-
1
-
-
77953377258
-
IASP Council in Kyoto
-
Modified and improved for publication in Kyoto, Japan, 29-30 November
-
IASP Council in Kyoto. IASP Terminology. Modified and improved for publication in Kyoto, Japan, 29-30 November (2007).
-
(2007)
IASP Terminology
-
-
-
2
-
-
33947702144
-
Emerging drugs in neuropathic pain
-
Gilron I, Coderre TJ. Emerging drugs in neuropathic pain. Exp. Opin. Emerg. Drugs 12 (1), 113-126 (2007).
-
(2007)
Exp. Opin. Emerg. Drugs
, vol.12
, Issue.1
, pp. 113-126
-
-
Gilron, I.1
Coderre, T.J.2
-
3
-
-
32244442392
-
Mechanisms of disease: Neuropathic pain - A clinical perspective
-
Baron R. Mechanisms of disease: neuropathic pain - a clinical perspective. Nat. Clin. Pract. 2 (2), 95-106 (2006).
-
(2006)
Nat. Clin. Pract.
, vol.2
, Issue.2
, pp. 95-106
-
-
Baron, R.1
-
4
-
-
0142157604
-
Complex regional pain syndrome: Mystery explained?
-
Janig W, Baron R. Complex regional pain syndrome: mystery explained? Lancet Neurol. 2, 687-697 (2003).
-
(2003)
Lancet Neurol.
, vol.2
, pp. 687-697
-
-
Janig, W.1
Baron, R.2
-
6
-
-
0141458065
-
The role of N-methyl-D-aspartate (NMDA) receptors in pain: A review
-
Petrenko AB, Yamakura T, Baba H, Shimoji K. The role of N-methyl-D-aspartate (NMDA) receptors in pain: a review. Anesth. Analg. 97 (4), 1108-1116 (2003).
-
(2003)
Anesth. Analg.
, vol.97
, Issue.4
, pp. 1108-1116
-
-
Petrenko, A.B.1
Yamakura, T.2
Baba, H.3
Shimoji, K.4
-
7
-
-
58149503772
-
Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain
-
Qu XX, Cai J, Li MJ et al. Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain. Exp. Neurol. 215 (2), 298-307 (2009).
-
(2009)
Exp. Neurol.
, vol.215
, Issue.2
, pp. 298-307
-
-
Qu, X.X.1
Cai, J.2
Li, M.J.3
-
8
-
-
26244444488
-
Central proinflammatory cytokines and pain enhancement
-
Wieseler-Frank J, Maier SF, Watkins LR. Central proinflammatory cytokines and pain enhancement. Neurosignals 14, 166-174 (2005).
-
(2005)
Neurosignals
, vol.14
, pp. 166-174
-
-
Wieseler-Frank, J.1
Maier, S.F.2
Watkins, L.R.3
-
9
-
-
57749200564
-
Pathological and protective roles of glia in chronic pain
-
Milligan ED, Watkins LR. Pathological and protective roles of glia in chronic pain. Nat. Rev. Neurosci. 10, 23-36 (2009).
-
(2009)
Nat. Rev. Neurosci.
, vol.10
, pp. 23-36
-
-
Milligan, E.D.1
Watkins, L.R.2
-
10
-
-
30844471383
-
Ion channel targets and treatment efficacy in neuropathic pain
-
Markman JD, Dworkin RH. Ion channel targets and treatment efficacy in neuropathic pain. J. Pain 7 (1S), S38-S47 (2006).
-
(2006)
J. Pain
, vol.7
, Issue.1
-
-
Markman, J.D.1
Dworkin, R.H.2
-
11
-
-
66449112479
-
Voltage-gated sodium channel blockers for the treatment of chronic pain
-
Matulenko MA, Scanio M J C, Kort, ME. Voltage-gated sodium channel blockers for the treatment of chronic pain. Curr. Top. Med. Chem. 9, 362-376 (2009).
-
(2009)
Curr. Top. Med. Chem.
, vol.9
, pp. 362-376
-
-
Matulenko, M.A.1
Scanio, M.J.C.2
Kort, M.E.3
-
12
-
-
67650590969
-
Purinergic receptors and pain
-
Burnstock G. Purinergic receptors and pain. Curr. Pharm. Des. 15 (15), 1717-1735 (2009).
-
(2009)
Curr. Pharm. Des.
, vol.15
, Issue.15
, pp. 1717-1735
-
-
Burnstock, G.1
-
13
-
-
67650635085
-
TRP channels and pain
-
Very useful and informative review on the role of transient receptor potential channels in pain transduction
-
Cortright DN, Szallasi A. TRP channels and pain. Curr. Pharm. Des. 15 (15), Very useful and informative review on the role of transient receptor potential channels in pain transduction.
-
Curr. Pharm. Des.
, vol.15
, Issue.15
-
-
Cortright, D.N.1
Szallasi, A.2
-
14
-
-
67650627679
-
Acid sensing ion channels and acid nociception
-
Dubé GR, Elagoz A, Mangat H. Acid sensing ion channels and acid nociception. Curr. Pharm. Des. 15 (15), 1750-1766 (2009).
-
(2009)
Curr. Pharm. Des.
, vol.15
, Issue.15
, pp. 1750-1766
-
-
Dubé, G.R.1
Elagoz, A.2
Mangat, H.3
-
15
-
-
67650608109
-
Hyperpolarization-activated cyclic nucleotidegated (HCN) channels and pain
-
Dunlop J, Vasilyev D, Lu P et al. Hyperpolarization-activated cyclic nucleotidegated (HCN) channels and pain. Curr. Pharm. Des. 15 (15), 1767-1772 (2009).
-
(2009)
Curr. Pharm. Des.
, vol.15
, Issue.15
, pp. 1767-1772
-
-
Dunlop, J.1
Vasilyev, D.2
Lu, P.3
-
17
-
-
45849128645
-
Neuropathic pain: Emerging treatments
-
Useful reference for a broad overview of current and future neuropathic pain treatments
-
Dray A. Neuropathic pain: emerging treatments. Br. J. Anaesth. 101 (1), 48-58 (2008). Useful reference for a broad overview of current and future neuropathic pain treatments.
-
(2008)
Br. J. Anaesth.
