-
1
-
-
35148852816
-
The molecular basis of vulnerable plaque: Potential therapeutic role for immunomodulation
-
Wilensky RL, Hamamdzic D. The molecular basis of vulnerable plaque: potential therapeutic role for immunomodulation. Curr Opin Cardiol. 2007; 22:545-551.
-
(2007)
Curr Opin Cardiol.
, vol.22
, pp. 545-551
-
-
Wilensky, R.L.1
Hamamdzic, D.2
-
2
-
-
58149288126
-
Toll-like receptors: New therapeutic targets for the treatment of atherosclerosis, acute coronary syndromes, and myocardial failure
-
Erickson B, Sperber K, Frishman WH. Toll-like receptors: new therapeutic targets for the treatment of atherosclerosis, acute coronary syndromes, and myocardial failure. Cardiol Rev. 2008;16:273-279
-
(2008)
Cardiol Rev.
, vol.16
, pp. 273-279
-
-
Erickson, B.1
Sperber, K.2
Frishman, W.H.3
-
3
-
-
58149314083
-
Vaccines in development to prevent and treat athero-sclerotic disease
-
Riley E, Dasari V, Frishman WH, et al. Vaccines in development to prevent and treat athero-sclerotic disease. Cardiol Rev. 2008;16:288-300.
-
(2008)
Cardiol Rev.
, vol.16
, pp. 288-300
-
-
Riley, E.1
Dasari, V.2
Frishman, W.H.3
-
4
-
-
58149293460
-
Device-based nonspecific immunomodu-lation therapy (Celecade) and its potential role in the treatment of chronic heart failure
-
Sporter RJ, Kim JH, Frishman WH. Device-based nonspecific immunomodu-lation therapy (Celecade) and its potential role in the treatment of chronic heart failure. Cardiol Rev. 2008;16:280-287.
-
(2008)
Cardiol Rev.
, vol.16
, pp. 280-287
-
-
Sporter, R.J.1
Kim, J.H.2
Frishman, W.H.3
-
5
-
-
51749086370
-
Identifying the vulnerable patient with rupture-prone plaque
-
Weintraub HS. Identifying the vulnerable patient with rupture-prone plaque. Am J Cardiol. 2008;101:3F-10F.
-
(2008)
Am J Cardiol.
, vol.101
-
-
Weintraub, H.S.1
-
6
-
-
0034687446
-
West of scotland coronary prevention study group. lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease
-
Packard CJ, O'Reilly DS, Caslake MJ, et al; West of Scotland Coronary Prevention Study Group. Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. N Engl J Med. 2000;343: 1148-1155.
-
(2000)
N Engl J Med.
, vol.343
, pp. 1148-1155
-
-
Packard, C.J.1
O'Reilly, D.S.2
Caslake, M.J.3
-
7
-
-
4944261232
-
Lipoprotein-associated phospho-lipase A2 adds to risk prediction of incident coronary events by C-reactive protein in apparently healthy middle-aged men from the general population: Results from the 14-year follow-up of a large cohort from southern Germany
-
Koenig W, Khuseyinova N, Lowel H, et al. Lipoprotein-associated phospho-lipase A2 adds to risk prediction of incident coronary events by C-reactive protein in apparently healthy middle-aged men from the general population: results from the 14-year follow-up of a large cohort from southern Germany. Circulation. 2004;110:1903-1908.
-
(2004)
Circulation
, vol.110
, pp. 1903-1908
-
-
Koenig, W.1
Khuseyinova, N.2
Lowel, H.3
-
8
-
-
13444268943
-
Lipoprotein-associated phos-pholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: The Rotterdam study
-
Oei HH, van der Meer IM, Hofman A, et al. Lipoprotein-associated phos-pholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam study. Circulation. 2005;111:570-575.
-
(2005)
Circulation
, vol.111
, pp. 570-575
-
-
Oei, H.H.1
Van Der Meer, I.M.2
Hofman, A.3
-
9
-
-
39549091690
-
Lipoprotein-associated phospho-lipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: The rancho bernardo study
-
Daniels LB, Laughlin GA, Sarno MJ, et al. Lipoprotein-associated phospho-lipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the rancho bernardo study. J Am Coll Cardiol. 2008;51:913-919.
-
(2008)
J Am Coll Cardiol.
