 120 2010 1415 1428
255. H. Sato, Y. Taketomi, Y. Isogai, Y. Miki, K. Yamamoto, and S. Masuda J Clin Invest 120 2010 1400 1414
256. H. Rejraji, B. Sion, G. Prensier, M. Carreras, C. Motta, and J.M. Frenoux Biol Reprod 74 2006 1104 1113
257. A. Lenzi, M. Picardo, L. Gandini, and F. Dondero Hum Reprod Update 2 1996 246 256
258. A. Furimsky, N. Vuong, H. Xu, P. Kumarathasan, M. Xu, and W. Weerachatyanukul Biol Reprod 72 2005 574 583
259. Y. Aksoy, H. Aksoy, K. Altinkaynak, H.R. Aydin, and A. Ozkan Prostaglandins Leukot Essent Fatty Acids 75 2006 75 79
260. K.A. Fischer, K. Van Leyen, K.W. Lovercamp, G. Manandhar, M. Sutovsky, and D. Feng Reproduction 130 2005 213 222
261. U. Haas, M. Podda, M. Behne, S. Gurrieri, A. Alonso, and G. Furstenberger J Invest Dermatol 124 2005 204 211
262. A. Schadow, K. Scholz-Pedretti, G. Lambeau, M.H. Gelb, G. Furstenberger, and J. Pfeilschifter J Invest Dermatol 116 2001 31 39
263. K.E. Rys-Sikora, A.P. Pentland, and R.L. Konger J Invest Dermatol 120 2003 86 95
264. S. Masuda, K. Yamamoto, T. Hirabayashi, Y. Ishikawa, T. Ishii, and I. Kudo Biochem J 409 2008 429 438
265. I. Munoz-Sanjuan, and A.H. Brivanlou Mol Cell Biol 25 2005 3608 3619
266. G. Lambeau, and M. Lazdunski Trends Pharmacol Sci 20 1999 162 170
267. E. Valentin, and G. Lambeau Biochim Biophys Acta 1488 2000 59 70
268. C.M. Mounier, C. Bon, and R.M. Kini Haemostasis 31 2001 279 287
269. K. Hanasaki, and H. Arita Prostaglandins Other Lipid Mediat 68-69 2002 71 82
270. S. Lizano, G. Domont, and J. Perales Toxicon 42 2003 963 977
271. M. Triggiani, F. Granata, G. Giannattasio, and G. Marone J Allergy Clin Immunol 116 2005 1000 1006
272. J. Pungercar, and I. Krizaj Toxicon 50 2007 871 892
273. D. Fujisawa, Y. Yamazaki, B. Lomonte, and T. Morita Biochem J 411 2008 515 522
274. J. Saegusa, N. Akakura, C.Y. Wu, C. Hoogland, Z. Ma, and K.S. Lam J Biol Chem 283 2008 26107 26115
275. M. Cintra-Francischinelli, P. Pizzo, L. Rodrigues-Simioni, L.A. Ponce-Soto, O. Rossetto, and B. Lomonte Cell Mol Life Sci 66 2009 1718 1728
276. E. Boilard, S.G. Bourgoin, C. Bernatchez, and M.E. Surette Blood 102 2003 2901 2909
277. K. Hanasaki, Y. Yokota, J. Ishizaki, T. Itoh, and H. Arita J Biol Chem 272 1997 32792 32797
278. A.B. Fisher, C. Dodia, A. Chander, M.F. Beers, and S.R. Bates Biochim Biophys Acta 1211 1994 256 262
279. K. Okumura, A. Ohno, M. Nishida, K. Hayashi, K. Ikeda, and S. Inoue J Biol Chem 280 2005 37651 37659
280. M. Rouault, C. Le Calvez, E. Boilard, F. Surrel, A. Singer, and F. Ghomashchi Biochemistry 46 2007 1647 1662
281. Y. Yokota, M. Notoya, K. Higashino, Y. Ishimoto, K. Nakano, and H. Arita FEBS Lett 509 2001 250 254
282. E. Zvaritch, G. Lambeau, and M. Lazdunski J Biol Chem 271 1996 250 257
283. A. Augert, C. Payre, Y. de Launoit, J. Gil, G. Lambeau, and D. Bernard EMBO Rep 10 2009 271 277
284. L.H. Beck Jr., R.G. Bonegio, G. Lambeau, D.M. Beck, D.W. Powell, and T.D. Cummins N Engl J Med 361 2009 11 21
285. H.J. Kim, K.S. Kim, S.H. Kim, S.H. Baek, H.Y. Kim, and C. Lee J Gerontol A Biol Sci Med Sci 64 2009 351 362
286. A. Miyake, H. Yamamoto, E. Kubota, K. Hamaguchi, A. Kouda, and K. Honda Br J Pharmacol 110 1993 447 453
287. R.C. Oslund, N. Cermak, C.L. Verlinde, and M.H. Gelb Bioorg Med Chem Lett 18 2008 5415 5419
288. R.D. Dillard, N.J. Bach, S.E. Draheim, D.R. Berry, D.G. Carlson, and N.Y. Chirgadze J Med Chem 39 1996 5119 5136
289. S.E. Draheim, N.J. Bach, R.D. Dillard, D.R. Berry, D.G. Carlson, and N.Y. Chirgadze J Med Chem 39 1996 5159 5175
290. R.D. Dillard, N.J. Bach, S.E. Draheim, D.R. Berry, D.G. Carlson, and N.Y. Chirgadze J Med Chem 39 1996 5137 5158
291. D.L. Scott, S.P. White, J.L. Browning, J.J. Rosa, M.H. Gelb, and P.B. Sigler Science 254 1991 1007 1010
292. D.L. Bowton, A.A. Dmitrienko, E. Israel, B.G. Zeiher, and G.D. Sides J Asthma 42 2005 65 71
293. B.G. Zeiher, J. Steingrub, P.F. Laterre, A. Dmitrienko, Y. Fukiishi, and E. Abraham Crit Care Med 33 2005 1741 1748
294. M. Ghosh, R. Loper, F. Ghomashchi, D.E. Tucker, J.V. Bonventre, and M.H. Gelb J Biol Chem 282 2007 11676 11686
295. A. Dessen, J. Tang, H. Schmidt, M. Stahl, J.D. Clark, and J. Seehra Cell 97 1999 349 360
296. O. Perisic, S. Fong, D.E. Lynch, M. Bycroft, and R.L. Williams J Biol Chem 273 1998 1596 1604
297. G.Y. Xu, T. McDonagh, H.A. Yu, E.A. Nalefski, J.D. Clark, and D.A. Cumming J Mol Biol 280 1998 485 500
