Molecular and functional characterization of polymorphisms in the secreted phospholipase A2 group X gene: Relevance to coronary artery disease

Journal of Molecular Medicine

Volumn 87, Issue 7, 2009, Pages 723-733

  Gora, Sarah ^a   Perret, Claire ^a   Jemel, Ikram ^b   Nicaud, Viviane ^a   Lambeau, Gérard ^b   Cambien, François ^a   Ninio, Ewa ^a   Blankenberg, Stefan ^c   Tiret, Laurence ^a   Karabina, Sonia Athina ^a  

^a INSERM   (France)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

CAD; HGX sPLA2; PLA2G10; Polymorphisms; Secreted phospholipase A2

Indexed keywords

PHOSPHOLIPASE A2;

5' UNTRANSLATED REGION; ADULT; AGED; ANIMAL CELL; ARTICLE; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CELL STRAIN COS7; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ENZYME ACTIVITY; ENZYME POLYMORPHISM; FEMALE; GENE; GENETIC ASSOCIATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PLA2G10 GENE; SITE DIRECTED MUTAGENESIS;

5' UNTRANSLATED REGIONS; ADULT; AGED; CORONARY ARTERY DISEASE; FEMALE; FLUOROIMMUNOASSAY; GENETIC PREDISPOSITION TO DISEASE; GROUP X PHOSPHOLIPASES A2; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; MUTAGENESIS, SITE-DIRECTED; POLYMORPHISM, GENETIC;

EID: 67649424740     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-009-0483-y     Document Type: Article

References (31)