, vol.51
, pp. 913-919
-
-
Daniels, L.B.1
Laughlin, G.A.2
Sarno, M.J.3
-
10
-
-
0035498968
-
A prospective evaluation of lipoprotein-associated phospholipase A(2) levels and the risk of future cardiovascular events in women
-
Blake GJ, Dada N, Fox JC, et al. A prospective evaluation of lipoprotein-associated phospholipase A(2) levels and the risk of future cardiovascular events in women. J Am Coll Cardiol. 2001;38:1302-1306.
-
(2001)
J Am Coll Cardiol.
, vol.38
, pp. 1302-1306
-
-
Blake, G.J.1
Dada, N.2
Fox, J.C.3
-
11
-
-
1342331006
-
Lipoprotein-associated phos-pholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the atherosclerosis risk in communities (ARIC) study
-
Ballantyne CM, Hoogeveen RC, Bang H, et al. Lipoprotein-associated phos-pholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the atherosclerosis risk in communities (ARIC) study. Circulation. 2004;109:837-842.
-
(2004)
Circulation
, vol.109
, pp. 837-842
-
-
Ballantyne, C.M.1
Hoogeveen, R.C.2
Bang, H.3
-
12
-
-
14144256273
-
Association of lipoprotein-associated phospholipase A2 levels with coronary artery disease risk factors, angiographic coronary artery disease, and major adverse events at follow-up
-
Brilakis ES, McConnell JP, Lennon RJ, et al. Association of lipoprotein-associated phospholipase A2 levels with coronary artery disease risk factors, angiographic coronary artery disease, and major adverse events at follow-up. Eur Heart J. 2005;26:137-144.
-
(2005)
Eur Heart J.
, vol.26
, pp. 137-144
-
-
Brilakis, E.S.1
McConnell, J.P.2
Lennon, R.J.3
-
13
-
-
33745965348
-
Lipoprotein-associated phospho-lipase A2 predicts future cardiovascular events in patients with coronary heart disease independently of traditional risk factors, markers of inflammation, renal function, and hemodynamic stress
-
Koenig W, Twardella D, Brenner H, et al. Lipoprotein-associated phospho-lipase A2 predicts future cardiovascular events in patients with coronary heart disease independently of traditional risk factors, markers of inflammation, renal function, and hemodynamic stress. Arterioscler Thromb Vasc Biol. 2006;26:1586-1593.
-
(2006)
Arterioscler Thromb Vasc Biol.
, vol.26
, pp. 1586-1593
-
-
Koenig, W.1
Twardella, D.2
Brenner, H.3
-
14
-
-
33745475120
-
High lipoprotein-associated phospholipase A2 is a risk factor for recurrent coronary events in postinfarc-tion patients
-
Corsetti JP, Rainwater DL, Moss AJ, et al. High lipoprotein-associated phospholipase A2 is a risk factor for recurrent coronary events in postinfarc-tion patients. Clin Chem. 2006;52:1331-1338.
-
(2006)
Clin Chem.
, vol.52
, pp. 1331-1338
-
-
Corsetti, J.P.1
Rainwater, D.L.2
Moss, A.J.3
-
15
-
-
36048962679
-
Prognostic utility of lipoprotein-associated phospholipase A2 for cardiovascular outcomes in patients with stable coronary artery disease.
-
Sabatine MS, Morrow DA, O'Donoghue M, et al. Prognostic utility of lipoprotein-associated phospholipase A2 for cardiovascular outcomes in patients with stable coronary artery disease. Arterioscler Thromb Vasc Biol. 2007;27:2463-2469.
-
(2007)
Arterioscler Thromb Vasc Biol.
, vol.27
, pp. 2463-2469
-
-
Sabatine, M.S.1
Morrow, D.A.2
O'Donoghue, M.3
-
16
-
-
0142010569
-
Plasma PAF-acetylhydrolase in patients with coronary artery disease: Results of a cross-sectional analysis
-
Blankenberg S, Stengel D, Rupprecht HJ, et al. Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis. J Lipid Res. 2003;44:1381-1386.
-
(2003)
J Lipid Res.