, vol.101
, Issue.1
, pp. 48-58
-
-
Dray, A.1
-
18
-
-
63449107353
-
Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment
-
+ channels subtypes as pain targets and the influence of their biophysical properties on pain conditions
-
+ channels subtypes as pain targets and the influence of their biophysical properties on pain conditions.
-
(2009)
Brain Res. Rev.
, vol.60
, Issue.1
, pp. 65-83
-
-
Dib-Hajj, S.D.1
Binshtok, A.M.2
Cummins, T.R.3
-
19
-
-
29844438166
-
International union of pharmacology. XLVII. Nomenclature and structurefunction relationships of voltage-gated sodium channels
-
Key reference providing an overview of the general properties, physiological role and pharmacological significance of the voltage gated sodium channel
-
Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII. Nomenclature and structurefunction relationships of voltage-gated sodium channels. Pharmacol. Rev. 57, 397-409 (2005). Key reference providing an overview of the general properties, physiological role and pharmacological significance of the voltage gated sodium channel.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 397-409
-
-
Catterall, W.A.1
Goldin, A.L.2
Waxman, S.G.3
-
21
-
-
34548476521
-
The roles of sodium channels in nociception: Implications for mechanisms of pain
-
Cummins TR, Sheets PL, Waxman SG. The roles of sodium channels in nociception: implications for mechanisms of pain. Pain 131 (3), 243-257 (2007).
-
(2007)
Pain
, vol.131
, Issue.3
, pp. 243-257
-
-
Cummins, T.R.1
Sheets, P.L.2
Waxman, S.G.3
-
22
-
-
70149097762
-
Future potential and status of selective sodium channel blockers for the treatment of pain
-
Priest BT. Future potential and status of selective sodium channel blockers for the treatment of pain. Curr. Opin. Drug Discov. & Develop. 12 (5), 682-692 (2009).
-
(2009)
Curr. Opin. Drug Discov. & Develop
, vol.12
, Issue.5
, pp. 682-692
-
-
Priest, B.T.1
-
23
-
-
0027933696
-
Type III sodium channel mRNA is expressed in embryonic but not in adult spinal sensory neurons, and is re-expressed following axotomy
-
Waxman SG, Kocsis JD, Black JA. Type III sodium channel mRNA is expressed in embryonic but not in adult spinal sensory neurons, and is re-expressed following axotomy. J. Neurophysiol. 72, 466-470 (1994).
-
(1994)
J. Neurophysiol.
, vol.72
, pp. 466-470
-
-
Waxman, S.G.1
Kocsis, J.D.2
Black, J.A.3
-
24
-
-
0141529982
-
v1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury
-
v1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury. J. Neurosci. 23, 8881-8892 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 8881-8892
-
-
Hains, B.C.1
Klein, J.P.2
Saab, C.Y.3
-
25
-
-
2442651551
-
Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury
-
Hains BC, Saab CY, Klein JP et al. Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury. J. Neurosci. 24, 4832-4839 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 4832-4839
-
-
Hains, B.C.1
Saab, C.Y.2
Klein, J.P.3
-
26
-
-
0035809748
-
Plasticity of TTX-sensitive sodium channels PNI and brain III in injured human nerves
-
Coward K, Aitken A, Powell C et al. Plasticity of TTX-sensitive sodium channels PNI and brain III in injured human nerves. Neuroreport 12, 495-500 (2001).
-
(2001)
Neuroreport
, vol.12
, pp. 495-500
-
-
Coward, K.1
Aitken, A.2
Powell, C.3
-
27
-
-
58149232445
-
Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas
-
Black JA, Nikolajsen L, Kroner K et al. Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas. Ann. Neurol. 64 (6), 644-653 (2008).
-
(2008)
Ann. Neurol.
, vol.64
, Issue.6
, pp. 644-653
-
-
Black, J.A.1
Nikolajsen, L.2
Kroner, K.3
-
28
-
-
0030997916
-
Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury
-
Cummins TR, Waxman SG. Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury. J. Neurosci. 17, 3503-3514 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 3503-3514
-
-
Cummins, T.R.1
Waxman, S.G.2
-
29
-
-
0035882277
-
vv1.3 sodium channels: Rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons
-
vv1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. J. Neurosci. 21, 5952-5961 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 5952-5961
-
-
Cummins, T.R.1
Aglieco, F.2
Renganathan, M.3
-
30
-
-
33749326179
-
Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury
-
Lampert A, Hains BC, Waxman SG. Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury. Exp. Brain Res. 174, 660-666 (2006).
-
(2006)
Exp. Brain Res.
, vol.174
, pp. 660-666
-
-
Lampert, A.1
Hains, B.C.2
Waxman, S.G.3
-
31
-
-
28844448678
-
v1.3 expression and neuropathic pain behavior in rats
-
v1.3 expression and neuropathic pain behavior in rats. Pain 117, 145-153 (2005).
-
(2005)
Pain
, vol.117
, pp. 145-153
-
-
Lindia, J.A.1
Kohler, M.G.2
Martin, W.J.3
-
33
-
-
23444443202
-
v1.7 in familial erythromelalgia induces bursting of sensory neurons
-
v1.7 in familial erythromelalgia induces bursting of sensory neurons. Brain 128 (8), 1847-1854 (2005).
-
(2005)
Brain
, vol.128
, Issue.8
, pp. 1847-1854
-
-
Dib-Hajj, S.D.1
Rush, A.M.2
Cummins, T.R.3
-
36
-
-
36849036949
-
Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders
-
Drenth JP, Waxman SG. Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders. J. Clin. Invest. 117 (12), 3603-3609 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.12
, pp. 3603-3609
-
-
Drenth, J.P.1
Waxman, S.G.2
-
37
-
-
33847168937
-
SCN9A mutations in paroxysmal extreme pain disorder: Allelic variants underlie distinct channel defects and phenotypes
-
Fertleman CR, Baker MD, Parker KA et al. SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron 52, 767-774 (2006).
-
(2006)
Neuron
, vol.52
, pp. 767-774
-
-
Fertleman, C.R.1
Baker, M.D.2
Parker, K.A.3
-
38
-
-
33845901486
-
An SCN9A channelopathy causes congenital inability to experience pain
-
v1.7 gene determine congenital insensitivity to pain
-
v1.7 gene determine congenital insensitivity to pain.
