Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: Results from the UDACS study

Human Molecular Genetics

Volumn 16, Issue 12, 2007, Pages 1437-1444

  Wootton, Peter T E ^a   Arora, Nupur L ^a   Drenos, Fotios ^a   Thompson, Simon R ^a   Cooper, Jackie A ^a   Stephens, Jeffrey W ^b   Hurel, Steven J ^c   Hurt Camejo, Eva ^d,e   Wiklund, Olov ^e   Humphries, Steve E ^a   Talmud, Philippa J ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d ASTRAZENECA R AND D   (Sweden)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPASE; SECRETORY PHOSPHOLIPASE 2A; SECRETORY PHOSPHOLIPASE A2G5; UNCLASSIFIED DRUG;

AGED; ARTICLE; ATHEROSCLEROSIS; CORONARY RISK; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE TAGGED SITE; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; CHOLESTEROL, LDL; COHORT STUDIES; FEMALE; GENOTYPE; HAPLOTYPES; HUMANS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; PHOSPHOLIPASES A; POLYMORPHISM, SINGLE NUCLEOTIDE;

ANIMALIA;

EID: 34447344534     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm094     Document Type: Article

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