, vol.44
, pp. 1381-1386
-
-
Blankenberg, S.1
Stengel, D.2
Rupprecht, H.J.3
-
17
-
-
23944434921
-
Association between lp-PLA2 and coronary artery disease: Focus on its relationship with lipoproteins and markers of inflammation and hemostasis
-
Khuseyinova N, Imhof A, Rothenbacher D, et al. Association between lp-PLA2 and coronary artery disease: focus on its relationship with lipoproteins and markers of inflammation and hemostasis. Atherosclerosis. 2005;182:181-188.
-
(2005)
Atherosclerosis
, vol.182
, pp. 181-188
-
-
Khuseyinova, N.1
Imhof, A.2
Rothenbacher, D.3
-
18
-
-
33750214642
-
Lipoprotein-associated phospholipase A2 and prognosis after myocardial infarction in the community
-
DOI 10.1161/01.ATV.0000240406.89440.0c, PII 0004360520061100000016
-
Gerber Y, McConnell JP, Jaffe AS, et al. Lipoprotein-associated phospho-lipase A2 and prognosis after myocardial infarction in the community. Arterioscler Thromb Vasc Biol. 2006;26:2517-2522. (Pubitemid 44607474)
-
(2006)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.26
, Issue.11
, pp. 2517-2522
-
-
Gerber, Y.1
McConnell, J.P.2
Jaffe, A.S.3
Weston, S.A.4
Killian, J.M.5
Roger, V.L.6
-
19
-
-
34547614814
-
Lipoprotein-associated phospholipase A2 predicts 5-year cardiac mortality independently of established risk factors and adds prognostic information in patients with low and medium high-sensitivity C-reactive protein (the ludwigshafen risk and cardiovascular health study)
-
Winkler K, Hoffmann MM, Winkelmann BR, et al. Lipoprotein-associated phospholipase A2 predicts 5-year cardiac mortality independently of established risk factors and adds prognostic information in patients with low and medium high-sensitivity C-reactive protein (the ludwigshafen risk and cardiovascular health study). Clin Chem. 2007;53:1440-1447.
-
(2007)
Clin Chem.
, vol.53
, pp. 1440-1447
-
-
Winkler, K.1
Hoffmann, M.M.2
Winkelmann, B.R.3
-
20
-
-
33751028489
-
The phospholipase A2 superfamily and its group numbering system
-
Schaloske RH, Dennis EA. The phospholipase A2 superfamily and its group numbering system. Biochim Biophys Acta. 2006;1761:1246-1259.
-
(2006)
Biochim Biophys Acta.
, vol.1761
, pp. 1246-1259
-
-
Schaloske, R.H.1
Dennis, E.A.2
-
22
-
-
0033548591
-
Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein
-
Stafforini DM, Tjoelker LW, McCormick SP, et al. Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein. J Biol Chem. 1999;274:7018-7024.
-
(1999)
J Biol Chem.
, vol.274
, pp. 7018-7024
-
-
Stafforini, D.M.1
Tjoelker, L.W.2
McCormick, S.P.3
-
23
-
-
0038352228
-
Inflammation, bioactive lipids and atherosclerosis: Potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase
-
Tselepis AD, John Chapman M. Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase. Atheroscler Suppl. 2002;3:57-68.
-
(2002)
Atheroscler Suppl.
, vol.3
, pp. 57-68
-
-
Tselepis, A.D.1
John Chapman, M.2
-
24
-
-
0001096583
-
Lysophosphatidylcholine: A che-motactic factor for human monocytes and its potential role in atherogenesis
-
Quinn MT, Parthasarathy S, Steinberg D. Lysophosphatidylcholine: a che-motactic factor for human monocytes and its potential role in atherogenesis. Proc Natl Acad Sci USA. 1988;85:2805-2809.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 2805-2809
-
-
Quinn, M.T.1
Parthasarathy, S.2
Steinberg, D.3
-
25
-
-
18244373708
-
2 in atherosclerosis: Biology, epidemiology, and possible therapeutic target
-
DOI 10.1161/01.ATV.0000160551.21962.a7
-
Zalewski A, Macphee C. Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target. Arte-rioscler Thromb Vasc Biol. 2005;25:923-931. (Pubitemid 40627835)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.5
, pp. 923-931
-
-
Zalewski, A.1
Macphee, C.2
-
26
-
-
34249701265
-
Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: Association with early coronary atherosclerosis and endothelial dysfunction in humans
-
Lavi S, McConnell JP, Rihal CS, et al. Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: association with early coronary atherosclerosis and endothelial dysfunction in humans. Circulation. 2007;115:2715-2721.
