Deorphanization of GPR109B as a receptor for the β-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis

Journal of Biological Chemistry

Volumn 284, Issue 33, 2009, Pages 21928-21933

  Ahmed, Kashan ^a   Tunaru, Sorin ^a   Langhans, Claus Dieter ^b   Hanson, Julien ^a,c   Michalski, Christoph W ^d   Kölker, Stefan ^b   Jones, Patricia M ^e   Okun, Jürgen G ^b   Offermanns, Stefan ^a,f  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTE LIPOLYSIS; ADIPOCYTES; G PROTEIN; G PROTEIN COUPLED RECEPTORS; GENE DUPLICATIONS; KETONE BODIES; LIGAND-RECEPTOR PAIR; MICROMOLAR CONCENTRATION; NEGATIVE FEEDBACK; NICOTINIC ACID; OCTANOIC ACIDS; OXIDATION RATES; PLASMA CONCENTRATION;

ENZYMES; FATTY ACIDS; FEEDBACK; KETONES; MAMMALS; OXIDATION; SUGAR (SUCROSE);

ACIDS;

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 109B; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; OCTANOIC ACID; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; EPILEPSY; FATTY ACID BLOOD LEVEL; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KETOGENIC DIET; LIPOLYSIS; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION;

ADIPOCYTES; ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; LIGANDS; LIPOLYSIS; MICE; MODELS, BIOLOGICAL; OCTANOIC ACIDS; OXYGEN; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC;

MURINAE; RODENTIA;

EID: 69249083201     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.019455     Document Type: Article

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