Cytosolic phospholipase A2α-deficient mice are resistant to collagen-induced arthritis

Journal of Experimental Medicine

Volumn 197, Issue 10, 2003, Pages 1297-1302

  Hegen, Martin ^a   Sun, Linhong ^a   Uozumi, Naonori ^b   Kume, Kazuhiko ^b   Goad, Mary E ^a   Nickerson Nutter, Cheryl L ^a   Shimizu, Takao ^b   Clark, James D ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Autoimmunity; Gene targeting; Inflammation; Lipid mediators; Rheumatoid arthritis

Indexed keywords

COLLAGEN; COLLAGEN ANTIBODY; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 ALPHA; UNCLASSIFIED DRUG; 5-LIPOXYGENASE-ACTIVATING PROTEIN; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CARRIER PROTEIN; CYCLOOXYGENASE 2; EP4 RECEPTOR; IMMUNOGLOBULIN G; ISOENZYME; MEMBRANE PROTEIN; PHOSPHOLIPASE A; PHOSPHOLIPASE A2-ALPHA; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANKYLOSIS; ANTIBODY DETECTION; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; ENZYME DEFICIENCY; GENE TARGETING; HISTOPATHOLOGY; MEDIATOR RELEASE; MOUSE; NONHUMAN; PANNUS; PATHOGENESIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RHEUMATOID ARTHRITIS; SCORING SYSTEM; WILD TYPE; ANIMAL; ARTHRITIS; BLOOD; C57BL MOUSE; CLASSIFICATION; CYTOSOL; DBA MOUSE; ENZYMOLOGY; IMMUNIZATION; IMMUNOLOGY; PHYSIOLOGY;

ANIMALS; ARTHRITIS; CARRIER PROTEINS; COLLAGEN; CYCLOOXYGENASE 2; CYTOSOL; IMMUNIZATION; IMMUNOGLOBULIN G; ISOENZYMES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; PHOSPHOLIPASES A; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, PROSTAGLANDIN E;

EID: 0037561999     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20030016     Document Type: Article

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