-
(2007)
Circulation
, vol.115
, pp. 2715-2721
-
-
Lavi, S.1
McConnell, J.P.2
Rihal, C.S.3
-
27
-
-
33846658406
-
Association between lipoprotein-associated phospholipase A2 and cardiovascular disease: A systematic review
-
Garza CA, Montori VM, McConnell JP, et al. Association between lipoprotein-associated phospholipase A2 and cardiovascular disease: a systematic review. Mayo Clin Proc. 2007;82:159-165.
-
(2007)
Mayo Clin Proc.
, vol.82
, pp. 159-165
-
-
Garza, C.A.1
Montori, V.M.2
McConnell, J.P.3
-
28
-
-
0035998298
-
Lp-PLA2: An emerging biomarker of coronary heart disease
-
Dada N, Kim NW, Wolfert RL. Lp-PLA2: an emerging biomarker of coronary heart disease. Expert Rev Mol Diagn. 2002;2:17-22.
-
(2002)
Expert Rev Mol Diagn.
, vol.2
, pp. 17-22
-
-
Dada, N.1
Kim, N.W.2
Wolfert, R.L.3
-
29
-
-
0033104911
-
Lipoprotein-associated phospho-lipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: Use of a novel inhibitor
-
MacPhee CH, Moores KE, Boyd HF, et al. Lipoprotein-associated phospho-lipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor. Biochem J. 1999;338(pt 2):479-487.
-
(1999)
Biochem J.
, vol.338
, Issue.PART 2
, pp. 479-487
-
-
MacPhee, C.H.1
Moores, K.E.2
Boyd, H.F.3
-
31
-
-
43049122963
-
The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: The results of a multicenter, randomized, double-blind, placebo-controlled study
-
Mohler ER III, Ballantyne CM, Davidson MH, et al. The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study. J Am Coll Cardiol. 2008;51:1632-1641.
-
(2008)
J Am Coll Cardiol.
, vol.51
, pp. 1632-1641
-
-
Mohler Er, I.I.I.1
Ballantyne, C.M.2
Davidson, M.H.3
-
32
-
-
0033815584
-
HDL-associated PAF-AH reduces endothelial adhesiveness in apoE-/-mice
-
Theilmeier G, De Geest B, Van Veldhoven PP, et al. HDL-associated PAF-AH reduces endothelial adhesiveness in apoE-/-mice. FASEB J. 2000;14:2032-2039.
-
(2000)
FASEB J.
, vol.14
, pp. 2032-2039
-
-
Theilmeier, G.1
De Geest, B.2
Van Veldhoven, P.P.3
-
33
-
-
0035933117
-
Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipopro-tein E-deficient mice
-
Quarck R, De Geest B, Stengel D, et al. Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipopro-tein E-deficient mice. Circulation. 2001;103:2495-2500.
-
(2001)
Circulation
, vol.103
, pp. 2495-2500
-
-
Quarck, R.1
De Geest, B.2
Stengel, D.3
-
34
-
-
0028287199
-
The mouse plasma PAF acetylhydrolase: II. It consists of two enzymes both associated with the HDL
-
Tsaoussis V, Vakirtzi-Lemonias C. The mouse plasma PAF acetylhydrolase: II. It consists of two enzymes both associated with the HDL. J Lipid Mediat Cell Signal. 1994;9:317-331.
-
(1994)
J Lipid Mediat Cell Signal.
, vol.9
, pp. 317-331
-
-
Tsaoussis, V.1
Vakirtzi-Lemonias, C.2
-
35
-
-
2342425088
-
Increased plasma nonesterified fatty acids and platelet-activating factor acetylhydrolase are associated with susceptibility to atherosclerosis in mice
-
Singh U, Zhong S, Xiong M, et al. Increased plasma nonesterified fatty acids and platelet-activating factor acetylhydrolase are associated with susceptibility to atherosclerosis in mice. Clin Sci (Lond). 2004;106:421-432.
-
(2004)
Clin Sci (Lond)
, vol.106
, pp. 421-432
-
-
Singh, U.1
Zhong, S.2
Xiong, M.3
-
36
-
-
33846858869
-
Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses
-
Shi Y, Zhang P, Zhang L, et al. Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses. Atherosclerosis. 2007;191:54-62.