-
(2006)
Nature
, vol.444
, pp. 894-898
-
-
Cox, J.J.1
Reimann, F.2
Nicholas, A.K.3
-
39
-
-
34247874778
-
v1.7 gene underlie congenital indifference to pain in multiple human populations
-
v1.7 channel and congenital indifference to pain and provides a thorough clinical description of the congenital indifference to pain phenotype
-
v1.7 channel and congenital indifference to pain and provides a thorough clinical description of the congenital indifference to pain phenotype.
-
(2007)
Clin. Genet.
, vol.71
, pp. 311-319
-
-
Goldberg, Y.1
Macfarlane, J.2
Macdonald, M.3
-
42
-
-
33845271929
-
v1.7 mutant A863P in erythromelalgia: Effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons
-
v1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons. J. Neurosci. 26, 12566-12575 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 12566-12575
-
-
Harty, T.P.1
Dib-Hajj, S.D.2
Tyrrell, L.3
-
43
-
-
33744454923
-
A single sodium channel mutation produces hyperor hypoexcitability in different types of neurons
-
Rush AM, Dib-Hajj SD, Liu S et al. A single sodium channel mutation produces hyperor hypoexcitability in different types of neurons. Proc. Natl. Acad. Sci. USA 103, 8245-8250 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8245-8250
-
-
Rush, A.M.1
Dib-Hajj, S.D.2
Liu, S.3
-
44
-
-
33846974357
-
Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons
-
Illustrates how excitability can be finely tuned by complementary expression of different sodium channel types to provide contrasting firing templates in different subclasses of dorsal root ganglion neurons
-
Rush AM, Cummins TR, Waxman SG. Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons. J. Physiol. (London) 579 (1), 1-14 (2007). Illustrates how excitability can be finely tuned by complementary expression of different sodium channel types to provide contrasting firing templates in different subclasses of dorsal root ganglion neurons.
-
(2007)
J. Physiol. (London)
, vol.579
, Issue.1
, pp. 1-14
-
-
Rush, A.M.1
Cummins, T.R.2
Waxman, S.G.3
-
45
-
-
0027414377
-
Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia
-
Elliott AA, Elliott JR. Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia. J. Physiol. 463, 39-56 (1993).
-
(1993)
J. Physiol.
, vol.463
, pp. 39-56
-
-
Elliott, A.A.1
Elliott, J.R.2
-
46
-
-
0033363999
-
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
-
Akopian AN, Souslova V, England S et al. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat. Neurosci. 2, 541-548 (1999).
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 541-548
-
-
Akopian, A.N.1
Souslova, V.2
England, S.3
-
48
-
-
1542498432
-
Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain
-
Black JA, Liu S, Tanaka M et al. Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain. Pain 108, 237-247 (2004).
-
(2004)
Pain
, vol.108
, pp. 237-247
-
-
Black, J.A.1
Liu, S.2
Tanaka, M.3
-
51
-
-
0029907091
-
Downregulation of transcripts for Na channel a-SNS in spinal sensory neurons following axotomy
-
Dib-Hajj S, Black JA, Felts P et al. Downregulation of transcripts for Na channel a-SNS in spinal sensory neurons following axotomy. Proc. Natl. Acad. Sci. USA 93, 14950-14954 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14950-14954
-
-
Dib-Hajj, S.1
Black, J.A.2
Felts, P.3
-
52
-
-
0030997916
-
Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury
-
Cummins TR, Waxman SG. Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury. J. Neurosci. 17, 3503-3514 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 3503-3514
-
-
Cummins, T.R.1
Waxman, S.G.2
-
53
-
-
0032723079
-
Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain
-
Dib-Hajj SD, Fjell J, Cummins TR et al. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain 83, 591-600 (1999).
-
(1999)
Pain
, vol.83
, pp. 591-600
-
-
Dib-Hajj, S.D.1
Fjell, J.2
Cummins, T.R.3
-
54
-
-
0032521091
-
Distribution of the tetrodotoxinresistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions
-
Novakovic SD, Tzoumaka E, McGivern JG et al. Distribution of the tetrodotoxinresistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions. J. Neurosci. 15, 18 (6) 2174-2187 (1998).
-
(1998)
J. Neurosci.
, vol.15-18
, Issue.6
, pp. 2174-2187
-
-
Novakovic, S.D.1
Tzoumaka, E.2
McGivern, J.G.3
-
56
-
-
0033572137
-
A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons
-
Cummins TR, Dib-Hajj SD, Black JA et al. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. J. Neurosci. 19, RC43 (1999).
-
(1999)
J. Neurosci.
, vol.19
-
-
Cummins, T.R.1
Dib-Hajj, S.D.2
Black, J.A.3
-
57
-
-
0041974814
-
v1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice
-
v1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice. J. Physiol. 550, 921-926 (2003).
-
(2003)
J. Physiol.
, vol.550
, pp. 921-926
-
-
Roza, C.1
Laird, J.M.A.2
Souslova, V.3
-
58
-
-
0001059602
-
A comparison of the potential role of the tetrodotoxininsensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain
-
Porreca F, Lai J, Bian D et al. A comparison of the potential role of the tetrodotoxininsensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain. Proc. Natl Acad. Sci. USA 96, 7640-7644 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7640-7644
-
-
Porreca, F.1
Lai, J.2
Bian, D.3
-
60
-
-
33845631301
-
v1.9 is an effector of peripheral inflammatory pain hypersensitivity
-
v1.9 is an effector of peripheral inflammatory pain hypersensitivity. J. Neurosci. 26, 12852-12860 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 12852-12860
-
-
Amaya, F.1
Wang, H.2
Costigan, M.3
-
61
-
-
34249950792
-
Antiepileptic drugs in the treatment of neuropathic pain
-
Eisenberg E, River Y, Shifrin A et al. Antiepileptic drugs in the treatment of neuropathic pain. Drugs 67 (9), 1265-1289 (2007).
-
(2007)
Drugs
, vol.67
, Issue.9
, pp. 1265-1289
-
-
Eisenberg, E.1
River, Y.2
Shifrin, A.3
-
62
-
-
0032729936
-
Efficacy of pharmacological treatments of neuropathic pain: An update and effect related to mechanism of drug action
-
Sindrup HJ, Jensen TS. Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action. Pain 83, 389-400 (1999).