298. J.D. Clark, L.L. Lin, R.W. Kriz, C.S. Ramesha, L.A. Sultzman, and A.Y. Lin Cell 65 1991 1043 1051
299. L.L. Lin, M. Wartmann, A.Y. Lin, J.L. Knopf, A. Seth, and R.J. Davis Cell 72 1993 269 278
300. R.V. Stahelin, J.D. Rafter, S. Das, and W. Cho J Biol Chem 278 2003 12452 12460
301. M. Murakami, S. Das, Y.J. Kim, W. Cho, and L. Kudo FEBS Lett 546 2003 251 256
302. J.H. Evans, and C.C. Leslie J Biol Chem 279 2004 6005 6016
303. T. Hirabayashi, K. Kume, K. Hirose, T. Yokomizo, M. Iino, and H. Itoh J Biol Chem 274 1999 5163 5169
304. S. Das, J.D. Rafter, K.P. Kim, S.P. Gygi, and W. Cho J Biol Chem 278 2003 41431 41442
305. Y. Hefner, A.G. Borsch-Haubold, M. Murakami, J.I. Wilde, S. Pasquet, and D. Schieltz J Biol Chem 275 2000 37542 37551
306. W. Tian, G.T. Wijewickrama, J.H. Kim, S. Das, M.P. Tun, and N. Gokhale J Biol Chem 283 2008 3960 3971
307. M.M. Muthalif, Y. Hefner, S. Canaan, J. Harper, H. Zhou, and J.H. Parmentier J Biol Chem 276 2001 39653 39660
308. Z. Pavicevic, C.C. Leslie, and K.U. Malik J Lipid Res 49 2008 724 737
309. M. Mosior, D.A. Six, and E.A. Dennis J Biol Chem 273 1998 2184 2191
310. J. Balsinde, M.A. Balboa, W.H. Li, J. Llopis, and E.A. Dennis J Immunol 164 2000 5398 5402
311. S. Das, and W. Cho J Biol Chem 277 2002 23838 23846
312. J.H. Evans, D. Murray, C.C. Leslie, and J.J. Falke Mol Biol Cell 17 2006 56 66
313. J. Casas, M.A. Gijon, A.G. Vigo, M.S. Crespo, J. Balsinde, and M.A. Balboa Mol Biol Cell 17 2006 155 162
314. D.E. Tucker, M. Ghosh, F. Ghomashchi, R. Loper, S. Suram, and B.S. John J Biol Chem 284 2009 9596 9611
315. P. Subramanian, R.V. Stahelin, Z. Szulc, A. Bielawska, W. Cho, and C.E. Chalfant J Biol Chem 280 2005 17601 17607
316. R.V. Stahelin, P. Subramanian, M. Vora, W. Cho, and C.E. Chalfant J Biol Chem 282 2007 20467 20474
317. N.F. Lamour, P. Subramanian, D.S. Wijesinghe, R.V. Stahelin, J.V. Bonventre, and C.E. Chalfant J Biol Chem 284 2009 26897 26907
318. C. Graf, B. Zemann, P. Rovina, N. Urtz, A. Schanzer, and R. Reuschel J Immunol 180 2008 3457 3466
319. J.V. Bonventre, Z. Huang, M.R. Taheri, E. O'Leary, E. Li, and M.A. Moskowitz Nature 390 1997 622 625
320. H. Fujishima, R.O. Sanchez Mejia, C.O. Bingham 3rd, B.K. Lam, A. Sapirstein, and J.V. Bonventre Proc Natl Acad Sci USA 96 1999 4803 4807
321. N. Nakatani, N. Uozumi, K. Kume, M. Murakami, I. Kudo, and T. Shimizu Biochem J 352 Pt 2 2000 311 317
322. N. Uozumi, Y. Kita, and T. Shimizu J Immunol 181 2008 3558 3566
323. T. Nagase, N. Uozumi, S. Ishii, K. Kume, T. Izumi, and Y. Ouchi Nat Immunol 1 2000 42 46
324. T. Nagase, N. Uozumi, S. Ishii, Y. Kita, H. Yamamoto, and E. Ohga Nat Med 8 2002 480 484
325. B.B. Rubin, G.P. Downey, A. Koh, N. Degousee, F. Ghomashchi, and L. Nallan J Biol Chem 280 2005 7519 7529
326. C. Yao, D. Sakata, Y. Esaki, Y. Li, T. Matsuoka, and K. Kuroiwa Nat Med 15 2009 633 640
327. Y. Kihara, T. Matsushita, Y. Kita, S. Uematsu, S. Akira, and J. Kira Proc Natl Acad Sci USA 106 2009 21807 21812
328. Y. Kihara, T. Yokomizo, A. Kunita, Y. Morishita, M. Fukayama, and S. Ishii Biochem Biophys Res Commun 394 2010 673 678
329. Y. Kihara, K. Yanagida, K. Masago, Y. Kita, D. Hishikawa, and H. Shindou J Immunol 181 2008 5008 5014
330. A. Kalyvas, and S. David Neuron 41 2004 323 335
331. S. Marusic, M.W. Leach, J.W. Pelker, M.L. Azoitei, N. Uozumi, and J. Cui J Exp Med 202 2005 841 851
332. M. Hegen, L. Sun, N. Uozumi, K. Kume, M.E. Goad, and C.L. Nickerson-Nutter J Exp Med 197 2003 1297 1302
333. C. Miyaura, M. Inada, C. Matsumoto, T. Ohshiba, N. Uozumi, and T. Shimizu J Exp Med 197 2003 1303 1310
334. K. Kishimoto, K. Matsumura, Y. Kataoka, H. Morii, and Y. Watanabe Neuroscience 92 1999 1061 1077
335. T.D. Le, Y. Shirai, T. Okamoto, T. Tatsukawa, S. Nagao, and T. Shimizu Proc Natl Acad Sci USA 107 2010 3198 3203
336. P. Klivenyi, M.F. Beal, R.J. Ferrante, O.A. Andreassen, M. Wermer, and M.R. Chin J Neurochem 71 1998 2634 2637
337. B. Kriem, I. Sponne, A. Fifre, C. Malaplate-Armand, K. Lozac'h-Pillot, and V. Koziel FASEB J 19 2005 85 87
338. R.O. Sanchez-Mejia, J.W. Newman, S. Toh, G.Q. Yu, Y. Zhou, and B. Halabisky Nat Neurosci 11 2008 1311 1318
339. C. Iadecola, K. Niwa, S. Nogawa, X. Zhao, M. Nagayama, and E. Araki Proc Natl Acad Sci USA 98 2001 1294 1299
340. T. Hoshino, T. Namba, M. Takehara, T. Nakaya, Y. Sugimoto, and W. Araki J Biol Chem 284 2009 18493 18502
341. M. Oshima, J.E. Dinchuk, S.L. Kargman, H. Oshima, B. Hancock, and E. Kwong Cell 87 1996 803 809