-
(2007)
Atherosclerosis
, vol.191
, pp. 54-62
-
-
Shi, Y.1
Zhang, P.2
Zhang, L.3
-
37
-
-
53549093853
-
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
-
Wilensky RL, Shi Y, Mohler ER III, et al. Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development. Nat Med. 2008;14:1059-1066.
-
(2008)
Nat Med.
, vol.14
, pp. 1059-1066
-
-
Wilensky, R.L.1
Shi, Y.2
Mohler Er, I.I.I.3
-
38
-
-
33750223516
-
Lipoprotein-associated phospho-lipase A2 protein expression in the natural progression of human coronary atherosclerosis
-
Kolodgie FD, Burke AP, Skorija KS, et al. Lipoprotein-associated phospho-lipase A2 protein expression in the natural progression of human coronary atherosclerosis. Arterioscler Thromb Vasc Biol. 2006;26:2523-2529.
-
(2006)
Arterioscler Thromb Vasc Biol.
, vol.26
, pp. 2523-2529
-
-
Kolodgie, F.D.1
Burke, A.P.2
Skorija, K.S.3
-
39
-
-
0343852114
-
Lipoprotein-associated phospho-lipase A(2), platelet-activating factor acetylhydrolase, is expressed by macrophages in human and rabbit atherosclerotic lesions
-
Hakkinen T, Luoma JS, Hiltunen MO, et al. Lipoprotein-associated phospho-lipase A(2), platelet-activating factor acetylhydrolase, is expressed by mac-rophages in human and rabbit atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 1999;19:2909-2917.
-
(1999)
Arterioscler Thromb Vasc Biol.
, vol.19
, pp. 2909-2917
-
-
Hakkinen, T.1
Luoma, J.S.2
Hiltunen, M.O.3
-
40
-
-
44449157784
-
Enhanced expression of lp-PLA2 and lysophosphatidylcholine in symptomatic carotid atherosclerotic plaques
-
Mannheim D, Herrmann J, Versari D, et al. Enhanced expression of lp-PLA2 and lysophosphatidylcholine in symptomatic carotid atherosclerotic plaques. Stroke. 2008;39:1448-1455.
-
(2008)
Stroke
, vol.39
, pp. 1448-1455
-
-
Mannheim, D.1
Herrmann, J.2
Versari, D.3
-
41
-
-
51749095275
-
2 and rist of strok.
-
Gorelick PB. Lipoprotein-associated phospholipase and risk of stroke. A2 Am J Cardiol. 2008;101:34F- 40F.
-
(2008)
Am J Cardiol.
, vol.101
-
-
Gorelick, P.B.1
-
42
-
-
46349094873
-
Lipoprotein-associated phospholipase A2: An independent predictor of coronary artery disease events in primary and secondary prevention
-
Anderson JL. Lipoprotein-associated phospholipase A2: an independent predictor of coronary artery disease events in primary and secondary prevention. Am J Cardiol. 2008;101:23F-33F.
-
(2008)
Am J Cardiol.
, vol.101
-
-
Anderson, J.L.1
-
43
-
-
0035321963
-
Lipoprotein-associated phospholipase A2: A potential new risk factor for coronary artery disease and a therapeutic target
-
Macphee CH. Lipoprotein-associated phospholipase A2: a potential new risk factor for coronary artery disease and a therapeutic target. Curr Opin Pharmacol. 2001;1:121-125.
-
(2001)
Curr Opin Pharmacol.
, vol.1
, pp. 121-125
-
-
MacPhee, C.H.1
-
44
-
-
0035929246
-
Inhibition of lipoprotein-associated phospholipase A2 diminishes the death-inducing effects of oxidized LDL on human monocyte-macrophages
-
Carpenter KL, Dennis IF, Challis IR, et al. Inhibition of lipoprotein-associated phospholipase A2 diminishes the death-inducing effects of oxidized LDL on human monocyte-macrophages. FEBS Lett. 2001;505:357-363.
-
(2001)
FEBS Lett.
, vol.505
, pp. 357-363
-
-
Carpenter, K.L.1
Dennis, I.F.2
Challis, I.R.3
-
45
-
-
3042719884
-
Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (lp-PLA2) deficiency patients
-
Ishihara M, Iwasaki T, Nagano M, et al. Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (lp-PLA2) deficiency patients. J Hum Genet. 2004;49:302-307.
