-
1
-
-
9344257283
-
Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis
-
Boolbol, S.K., Dannenberg, A.J., Chadburn, A., Martucci, C., Guo, X.J., Ramonetti, J.T., Abreu-Goris, M., Newmark, H.L., Lipkin, M.L., DeCosse, J.J., and Bertagnolli, M.M. (1996). Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. Cancer Res. 56, 2556-2560.
-
(1996)
Cancer Res.
, vol.56
, pp. 2556-2560
-
-
Boolbol, S.K.1
Dannenberg, A.J.2
Chadburn, A.3
Martucci, C.4
Guo, X.J.5
Ramonetti, J.T.6
Abreu-Goris, M.7
Newmark, H.L.8
Lipkin, M.L.9
DeCosse, J.J.10
Bertagnolli, M.M.11
-
2
-
-
0026591034
-
Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers
-
Boynton, R.F. Blount, P.L., Yin, J., Brown, V.L., Huang, Y., Tong, Y., McDaniel, T., Newkirk, C., Resau, J.H., Raskind, W.H., et al. (1992). Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers. Proc. Natl. Acad. Sci. USA 89, 3385-3388.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3385-3388
-
-
Boynton, R.F.1
Blount, P.L.2
Yin, J.3
Brown, V.L.4
Huang, Y.5
Tong, Y.6
McDaniel, T.7
Newkirk, C.8
Resau, J.H.9
Raskind, W.H.10
-
3
-
-
0023968630
-
Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
-
DeWitt, D.L. and Smith, W.L. (1988). Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc. Natl. Acad. Sci. USA 85, 1412-1416.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1412-1416
-
-
DeWitt, D.L.1
Smith, W.L.2
-
4
-
-
0027363063
-
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
-
Dietrich, W.F., Lander, E.S., Smith, J.S., Moser, A.R., Gould, D.A., Luongo, C., Borenstein, N., and Dove, W. (1993). Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 75, 631-639.
-
(1993)
Cell
, vol.75
, pp. 631-639
-
-
Dietrich, W.F.1
Lander, E.S.2
Smith, J.S.3
Moser, A.R.4
Gould, D.A.5
Luongo, C.6
Borenstein, N.7
Dove, W.8
-
5
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk, J.E., Car, B.D., Focht, R.J., Johnston, J.J., Jaffee, B. D., Covington, M.B., Contel, N.R., Eng, V.M., Collins, R.J., Czerniak, P.M., et al. (1995). Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 378, 406-409.
-
(1995)
Nature
, vol.378
, pp. 406-409
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
Johnston, J.J.4
Jaffee, B.D.5
Covington, M.B.6
Contel, N.R.7
Eng, V.M.8
Collins, R.J.9
Czerniak, P.M.10
-
6
-
-
0029913633
-
Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors
-
DuBois, R.N., Radhika, A., Reddy, B.S., and Entingh, A.J. (1996). Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterol. 110, 1259-1262.
-
(1996)
Gastroenterol.
, vol.110
, pp. 1259-1262
-
-
DuBois, R.N.1
Radhika, A.2
Reddy, B.S.3
Entingh, A.J.4
-
7
-
-
0028344102
-
Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-α and phorbol ester
-
DuBois, R.N., Awad, J., Morrow, J., Roberts, L.J., and Bishop, P.R. (1994). Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-α and phorbol ester. J. Clin. Invest. 93, 493-496.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 493-496
-
-
DuBois, R.N.1
Awad, J.2
Morrow, J.3
Roberts, L.J.4
Bishop, P.R.5
-
8
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
-
Eberhart, G.E., Coffey, R.J., Radhika, A., Giardiello, F.M., Ferrenbach, S., and DuBois, R.N. (1994). Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterol. 107, 1183-1188.
-
(1994)
Gastroenterol.