-
(1999)
Pain
, vol.83
, pp. 389-400
-
-
Sindrup, H.J.1
Jensen, T.S.2
-
64
-
-
0036158768
-
Pharmacotherapy of trigeminal neuralgia
-
Sindrup, SH, Jensen TS. Pharmacotherapy of trigeminal neuralgia. Clin. J. Pain 18, 22-27 (2002).
-
(2002)
Clin. J. Pain
, vol.18
, pp. 22-27
-
-
Sindrup, S.H.1
Jensen, T.S.2
-
65
-
-
0016170761
-
Tegretol in the treatment of diabetic neuropathy
-
Wilton TD. Tegretol in the treatment of diabetic neuropathy. S. Afr. Med. J. 48 (20), 869-872 (1974).
-
(1974)
S. Afr. Med. J.
, vol.48
, Issue.20
, pp. 869-872
-
-
Wilton, T.D.1
-
66
-
-
0029796752
-
Nortriptyline-fluphenazine vs carbamazepine in the symptomatic treatment of diabetic neuropathy
-
Gomez-Perez FJ, Choza R, Rios JM et al. Nortriptyline-fluphenazine vs carbamazepine in the symptomatic treatment of diabetic neuropathy. Arch. Med. Res. 27, 525-529 (1996).
-
(1996)
Arch. Med. Res.
, vol.27
, pp. 525-529
-
-
Gomez-Perez, F.J.1
Choza, R.2
Rios, J.M.3
-
67
-
-
33846822016
-
Are sodium channel blockers useless in peripheral neuropathic pain?
-
Sindrup SJ, Jensen TS. Are sodium channel blockers useless in peripheral neuropathic pain? aPain 128, 6-7 (2007).
-
(2007)
APain
, vol.128
, pp. 6-7
-
-
Sindrup, S.J.1
Jensen, T.S.2
-
68
-
-
70349335964
-
Sodium channel blockers for the treatment of neuropathic pain
-
Bhattacharya A, Wickenden AD, Chaplan SR. Sodium channel blockers for the treatment of neuropathic pain. Neurother. 6 (4), 663-678 (2009).
-
(2009)
Neurother.
, vol.6
, Issue.4
, pp. 663-678
-
-
Bhattacharya, A.1
Wickenden, A.D.2
Chaplan, S.R.3
-
69
-
-
36148978879
-
Voltage-gated sodium channel blockers for the treatment of neuropathic pain
-
Cummins TR, Rush AM. Voltage-gated sodium channel blockers for the treatment of neuropathic pain. Exp. Rev. Neurother. 7 (11), 1597-1612 (2007).
-
(2007)
Exp. Rev. Neurother.
, vol.7
, Issue.11
, pp. 1597-1612
-
-
Cummins, T.R.1
Rush, A.M.2
-
70
-
-
33847148953
-
Blocking sodium channels to treat neuropathic pain
-
Priest BT, Kaczorowski GJ. Blocking sodium channels to treat neuropathic pain. Expert Opin. Ther. Targets 11 (3), 291-306 (2007).
-
(2007)
Expert Opin. Ther. Targets
, vol.11
, Issue.3
, pp. 291-306
-
-
Priest, B.T.1
Kaczorowski, G.J.2
-
71
-
-
55849117323
-
Current challenges and future prospects in management of neuropathic pain
-
Jain KK. Current challenges and future prospects in management of neuropathic pain. Expert Rev. Neurother. 8 (11), 1743-1756 (2008).
-
(2008)
Expert Rev. Neurother.
, vol.8
, Issue.11
, pp. 1743-1756
-
-
Jain, K.K.1
-
72
-
-
67649948710
-
Small molecules targeting sodium and calcium channels for neuropathic pain
-
Updated and thorough review of the new trends in the medicinal chemistry of sodium and calcium channel blockers
-
Bear B, Asgian J, Termin A, Zimmermann N. Small molecules targeting sodium and calcium channels for neuropathic pain. Curr. Opin. Drug Discov. Develop. 12 (4), 543-561 (2009). Updated and thorough review of the new trends in the medicinal chemistry of sodium and calcium channel blockers.
-
(2009)
Curr. Opin. Drug Discov. Develop
, vol.12
, Issue.4
, pp. 543-561
-
-
Bear, B.1
Asgian, J.2
Termin, A.3
Zimmermann, N.4
-
73
-
-
34948819283
-
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers
-
Binshtok AM, Bean BP, Woolf CJ. Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature 447, 607-611 (2007).
-
(2007)
Nature
, vol.447
, pp. 607-611
-
-
Binshtok, A.M.1
Bean, B.P.2
Woolf, C.J.3
-
74
-
-
77953468230
-
v1.8 alleviates experimentally-induced chronic pain
-
th, Atlanta, GA, USA, 14-18 October, Abstract 245.11
-
th Annual Meeting of the Society for Neuroscience. Atlanta, GA, USA, 14-18 October 2006 (Abstract 245.11).
-
(2006)
Annual Meeting of the Society for Neuroscience
-
-
Sah, D.1
Guo, W.2
Luo, M.3
-
75
-
-
29844439240
-
International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltagegated calcium channels
-
Key reference overview of the general properties, physiological role and pharmacological significance of the voltage-gated cation channel
-
Catterall WA, Perez-Reyes E, Snutch T P, Striessnig J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltagegated calcium channels. Pharmacol. Rev. 57 (4), 411-425 (2005). Key reference overview of the general properties, physiological role and pharmacological significance of the voltage-gated cation channel.
-
(2005)
Pharmacol. Rev.
, vol.57
, Issue.4
, pp. 411-425
-
-
Catterall, W.A.1
Perez-Reyes, E.2
Snutch, T.P.3
Striessnig, J.4
-
76
-
-
0036450543
-
2+ channels in the rat spinal cord following chronic constrictive nerve injury
-
2+ channels in the rat spinal cord following chronic constrictive nerve injury. Exp. Brain Res. 147, 456-463 (2002).
-
(2002)
Exp. Brain Res.
, vol.147
, pp. 456-463
-
-
Cizkova, D.1
Marsala, J.2
Lukacova, N.3
-
77
-
-
0035869568
-
Upregulation of dorsal root ganglion (α) 2 (δ) calcium channel subunit and its correlation with allodynia in spinal nerve injured rats
-
Luo ZD, Chaplan SR, HigueraES et al. Upregulation of dorsal root ganglion (α) 2 (δ) calcium channel subunit and its correlation with allodynia in spinal nerve injured rats. J. Neurosci. 21 (6), 1868-1875 (2001).