-
(2004)
J Hum Genet.
, vol.49
, pp. 302-307
-
-
Ishihara, M.1
Iwasaki, T.2
Nagano, M.3
-
46
-
-
0034181353
-
Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population
-
Yamada Y, Yoshida H, Ichihara S, et al. Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population. Atherosclerosis. 2000;150:209-216.
-
(2000)
Atherosclerosis
, vol.150
, pp. 209-216
-
-
Yamada, Y.1
Yoshida, H.2
Ichihara, S.3
-
47
-
-
0033844713
-
Plasma platelet-activating factor acetylhydrolase deficiency is associated with atherosclerotic occlusive disease in Japan
-
Unno N, Nakamura T, Kaneko H, et al. Plasma platelet-activating factor acetylhydrolase deficiency is associated with atherosclerotic occlusive disease in Japan. J Vasc Surg. 2000;32:263-267.
-
(2000)
J Vasc Surg.
, vol.32
, pp. 263-267
-
-
Unno, N.1
Nakamura, T.2
Kaneko, H.3
-
48
-
-
33748752140
-
The Val279Phe variant of the lipoprotein-associated phospholipase A2 gene is associated with catalytic activities and cardiovascular disease in Korean men
-
Jang Y, Kim OY, Koh SJ, et al. The Val279Phe variant of the lipoprotein-associated phospholipase A2 gene is associated with catalytic activities and cardiovascular disease in Korean men. J Clin Endocrinol Metab. 2006;91: 3521-3527.
-
(2006)
J Clin Endocrinol Metab.
, vol.91
, pp. 3521-3527
-
-
Jang, Y.1
Kim, O.Y.2
Koh, S.J.3
-
49
-
-
0033941665
-
The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma
-
Kruse S, Mao XQ, Heinzmann A, et al. The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma. Am J Hum Genet. 2000;66:1522-1530.
-
(2000)
Am J Hum Genet.
, vol.66
, pp. 1522-1530
-
-
Kruse, S.1
Mao, X.Q.2
Heinzmann, A.3
-
50
-
-
0037497958
-
Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe
-
Abuzeid AM, Hawe E, Humphries SE, et al. Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe. Atherosclerosis. 2003;168:283-288.
-
(2003)
Atherosclerosis
, vol.168
, pp. 283-288
-
-
Abuzeid, A.M.1
Hawe, E.2
Humphries, S.E.3
-
51
-
-
3242712234
-
Platelet-activating factor-acetylhydro-lase and PAF-receptor gene haplotypes in relation to future cardiovascular event in patients with coronary artery disease
-
Ninio E, Tregouet D, Carrier JL, et al. Platelet-activating factor-acetylhydro-lase and PAF-receptor gene haplotypes in relation to future cardiovascular event in patients with coronary artery disease. Hum Mol Genet. 2004;13: 1341-1351.
-
(2004)
Hum Mol Genet.
, vol.13
, pp. 1341-1351
-
-
Ninio, E.1
Tregouet, D.2
Carrier, J.L.3
-
52
-
-
51749105639
-
Review of the evidence for the clinical utility of lipoprotein-associated phospholipase as a cardiovascular risk A2 marker
-
Corson MA, Jones PH, Davidson MH. Review of the evidence for the clinical utility of lipoprotein-associated phospholipase as a cardiovascular risk A2 marker. Am J Cardiol. 2008;101:41F-50F.
-
(2008)
Am J Cardiol.
, vol.101
-
-
Corson, M.A.1
Jones, P.H.2
Davidson, M.H.3
-
53
-
-
60249094866
-
Use of biomarkers to develop treatment strategies for atherosclerosis
-
Crandall AM, Corson MA. Use of biomarkers to develop treatment strategies for atherosclerosis. Curr Treat Options Cardiovasc Med. 2008;10:304-315.
-
(2008)
Curr Treat Options Cardiovasc Med.
, vol.10
, pp. 304-315
-
-
Crandall, A.M.1
Corson, M.A.2
-
54
-
-
0034035763
-
Lipoprotein-associated phos-pholipase A(2), platelet-activating factor acetylhydrolase: A potential new risk factor for coronary artery disease
-
Caslake MJ, Packard CJ, Suckling KE, et al. Lipoprotein-associated phos-pholipase A(2), platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease. Atherosclerosis. 2000;150:413-419.