342. K.H. Hong, J.C. Bonventre, E. O'Leary, J.V. Bonventre, and E.S. Lander Proc Natl Acad Sci USA 98 2001 3935 3939
343. M.C. Weiser-Evans, X.Q. Wang, J. Amin, V. Van Putten, R. Choudhary, and R.A. Winn Cancer Res 69 2009 1733 1738
344. M.I. Patel, J. Singh, M. Niknami, C. Kurek, M. Yao, and S. Lu Clin Cancer Res 14 2008 8070 8079
345. M. Dong, K. Guda, P.R. Nambiar, A. Rezaie, G.S. Belinsky, and G. Lambeau Carcinogenesis 24 2003 307 315
346. G.A. Gross, T. Imamura, C. Luedke, S.K. Vogt, L.M. Olson, and D.M. Nelson Proc Natl Acad Sci USA 95 1998 11875 11879
347. Y. Sugimoto, A. Yamasaki, E. Segi, K. Tsuboi, Y. Aze, and T. Nishimura Science 277 1997 681 683
348. H. Song, H. Lim, B.C. Paria, H. Matsumoto, L.L. Swift, and J. Morrow Development 129 2002 2879 2889
349. H. Lim, B.C. Paria, S.K. Das, J.E. Dinchuk, R. Langenbach, and J.M. Trzaskos Cell 91 1997 197 208
350. H. Hizaki, E. Segi, Y. Sugimoto, M. Hirose, T. Saji, and F. Ushikubi Proc Natl Acad Sci USA 96 1999 10501 10506
351. C.R. Kennedy, Y. Zhang, S. Brandon, Y. Guan, K. Coffee, and C.D. Funk Nat Med 5 1999 217 220
352. X. Ye, K. Hama, J.J. Contos, B. Anliker, A. Inoue, and M.K. Skinner Nature 435 2005 104 108
353. D.A. Wong, Y. Kita, N. Uozumi, and T. Shimizu J Exp Med 196 2002 349 357
354. D.H. Adler, J.D. Cogan, J.A. Phillips 3rd, N. Schnetz-Boutaud, G.L. Milne, and T. Iverson J Clin Invest 118 2008 2121 2131
355. K. Takeuchi, H. Ukawa, S. Kato, O. Furukawa, H. Araki, and Y. Sugimoto Gastroenterology 117 1999 1128 1135
356. P. Downey, A. Sapirstein, E. O'Leary, T.X. Sun, D. Brown, and J.V. Bonventre Am J Physiol Renal Physiol 280 2001 F607 F618
357. S. Haq, H. Kilter, A. Michael, J. Tao, E. O'Leary, and X.M. Sun Nat Med 9 2003 944 951
358. E. Regan-Klapisz, V. Krouwer, M. Langelaar-Makkinje, L. Nallan, M. Gelb, and H. Gerritsen Mol Biol Cell 20 2009 4225 4234
359. M. Mashimo, T. Hirabayashi, T. Murayama, and T. Shimizu J Cell Sci 121 2008 3015 3024
360. E. San Pietro, M. Capestrano, E.V. Polishchuk, A. DiPentima, A. Trucco, and P. Zizza PLoS Biol 7 2009 e1000194
361. M. Girotti, J.H. Evans, D. Burke, and C.C. Leslie J Biol Chem 279 2004 19113 19121
362. Z. Shmelzer, N. Haddad, E. Admon, I. Pessach, T.L. Leto, and Z. Eitan-Hazan J Cell Biol 162 2003 683 692
363. S.B. Gaudreault, C. Chabot, J.P. Gratton, and J. Poirier J Biol Chem 279 2004 356 362
364. S. Tashiro, T. Sumi, N. Uozumi, T. Shimizu, and T. Nakamura J Biol Chem 279 2004 17715 17722
365. Y. Nakatani, T. Tanioka, S. Sunaga, M. Murakami, and I. Kudo J Biol Chem 275 2000 1161 1168
366. A.M. Sheridan, T. Force, H.J. Yoon, E. O'Leary, G. Choukroun, and M.R. Taheri Mol Cell Biol 21 2001 4470 4481
367. G. Atsumi, M. Murakami, K. Kojima, A. Hadano, M. Tajima, and I. Kudo J Biol Chem 275 2000 18248 18258
368. G. Atsumi, M. Tajima, A. Hadano, Y. Nakatani, M. Murakami, and I. Kudo J Biol Chem 273 1998 13870 13877
369. A. Gubern, J. Casas, M. Barcelo-Torns, D. Barneda, X. de la Rosa, and R. Masgrau J Biol Chem 283 2008 27369 27382
370. H. Ii, S. Hatakeyama, K. Tsutsumi, T. Sato, and S. Akiba Prostaglandins Other Lipid Mediat 86 2008 12 17
371. H. Ii, N. Yokoyama, S. Yoshida, K. Tsutsumi, S. Hatakeyama, and T. Sato PLoS One 4 2009 e8089
372. H. Ii, M. Oka, A. Yamashita, K. Waku, N. Uozumi, and T. Shimizu Biol Pharm Bull 31 2008 6 12
373. T. Ohto, N. Uozumi, T. Hirabayashi, and T. Shimizu J Biol Chem 280 2005 24576 24583
374. C. Song, X.J. Chang, K.M. Bean, M.S. Proia, J.L. Knopf, and R.W. Kriz J Biol Chem 274 1999 17063 17067
375. F. Ghomashchi, G.S. Naika, J.G. Bollinger, A. Aloulou, M. Lehr, and C.C. Leslie J Biol Chem 2010
376. M. Ghosh, R. Loper, M.H. Gelb, and C.C. Leslie J Biol Chem 281 2006 16615 16624
377. H. Chiba, H. Michibata, K. Wakimoto, M. Seishima, S. Kawasaki, and K. Okubo J Biol Chem 279 2004 12890 12897
378. K.W. Underwood, C. Song, R.W. Kriz, X.J. Chang, J.L. Knopf, and L.L. Lin J Biol Chem 273 1998 21926 21932
379. C.M. Jenkins, X. Han, J. Yang, D.J. Mancuso, H.F. Sims, and A.J. Muslin Biochemistry 42 2003 11798 11807
380. D.E. Tucker, A. Stewart, L. Nallan, P. Bendale, F. Ghomashchi, and M.H. Gelb J Lipid Res 46 2005 2122 2133
381. A. Yamashita, R. Kamata, N. Kawagishi, H. Nakanishi, H. Suzuki, and T. Sugiura J Biochem 137 2005 557 567
382. K. Asai, T. Hirabayashi, T. Houjou, N. Uozumi, R. Taguchi, and T. Shimizu J Biol Chem 278 2003 8809 8814
