Modulation of acute and chronic inflammatory processes by cacospongionolide B, a novel inhibitor of human synovial phospholipase A2

British Journal of Pharmacology

Volumn 126, Issue 1, 1999, Pages 301-311

  Pastor, Pablo Garcia ^a   De Rosa, Saivatore ^a   De Giulio, Alfonso ^b   Paya, Miguel ^b   Jose Alcaraz M ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b Istituto per la Chimica di Molecole di Interesse Biologico   (Italy)

Author keywords

Adjuvant arthritis; Cacospongionolide b; Inflammation; Manoalide; Phospholipase a2; Rat and mouse air pouch

Indexed keywords

CACOSPONGIONOLIDE B; CARRAGEENAN; ICOSANOID; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZYMOSAN;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC INFLAMMATION; EAR; EDEMA; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SYNOVIUM;

4-BUTYROLACTONE; ACUTE DISEASE; ANIMALS; ANTI-INFECTIVE AGENTS; ARTHRITIS, EXPERIMENTAL; CHRONIC DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; EAR; EDEMA; ENZYMES; FEMALE; HUMANS; INFLAMMATION; LEUKOCYTES; MALE; MICE; PHOSPHOLIPASES A; PYRANS; RATS; RATS, WISTAR; SYNOVIAL FLUID; U937 CELLS;

EID: 0032919503     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702302     Document Type: Article

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