Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

Science

Volumn 306, Issue 5700, 2004, Pages 1383-1386

  Zimmermann, Robert ^a   Strauss, Juliane G ^a   Haemmerle, Guenter ^a   Schoiswohl, Gabriele ^a   Birner Gruenberger, Ruth ^c   Riederer, Monika ^a   Lass, Achim ^a   Neuberger, Georg ^b   Eisenhaber, Frank ^b   Hermetter, Albin ^c   Zechner, Rudolf ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^c GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; HYDROLYSIS; INSULIN; SUBSTRATES;

ADIPOSE TISSUES; HORMONE-SENSITIVE LIPASE (HSL); LIPOLYTIC ENZYMES;

TISSUE;

FAT DROPLET; HORMONE SENSITIVE LIPASE; HYDROLASE; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE;

ENZYME; FATTY ACID;

ADIPOSE TISSUE; ARTICLE; ENERGY BALANCE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; FATTY ACID METABOLISM; HUMAN; HYDROLYSIS; INSULIN RESISTANCE; LIPID METABOLISM; LIPOLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PATATIN DOMAIN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOSE TISSUE; ADIPOSE TISSUE, BROWN; AMINO ACID SEQUENCE; ANIMALS; CHOLESTEROL ESTERASE; COS CELLS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOPLASM; DIGLYCERIDES; DNA, COMPLEMENTARY; FATTY ACIDS; GENE SILENCING; GLYCEROL; HUMANS; ISOPROTERENOL; LIPID MOBILIZATION; LIPOLYSIS; LIPOPROTEIN LIPASE; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TRANSFECTION; TRIGLYCERIDES;

MAMMALIA;

EID: 8844226709     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1100747     Document Type: Article

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25. This work was supported by the Austrian Federal Ministery of Education, Science, and Culture (G.O.L.D., Genomics of Lipid-Associated Disorders and B.I.N., Bioinformatics Network) and by the Austrian Fonds zur Förderung der Wissenschaftlichen Forschung (SFB Biomembranes F00701 and F007013). The authors thank G. Hoefler and M. Asslaber for the provision of human tissue biopsies, R. Schreiber and S. Eder for technical assistance, and E. Zechner for critically reviewing the manuscript.