iPLA2β: Front and center in human monocyte chemotaxis to MCP-1

Journal of Experimental Medicine

Volumn 205, Issue 2, 2008, Pages 347-359

  Mishra, Ravi S ^a   Carnevale, Kevin A ^b   Cathcart, Martha K ^a,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CALCIUM; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHOLIPASE A2; 6 (BROMOMETHYLENE)TETRAHYDRO 3 (1 NAPHTHALENEYL) 2H PYRAN 2 ONE; 6-(BROMOMETHYLENE)TETRAHYDRO-3-(1-NAPHTHALENEYL)-2H-PYRAN-2-ONE; ACTIN; ARACHIDONIC ACID DERIVATIVE; ARACHIDONYLTRIFLUOROMETHANE; CCL2 PROTEIN, HUMAN; NAPHTHALENE DERIVATIVE; PHOSPHOLIPASE A2 GROUP IV; PHOSPHOLIPASE A2 GROUP VI; PLA2G6 PROTEIN, HUMAN; PYRONE DERIVATIVE; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ADOPTIVE TRANSFER; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL FUNCTION; CELL MIGRATION; CELL STIMULATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; IMMUNE RESPONSE; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM; PRIORITY JOURNAL; PSEUDOPODIUM; SIGNAL TRANSDUCTION; SYSTEMATIC REVIEW; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; PERITONITIS;

ACTINS; ADOPTIVE TRANSFER; ANIMALS; ARACHIDONIC ACIDS; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOTAXIS; FEMALE; GROUP IV PHOSPHOLIPASES A2; GROUP VI PHOSPHOLIPASES A2; HUMANS; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED BALB C; MONOCYTES; NAPHTHALENES; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PERITONITIS; PYRONES;

EID: 39549122207     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20071243     Document Type: Article

References (52)