, vol.107
, pp. 1183-1188
-
-
Eberhart, G.E.1
Coffey, R.J.2
Radhika, A.3
Giardiello, F.M.4
Ferrenbach, S.5
Dubois, R.N.6
-
9
-
-
0027197062
-
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
-
Giardiello, F.M., Hamilton, S.R., Krush, A.J., Piantadosi, S., Hylind, L.M., Celano, P., Booker, S.V., Robinson, C.R., and Offerhaus, G.J.A. (1993). Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. New Engl. J. Med. 328, 1313-1316.
-
(1993)
New Engl. J. Med.
, vol.328
, pp. 1313-1316
-
-
Giardiello, F.M.1
Hamilton, S.R.2
Krush, A.J.3
Piantadosi, S.4
Hylind, L.M.5
Celano, P.6
Booker, S.V.7
Robinson, C.R.8
Offerhaus, G.J.A.9
-
10
-
-
0017094438
-
Purification of the cyclooxygenase that forms prostaglandins
-
Hemler, M., and Lands, W.E.M. (1976). Purification of the cyclooxygenase that forms prostaglandins. J. Biol. Chem. 251, 5575-5579.
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 5575-5579
-
-
Hemler, M.1
Lands, W.E.M.2
-
11
-
-
0026734665
-
The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer
-
Horii, A., Nakatsuru, S., Miyoshi, Y., Ichii, S., Nagase, H., Kato, Y., Yanagisawa, A., and Nakamura, Y. (1992). The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res. 52, 3231-3233.
-
(1992)
Cancer Res.
, vol.52
, pp. 3231-3233
-
-
Horii, A.1
Nakatsuru, S.2
Miyoshi, Y.3
Ichii, S.4
Nagase, H.5
Kato, Y.6
Yanagisawa, A.7
Nakamura, Y.8
-
12
-
-
0029008617
-
Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
-
Kargman, S.L., O'Neill, G.P., Vickers, P.J., Evans, J.F., Mancini, J.A., and Jothy, S. (1995). Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res. 55, 2556-2559.
-
(1995)
Cancer Res.
, vol.55
, pp. 2556-2559
-
-
Kargman, S.L.1
O'Neill, G.P.2
Vickers, P.J.3
Evans, J.F.4
Mancini, J.A.5
Jothy, S.6
-
13
-
-
0030580035
-
Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells
-
in press
-
Kargman, S., Wong, E., Greig, G.M., Falgueyret, J.-P., Cromlish, W., Ethier, D., Yergey, J.A., Riendeau, D., Evans, J.F., Kennedy, B., et al. (1996). Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells. Biochem. Pharmacol., in press.
-
(1996)
Biochem. Pharmacol.
-
-
Kargman, S.1
Wong, E.2
Greig, G.M.3
Falgueyret, J.-P.4
Cromlish, W.5
Ethier, D.6
Yergey, J.A.7
Riendeau, D.8
Evans, J.F.9
Kennedy, B.10
-
14
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird, P.W., Jackson-Grusby, L., Faseli, A., Dickinson, S.L., Jung, W.E., Li, E., Weinberg, R.A., and Jaenisch, R. (1995). Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81, 197-205.
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Faseli, A.3
Dickinson, S.L.4
Jung, W.E.5
Li, E.6
Weinberg, R.A.7
Jaenisch, R.8
-
15
-
-
0027076645
-
Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide
-
Lee, S.H., Soyoola, E., Chanmugam, P., Hart, S., Sun, W., Zhong, H., Liou, S., Simmons, D., and Hwang, D. (1992). Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J. Biol. Chem. 267, 25934-25938.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25934-25938
-
-
Lee, S.H.1
Soyoola, E.2
Chanmugam, P.3
Hart, S.4
Sun, W.5
Zhong, H.6
Liou, S.7
Simmons, D.8
Hwang, D.9
-
16
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E., Bestor, T.H., and Jaenisch, R., (1992). Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
18
-
-
0025365504
-
Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells
-
Maier, J.A.M., Hla, T. and Maciag, H. (1990). Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. J. Biol. Chem. 265, 10805-10808.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 10805-10808
-
-
Maier, J.A.M.1
Hla, T.2
Maciag, H.3
-
19
-
-
0026761738
-
Aspirin and the potential role of prostaglandins in colon cancer
-
Marnett, L.J. (1992). Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res. 52, 5575-5589.