383. M. Murakami, S. Masuda, and I. Kudo Biochem J 372 2003 695 702
384. A. Vitale, J. Perlin, L. Leonelli, J. Herr, P. Wright, and L. Digilio Dev Biol 282 2005 374 384
385. I.P. Street, H.K. Lin, F. Laliberte, F. Ghomashchi, Z. Wang, and H. Perrier Biochemistry 32 1993 5935 5940
386. T. Nagase, N. Uozumi, T. Aoki-Nagase, K. Terawaki, S. Ishii, and T. Tomita Am J Physiol Lung Cell Mol Physiol 284 2003 L720 L726
387. R. Malaviya, J. Ansell, L. Hall, M. Fahmy, R.L. Argentieri, and G.C. Olini Jr. Eur J Pharmacol 539 2006 195 204
388. S.T. Reddy, and H.R. Herschman J Biol Chem 272 1997 3231 3237
389. E.J. Ackermann, K. Conde-Frieboes, and E.A. Dennis J Biol Chem 270 1995 445 450
390. J. Balsinde, M.A. Balboa, P.A. Insel, and E.A. Dennis Annu Rev Pharmacol Toxicol 39 1999 175 189
391. K. Seno, T. Okuno, K. Nishi, Y. Murakami, F. Watanabe, and T. Matsuura J Med Chem 43 2000 1041 1044
392. M. Lehr, M. Klimt, and A.S. Elfringhoff Bioorg Med Chem Lett 11 2001 2569 2572
393. K. Griessbach, M. Klimt, A. Schulze Elfringhoff, and M. Lehr Arch Pharm (Weinheim) 335 2002 547 555
394. J. Ludwig, S. Bovens, C. Brauch, A.S. Elfringhoff, and M. Lehr J Med Chem 49 2006 2611 2620
395. S. Connolly, C. Bennion, S. Botterell, P.J. Croshaw, C. Hallam, and K. Hardy J Med Chem 45 2002 1348 1362
396. G. Kokotos, S. Kotsovolou, D.A. Six, V. Constantinou-Kokotou, C.C. Beltzner, and E.A. Dennis J Med Chem 45 2002 2891 2893
397. G. Kokotos, D.A. Six, V. Loukas, T. Smith, V. Constantinou-Kokotou, and D. Hadjipavlou-Litina J Med Chem 47 2004 3615 3628
398. K.L. Lee, M.A. Foley, L. Chen, M.L. Behnke, F.E. Lovering, and S.J. Kirincich J Med Chem 50 2007 1380 1400
399. K.L. Lee, M.L. Behnke, M.A. Foley, L. Chen, W. Wang, and R. Vargas Bioorg Med Chem 16 2008 1345 1358
400. J.C. McKew, K.L. Lee, M.W. Shen, P. Thakker, M.A. Foley, and M.L. Behnke J Med Chem 51 2008 3388 3413
401. T.J. Rydel, J.M. Williams, E. Krieger, F. Moshiri, W.C. Stallings, and S.M. Brown Biochemistry 42 2003 6696 6708
402. J. Tang, R.W. Kriz, N. Wolfman, M. Shaffer, J. Seehra, and S.S. Jones J Biol Chem 272 1997 8567 8575
403. M.A. Balboa, J. Balsinde, S.S. Jones, and E.A. Dennis J Biol Chem 272 1997 8576 8580
404. P.K. Larsson, H.E. Claesson, and B.P. Kennedy J Biol Chem 273 1998 207 214
405. Z. Ma, X. Wang, W. Nowatzke, S. Ramanadham, and J. Turk J Biol Chem 274 1999 9607 9616
406. P.K. Larsson Forsell, B.P. Kennedy, and H.E. Claesson Eur J Biochem 262 1999 575 585
407. Y.C. Lio, and E.A. Dennis Biochim Biophys Acta 1392 1998 320 332
408. Y.H. Hsu, J.E. Burke, S. Li, V.L. Woods Jr., and E.A. Dennis J Biol Chem 284 2009 23652 23661
409. J. Balsinde, M.A. Balboa, and E.A. Dennis J Biol Chem 272 1997 29317 29321
410. I. Baburina, and S. Jackowski J Biol Chem 274 1999 9400 9408
411. S. Ramanadham, F.F. Hsu, A. Bohrer, Z. Ma, and J. Turk J Biol Chem 274 1999 13915 13927
412. Z. Ma, S. Ramanadham, M. Wohltmann, A. Bohrer, F.F. Hsu, and J. Turk J Biol Chem 276 2001 13198 13208
413. S. Akiba, S. Mizunaga, K. Kume, M. Hayama, and T. Sato J Biol Chem 274 1999 19906 19912
414. Z. Wang, S. Ramanadham, Z.A. Ma, S. Bao, D.J. Mancuso, and R.W. Gross J Biol Chem 280 2005 6840 6849
415. C.M. Jenkins, M.J. Wolf, D.J. Mancuso, and R.W. Gross J Biol Chem 276 2001 7129 7135
416. T. Smani, S.I. Zakharov, E. Leno, P. Csutora, E.S. Trepakova, and V.M. Bolotina J Biol Chem 278 2003 11909 11915
417. P. Csutora, V. Zarayskiy, K. Peter, F. Monje, T. Smani, and S.I. Zakharov J Biol Chem 281 2006 34926 34935
418. T. Smani, S.I. Zakharov, P. Csutora, E. Leno, E.S. Trepakova, and V.M. Bolotina Nat Cell Biol 6 2004 113 120
419. C.M. Jenkins, W. Yan, D.J. Mancuso, and R.W. Gross J Biol Chem 281 2006 15615 15624
420. V.M. Bolotina J Physiol 586 2008 3035 3042
421. M. Vig, C. Peinelt, A. Beck, D.L. Koomoa, D. Rabah, and M. Koblan-Huberson Science 312 2006 1220 1223
422. F. Vanden Abeele, A. Zholos, G. Bidaux, Y. Shuba, S. Thebault, and B. Beck J Biol Chem 281 2006 40174 40182
423. D.A. Andersson, M. Nash, and S. Bevan J Neurosci 27 2007 3347 3355
424. S. Bao, D.J. Miller, Z. Ma, M. Wohltmann, G. Eng, and S. Ramanadham J Biol Chem 279 2004 38194 38200
425. W.C. Chang, and A.B. Parekh J Biol Chem 279 2004 29994 29999
426. S.H. Moon, C.M. Jenkins, D.J. Mancuso, J. Turk, and R.W. Gross J Biol Chem 283 2008 33975 33987
427. D.M. Nikolic, M.C. Gong, J. Turk, and S.R. Post J Biol Chem 282 2007 33405 33411