1. K Kugiyama Y Ota K Takazoe Y Moriyama H Kawano Y Miyao T Sakamoto H Soejima H Ogawa H Doi S Sugiyama H Yasue 1999 Circulating levels of secretory type II phospholipase A(2) predict coronary events in patients with coronary artery disease Circulation 100 1280 1284 (Pubitemid 29440119)
2. SA Karabina I Brocheriou G Le Naour M Agrapart H Durand M Gelb G Lambeau E Ninio 2006 Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function FASEB J 20 2547 2549
3. B Rosengren AC Jonsson-Rylander H Peilot G Camejo E Hurt-Camejo 2006 Distinctiveness of secretory phospholipase A2 group IIA and V suggesting unique roles in atherosclerosis Biochim Biophys Acta 1761 1301 1308 (Pubitemid 44768005)
4. H Sato R Kato Y Isogai GI Saka M Ohtsuki Y Taketomi K Yamamoto K Tsutsumi J Yamada S Masuda Y Ishikawa T Ishii T Kobayashi K Ikeda R Taguchi S Hatakeyama S Hara I Kudo H Itabe M Murakami 2008 Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis J Biol Chem 283 33483 33497
5. CR Wooton-Kee BB Boyanovsky MS Nasser WJ de Villiers NR Webb 2004 Group V sPLA2 hydrolysis of low-density lipoprotein results in spontaneous particle aggregation and promotes macrophage foam cell formation Arterioscler Thromb Vasc Biol 24 762 767 (Pubitemid 38451617)
6. G Lambeau MH Gelb 2008 Biochemistry and physiology of mammalian secreted phospholipases A2 Annu Rev Biochem 77 495 520
7. MA Bostrom BB Boyanovsky CT Jordan MP Wadsworth DJ Taatjes FC de Beer NR Webb 2007 Group V secretory phospholipase A2 promotes atherosclerosis: evidence from genetically altered mice Arterioscler Thromb Vasc Biol 27 600 606 (Pubitemid 46263406)
8. DM Curfs SA Ghesquiere MN Vergouwe I van der Made MJ Gijbels DR Greaves JS Verbeek MH Hofker MP de Winther 2008 Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology J Biol Chem 283 21640 21648
9. WR Henderson Jr EY Chi JG Bollinger YT Tien X Ye L Castelli YP Rubtsov AG Singer GK Chiang T Nevalainen AY Rudensky MH Gelb 2007 Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model J Exp Med 204 865 877 (Pubitemid 46631615)
10. M Ohtsuki Y Taketomi S Arata S Masuda Y Ishikawa T Ishii Y Takanezawa J Aoki H Arai K Yamamoto I Kudo M Murakami 2006 Transgenic expression of group V, but not group X, secreted phospholipase A2 in mice leads to neonatal lethality because of lung dysfunction J Biol Chem 281 36420 36433 (Pubitemid 46041376)
11. D Fujioka Y Saito T Kobayashi T Yano H Tezuka Y Ishimoto N Suzuki Y Yokota T Nakamura JE Obata M Kanazawa K Kawabata K Hanasaki K Kugiyama 2008 Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice Circulation 117 2977 2985
12. S Masuda M Murakami M Mitsuishi K Komiyama Y Ishikawa T Ishii I Kudo 2005 Expression of secretory phospholipase A2 enzymes in lungs of humans with pneumonia and their potential prostaglandin-synthetic function in human lung-derived cells Biochem J 387 27 38 (Pubitemid 40524071)
13. Y Morioka M Ikeda A Saiga N Fujii Y Ishimoto H Arita K Hanasaki 2000 Potential role of group X secretory phospholipase A(2) in cyclooxygenase-2- dependent PGE(2) formation during colon tumorigenesis FEBS Lett 487 262 266 (Pubitemid 32057123)
14. L Cupillard K Koumanov MG Mattei M Lazdunski G Lambeau 1997 Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2 J Biol Chem 272 15745 15752 (Pubitemid 27265549)
15. S Bezzine JG Bollinger AG Singer SL Veatch SL Keller MH Gelb 2002 On the binding preference of human groups IIA and X phospholipases A2 for membranes with anionic phospholipids J Biol Chem 277 48523 48534 (Pubitemid 35470813)
16. S Gora G Lambeau JG Bollinger M Gelb E Ninio SA Karabina 2006 The proinflammatory mediator platelet activating factor is an effective substrate for human group X secreted phospholipase A2 Biochim Biophys Acta 1761 1093 1099 (Pubitemid 44354298)
17. K Hanasaki K Yamada S Yamamoto Y Ishimoto A Saiga T Ono M Ikeda M Notoya S Kamitani H Arita 2002 Potent modification of low density lipoprotein by group X secretory phospholipase A2 is linked to macrophage foam cell formation J Biol Chem 277 29116 29124
18. W Pruzanski L Lambeau M Lazdunsky W Cho J Kopilov A Kuksis 2005 Differential hydrolysis of molecular species of lipoprotein phosphatidylcholine by groups IIA, V and X secretory phospholipases A(2) Biochim Biophys Acta 1736 38 50 (Pubitemid 41208258)
19. HJ Parra D Arveiler AE Evans JP Cambou P Amouyel A Bingham D McMaster P Schaffer P Douste-Blazy G Luc 1992 A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease. The ECTIM study Arterioscler Thromb 12 701 707
20. HJ Rupprecht S Blankenberg C Bickel G Rippin G Hafner W Prellwitz W Schlumberger J Meyer 2001 Impact of viral and bacterial infectious burden on long-term prognosis in patients with coronary artery disease Circulation 104 25 31 (Pubitemid 32623285)
21. L Tiret T Godefroy E Lubos V Nicaud DA Tregouet S Barbaux R Schnabel C Bickel C Espinola-Klein O Poirier C Perret T Munzel HJ Rupprecht K Lackner F Cambien S Blankenberg 2005 Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease Circulation 112 643 650 (Pubitemid 41099042)
22. DA Tregouet S Barbaux S Escolano N Tahri JL Golmard L Tiret F Cambien 2002 Specific haplotypes of the P-selectin gene are associated with myocardial infarction Hum Mol Genet 11 2015 2023 (Pubitemid 34919276)
23. TJ Nevalainen LI Eerola E Rintala VJ Laine G Lambeau MH Gelb 2005 Time-resolved fluoroimmunoassays of the complete set of secreted phospholipases A2 in human serum Biochim Biophys Acta 1733 210 223 (Pubitemid 40603664)
24. M Rouault C Le Calvez E Boilard F Surrel A Singer F Ghomashchi S Bezzine S Scarzello J Bollinger MH Gelb G Lambeau 2007 Recombinant production and properties of binding of the full set of mouse secreted phospholipases A2 to the mouse M-type receptor Biochemistry 46 1647 1662 (Pubitemid 46259314)
25. M Rouault LD Rash P Escoubas E Boilard J Bollinger B Lomonte T Maurin C Guillaume S Canaan C Deregnaucourt J Schrevel A Doglio JM Gutierrez M Lazdunski MH Gelb G Lambeau 2006 Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity Biochemistry 45 5800 5816
26. V Bernier M Lagace DG Bichet M Bouvier 2004 Pharmacological chaperones: potential treatment for conformational diseases Trends Endocrinol Metab 15 222 228 (Pubitemid 38833993)
27. CM Mounier D Wendum E Greenspan JF Flejou DW Rosenberg G Lambeau 2008 Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate Br J Cancer 98 587 595 (Pubitemid 351214519)
28. Z Mallat PG Steg J Benessiano ML Tanguy KA Fox JP Collet OH Dabbous P Henry KF Carruthers A Dauphin CS Arguelles J Masliah B Hugel G Montalescot JM Freyssinet B Asselain A Tedgui 2005 Circulating secretory phospholipase A2 activity predicts recurrent events in patients with severe acute coronary syndromes J Am Coll Cardiol 46 1249 1257 (Pubitemid 41615545)
29. PT Wootton NL Arora F Drenos SR Thompson JA Cooper JW Stephens SJ Hurel E Hurt-Camejo O Wiklund SE Humphries PJ Talmud 2007 Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study Hum Mol Genet 16 1437 1444 (Pubitemid 47061339)
30. PT Wootton F Drenos JA Cooper SR Thompson JW Stephens E Hurt-Camejo O Wiklund SE Humphries PJ Talmud 2006 Tagging-SNP haplotype analysis of the secretory PLA2IIa gene PLA2G2A shows strong association with serum levels of sPLA2IIa: results from the UDACS study Hum Mol Genet 15 355 361 (Pubitemid 43125989)
31. S Masuda M Murakami Y Takanezawa J Aoki H Arai Y Ishikawa T Ishii M Arioka I Kudo 2005 Neuronal expression and neuritogenic action of group X secreted phospholipase A2 J Biol Chem 280 23203 23214 (Pubitemid 40853232)