-
(1992)
Cancer Res.
, vol.52
, pp. 5575-5589
-
-
Marnett, L.J.1
-
20
-
-
0027480087
-
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal antiinflammatory drugs
-
Meade, E.A., Smith, W.L., and DeWitt, D.L. (1993). Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal antiinflammatory drugs. J. Biol. Chem. 268, 6610-6614.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6610-6614
-
-
Meade, E.A.1
Smith, W.L.2
DeWitt, D.L.3
-
21
-
-
0027146692
-
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
-
Mitchell, J.A., Akarasereenont, P., Thiemermann, C., Flower, R.J., and Vane, J.R. (1994). Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. USA 90, 11693-11697.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11693-11697
-
-
Mitchell, J.A.1
Akarasereenont, P.2
Thiemermann, C.3
Flower, R.J.4
Vane, J.R.5
-
22
-
-
0017070560
-
Purification of prostaglandin endoperoxide synthase from bovine vesicular gland microsomes
-
Miyamoto, T., Ogino, N., Yamamoto, S., and Hayaishi, O. (1976). Purification of prostaglandin endoperoxide synthase from bovine vesicular gland microsomes. J. Biol. Chem. 251, 2629-2636.
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 2629-2636
-
-
Miyamoto, T.1
Ogino, N.2
Yamamoto, S.3
Hayaishi, O.4
-
23
-
-
0028807498
-
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
-
Morham, S.G., Langenbach, R., Loftin, C.D., Tiano, H.F., Vouloumanos, N., Jennette, J.C., Mahler, J.F., Kluckman, K.D., Ledford, A., Lee, C. A., and Smithies, O. (1995). Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 83, 473-482.
-
(1995)
Cell
, vol.83
, pp. 473-482
-
-
Morham, S.G.1
Langenbach, R.2
Loftin, C.D.3
Tiano, H.F.4
Vouloumanos, N.5
Jennette, J.C.6
Mahler, J.F.7
Kluckman, K.D.8
Ledford, A.9
Lee, C.A.10
Smithies, O.11
-
24
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser, A.R., Pitot, H.C., and Dove, W.F. (1990). A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322-324.
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
25
-
-
0026735231
-
cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
-
O'Banion, M.K., Winn, V.D., and Young, D.A. (1992). cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA 89, 4888-4892.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4888-4892
-
-
O'Banion, M.K.1
Winn, V.D.2
Young, D.A.3
-
26
-
-
0027293391
-
Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
-
O'Neill, G.P., and Ford-Hutchinson, A.W. (1993). Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett. 330, 156-160.
-
(1993)
FEBS Lett.
, vol.330
, pp. 156-160
-
-
O'Neill, G.P.1
Ford-Hutchinson, A.W.2
-
27
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima, M., Oshima, H., Kitagawa, K., Kobayashi, M., Itakura, C., and Taketo, M. (1995a). Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc. Natl. Acad. Sci. USA 92, 4482-4486.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
Kobayashi, M.4
Itakura, C.5
Taketo, M.6
-
28
-
-
0028794084
-
Δ716 knockout mice
-
Δ716 knockout mice. Carcinogenesis 16, 2605-2607.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2605-2607
-
-
Oshima, M.1
Takahashi, M.2
Oshima, H.3
Tsutsumi, M.4
Yazawa, K.5
Sugimura, T.6
Nishimura, S.7
Wakabayashi, K.8
Taketo, M.M.9
-
29
-
-
0030003582
-
Δ716 knockout mice
-
Δ716 knockout mice. Mol. Carcinogen. 15, 11-17.
-
(1996)
Mol. Carcinogen.
