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Volumn 30, Issue 2, 2010, Pages 313-320

Phospholipase A2-modified low-density lipoprotein activates macrophage peroxisome proliferator-activated receptors

Author keywords

Atherosclerosis; Low density lipoprotein; Peroxisome proliferator activated receptors; Phagocytes; Phospholipase A2

Indexed keywords

ADIPOPHILIN; CHOLESTEROL; CXCL9 CHEMOKINE; FAT DROPLET; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 12; INTERLEUKIN 6; LAMIN; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN; LUCIFERASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SECRETORY PHOSPHOLIPASE A2; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 75149162437     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.199232     Document Type: Article
Times cited : (15)

References (42)
  • 1
    • 0036852744 scopus 로고    scopus 로고
    • The macrophage foam cell as a target for therapeutic intervention
    • Li AC, Glass CK. The macrophage foam cell as a target for therapeutic intervention. Nat Med. 2002;8:1235-1242.
    • (2002) Nat Med , vol.8 , pp. 1235-1242
    • Li, A.C.1    Glass, C.K.2
  • 2
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;352:1685-1695.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 3
    • 10044223533 scopus 로고    scopus 로고
    • PPAR-and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
    • Li AC, Glass CK. PPAR-and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res. 2004; 45:2161-2173.
    • (2004) J Lipid Res , vol.45 , pp. 2161-2173
    • Li, A.C.1    Glass, C.K.2
  • 4
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 1998;93:229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 6
    • 0034665060 scopus 로고    scopus 로고
    • Role for per-oxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells
    • Lee H, Shi W, Tontonoz P, Wang S, Subbanagounder G, Hedrick CC, Hama S, Borromeo C, Evans RM, Berliner JA, Nagy L. Role for per-oxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circ Res. 2000;87:516-521.
    • (2000) Circ Res , vol.87 , pp. 516-521
    • Lee, H.1    Shi, W.2    Tontonoz, P.3    Wang, S.4    Subbanagounder, G.5    Hedrick, C.C.6    Hama, S.7    Borromeo, C.8    Evans, R.M.9    Berliner, J.A.10    Nagy, L.11
  • 9
    • 33645298823 scopus 로고    scopus 로고
    • High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: A candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion
    • Ahmed W, Orasanu G, Nehra V, Asatryan L, Rader DJ, Ziouzenkova O, Plutzky J. High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion. Circ Res. 2006;98:490-498.
    • (2006) Circ Res , vol.98 , pp. 490-498
    • Ahmed, W.1    Orasanu, G.2    Nehra, V.3    Asatryan, L.4    Rader, D.J.5    Ziouzenkova, O.6    Plutzky, J.7
  • 12
    • 36049034344 scopus 로고    scopus 로고
    • Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms
    • Straus DS, Glass CK. Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol. 2007; 28:551-558.
    • (2007) Trends Immunol , vol.28 , pp. 551-558
    • Straus, D.S.1    Glass, C.K.2
  • 18
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol. 2005;5:953-964.
    • (2005) Nat Rev Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 20
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
    • Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, Lee CH. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab. 2008;7:485-495.
    • (2008) Cell Metab , vol.7 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3    Gangl, M.R.4    Fitzgerald, K.5    Hatano, B.6    Lee, C.H.7
  • 23
    • 1842475761 scopus 로고    scopus 로고
    • Group v sPLA2 hydrolysis of low-density lipoprotein results in spontaneous particle aggregation and promotes macrophage foam cell formation