-
(2000)
Atherosclerosis
, vol.150
, pp. 413-419
-
-
Caslake, M.J.1
Packard, C.J.2
Suckling, K.E.3
-
55
-
-
12344308132
-
PLAC test for identification of individuals at increased risk for coronary heart disease
-
Hoogeveen RC, Ballantyne CM. PLAC test for identification of individuals at increased risk for coronary heart disease. Expert Rev Mol Diagn. 2005;5:9-14.
-
(2005)
Expert Rev Mol Diagn.
, vol.5
, pp. 9-14
-
-
Hoogeveen, R.C.1
Ballantyne, C.M.2
-
56
-
-
18844433282
-
Clinical review: Lipoprotein-associated phospholipase A2, a novel inflammatory biomarker and independent risk predictor for cardiovascular disease
-
Sudhir K. Clinical review: lipoprotein-associated phospholipase A2, a novel inflammatory biomarker and independent risk predictor for cardiovascular disease. J Clin Endocrinol Metab. 2005;90:3100-3105.
-
(2005)
J Clin Endocrinol Metab.
, vol.90
, pp. 3100-3105
-
-
Sudhir, K.1
-
57
-
-
28344441841
-
Lipoprotein-associated phos-pholipase A2, high-sensitivity C-reactive protein, and risk for incident isch-emic stroke in middle-aged men and women in the atherosclerosis risk in communities (ARIC) study
-
Ballantyne CM, Hoogeveen RC, Bang H, et al. Lipoprotein-associated phos-pholipase A2, high-sensitivity C-reactive protein, and risk for incident isch-emic stroke in middle-aged men and women in the atherosclerosis risk in communities (ARIC) study. Arch Intern Med. 2005;165:2479-2484.
-
(2005)
Arch Intern Med.
, vol.165
, pp. 2479-2484
-
-
Ballantyne, C.M.1
Hoogeveen, R.C.2
Bang, H.3
-
58
-
-
33646685941
-
Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin or atorVastatin evaluation and infection therapy-thrombolysis in myocardial infarction) trial
-
O'Donoghue M, Morrow DA, Sabatine MS, et al. Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin or atorVastatin evaluation and infection therapy-thrombolysis in myocardial infarction) trial. Circulation. 2006;113:1745-1752.
-
(2006)
Circulation
, vol.113
, pp. 1745-1752
-
-
O'Donoghue, M.1
Morrow, D.A.2
Sabatine, M.S.3
-
59
-
-
33644830673
-
Lipoprotein-associated phospho-lipase A2 is an independent marker for coronary endothelial dysfunction in humans
-
Yang EH, McConnell JP, Lennon RJ, et al. Lipoprotein-associated phospho-lipase A2 is an independent marker for coronary endothelial dysfunction in humans. Arterioscler Thromb Vasc Biol. 2006;26:106-111.
-
(2006)
Arterioscler Thromb Vasc Biol.
, vol.26
, pp. 106-111
-
-
Yang, E.H.1
McConnell, J.P.2
Lennon, R.J.3
-
60
-
-
35148866515
-
Differential effect of hypo-lipidemic drugs on lipoprotein-associated phospholipase A2
-
Saougos VG, Tambaki AP, Kalogirou M, et al. Differential effect of hypo-lipidemic drugs on lipoprotein-associated phospholipase A2. Arterioscler Thromb Vasc Biol. 2007;27:2236-2243.
-
(2007)
Arterioscler Thromb Vasc Biol.
, vol.27
, pp. 2236-2243
-
-
Saougos, V.G.1
Tambaki, A.P.2
Kalogirou, M.3
-
61
-
-
17444394505
-
Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects
-
Schaefer EJ, McNamara JR, Asztalos BF, et al. Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects. Am J Cardiol. 2005;95:1025-1032.
-
(2005)
Am J Cardiol.
, vol.95
, pp. 1025-1032
-
-
Schaefer, E.J.1
McNamara, J.R.2
Asztalos, B.F.3
-
62
-
-
23944457321
-
The effect of statin therapy on lipoprotein associated phospholipase A2 levels
-
Albert MA, Glynn RJ, Wolfert RL, et al. The effect of statin therapy on lipoprotein associated phospholipase A2 levels. Atherosclerosis. 2005;182: 193-198.