428. E.L. Riddle, B.K. Rana, K.K. Murthy, F. Rao, E. Eskin, and D.T. O'Connor Hypertension 47 2006 415 420
429. Z. Xie, M.C. Gong, W. Su, J. Turk, and Z. Guo J Biol Chem 282 2007 25278 25289
430. Z. Xie, M.C. Gong, W. Su, D. Xie, J. Turk, and Z. Guo J Biol Chem 285 2010 8628 8638
431. H.H. Dietrich, D.R. Abendschein, S.H. Moon, N. Nayeb-Hashemi, D.J. Mancuso, and C.M. Jenkins Am J Physiol Heart Circ Physiol 298 2010 H2208 H2220
432. J. Sharma, J. Turk, and J. McHowat Biochemistry 49 2010 5473 5481
433. S. Bao, H. Song, M. Wohltmann, S. Ramanadham, W. Jin, and A. Bohrer J Biol Chem 281 2006 20958 20973
434. S. Bao, A. Bohrer, S. Ramanadham, W. Jin, S. Zhang, and J. Turk J Biol Chem 281 2006 187 198
435. S. Bao, D.A. Jacobson, M. Wohltmann, A. Bohrer, W. Jin, and L.H. Philipson Am J Physiol Endocrinol Metab 294 2008 E217 E229
436. D.J. Mancuso, D.R. Abendschein, C.M. Jenkins, X. Han, J.E. Saffitz, and R.B. Schuessler J Biol Chem 278 2003 22231 22236
437. S. Ramanadham, K.E. Yarasheski, M.J. Silva, M. Wohltmann, D.V. Novack, and B. Christiansen Am J Pathol 172 2008 868 881
438. A. Gubern, M. Barcelo-Torns, J. Casas, D. Barneda, R. Masgrau, and F. Picatoste J Biol Chem 284 2009 5697 5708
439. A.K. Roshak, E.A. Capper, C. Stevenson, C. Eichman, and L.A. Marshall J Biol Chem 275 2000 35692 35698
440. J.M. Moran, R.M. Buller, J. McHowat, J. Turk, M. Wohltmann, and R.W. Gross J Biol Chem 280 2005 28162 28168
441. S.H. Lee, D.W. Park, S.C. Park, Y.K. Park, S.Y. Hong, and J.R. Kim J Immunol 183 2009 7497 7504
442. S. Ayilavarapu, A. Kantarci, G. Fredman, O. Turkoglu, K. Omori, and H. Liu J Immunol 184 2010 1507 1515
443. R.S. Mishra, K.A. Carnevale, and M.K. Cathcart J Exp Med 205 2008 347 359
444. K. Schroder, and J. Tschopp Cell 140 2010 821 832
445. A. Piccini, S. Carta, S. Tassi, D. Lasiglie, G. Fossati, and A. Rubartelli Proc Natl Acad Sci USA 105 2008 8067 8072
446. L. Franchi, G. Chen, N. Marina-Garcia, A. Abe, Y. Qu, and S. Bao J Innate Immun 1 2009 607 617
447. K. Lauber, E. Bohn, S.M. Krober, Y.J. Xiao, S.G. Blumenthal, and R.K. Lindemann Cell 113 2003 717 730
448. K. Shinzawa, and Y. Tsujimoto J Cell Biol 163 2003 1219 1230
449. C. Peter, M. Waibel, C.G. Radu, L.V. Yang, O.N. Witte, and K. Schulze-Osthoff J Biol Chem 283 2008 5296 5305
450. O. Soehnlein, L. Lindbom, and C. Weber Blood 114 2009 4613 4623
451. S. Bao, Y. Li, X. Lei, M. Wohltmann, W. Jin, and A. Bohrer J Biol Chem 282 2007 27100 27114
452. X. Lei, S. Zhang, A. Bohrer, and S. Ramanadham J Biol Chem 283 2008 34819 34832
453. J. Nozaki, H. Kubota, H. Yoshida, M. Naitoh, J. Goji, and T. Yoshinaga Genes Cells 9 2004 261 270
454. X. Lei, S. Zhang, S.E. Barbour, A. Bohrer, E.L. Ford, and A. Koizumi J Biol Chem 285 2010 6693 6705
455. H. Li, Z. Zhao, G. Wei, L. Yan, D. Wang, and H. Zhang FASEB J 2010
456. N.V. Morgan, S.K. Westaway, J.E. Morton, A. Gregory, P. Gissen, and S. Sonek Nat Genet 38 2006 752 754
457. F. Sina, S. Shojaee, E. Elahi, and C. Paisan-Ruiz Eur J Neurol 16 2009 101 104
458. K. Shinzawa, H. Sumi, M. Ikawa, Y. Matsuoka, M. Okabe, and S. Sakoda J Neurosci 28 2008 2212 2220
459. I. Malik, J. Turk, D.J. Mancuso, L. Montier, M. Wohltmann, and D.F. Wozniak Am J Pathol 172 2008 406 416
460. H. Wada, T. Yasuda, I. Miura, K. Watabe, C. Sawa, and H. Kamijuku Am J Pathol 175 2009 2257 2263
461. R. Lopez-Vales, X. Navarro, T. Shimizu, C. Baskakis, G. Kokotos, and V. Constantinou-Kokotou Brain 131 2008 2620 2631
462. S. Bione, P. D'Adamo, E. Maestrini, A.K. Gedeon, P.A. Bolhuis, and D. Toniolo Nat Genet 12 1996 385 389
463. A. Malhotra, I. Edelman-Novemsky, Y. Xu, H. Plesken, J. Ma, and M. Schlame Proc Natl Acad Sci USA 106 2009 2337 2341
464. K. Seleznev, C. Zhao, X.H. Zhang, K. Song, and Z.A. Ma J Biol Chem 281 2006 22275 22288
465. D.J. Mancuso, C.M. Jenkins, and R.W. Gross J Biol Chem 275 2000 9937 9945
466. H. Tanaka, R. Takeya, and H. Sumimoto Biochem Biophys Res Commun 272 2000 320 326
467. D.J. Mancuso, C.M. Jenkins, H.F. Sims, J.M. Cohen, J. Yang, and R.W. Gross Eur J Biochem 271 2004 4709 4724
468. M. Murakami, S. Masuda, K. Ueda-Semmyo, E. Yoda, H. Kuwata, and Y. Takanezawa J Biol Chem 280 2005 14028 14041
469. W. Yan, C.M. Jenkins, X. Han, D.J. Mancuso, H.F. Sims, and K. Yang J Biol Chem 280 2005 26669 26679
470. D.J. Mancuso, X. Han, C.M. Jenkins, J.J. Lehman, N. Sambandam, and H.F. Sims J Biol Chem 282 2007 9216 9227
471. D.J. Mancuso, H.F. Sims, X. Han, C.M. Jenkins, S.P. Guan, and K. Yang J Biol Chem 282 2007 34611 34622
