Macrophage polarization comes of age

Immunity

Volumn 23, Issue 4, 2005, Pages 344-346

  Mantovani, Alberto ^a,b   Sica, Antonio ^a   Locati, Massimo ^a,b  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR8; CHEMOKINE RECEPTOR CXCR1; CYTOKINE; GAMMA INTERFERON; GLUCOCORTICOID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 23; INTERLEUKIN 4; SECOSTEROID; TUMOR NECROSIS FACTOR;

AGING; CELL POLARITY; GENE EXPRESSION; GENETICS; LUNG ALVEOLUS; MACROPHAGE; MONOCYTE; NONHUMAN; PHAGOCYTE; PLASTICITY; POLARIZATION; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL; TRANSGENE;

CELL DIFFERENTIATION; MACROPHAGES;

EID: 26644452073     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.10.001     Document Type: Short Survey

References (13)

1. C.A. Dinarello Blocking IL-1 in systemic inflammation J. Exp. Med. 201 2005 1355 1359
2. J.S. Duffield, S.J. Forbes, C.M. Constandinou, S. Clay, M. Partolina, S. Vuthoori, S. Wu, R. Lang, and J.P. Iredale Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair J. Clin. Invest. 115 2005 56 65
3. H. Fang, R.A. Pengal, X. Cao, L.P. Ganesan, M.D. Wewers, C.B. Marsh, and S. Tridandapani Lipopolysaccharide-induced macrophage inflammatory response is regulated by SHIP J. Immunol. 173 2004 360 366
4. S. Gordon Alternative activation of macrophages Nat. Rev. Immunol. 3 2003 23 35
5. D.R. Herbert, C. Holscher, M. Mohrs, B. Arendse, A. Schwegmann, M. Radwanska, M. Leeto, R. Kirsch, P. Hall, and H. Mossmann Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology Immunity 20 2004 623 635
6. A. Mantovani, S. Sozzani, M. Locati, P. Allavena, and A. Sica Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Trends Immunol. 23 2002 549 555
7. A. Mantovani, A. Sica, S. Sozzani, P. Allavena, A. Vecchi, and M. Locati The chemokine system in diverse forms of macrophage activation and polarization Trends Immunol. 25 2004 677 686
8. W. Noel, G. Raes, G. Hassanzadeh Ghassabeh, P. De Baetselier, and A. Beschin Alternatively activated macrophages during parasite infections Trends Parasitol. 20 2004 126 133
9. S.L. Pull, J.M. Doherty, J.C. Mills, J.I. Gordon, and T.S. Stappenbeck Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury Proc. Natl. Acad. Sci. USA 102 2005 99 104
10. M.J. Rauh, V. Ho, C. Pereira, A. Sham, L.M. Sly, V. Lam, L. Huxham, A.I. Minchinton, A. Mui, and G. Krystal SHIP represses the generation of alternatively activated macrophages this issue Immunity 24 2005 361 374
11. C.J. Scotton, F.O. Martinez, M.J. Smelt, M. Sironi, M. Locati, A. Mantovani, and S. Sozzani Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13 J. Immunol. 174 2005 834 845
12. T.A. Wynn Fibrotic disease and the T(H)1/T(H)2 paradigm Nat. Rev. Immunol. 4 2004 583 594
13. Z. Zhu, T. Zheng, R.J. Homer, Y.K. Kim, N.Y. Chen, L. Cohn, Q. Hamid, and J.A. Elias Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation Science 304 2004 1678 1682