    • Wooton-Kee CR, Boyanovsky BB, Nasser MS, de Villiers WJ, Webb NR. Group V sPLA2 hydrolysis of low-density lipoprotein results in spontaneous particle aggregation and promotes macrophage foam cell formation. Arterioscler Thromb Vasc Biol. 2004;24:762-767.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 762-767
    • Wooton-Kee, C.R.1    Boyanovsky, B.B.2    Nasser, M.S.3    De Villiers, W.J.4    Webb, N.R.5
  • 24
    • 19044392084 scopus 로고    scopus 로고
    • Potent modification of low density lipoprotein by group X secretory phospholipase A2 is linked to macro-phage foam cell formation
    • Hanasaki K, Yamada K, Yamamoto S, Ishimoto Y, Saiga A, Ono T, Ikeda M, Notoya M, Kamitani S, Arita H. Potent modification of low density lipoprotein by group X secretory phospholipase A2 is linked to macro-phage foam cell formation. J Biol Chem. 2002;277:29116-29124.
    • (2002) J Biol Chem , vol.277 , pp. 29116-29124
    • Hanasaki, K.1    Yamada, K.2    Yamamoto, S.3    Ishimoto, Y.4    Saiga, A.5    Ono, T.6    Ikeda, M.7    Notoya, M.8    Kamitani, S.9    Arita, H.10
  • 25
    • 23444442916 scopus 로고    scopus 로고
    • Secretory phospholipase A2 enzymes in atherogenesis
    • Webb NR. Secretory phospholipase A2 enzymes in atherogenesis. Curr Opin Lipidol. 2005;16:341-344.
    • (2005) Curr Opin Lipidol , vol.16 , pp. 341-344
    • Webb, N.R.1
  • 26
    • 23044484743 scopus 로고    scopus 로고
    • The role of phospholipases in lipid modification and atherosclerosis
    • Ghesquiere SA, Hofker MH, de Winther MP. The role of phospholipases in lipid modification and atherosclerosis. Cardiovasc Toxicol. 2005;5: 161-182.
    • (2005) Cardiovasc Toxicol , vol.5 , pp. 161-182
    • Ghesquiere, S.A.1    Hofker, M.H.2    De Winther, M.P.3
  • 27
    • 33750215165 scopus 로고    scopus 로고
    • Phospholipase A2-modified low-density lipoprotein activates the phosphatidylinositol 3-kinase-Akt pathway and increases cell survival in monocytic cells
    • Namgaladze D, Brüne B. Phospholipase A2-modified low-density lipoprotein activates the phosphatidylinositol 3-kinase-Akt pathway and increases cell survival in monocytic cells. Arterioscler Thromb Vasc Biol. 2006;26:2510-2516.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2510-2516
    • Namgaladze, D.1    Brüne, B.2
  • 28
    • 33746931148 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism
    • Ulrich S, Loitsch SM, Rau O, von Knethen A, Brüne B, Schubert-Zsilavecz M, Stein JM. Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism. Cancer Res. 2006;66:7348-7354.
    • (2006) Cancer Res , vol.66 , pp. 7348-7354
    • Ulrich, S.1    Loitsch, S.M.2    Rau, O.3    Von Knethen, A.4    Brüne, B.5    Schubert-Zsilavecz, M.6    Stein, J.M.7
  • 29
    • 33845678939 scopus 로고    scopus 로고
    • Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function
    • Karabina SA, Brochériou I, Le Naour G, Agrapart M, Durand H, Gelb M, Lambeau G, Ninio E. Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function. FASEB J. 2006;20:2547-2549.
    • (2006) FASEB J , vol.20 , pp. 2547-2549
    • Karabina, S.A.1    Brochériou, I.2    Le Naour, G.3    Agrapart, M.4    Durand, H.5    Gelb, M.6    Lambeau, G.7    Ninio, E.8
  • 30
    • 0345593601 scopus 로고    scopus 로고
    • Lipolytic modification of LDL by phospholipase A2 induces particle aggregation in the absence and fusion in the presence of heparin
    • Hakala JK, Oörni K, Ala-Korpela M, Kovanen PT. Lipolytic modification of LDL by phospholipase A2 induces particle aggregation in the absence and fusion in the presence of heparin. Arterioscler Thromb Vasc Biol. 1999;19:1276-1283.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1276-1283
    • Hakala, J.K.1    Oörni, K.2    Ala-Korpela, M.3    Kovanen, P.T.4
  • 31
    • 0037022592 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling
    • Shi Y, Hon M, Evans RM. The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling. Proc Natl Acad Sci USA. 2002;99:2613-2618.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2613-2618