472. E. Yoda, K. Hachisu, Y. Taketomi, K. Yoshida, M. Nakamura, and K. Ikeda J Lipid Res 2010
473. H. Song, M. Wohltmann, S. Bao, J.H. Ladenson, C.F. Semenkovich, and J. Turk Am J Physiol Endocrinol Metab 298 2010 E1097 E1114
474. D.J. Mancuso, H.F. Sims, K. Yang, M.A. Kiebish, X. Su, and C.M. Jenkins J Biol Chem 285 2010 36495 36510
475. X. Su, D.J. Mancuso, P.E. Bickel, C.M. Jenkins, and R.W. Gross J Biol Chem 279 2004 21740 21748
476. D.J. Mancuso, P. Kotzbauer, D.F. Wozniak, H.F. Sims, C.M. Jenkins, and S. Guan J Biol Chem 284 2009 35632 35644
477. H. Kuwata, C. Fujimoto, E. Yoda, S. Shimbara, Y. Nakatani, and S. Hara J Biol Chem 282 2007 20124 20132
478. Y. Li, D. Dinsdale, and P. Glynn J Biol Chem 278 2003 8820 8825
479. M.K. Johnson Arch Toxicol 37 1977 113 115
480. O. Zaccheo, D. Dinsdale, P.A. Meacock, and P. Glynn J Biol Chem 279 2004 24024 24033
481. J.P. Murray, and C.R. McMaster J Biol Chem 280 2005 8544 8552
482. J.P. Fernandez-Murray, and C.R. McMaster Biochim Biophys Acta 1771 2007 331 336
483. J.P. Fernandez-Murray, G.J. Gaspard, S.A. Jesch, and C.R. McMaster J Biol Chem 284 2009 36034 36046
484. M. Muhlig-Versen, A.B. da Cruz, J.A. Tschape, M. Moser, R. Buttner, and K. Athenstaedt J Neurosci 25 2005 2865 2873
485. K. Akassoglou, B. Malester, J. Xu, L. Tessarollo, J. Rosenbluth, and M.V. Chao Proc Natl Acad Sci USA 101 2004 5075 5080
486. D.J. Read, Y. Li, M.V. Chao, J.B. Cavanagh, and P. Glynn J Neurosci 29 2009 11594 11600
487. S. Rainier, M. Bui, E. Mark, D. Thomas, D. Tokarz, and L. Ming Am J Hum Genet 82 2008 780 785
488. M. Moser, Y. Li, K. Vaupel, D. Kretzschmar, R. Kluge, and P. Glynn Mol Cell Biol 24 2004 1667 1679
489. M. Gallazzini, J.D. Ferraris, M. Kunin, R.G. Morris, and M.B. Burg Proc Natl Acad Sci USA 103 2006 15260 15265
490. R. Chen, P.A. Chang, D.X. Long, C.Y. Liu, L. Yang, and Y.J. Wu Int J Biochem Cell Biol 39 2007 124 132
491. A. Bettencourt da Cruz, J. Wentzell, and D. Kretzschmar J Neurosci 28 2008 10885 10892
492. P.C. Kienesberger, A. Lass, K. Preiss-Landl, H. Wolinski, S.D. Kohlwein, and R. Zimmermann J Biol Chem 283 2008 5908 5917
493. C.M. Jenkins, D.J. Mancuso, W. Yan, H.F. Sims, B. Gibson, and R.W. Gross J Biol Chem 279 2004 48968 48975
494. R. Zimmermann, J.G. Strauss, G. Haemmerle, G. Schoiswohl, R. Birner-Gruenberger, and M. Riederer Science 306 2004 1383 1386
495. E.E. Kershaw, J.K. Hamm, L.A. Verhagen, O. Peroni, M. Katic, and J.S. Flier Diabetes 55 2006 148 157
496. K. Jaworski, E. Sarkadi-Nagy, R.E. Duncan, M. Ahmadian, and H.S. Sul Am J Physiol Gastrointest Liver Physiol 293 2007 G1 G4
497. K.G. Soni, G.A. Mardones, R. Sougrat, E. Smirnova, C.L. Jackson, and J.S. Bonifacino J Cell Sci 122 2009 1834 1841
498. A. Lass, R. Zimmermann, G. Haemmerle, M. Riederer, G. Schoiswohl, and M. Schweiger Cell Metab 3 2006 309 319
499. M. Schweiger, G. Schoiswohl, A. Lass, F.P. Radner, G. Haemmerle, and R. Malli J Biol Chem 283 2008 17211 17220
500. A. Gruber, I. Cornaciu, A. Lass, M. Schweiger, M. Poeschl, and C. Eder J Biol Chem 285 2010 12289 12298
501. G. Montero-Moran, J.M. Caviglia, D. McMahon, A. Rothenberg, V. Subramanian, and Z. Xu J Lipid Res 51 2010 709 719
502. L. Notari, V. Baladron, J.D. Aroca-Aguilar, N. Balko, R. Heredia, and C. Meyer J Biol Chem 281 2006 38022 38037
503. C. Chung, J.A. Doll, A.K. Gattu, C. Shugrue, M. Cornwell, and P. Fitchev J Hepatol 48 2008 471 478
504. H. Miyoshi, J.W. Perfield 2nd, S.C. Souza, W.J. Shen, H.H. Zhang, and Z.S. Stancheva J Biol Chem 282 2007 996 1002
505. X. Yang, X. Lu, M. Lombes, G.B. Rha, Y.I. Chi, and T.M. Guerin Cell Metab 11 2010 194 205
506. A.K. Taggart, J. Kero, X. Gan, T.Q. Cai, K. Cheng, and M. Ippolito J Biol Chem 280 2005 26649 26652
507. K. Ahmed, S. Tunaru, C.D. Langhans, J. Hanson, C.W. Michalski, and S. Kolker J Biol Chem 284 2009 21928 21933
508. K. Ahmed, S. Tunaru, C. Tang, M. Muller, A. Gille, and A. Sassmann Cell Metab 11 2010 311 319
509. G. Haemmerle, A. Lass, R. Zimmermann, G. Gorkiewicz, C. Meyer, and J. Rozman Science 312 2006 734 737
510. E. Huijsman, C. van de Par, C. Economou, C. van der Poel, G.S. Lynch, and G. Schoiswohl Am J Physiol Endocrinol Metab 297 2009 E505 E513
511. M. Ahmadian, R.E. Duncan, K.A. Varady, D. Frasson, M.K. Hellerstein, and A.L. Birkenfeld Diabetes 58 2009 855 866
512. P.G. Chandak, B. Radovic, E. Aflaki, D. Kolb, M. Buchebner, and E. Frohlich J Biol Chem 285 2010 20192 20201
