Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila

Journal of Neuroscience

Volumn 25, Issue 11, 2005, Pages 2865-2873

  Mühlig Versen, Max ^b   Da Cruz, Alexandre Bettencourt ^a   Tschäpe, Jakob Andreas ^a   Moser, Markus ^c   Büttner, Reinhard ^d   Athenstaedt, Karin ^e   Glynn, Paul ^f   Kretzschmar, Doris ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d UNIVERSITY OF BONN   (Germany)

^e GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^f UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Drosophila; ER; Neurodegeneration; NTE; Organophosphate induced delayed neuropathy; Phospholipids

Indexed keywords

ESTERASE; PHOSPHATIDYLCHOLINE; PROTEIN; PROTEIN SWISS CHEESE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CATALYSIS; CELL CULTURE; CELL DEATH; CELL DISRUPTION; CELL SURVIVAL; DROSOPHILA; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GLIA CELL; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR MEMBRANE; MEMBRANE STRUCTURE; MOUSE; MUTANT; NERVE CELL; NERVE CELL DEGENERATION; NERVE FIBER DEGENERATION; NERVOUS SYSTEM; NEUROPATHY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; WESTERN BLOTTING; WILD TYPE;

EID: 15244351250     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5097-04.2005     Document Type: Article

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