-
(2005)
Atherosclerosis
, vol.182
, pp. 193-198
-
-
Albert, M.A.1
Glynn, R.J.2
Wolfert, R.L.3
-
63
-
-
39149145837
-
Fenofibrate reduces lipoprotein associated phospholipase A2 mass and oxidative lipids in hypertriglyceridemic subjects with the metabolic syndrome
-
Rosenson RS. Fenofibrate reduces lipoprotein associated phospholipase A2 mass and oxidative lipids in hypertriglyceridemic subjects with the metabolic syndrome. Am Heart J. 2008;155:499.e9 - 499.e16.
-
(2008)
Am Heart J.
, vol.155
-
-
Rosenson, R.S.1
-
64
-
-
70349099856
-
-
Available at Accessed May 3
-
GlaxoSmithKline. Available at: http://www.gsk.com/investors/product- pipeline/pp.htm. Accessed May 3, 2008.
-
(2008)
-
-
-
65
-
-
0037463766
-
The identification of clinical candidate SB-480848: A potent inhibitor of lipoprotein-associated phospho-lipase A2
-
Blackie JA, Bloomer JC, Brown MJ, et al. The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospho-lipase A2. Bioorg Med Chem Lett. 2003;13:1067-1070.
-
(2003)
Bioorg Med Chem Lett.
, vol.13
, pp. 1067-1070
-
-
Blackie, J.A.1
Bloomer, J.C.2
Brown, M.J.3
-
66
-
-
54049152760
-
Effects of the direct lipoprotein-associated phospholipase A2 inhibitor darapladib on human coronary atherosclerotic plaque
-
Serruys PW, Garcia-Garcia HM, Buszman P, et al. Effects of the direct lipoprotein-associated phospholipase A2 inhibitor darapladib on human coronary atherosclerotic plaque. Circulation. 2008;118:1172-1182.
-
(2008)
Circulation
, vol.118
, pp. 1172-1182
-
-
Serruys, P.W.1
Garcia-Garcia, H.M.2
Buszman, P.3
-
68
-
-
34347332211
-
Role of lipoprotein-associated phospholipase A2 in predicting risk of cardiovascular disease
-
author reply 888-889
-
Myerson M. Role of lipoprotein-associated phospholipase A2 in predicting risk of cardiovascular disease. Mayo Clin Proc. 2007;82:888; author reply 888-889.
-
(2007)
Mayo Clin Proc.
, vol.82
, pp. 888
-
-
Myerson, M.1
-
69
-
-
0142120730
-
Novel risk markers and clinical practice
-
Manolio T. Novel risk markers and clinical practice. N Engl J Med. 2003; 349:1587-1589.
-
(2003)
N Engl J Med.
, vol.349
, pp. 1587-1589
-
-
Manolio, T.1
-
70
-
-
38749105802
-
Variability of serial lipoprotein-associated phospholipase A2 measurements in postmyocardial infarction patients: Results from the AIRGENE study center Augsburg
-
Khuseyinova N, Greven S, Ruckerl R, et al. Variability of serial lipoprotein-associated phospholipase A2 measurements in postmyocardial infarction patients: results from the AIRGENE study center Augsburg. Clin Chem. 2008;54:124-130.
-
(2008)
Clin Chem.
, vol.54
, pp. 124-130
-
-
Khuseyinova, N.1
Greven, S.2
Ruckerl, R.3
-
71
-
-
0037472879
-
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes
-
DOI 10.1056/NEJMoa021778
-
Gaede P, Vedel P, Larsen N, et al. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med. 2003;348:383-393. (Pubitemid 36159355)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.5
, pp. 383-393
-
-
Gaede, P.1
Vedel, P.2
Larsen, N.3
Jensen, G.V.H.4
Parving, H.-H.5
Pedersen, O.6
-
72
-
-
43049105416
-
Treating residual cardiovascular risk: Will lipoprotein-associated phospholipase A2 inhibition live up to its promise?
-
Koenig W. Treating residual cardiovascular risk: will lipoprotein-associated phospholipase A2 inhibition live up to its promise? J Am Coll Cardiol. 2008;51:1642-1644.
-
(2008)
J Am Coll Cardiol.
, vol.51
, pp. 1642-1644
-
-
Koenig, W.1
|