-
(2001)
J. Neurosci.
, vol.21
, Issue.6
, pp. 1868-1875
-
-
Luo, Z.D.1
Chaplan, S.R.2
Higuera, E.S.3
-
78
-
-
55749094173
-
2+ channels with gene knockout models
-
2+ channels with gene knockout models. Channels 2 (4), 1-19 (2008).
-
(2008)
Channels
, vol.2
, Issue.4
, pp. 1-19
-
-
Striessnig, J.1
Koschak, A.2
-
79
-
-
17944371076
-
Altered nociceptive response in mice deficient in the α (1B) subunit of the voltage-dependent calcium channel
-
Kim C, Jun. K, Lee T et al. Altered nociceptive response in mice deficient in the α (1B) subunit of the voltage-dependent calcium channel. Mol. Cell. Neurosci. 18, 235-245 (2001).
-
(2001)
Mol. Cell. Neurosci.
, vol.18
, pp. 235-245
-
-
Kim, C.1
Jun, K.2
Lee, T.3
-
81
-
-
46749141315
-
Ziconotide: An update and review
-
Recent review reporting information about pharmacokinetic properties, safety aspects and clinical efficacy of ziconotide
-
Williams JA, Day M, Heavner JE. Ziconotide: an update and review. Expert Opin. Pharmacother. 9 (9), 1575-1583 (2008). Recent review reporting information about pharmacokinetic properties, safety aspects and clinical efficacy of ziconotide.
-
(2008)
Expert Opin. Pharmacother.
, vol.9
, Issue.9
, pp. 1575-1583
-
-
Williams, J.A.1
Day, M.2
Heavner, J.E.3
-
82
-
-
59849100357
-
Intrathecal therapy with ziconotide: Clinical experience and consideration on its use
-
Vitale V, Battelli D, Gasperoni E, Monachese N. Intrathecal therapy with ziconotide: clinical experience and consideration on its use. Minerva Anestesiol. 74, 727-733 (2008).
-
(2008)
Minerva Anestesiol
, vol.74
, pp. 727-733
-
-
Vitale, V.1
Battelli, D.2
Gasperoni, E.3
Monachese, N.4
-
83
-
-
70049091197
-
Pregabalin for acute and chronic pain in adults
-
Database collection of available information from clinical trials to assess analgesic efficacy and associated adverse events of pregabalin in acute and chronic pain
-
Moore RA, Straube S, Wiffen PJ, Derry S, McQuay HJ. Pregabalin for acute and chronic pain in adults. Cochrane Database Syst. Rev. 8 (3), CD007076 (2009). Database collection of available information from clinical trials to assess analgesic efficacy and associated adverse events of pregabalin in acute and chronic pain.
-
(2009)
Cochrane Database Syst. Rev.
, vol.8
, Issue.3
-
-
Moore, R.A.1
Straube, S.2
Wiffen, P.J.3
Derry, S.4
McQuay, H.J.5
-
84
-
-
36549018640
-
Pregabalin: Its pharmacology and use in pain management
-
Noor M, Gajraj NM. Pregabalin: its pharmacology and use in pain management Anesth. Analg. 105 (6), 1805-1815 (2007).
-
(2007)
Anesth. Analg.
, vol.105
, Issue.6
, pp. 1805-1815
-
-
Noor, M.1
Gajraj, N.M.2
-
85
-
-
70349308546
-
Pregabalin: In the treatment of postherpetic neuralgia
-
McKeage K, Keam SJ. Pregabalin: in the treatment of postherpetic neuralgia. Drugs Aging 26 (10), 883-892 (2009).
-
(2009)
Drugs Aging
, vol.26
, Issue.10
, pp. 883-892
-
-
McKeage, K.1
Keam, S.J.2
-
86
-
-
60049094857
-
vα2-δ] ligands
-
vα2-δ] ligands. Pain 142 (1-2), 13-16 (2009).
-
(2009)
Pain
, vol.142
, Issue.1-2
, pp. 13-16
-
-
Taylor, C.P.1
-
87
-
-
34247472063
-
2-δ subunits of voltage-gated calcium channels
-
2-δ subunits of voltage-gated calcium channels. aTrends Pharmacol. Sci. 28 (5), 220-228 (2007).
-
(2007)
ATrends Pharmacol. Sci.
, vol.28
, Issue.5
, pp. 220-228
-
-
Davies, A.1
Hendrich, J.2
Van Minh, T.A.3
Wratten, J.4
Douglas, L.5
Dolphin, A.C.6
-
88
-
-
55749094363
-
Time course and specificity of the pharmacological disruption of the trafficking of voltage-gated calcium channels by gabapentin
-
Heblich F, Tran Van Minh A, Hendrich J, Watschinger K, Dolphin AC. Time course and specificity of the pharmacological disruption of the trafficking of voltage-gated calcium channels by gabapentin. Channels 2 (1), 4-9 (2008).
-
(2008)
Channels
, vol.2
, Issue.1
, pp. 4-9
-
-
Heblich, F.1
Van Minh, T.A.2
Hendrich, J.3
Watschinger, K.4
Dolphin, A.C.5
-
89
-
-
0037207469
-
Molecular physiology of low-voltage-activated T-type calcium channels
-
Perez-Reyes E. Molecular physiology of low-voltage-activated T-type calcium channels. Physiol. Rev. 83, 117-161, (2003).
-
(2003)
Physiol. Rev.
, vol.83
, pp. 117-161
-
-
Perez-Reyes, E.1
-
90
-
-
57049150228
-
Upregulation of the T-type calcium current in small rat sensory neurons after chronic constrictive injury of the sciatic nerve
-
Jagodic MM, Pathirathna S, Joksovic PM et al. Upregulation of the T-type calcium current in small rat sensory neurons after chronic constrictive injury of the sciatic nerve. J. Neurophysiol. 99, 3151-3156 (2008).
-
(2008)
J. Neurophysiol.
, vol.99
, pp. 3151-3156
-
-
Jagodic, M.M.1
Pathirathna, S.2
Joksovic, P.M.3
-
91
-
-
33947503158
-
Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons
-
Jagodic MM, Pathirathna S, Nelson MT et al. Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons. J. Neurosci. 27 (12), 3305-3316 (2007).
