A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

Diabetologia

Volumn 52, Issue 6, 2009, Pages 1056-1060

  Kotronen, A ^a,b   Johansson, L E ^c   Johansson, L M ^c   Roos, C ^c   Westerbacka, J ^a   Hamsten, A ^d   Bergholm, R ^a,b   Arkkila, P ^a   Arola, J ^a   Kiviluoto, T ^a   Fisher, R M ^d   Ehrenborg, E ^d   Orho Melander, M ^c   Ridderstrale M ^c   Groop, L ^c   Yki Jarvinen H ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adiponutrin; Adipose tissue insulin sensitivity; Gene expression; Hepatic insulin sensitivity; Liver enzymes; Non alcoholic fatty liver disease; Rs738409

Indexed keywords

ADIPONUTRIN; ASPARTATE AMINOTRANSFERASE; CYTOKINE; MESSENGER RNA; TRITIUM; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ADULT; AGED; ALLELE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY MASS; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA POLYMORPHISM; ETHNIC GROUP; EUROPEAN AMERICAN; FAT CONTENT; FATTY LIVER; FEMALE; FINLAND; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; GENOTYPE; GLUCOSE INFUSION; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIVER; MAJOR CLINICAL STUDY; MALE; OBESITY; PATCH CLAMP; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; BODY MASS INDEX; FATTY LIVER; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUCOSE CLAMP TECHNIQUE; HUMANS; LIPASE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMBRANE PROTEINS; MIDDLE AGED; OBESITY; POLYMERASE CHAIN REACTION;

EID: 67349174005     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1285-z     Document Type: Article

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