Structure-activity relationship studies of 1-substituted 3-dodecanoylindole-2-carboxylic acids as inhibitors of cytosolic phospholipase A2-mediated arachidonic acid release in intact platelets

Archiv der Pharmazie

Volumn 335, Issue 11-12, 2002, Pages 547-555

  Griessbach, Klaus ^a   Klimt, Monika ^a   Elfringhoff, Alwine Schulze ^a   Lehr, Matthias ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

3 Dodecanoylindole 2 carboxylic acid; Cytosolic phospholipase A2; Structure activity relationship

Indexed keywords

1 [(6 CARBOXYNAPHTHALEN 2 YL)METHYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [2 (4 CARBOXYPHENYL)BENZYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [2 [4 (2 ACETYLAMINO 2 CARBOXYETHYL)PHENOXY]ETHYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [2 [4 (2 CARBOXYETHYL)PHENOXY]ETHYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [3 (4 CARBOXYPHENOXY)PROPYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [3 (4 CARBOXYPHENYL)BENZYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [3 (4 CARBOXYPHENYL)PROP 2 EN 1 YL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [4 (4 CARBOXYPHENOXY)BUTYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [4 (4 CARBOXYPHENYL)BENZYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [4 [4 (4 CARBOXYPHENYL)PHENYL]BENZYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [5 (4 CARBOXYPHENOXY)PENTYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 1 [8 (4 CARBOXYPHENOXY)OCTYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; 2 [4 [2 (2 CARBOXY 3 DODECANOYLINDOL 1 YL)ETHOXY]BENZYL]MALONIC ACID; ARACHIDONIC ACID; CALCIMYCIN; CARBOXYLIC ACID DERIVATIVE; DIETHYL 2 [4 (2 BROMOETHOXY)BENZYLIDENE]MALONATE; DIETHYL 2 [4 [2 (2 CARBOXY 3 DODECANOYLINDOL 1 YL)ETHOXY]BENZYLIDENE]MALONATE; ETHYL 1 [2 [4 (2 BENZYLOXYCARBONYLAMINO 2 ETHOXYCARBONYLETHYL)PHENOXY]ETHYL] 3 DODECANOYLINDOLE 2 CARBOXYLATE; ETHYL 1 [3 BROMO 3 (4 ETHOXYCARBONYLPHENYL)PROPYL] 3 DODECANOYLINDOLE 2 CARBOXYLATE; ETHYL 2 BENZYLOXYCARBONYLAMINO 3 [4 (2 BROMOETHOXY)PHENYL]PROPIONATE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THROMBOCYTE;

EID: 0036460991     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200290008     Document Type: Article

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