513. C. Lefevre, F. Jobard, F. Caux, B. Bouadjar, A. Karaduman, and R. Heilig Am J Hum Genet 69 2001 1002 1012
514. J. Fischer, C. Lefevre, E. Morava, J.M. Mussini, P. Laforet, and A. Negre-Salvayre Nat Genet 39 2007 28 30
515. M. Schweiger, A. Lass, R. Zimmermann, T.O. Eichmann, and R. Zechner Am J Physiol Endocrinol Metab 297 2009 E289 E296
516. V. Schoenborn, I.M. Heid, C. Vollmert, A. Lingenhel, T.D. Adams, and P.N. Hopkins Diabetes 55 2006 1270 1275
517. K. Kobayashi, T. Inoguchi, Y. Maeda, N. Nakashima, A. Kuwano, and E. Eto J Clin Endocrinol Metab 93 2008 2877 2884
518. F.P. Radner, I.E. Streith, G. Schoiswohl, M. Schweiger, M. Kumari, and T.O. Eichmann J Biol Chem 285 2010 7300 7311
519. Y.M. Liu, M. Moldes, J.P. Bastard, E. Bruckert, N. Viguerie, and B. Hainque J Clin Endocrinol Metab 89 2004 2684 2689
520. A.C. Lake, Y. Sun, J.L. Li, J.E. Kim, J.W. Johnson, and D. Li J Lipid Res 46 2005 2477 2487
521. Y. Huang, S. He, J.Z. Li, Y.K. Seo, T.F. Osborne, and J.C. Cohen Proc Natl Acad Sci USA 107 2010 7892 7897
522. S. Romeo, J. Kozlitina, C. Xing, A. Pertsemlidis, D. Cox, and L.A. Pennacchio Nat Genet 40 2008 1461 1465
523. A. Kotronen, L.E. Johansson, L.M. Johansson, C. Roos, J. Westerbacka, and A. Hamsten Diabetologia 52 2009 1056 1060
524. S. Sookoian, G.O. Castano, A.L. Burgueno, T.F. Gianotti, M.S. Rosselli, and C.J. Pirola J Lipid Res 50 2009 2111 2116
525. C. Tian, R.P. Stokowski, D. Kershenobich, D.G. Ballinger, and D.A. Hinds Nat Genet 42 2010 21 23
526. L.E. Johansson, U. Lindblad, C.A. Larsson, L. Rastam, and M. Ridderstrale Eur J Endocrinol 159 2008 577 583
527. B. Kollerits, S. Coassin, N.D. Beckmann, A. Teumer, S. Kiechl, and A. Doring Hum Mol Genet 18 2009 4669 4676
528. S. He, C. McPhaul, J.Z. Li, R. Garuti, L. Kinch, and N.V. Grishin J Biol Chem 285 2010 6706 6715
529. W. Chen, B. Chang, L. Li, and L. Chan Hepatology 52 2010 1134 1142
530. J. Gao, and M. Simon J Invest Dermatol 124 2005 1259 1266
531. J.G. Gao, A. Shih, R. Gruber, M. Schmuth, and M. Simon Mol Genet Metab 96 2009 253 260
532. J.G. Gao, and M. Simon J Invest Dermatol 126 2006 2087 2095
533. J.G. Gao, and M. Simon Biochem Biophys Res Commun 360 2007 501 506
534. L. Chen, M. Iijima, M. Tang, M.A. Landree, Y.E. Huang, and Y. Xiong Dev Cell 12 2007 603 614
535. H. Khakpour, and W.H. Frishman Cardiol Rev 17 2009 222 229
536. C.J. Packard Curr Opin Cardiol 24 2009 358 363
537. S. Tsimikas, L.D. Tsironis, and A.D. Tselepis Arterioscler Thromb Vasc Biol 27 2007 2094 2099
538. R.L. Wilensky, and C.H. Macphee Curr Opin Lipidol 20 2009 415 420
539. L.W. Tjoelker, C. Wilder, C. Eberhardt, D.M. Stafforini, G. Dietsch, and B. Schimpf Nature 374 1995 549 553
540. L.W. Tjoelker, C. Eberhardt, J. Unger, H.L. Trong, G.A. Zimmerman, and T.M. McIntyre J Biol Chem 270 1995 25481 25487
541. D.M. Stafforini, T.M. McIntyre, G.A. Zimmerman, and S.M. Prescott J Biol Chem 272 1997 17895 17898
542. D.M. Stafforini, L.W. Tjoelker, S.P. McCormick, D. Vaitkus, T.M. McIntyre, and P.W. Gray J Biol Chem 274 1999 7018 7024
543. U. Samanta, and B.J. Bahnson J Biol Chem 283 2008 31617 31624
544. K. Nakajima, M. Murakami, R. Yanoshita, Y. Samejima, K. Karasawa, and M. Setaka J Biol Chem 272 1997 19708 19713
545. K.M. Howard, J.E. Miller, M. Miwa, and M.S. Olson J Biol Chem 272 1997 27543 27548
546. K.M. Howard, and M.S. Olson J Biol Chem 275 2000 19891 19896
547. M. Miwa, T. Miyake, T. Yamanaka, J. Sugatani, Y. Suzuki, and S. Sakata J Clin Invest 82 1988 1983 1991
548. D.M. Stafforini, K. Satoh, D.L. Atkinson, L.W. Tjoelker, C. Eberhardt, and H. Yoshida J Clin Invest 97 1996 2784 2791
549. S. Kruse, X.Q. Mao, A. Heinzmann, S. Blattmann, M.H. Roberts, and S. Braun Am J Hum Genet 66 2000 1522 1530
550. S.M. Prescott, G.A. Zimmerman, D.M. Stafforini, and T.M. McIntyre Annu Rev Biochem 69 2000 419 445
551. C.H. Macphee, J.J. Nelson, and A. Zalewski Curr Opin Lipidol 16 2005 442 446
552. B. Davis, G. Koster, L.J. Douet, M. Scigelova, G. Woffendin, and J.M. Ward J Biol Chem 283 2008 6428 6437
553. C.J. Packard, D.S. O'Reilly, M.J. Caslake, A.D. McMahon, I. Ford, and J. Cooney N Engl J Med 343 2000 1148 1155
554. P. Vadas, M. Gold, B. Perelman, G.M. Liss, G. Lack, and T. Blyth N Engl J Med 358 2008 28 35
555. E. Ninio, D. Tregouet, J.L. Carrier, D. Stengel, C. Bickel, and C. Perret Hum Mol Genet 13 2004 1341 1351