    • Shi, Y.1    Hon, M.2    Evans, R.M.3
  • 32
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8:958-969.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 33
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • Martinez FO, Gordon S, Locati M, Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol. 2006;177:7303-7311.
    • (2006) J Immunol , vol.177 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 34
    • 0034693323 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B
    • Chung SW, Kang BY, Kim SH, Pak YK, Cho D, Trinchieri G, Kim TS. Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B. J Biol Chem. 2000;275:32681-32687.
    • (2000) J Biol Chem , vol.275 , pp. 32681-32687
    • Chung, S.W.1    Kang, B.Y.2    Kim, S.H.3    Pak, Y.K.4    Cho, D.5    Trinchieri, G.6    Kim, T.S.7
  • 35
    • 0037087449 scopus 로고    scopus 로고
    • Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: Role of peroxisome proliferator-activated receptor-gamma
    • Fischer B, von Knethen A, Brüne B. Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma. J Immunol. 2002;168: 2828-2834.
    • (2002) J Immunol , vol.168 , pp. 2828-2834
    • Fischer, B.1    Von Knethen, A.2    Brüne, B.3
  • 36
    • 0001538199 scopus 로고    scopus 로고
    • Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma
    • Han KH, Chang MK, Boullier A, Green SR, Li A, Glass CK, Quehen-berger O. Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. J Clin Invest. 2000;106:793-802.
    • (2000) J Clin Invest , vol.106 , pp. 793-802
    • Han, K.H.1    Chang, M.K.2    Boullier, A.3    Green, S.R.4    Li, A.5    Glass, C.K.6    Quehen-Berger, O.7
  • 37
    • 33144455156 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage
    • Lee CH, Kang K, Mehl IR, Nofsinger R, Alaynick WA, Chong LW, Rosenfeld JM, Evans RM. Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage. Proc Natl Acad Sci USA. 2006;103:2434-2439.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2434-2439
    • Lee, C.H.1    Kang, K.2    Mehl, I.R.3    Nofsinger, R.4    Alaynick, W.A.5    Chong, L.W.6    Rosenfeld, J.M.7    Evans, R.M.8
  • 38
    • 34547597709 scopus 로고    scopus 로고
    • PPARalpha in atherosclerosis and inflammation
    • Zandbergen F, Plutzky J. PPARalpha in atherosclerosis and inflammation. Biochim Biophys Acta. 2007;1771:972-982.
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 972-982
    • Zandbergen, F.1    Plutzky, J.2
  • 40
    • 70350366595 scopus 로고    scopus 로고
    • Triglyceride alters lysosomal cholesterol metabolism in cholesteryl ester-laden macrophage foam cells
    • Ullery-Ricewick JC, Cox BE, Griffin EE, Jerome WG. Triglyceride alters lysosomal cholesterol metabolism in cholesteryl ester-laden macrophage foam cells. J Lipid Res. 2009;50:2014-2026.
    • (2009) J Lipid Res , vol.50 , pp. 2014-2026
    • Ullery-Ricewick, J.C.1    Cox, B.E.2    Griffin, E.E.3    Jerome, W.G.4
  • 41
    • 48249100857 scopus 로고    scopus 로고
    • Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis
    • Paul A, Chang BH, Li L, Yechoor VK, Chan L. Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis. Circ Res. 2008;102:1492-1501.
    • (2008) Circ Res , vol.102 , pp. 1492-1501
    • Paul, A.1    Chang, B.H.2    Li, L.3    Yechoor, V.K.4    Chan, L.5
  • 42
    • 30044445455 scopus 로고    scopus 로고
    • Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway
    • Xu G, Sztalryd C, Lu X, Tansey JT, Gan J, Dorward H, Kimmel AR, Londos C. Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway. J Biol Chem. 2005;280: 42841-42847.
    • (2005) J Biol Chem , vol.280 , pp. 42841-42847
    • Xu, G.1    Sztalryd, C.2    Lu, X.3    Tansey, J.T.4    Gan, J.5    Dorward, H.6    Kimmel, A.R.7    Londos, C.8


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