-
(2007)
J. Neurosci.
, vol.27
, Issue.12
, pp. 3305-3316
-
-
Jagodic, M.M.1
Pathirathna, S.2
Nelson, M.T.3
-
92
-
-
53049107799
-
Regulation of T-type channels in the peripheral pain pathway
-
Todorovic SM, Jevtovic-Todorovic V. Regulation of T-type channels in the peripheral pain pathway. Channels 4, 238-245 (2007).
-
(2007)
Channels
, vol.4
, pp. 238-245
-
-
Todorovic, S.M.1
Jevtovic-Todorovic, V.2
-
93
-
-
0037217589
-
Loss of T-type calcium current in sensory neurons of rats with neuropathic pain
-
McCallum JB, Kwok WM, Mynlieff M, Bosnjak ZJ, Hogan QH. Loss of T-type calcium current in sensory neurons of rats with neuropathic pain. Anesthesiology 98, 209-216 (2003).
-
(2003)
Anesthesiology
, vol.98
, pp. 209-216
-
-
McCallum, J.B.1
Kwok, W.M.2
Mynlieff, M.3
Bosnjak, Z.J.4
Hogan, Q.H.5
-
94
-
-
0036582755
-
Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons
-
Wolfart J, Roeper J. Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons. J. Neurosci. 22, 3404-3413 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 3404-3413
-
-
Wolfart, J.1
Roeper, J.2
-
96
-
-
20144385871
-
v3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception
-
v3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception. EMBO J. 24, 315-324 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 315-324
-
-
Bourinet, E.1
Alloui, A.2
Monteiol, A.3
-
97
-
-
46749119085
-
Linking calcium channel isoforms to potential therapies
-
Comprehensive overview of progress in the development of calcium channel therapeutics in the pain therapeutic area
-
Belardetti F, Zamponi GW. Linking calcium channel isoforms to potential therapies Curr. Opin. Invest. Drugs 7, 707-715 (2008). Comprehensive overview of progress in the development of calcium channel therapeutics in the pain therapeutic area.
-
(2008)
Curr. Opin. Invest. Drugs
, vol.7
, pp. 707-715
-
-
Belardetti, F.1
Zamponi, G.W.2
-
98
-
-
36549018640
-
Pregabalin: Its pharmacology and use in pain management
-
Gajraj NM. Pregabalin: its pharmacology and use in pain management. Anesth. Analg. 6, 1805-1815 (2007).
-
(2007)
Anesth. Analg.
, vol.6
, pp. 1805-1815
-
-
Gajraj, N.M.1
-
99
-
-
75249106626
-
CNSB004 (Leconotide) causes antihyperalgesia without side effects when given intravenously: A comparison with ziconotide in a rat model of diabetic neuropathic pain
-
Kolosov A, Goodchild CS, Cook I et al. CNSB004 (Leconotide) causes antihyperalgesia without side effects when given intravenously: a comparison with ziconotide in a rat model of diabetic neuropathic pain. Pain Med. 11, 262-273 (2010).
-
(2010)
Pain Med.
, vol.11
, pp. 262-273
-
-
Kolosov, A.1
Goodchild, C.S.2
Cook, I.3
-
100
-
-
66449104102
-
Recent updates of N-type calcium channel blockers with therapeutic potential for neuropathic pain and stroke
-
Yamamoto T, Takahara A. Recent updates of N-type calcium channel blockers with therapeutic potential for neuropathic pain and stroke. Curr. Top. Med. Chem. 9, 377-395 (2009).
-
(2009)
Curr. Top. Med. Chem.
, vol.9
, pp. 377-395
-
-
Yamamoto, T.1
Takahara, A.2
-
101
-
-
29844437655
-
International union of pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
-
Gutman GA, Chandy KG, Grissmer S et al. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol. Rev. 57, 473-508 (2005).
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 473-508
-
-
Gutman, G.A.1
Chandy, K.G.2
Grissmer, S.3
-
102
-
-
29844439979
-
International union of pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels
-
Wei AD, Gutman GA, Aldrich R et al. International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels. Pharmacol. Rev. 57, 463-472 (2005).
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 463-472
-
-
Wei, A.D.1
Gutman, G.A.2
Aldrich, R.3
-
103
-
-
29844450489
-
International union of pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels
-
Kubo Y, Adelman JP, Clapham DE et al. International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol. Rev. 57, 509-526 (2005).
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 509-526
-
-
Kubo, Y.1
Adelman, J.P.2
Clapham, D.E.3
-
104
-
-
29844435013
-
International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels
-
Goldstein S A N, Bayliss DA, Kim D et al. International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacol. Rev. 57, 527-540 (2005).
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 527-540
-
-
Goldstein, S.A.N.1
Bayliss, D.A.2
Kim, D.3
-
105
-
-
4644237028
-
Potassium channels and pain: Present realities and future opportunities
-
Ocana M, Cendan CM, Cobos EJ, Entrena JM, Baeyens, JM. Potassium channels and pain: present realities and future opportunities. Eur. J. Pharmacol. 500, 203-219 (2004).
-
(2004)
Eur. J. Pharmacol.
, vol.500
, pp. 203-219
-
-
Ocana, M.1
Cendan, C.M.2
Cobos, E.J.3
Entrena, J.M.4
Baeyens, J.M.5
-
106
-
-
34548641073
-
Reduced expression of A-type potassium channels in primary sensory neurons induces mechanical hypersensitivity
-
Chien L-Y, Cheng J-K, Chu D, Cheng C-F, Tsaur M-L. Reduced expression of A-type potassium channels in primary sensory neurons induces mechanical hypersensitivity. J. Neurosci. 27 (37), 9855-9865 (2007).
-
(2007)
J. Neurosci.
, vol.27
, Issue.37
, pp. 9855-9865
-
-
L-Y, C.1
J-K, C.2
Chu, D.3
C-F, C.4
Tsaur, M.-L.5
-
107
-
-
79959398966
-
v4 channels underlie the subthreshold-operating A-type K-current in nociceptive dorsal root ganglion neurons
-
v4 channels underlie the subthreshold-operating A-type K-current in nociceptive dorsal root ganglion neurons. Front. Mol. Neurosci. 2, 3 (2009).