556. A.M. Abuzeid, E. Hawe, S.E. Humphries, and P.J. Talmud Atherosclerosis 168 2003 283 288
557. C.H. MacPhee, K.E. Moores, H.F. Boyd, D. Dhanak, R.J. Ife, and C.A. Leach Biochem J 338 Pt 2 1999 479 487
558. R.L. Wilensky, Y. Shi, E.R. Mohler 3rd, D. Hamamdzic, M.E. Burgert, and J. Li Nat Med 14 2008 1059 1066
559. P.W. Serruys, H.M. Garcia-Garcia, P. Buszman, P. Erne, S. Verheye, and M. Aschermann Circulation 118 2008 1172 1182
560. K. Hattori, M. Hattori, H. Adachi, M. Tsujimoto, H. Arai, and K. Inoue J Biol Chem 270 1995 22308 22313
561. K. Hattori, H. Adachi, A. Matsuzawa, K. Yamamoto, M. Tsujimoto, and J. Aoki J Biol Chem 271 1996 33032 33038
562. A. Matsuzawa, K. Hattori, J. Aoki, H. Arai, and K. Inoue J Biol Chem 272 1997 32315 32320
563. K. Karasawa, X. Qiu, and T. Lee J Biol Chem 274 1999 8655 8661
564. K. Bae, L. Longobardi, K. Karasawa, B. Malone, T. Inoue, and J. Aoki J Biol Chem 275 2000 26704 26709
565. N. Kono, T. Inoue, Y. Yoshida, H. Sato, T. Matsusue, and H. Itabe J Biol Chem 283 2008 1628 1636
566. K. Umemura, I. Kato, Y. Hirashima, Y. Ishii, T. Inoue, and J. Aoki Stroke 38 2007 1063 1068
567. T. Inoue, A. Sugimoto, Y. Suzuki, M. Yamamoto, M. Tsujimoto, and K. Inoue Proc Natl Acad Sci USA 101 2004 13233 13238
568. M. Hattori, H. Adachi, J. Aoki, M. Tsujimoto, H. Arai, and K. Inoue J Biol Chem 270 1995 31345 31352
569. M. Hattori, H. Adachi, M. Tsujimoto, H. Arai, and K. Inoue J Biol Chem 269 1994 23150 23155
570. M. Hattori, H. Adachi, M. Tsujimoto, H. Arai, and K. Inoue Nature 370 1994 216 218
571. H. Adachi, M. Tsujimoto, M. Hattori, H. Arai, and K. Inoue Biochem Biophys Res Commun 214 1995 180 187
572. Y.S. Ho, L. Swenson, U. Derewenda, L. Serre, Y. Wei, and Z. Dauter Nature 385 1997 89 93
573. H. Manya, J. Aoki, H. Kato, J. Ishii, S. Hino, and H. Arai J Biol Chem 274 1999 31827 31832
574. T. Sapir, A. Cahana, R. Seger, S. Nekhai, and O. Reiner Eur J Biochem 265 1999 181 188
575. K. Kato, G.D. Clark, N.G. Bazan, and C.F. Zorumski Nature 367 1994 175 179
576. H. Manya, J. Aoki, M. Watanabe, T. Adachi, H. Asou, and Y. Inoue J Biol Chem 273 1998 18567 18572
577. N. Yamaguchi, H. Koizumi, J. Aoki, Y. Natori, K. Nishikawa, and Y. Takanezawa Genes Cells 12 2007 1153 1161
578. H. Koizumi, N. Yamaguchi, M. Hattori, T.O. Ishikawa, J. Aoki, and M.M. Taketo J Biol Chem 278 2003 12489 12494
579. W. Yan, A.H. Assadi, A. Wynshaw-Boris, G. Eichele, M.M. Matzuk, and G.D. Clark Proc Natl Acad Sci USA 100 2003 7189 7194
580. E. Kitsiouli, G. Nakos, and M.E. Lekka Biochim Biophys Acta 1792 2009 941 953
581. T.S. Kim, C.S. Sundaresh, S.I. Feinstein, C. Dodia, W.R. Skach, and M.K. Jain J Biol Chem 272 1997 2542 2550
582. J.W. Chen, C. Dodia, S.I. Feinstein, M.K. Jain, and A.B. Fisher J Biol Chem 275 2000 28421 28427
583. X. Wang, S.A. Phelan, K. Forsman-Semb, E.F. Taylor, C. Petros, and A. Brown J Biol Chem 278 2003 25179 25190
584. A.B. Fisher, C. Dodia, S.I. Feinstein, and R.S. Ho J Lipid Res 46 2005 1248 1256
585. H. Nakanishi, H. Shindou, D. Hishikawa, T. Harayama, R. Ogasawara, and A. Suwabe J Biol Chem 281 2006 20140 20147
586. J.P. Bridges, M. Ikegami, L.L. Brilli, X. Chen, R.J. Mason, and J.M. Shanon J Clin Invest 120 2010 1736 1748
587. M. Hiraoka, A. Abe, and J.A. Shayman J Biol Chem 277 2002 10090 10099
588. A. Abe, and J.A. Shayman J Lipid Res 50 2009 2027 2035
589. A. Abe, H.K. Poucher, M. Hiraoka, and J.A. Shayman J Lipid Res 45 2004 667 673
590. M. Hiraoka, A. Abe, Y. Lu, K. Yang, X. Han, and R.W. Gross Mol Cell Biol 26 2006 6139 6148
591. A. Abe, R. Kelly, J. Kollmeyer, M. Hiraoka, Y. Lu, and J.A. Shayman J Immunol 181 2008 7873 7881
592. A. Abe, R. Kelly, and J.A. Shayman J Lipid Res 51 2010 2464 2470
593. R.E. Duncan, E. Sarkadi-Nagy, K. Jaworski, M. Ahmadian, and H.S. Sul J Biol Chem 283 2008 25428 25436
594. A. Hajnal, R. Klemenz, and R. Schafer Oncogene 9 1994 479 490
595. C. Sers, U. Emmenegger, K. Husmann, K. Bucher, A.C. Andres, and R. Schafer J Cell Biol 136 1997 935 944
596. T. Uyama, J. Morishita, X.H. Jin, Y. Okamoto, K. Tsuboi, and N. Ueda J Lipid Res 50 2009 685 693
597. K. Jaworski, M. Ahmadian, R.E. Duncan, E. Sarkadi-Nagy, K.A. Varady, and M.K. Hellerstein Nat Med 15 2009 159 168
598. M. Sanchez-Alavez, I. Klein, S.E. Brownell, I.V. Tabarean, C.N. Davis, and B. Conti Proc Natl Acad Sci USA 104 2007 3009 3014
599. T. Uyama, X.H. Jin, K. Tsuboi, T. Tonai, and N. Ueda Biochim Biophys Acta 1791 2009 1114 1124