1. Luster, A.D., R. Alon, and U.H. von Andrian, 2005, Immune cell migration in inflammation: present and future therapeutic targets. Nat. Immunol. 6:1182-1190.
2. Dawson, J., W. Miltz, A.K. Mir, and C. Wiessner, 2003, Targeting monocyte chemoattractant protein-1 signalling in disease. Expert Opin. Ther. Targets, 7:35-48.
3. Wyss-Coray, T., J.D. Loike, T.C. Brionne, E. Lu, R. Anankov, F. Yan, S.C. Silverstein, and J. Husemann, 2003, Adult mouse astrocytes degrade amyloid-beta in vitro and in situ. Nat. Med. 9:453-457.
4. Kurihara, T., G. Warr, J. Loy, and R. Bravo, 1997, Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J. Exp. Med. 186:1757-1762.
5. Gu, L., Y. Okada, S.K. Clinton, C. Gerard, G.K. Sukhova, P. Libby, and B.J. Rollins, 1998, Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol. Cell, 2:275-281.
6. Kuziel, W.A., S.J. Morgan, T.C. Dawson, S. Griffin, O. Smithies, K. Ley, and N. Maeda, 1997, Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc. Natl. Acad. Sci. USA, 94:12053-12058.
7. Lu, B., B.J. Rutledge, L. Gu, J. Fiorillo, N.W. Lukacs, S.L. Kunkel, R. North, C. Gerard, and B.J. Rollins, 1998, Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J. Exp. Med. 187:601-608.
8. Boring, L., J. Gosling, M. Cleary, and I.F. Charo, 1998, Decreased lesion formation in CCR2 - / - mice reveals a role for chemokines in the initiation of atherosclerosis. Nature, 394:894-897.
9. Kuang, Y., Y. Wu, H. Jiang, and D. Wu, 1996, Selective G protein coupling by C-C chemokine receptors. J. Biol. Chem. 271:3975-3978.
10. Cambien, B., M. Pomeranz, M.A. Millet, B. Rossi, and A. Schmid-Alliana, 2001, Signal transduction involved in MCP-1-mediated monocytic transendothelial migration. Blood, 97:359-366.
11. Jones, G.E., E. Prigmore, R. Calvez, C. Hogan, G.A. Dunn, E. Hirsch, M.P. Wymann, and A.J. Ridley, 2003, Requirement for PI 3-kinase gamma in macrophage migration to MCP-1 and CSF-1. Exp. Cell Res. 290:120-131.
12. Carnevale, K.A., and M.K. Cathcart, 2003, Protein kinase C beta is required for human monocyte chemotaxis to MCP-1. J. Biol. Chem. 278:25317-25322.
13. Mukai, Y., K. Iwaya, H. Ogawa, and K. Mukai, 2005, Involvement of Arp2/3 complex in MCP-1-induced chemotaxis. Biochem. Biophys. Res. Commun. 334:395-402.
14. Carnevale, K.A., and M.K. Cathcart, 2001, Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1. J. Immunol. 167:3414-3421.
15. Moran, J.M., R.M. Buller, J. McHowat, J. Turk, M. Wohltmann, R.W. Gross, and J.A. Corbett, 2005, Genetic and pharmacologic evidence that calcium-independent phospholipase A2beta regulates virus-induced inducible nitric-oxide synthase expression by macrophages. J. Biol. Chem. 280:28162-28168.
16. Ridley, A.J., and A. Hall, 1992, The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell, 70:389-399.
17. Wustner, D., M. Mondal, I. Tabas, and F.R. Maxfield, 2005, Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells. Traffic, 6:396-412.
18. Balsinde, J., M.A. Balboa, and E.A. Dennis, 1997, Antisense inhibition of group VI Ca2+-independent phospholipase A2 blocks phospholipid fatty acid remodeling in murine P388D1 macrophages. J. Biol. Chem. 272:29317-29321.
19. Balboa, M.A., and J. Balsinde, 2002, Involvement of calcium-independent phospholipase A2 in hydrogen peroxide-induced accumulation of free fatty acids in human U937 cells. J. Biol. Chem. 277:40384-40389.
20. Ramanadham, S., F.F. Hsu, S. Zhang, C. Jin, A. Bohrer, H. Song, S. Bao, Z. Ma, and J. Turk, 2004, Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta. Biochemistry, 43:918-930.
21. Bao, S., C. Jin, S. Zhang, J. Turk, Z. Ma, and S. Ramanadham, 2004, Beta-cell calcium-independent group VIA phospholipase A(2) (iPLA(2)beta): tracking iPLA(2)beta movements in response to stimulation with insulin secretagogues in INS-1 cells. Diabetes, 53:S186-S189.
22. Bolotina, V.M. 2004, Store-operated channels: diversity and activation mechanisms. Sci. STKE, 2004:pe34.
23. Sierra-Honigmann, M.R., J.R. Bradley, and J.S. Pober, 1996. "Cytosolic" phospholipase A2 is in the nucleus of subconfluent endothelial cells but confined to the cytoplasm of confluent endothelial cells and redistributes to the nuclear envelope and cell junctions upon histamine stimulation. Lab. Invest. 74:684-695.
24. Kan, H., Y. Ruan, and K.U. Malik, 1996, Involvement of mitogenactivated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells. Mol. Pharmacol. 50:1139-1147.
25. Herbert, S.P., S. Ponnambalam, and J.H. Walker, 2005, Cytosolic phospholipase A2-alpha mediates endothelial cell proliferation and is inactivated by association with the Golgi apparatus. Mol. Biol. Cell, 16:3800-3809.
26. Tou, J.S., and J.S. Gill, 2005, Lysophosphatidic acid increases phosphatidic acid formation, phospholipase D activity and degranulation by human neutrophils. Cell. Signal. 17:77-82.