, vol.15
, pp. 11-17
-
-
Oshima, M.1
Oshima, H.2
Tsutsumi, M.3
Nishimura, S.4
Sugimura, T.5
Nagao, M.6
Taketo, M.M.7
-
30
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell, S.M., Zilz, N., Beazer-Barclay, Y., Bryan, T.M., Hamilton, S.R., Thibodeau, S.N., Vogelstein, B., and Kinzler, K.W. (1992). APC mutations occur early during colorectal tumorigenesis. Nature 359, 235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
31
-
-
0028904461
-
Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent
-
Rao, C.V., Rivernson, A., Simi, B., Zang, E., Kelloff, G., Steele, V., and Reddy, B.S. (1995). Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. Cancer Res. 55, 1464-1472.
-
(1995)
Cancer Res.
, vol.55
, pp. 1464-1472
-
-
Rao, C.V.1
Rivernson, A.2
Simi, B.3
Zang, E.4
Kelloff, G.5
Steele, V.6
Reddy, B.S.7
-
32
-
-
0027183769
-
Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats
-
Reddy, B.S., Rao, C.V., Rivenson, A., and Kelloff, G. (1993). Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats. Carcinogenesis 14, 1493-1497.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1493-1497
-
-
Reddy, B.S.1
Rao, C.V.2
Rivenson, A.3
Kelloff, G.4
-
33
-
-
0027371123
-
Altered eicosanoid levels in human colon cancer
-
Rigas, B., Goldman, I.S., and Levine, L. (1993). Altered eicosanoid levels in human colon cancer. J. Lab. Clin. Med. 122, 518-523.
-
(1993)
J. Lab. Clin. Med.
, vol.122
, pp. 518-523
-
-
Rigas, B.1
Goldman, I.S.2
Levine, L.3
-
34
-
-
0026562404
-
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
-
Su, L.K., Kinzler, K.W., Vogelstein, B., Preisinger, A.C., Moser, A.R., Luongo, C., Gould, K.A., and Dove, W.F. (1992). Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 250, 668-670.
-
(1992)
Science
, vol.250
, pp. 668-670
-
-
Su, L.K.1
Kinzler, K.W.2
Vogelstein, B.3
Preisinger, A.C.4
Moser, A.R.5
Luongo, C.6
Gould, K.A.7
Dove, W.F.8
-
35
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
Tsujii, M., and DuBois, R.N. (1995). Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83, 493-501.
-
(1995)
Cell
, vol.83
, pp. 493-501
-
-
Tsujii, M.1
DuBois, R.N.2
-
36
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane, J.R. (1971). Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol. 231, 232-235.
-
(1971)
Nature New Biol.
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
37
-
-
0028044609
-
Towards a better aspirin
-
Vane, J. (1994). Towards a better aspirin. Nature 367, 215-216.
-
(1994)
Nature
, vol.367
, pp. 215-216
-
-
Vane, J.1
-
38
-
-
0029839213
-
Elevated cyclooxygenase-2 levels in Min mouse adenomas
-
Williams, C.W., Luongo, C., Radhika, A., Zhang, T., Lamps, L.W., Nanney, L.B., Beauchamp, R.D., and DuBois, R.N. (1996). Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterol. 110, 1134-1140.
-
(1996)
Gastroenterol.
, vol.110
, pp. 1134-1140
-
-
Williams, C.W.1
Luongo, C.2
Radhika, A.3
Zhang, T.4
Lamps, L.W.5
Nanney, L.B.6
Beauchamp, R.D.7
Dubois, R.N.8
-
39
-
-
0026588961
-
Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs
-
Xie, W., Robertson, D.L., and Simmons, D.L. (1992). Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs. Drug Dev. Res. 25, 249-265.
-
(1992)
Drug Dev. Res.
, vol.25
, pp. 249-265
-
-
Xie, W.1
Robertson, D.L.2
Simmons, D.L.3
|