-
(2009)
Front. Mol. Neurosci.
, vol.2
, pp. 3
-
-
Phuket, N.1
Ratanadilok, T.2
Covarrubias, M.3
-
108
-
-
67449113762
-
Plasticity and emerging role of BKCa channels in nociceptive control in neuropathic pain
-
Chen SR, Cai YQ, Pan HL. Plasticity and emerging role of BKCa channels in nociceptive control in neuropathic pain. J. Neurochem. 110 (1), 352-362 (2009).
-
(2009)
J. Neurochem.
, vol.110
, Issue.1
, pp. 352-362
-
-
Chen, S.R.1
Cai, Y.Q.2
Pan, H.L.3
-
110
-
-
51749096417
-
Characteristic of HCN channels and their participation in neuropathic pain
-
Recent review about hyperpolarization activated cyclic nucleotide gated cation channels structure and evidence of its role in neuropathic pain
-
Jiang YQ, Sun Q, Tu HY, Wan Y. Characteristic of HCN channels and their participation in neuropathic pain. Neurochem. Res. 33, 1979-1989 (2008). Recent review about hyperpolarization activated cyclic nucleotide gated cation channels structure and evidence of its role in neuropathic pain.
-
(2008)
Neurochem. Res.
, vol.33
, pp. 1979-1989
-
-
Jiang, Y.Q.1
Sun, Q.2
Tu, H.Y.3
Wan, Y.4
-
111
-
-
0017191157
-
Membrane currents in the rabbit sinoatrial node cell as studied by the double microelectrode method
-
Noma A, Irisawa H. Membrane currents in the rabbit sinoatrial node cell as studied by the double microelectrode method. Pflugers Arch. 364 (1), 45-52 (1976)
-
(1976)
Pflugers Arch.
, vol.364
, Issue.1
, pp. 45-52
-
-
Noma, A.1
Irisawa, H.2
-
112
-
-
0037443129
-
Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain
-
Chaplan SR, Guo HQ, Lee DH et al. Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain. J. Neurosci. 23, 1169-1178 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 1169-1178
-
-
Chaplan, S.R.1
Guo, H.Q.2
Lee, D.H.3
-
113
-
-
12844281879
-
Inhibition of hyperpolarization-activated current by ZD7288 suppresses ectopic discharges of injured dorsal root ganglion neurons in a rat model of neuropathic pain
-
Sun Q, Xing GG, Tu HY, Han JS, Wan Y. Inhibition of hyperpolarization- activated current by ZD7288 suppresses ectopic discharges of injured dorsal root ganglion neurons in a rat model of neuropathic pain. Brain Res. 1032 (1-3), 63-69 (2005).
-
(2005)
Brain Res.
, vol.1032
, Issue.1-3
, pp. 63-69
-
-
Sun, Q.1
Xing, G.G.2
Tu, H.Y.3
Han, J.S.4
Wan, Y.5
-
114
-
-
0020645416
-
A voltage-clamp analysis of inward (anomalous) rectification in mouse spinal sensory ganglion neurones
-
Mayer ML, Westbrook GL. A voltage-clamp analysis of inward (anomalous) rectification in mouse spinal sensory ganglion neurones. J. Physiol. 340, 19-45 (1983).
-
(1983)
J. Physiol.
, vol.340
, pp. 19-45
-
-
Mayer, M.L.1
Westbrook, G.L.2
-
115
-
-
43949146603
-
Hyperpolarization activated cyclic nucleotide-gated channel mRNA and protein expression in large versus small diameter dorsal root ganglion neurons: Correlation with hyperpolarization-activated current gating
-
Kouranova EV, Strassle BW, Ring RH, Bowlby MR, Vasilyev DV. Hyperpolarization Activated cyclic nucleotide-gated channel mRNA and protein expression in large versus small diameter dorsal root ganglion neurons: correlation with hyperpolarization-activated current gating. Neuroscience 153 (4), 1008-1019 (2008).
-
(2008)
Neuroscience
, vol.153
, Issue.4
, pp. 1008-1019
-
-
Kouranova, E.V.1
Strassle, B.W.2
Ring, R.H.3
Bowlby, M.R.4
Vasilyev, D.V.5
-
116
-
-
2542423713
-
Hyperpolarization-activated, cyclic nucleotide-gated cation channels: Roles in the differential electrophysiological properties of rat primary afferent neurons
-
Tu H, Deng L, Sun Q, Yao L, Han JS, Wan Y. Hyperpolarization-activated, cyclic nucleotide-gated cation channels: roles in the differential electrophysiological properties of rat primary afferent neurons. J. Neurosci. Res. 76 (5), 713-722 (2004).
-
(2004)
J. Neurosci. Res.
, vol.76
, Issue.5
, pp. 713-722
-
-
Tu, H.1
Deng, L.2
Sun, Q.3
Yao, L.4
Han, J.S.5
Wan, Y.6
-
117
-
-
33748745543
-
Hyperoplarization-activated and cyclic nucleotide-gated cation channel subunit 2 ion channels modulate synaptic transmission from nociceptive primary afferents containing substance P to secondary sensory neurons in laminae I-IIo of the rodent spinal dorsal horn
-
Papp I, Szucs P, Hollo K, Erdelyi F, Szabo G, Antal M. Hyperoplarization-activated and cyclic nucleotide-gated cation channel subunit 2 ion channels modulate synaptic transmission from nociceptive primary afferents containing substance P to secondary sensory neurons in laminae I-IIo of the rodent spinal dorsal horn. Eur. J. Neurosci. 24, 1341-1352 (2006).
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 1341-1352
-
-
Papp, I.1
Szucs, P.2
Hollo, K.3
Erdelyi, F.4
Szabo, G.5
Antal, M.6
-
118
-
-
33846314359
-
Role of peripheral hyperpolarization-activate cyclic nucleotide-modulated channel pacemaker channels in acute and chronic pain models in the rat
-
Luo L, Chang L, Brown SM et al. Role of peripheral hyperpolarization- activate cyclic nucleotide-modulated channel pacemaker channels in acute and chronic pain models in the rat. Neuroscience 144, 1477-1485 (2007).