27. Kam, Y., and J.H. Exton, 2001, Phospholipase D activity is required for actin stress fiber formation in fibroblasts. Mol. Cell. Biol. 21:4055-4066.
28. Tang, J., R.W. Kriz, N. Wolfman, M. Shaffer, J. Seehra, and S.S. Jones, 1997, A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs. J. Biol. Chem. 272:8567-8575.
29. Osterud, B., and E. Bjorklid, 2003, Role of monocytes in atherogenesis. Physiol. Rev. 83:1069-1112.
30. Maderna, P., D.C. Cottell, G. Berlasconi, N.A. Petasis, H.R. Brady, and C. Godson, 2002, Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: differential involvement of rho GTPases. Am. J. Pathol. 160:2275-2283.
31. van Helden, S.F., D.J. Krooshoop, K.C. Broers, R.A. Raymakers, C.G. Figdor, and F.N. van Leeuwen, 2006, A critical role for prostaglandin E2 in podosome dissolution and induction of high-speed migration during dendritic cell maturation. J. Immunol. 177:1567-1574.
32. Ridley, A.J., M.A. Schwartz, K. Burridge, R.A. Firtel, M.H. Ginsberg, G. Borisy, J.T. Parsons, and A.R. Horwitz, 2003, Cell migration: integrating signals from front to back. Science, 302:1704-1709.
33. Srinivasan, S., F. Wang, S. Glavas, A. Ott, F. Hofmann, K. Aktories, D. Kalman, and H.R. Bourne, 2003, Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. J. Cell Biol. 160:375-385.
34. Weiner, O.D., M.C. Rentel, A. Ott, G.E. Brown, M. Jedrychowski, M.B. Yaffe, S.P. Gygi, L.C. Cantley, H.R. Bourne, and M.W. Kirschner, 2006, Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis. PLoS Biol. 4:e38.
35. Kimura, K., M. Ito, M. Amano, K. Chihara, Y. Fukata, M. Nakafuku, B. Yamamori, J. Feng, T. Nakano, K. Okawa, et al, 1996, Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science, 273:245-248.
36. Pankov, R., Y. Endo, S. Even-Ram, M. Araki, K. Clark, E. Cukierman, K. Matsumoto, and K.M. Yamada, 2005, A Rac switch regulates random versus directionally persistent cell migration. J. Cell Biol. 170:793-802.
37. Wheeler, A.P., C.M. Wells, S.D. Smith, F.M. Vega, R.B. Henderson, V.L. Tybulewicz, and A.J. Ridley, 2006, Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. J. Cell Sci. 119:2749-2757.
38. Wells, C.M., P.J. Bhavsar, I.R. Evans, E. Vigorito, M. Turner, V. Tybulewicz, and A.J. Ridley, 2005, Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization. Exp. Cell Res. 310:303-310.
39. Francis, S.A., X. Shen, J.B. Young, P. Kaul, and D.J. Lerner, 2006, Rho GEF Lsc is required for normal polarization, migration, and adhesion of formyl-peptide-stimulated neutrophils. Blood, 107:1627-1635.
40. Hannigan, M., L. Zhan, Z. Li, Y. Ai, D. Wu, and C.K. Huang, 2002, Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. Proc. Natl. Acad. Sci. USA, 99:3603-3608.
41. Nishio, M., K. Watanabe, J. Sasaki, C. Taya, S. Takasuga, R. Iizuka, T. Balla, M. Yamazaki, H. Watanabe, R. Itoh, et al, 2007, Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat. Cell Biol. 9:36-44.
42. Franca-Koh, J., Y. Kamimura, and P.N. Devreotes, 2007, Leading-edge research: PtdIns(3,4,5)P3 and directed migration. Nat. Cell Biol. 9:15-17.
43. Ferguson, G.J., L. Milne, S. Kulkarni, T. Sasaki, S. Walker, S. Andrews, T. Crabbe, P. Finan, G. Jones, S. Jackson, et al, 2007, PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat. Cell Biol. 9:86-91.
44. Van Haastert, P.J., and D.M. Veltman, 2007, Chemotaxis: navigating by multiple signaling pathways. Sci. STKE, 2007:pe40.
45. Chen, L., M. Iijima, M. Tang, M.A. Landree, Y.E. Huang, Y. Xiong, P.A. Iglesias, and P.N. Devreotes, 2007, PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis. Dev. Cell, 12:603-614.
46. Brown, W.J., K. Chambers, and A. Doody, 2003, Phospholipase A2 (PLA2) enzymes in membrane trafficking: mediators of membrane shape and function. Traffic, 4:214-221.
47. Gomez-Mouton, C., R.A. Lacalle, E. Mira, S. Jimenez-Baranda, D.F. Barber, A.C. Carrera, A.C. Martinez, and S. Manes, 2004, Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis. J. Cell Biol. 164:759-768.
48. Bhattacharjee, A., R.S. Mishra, G. Feldman, and M.K. Cathcart, 2008, In vivo validation of signaling pathways regulating human monocyte chemotaxis. J. Immunol. Methods, In press.
49. McNally, A.K., G.M. Chisolm III, D.W. Morel, and M.K. Cathcart, 1990, Activated human monocytes oxidize low-density lipoprotein by a lipoxygenase-dependent pathway. J. Immunol. 145:254-259.
50. Heit, B., and P. Kubes, 2003, Measuring chemotaxis and chemokinesis: the under-agarose cell migration assay. Sci. STKE, 2003:PL5.
51. Low, S.H., A. Vasanji, J. Nanduri, M. He, N. Sharma, M. Koo, J. Drazba, and T. Weimbs, 2006, Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. Mol. Biol. Cell, 17:977-989.
52. Finkel, T., J.A. Theriot, K.R. Dise, G.F. Tomaselli, and P.J. Goldschmidt-Clermont, 1994, Dynamic actin structures stabilized by profilin. Proc. Natl. Acad. Sci. USA, 91:1510-1514.