Inhibition of secretory phospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model

Experimental Lung Research

Volumn 36, Issue 4, 2010, Pages 191-200

  Sato, Ryota ^a   Yamaga, Satoshi ^a   Watanabe, Kazuyoshi ^a   Hishiyama, Sensuke ^a   Kawabata, Ken Ichi ^a   Kobayashi, Tsuyoshi ^a   Fujioka, Daisuke ^a   Saito, Yukio ^a   Yano, Toshiaki ^a   Watanabe, Kazuhiro ^a   Watanabe, Yosuke ^a   Ishihara, Hiroshi ^a   Kugiyama, Kiyotaka ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Eicosanoids; Inhibitor; Lipopolysaccharide; Phospholipase A2

Indexed keywords

(3 AMINOOXALYL 1 BENZYL 2 ETHYL 6 METHYL 1H INDOL 4 YLOXY)ACETIC ACID METHYL ESTER; LEUKOTRIENE B4; LIPOPOLYSACCHARIDE; LY 329722; LY 374388; MESSENGER RNA; MYELOPEROXIDASE; PHOSPHOLIPASE A2; PHOSPHOLIPASE INHIBITOR; SODIUM (3 AMINOOXALYL 1 BENZYL 2 ETHYL 6 METHYL 1H INDOL 4 YLOXY)ACETIC ACID; THROMBOXANE B2; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC ANALYSIS; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACUTE LUNG INJURY; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DRUG EVALUATION, PRECLINICAL; INDOLEACETIC ACIDS; LEUKOTRIENE B4; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; PEROXIDASE; PHOSPHOLIPASES A2, SECRETORY; THROMBOXANE B2;

EID: 77951857388     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.3109/01902140903288026     Document Type: Article

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