-
(2007)
Neuroscience
, vol.144
, pp. 1477-1485
-
-
Luo, L.1
Chang, L.2
Brown, S.M.3
-
119
-
-
17644421106
-
CAMP-mediated mechanism for pain sensitization during opioid withdrawal
-
Bie B, Peng Y, Zhang Y, Pan ZZ. cAMP-mediated mechanism for pain sensitization during opioid withdrawal. J. Neurosci. 25 (15), 3824-3832 (2005).
-
(2005)
J. Neurosci.
, vol.25
, Issue.15
, pp. 3824-3832
-
-
Bie, B.1
Peng, Y.2
Zhang, Y.3
Pan, Z.Z.4
-
120
-
-
0033629748
-
Chronic morphine increases GABA tone on serotoninergic neurons of the dorsal raphe nucleus: Association with an upregulation of the cyclic AMP pathway
-
Jolas T, Nestler EJ, Aghajanian GK. Chronic morphine increases GABA tone on serotoninergic neurons of the dorsal raphe nucleus: association with an upregulation of the cyclic AMP pathway. Neuroscience 95 (2), 433-443 (2000).
-
(2000)
Neuroscience
, vol.95
, Issue.2
, pp. 433-443
-
-
Jolas, T.1
Nestler, E.J.2
Aghajanian, G.K.3
-
121
-
-
33748794961
-
The role of pacemaker currents in neuropathic pain
-
Brown SM, Dubin AE, Chaplan SR. The role of pacemaker currents in neuropathic pain. Pain Practice 4 (3), 182-193 (2004).
-
(2004)
Pain Practice
, vol.4
, Issue.3
, pp. 182-193
-
-
Brown, S.M.1
Dubin, A.E.2
Chaplan, S.R.3
-
122
-
-
0020967907
-
Autotomy after nerve injury and its relation to spontaneous discharge originating in nerve-end neuromas
-
Devor M, Raber P. Autotomy after nerve injury and its relation to spontaneous discharge originating in nerve-end neuromas. Behav. Neurol. Biol. 37, 276-283 (1983).
-
(1983)
Behav. Neurol. Biol.
, vol.37
, pp. 276-283
-
-
Devor, M.1
Raber, P.2
-
123
-
-
0034175686
-
Tactile allodynia in the absence of C-fiber activation: Altered firing properties of DRG neurons following spinal nerve injury
-
Liu CN, Wall PD, Ben-Dor E, Michaelis M, Amir R, Devor M. Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury. Pain 85, 503-521 (2000).
-
(2000)
Pain
, vol.85
, pp. 503-521
-
-
Liu, C.N.1
Wall, P.D.2
Ben-Dor, E.3
Michaelis, M.4
Amir, R.5
Devor, M.6
-
124
-
-
0029893712
-
Abnormal discharge originates at the site of nerve injury in experimental constriction neuropathy (CCI) in the rat
-
Tal M, Eliav E. Abnormal discharge originates at the site of nerve injury in experimental constriction neuropathy (CCI) in the rat. Pain 64 (3), 511-518 (1996).
-
(1996)
Pain
, vol.64
, Issue.3
, pp. 511-518
-
-
Tal, M.1
Eliav, E.2
-
125
-
-
0026767449
-
Onset of a painful peripheral neuropathy in rat: A partial and differential deafferentation and spontaneous discharge in A-β and A-δ primary afferent neurons
-
Kajander KC, Bennett GJ. Onset of a painful peripheral neuropathy in rat: a partial and differential deafferentation and spontaneous discharge in A-β and A-δ primary afferent neurons. J. Neurophysiol. 68 (3), 734-744 (1992).
-
(1992)
J. Neurophysiol.
, vol.68
, Issue.3
, pp. 734-744
-
-
Kajander, K.C.1
Bennett, G.J.2
-
126
-
-
0033391029
-
Mechanical and thermal hyperalgesia and ectopic neuronal discharge after chronic compression of dorsal root ganglia
-
Song XJ, Hu SJ, Greenquist K W, Zhang JM, LaMotte RH. Mechanical and thermal hyperalgesia and ectopic neuronal discharge after chronic compression of dorsal root ganglia. J. Neurophysiol. 82 (6), 3347-3358 (1999).
-
(1999)
J. Neurophysiol.
, vol.82
, Issue.6
, pp. 3347-3358
-
-
Song, X.J.1
Hu, S.J.2
Greenquist, K.W.3
Zhang, J.M.4
LaMotte, R.H.5
-
127
-
-
68849090808
-
Involvement of hyperpolarization activated cyclic nucleotide-gated cation channels in dorsal root ganglion in neuropathic pain
-
Wan Y. Involvement of hyperpolarization activated cyclic nucleotide-gated cation channels in dorsal root ganglion in neuropathic pain. Acta Physiol. Sinica 60 (5), 579-580 (2008).
-
(2008)
Acta Physiol. Sinica
, vol.60
, Issue.5
, pp. 579-580
-
-
Wan, Y.1
-
128
-
-
0037444668
-
Upregulation of the hyperpolarization activated cation current after chronic compression of the dorsal root ganglion
-
Yao H, Donnelly DF, Ma C, LaMotte RH. Upregulation of the hyperpolarization activated cation current after chronic compression of the dorsal root ganglion. J. Neurosci. 23, 2069-2074 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 2069-2074
-
-
Yao, H.1
Donnelly, D.F.2
Ma, C.3
LaMotte, R.H.4
-
129
-
-
47049086068
-
Axonal accumulation of hyperpolarization-activated cyclic nucleotide-gated cation channels contributes to mechanical allodynia after peripheral nerve injury in rat
-
Jiang YQ, Xing GG, Wang SL et al. Axonal accumulation of hyperpolarization-activated cyclic nucleotide-gated cation channels contributes to mechanical allodynia after peripheral nerve injury in rat. Pain 137, 495-506 (2008).
-
(2008)
Pain
, vol.137
, pp. 495-506
-
-
Jiang, Y.Q.1
Xing, G.G.2
Wang, S.L.3
-
130
-
-
21544472648
-
Hyperpolarization-activated, cationnonselective, cyclic nucleotide-modulated channel blockade alleviates mechanical allodynia and suppresses ectopic discharge in spinal nerve ligated rats
-
Lee DH, Chang L, Sorkin LS, Chaplan SR. Hyperpolarization-activated, cationnonselective, cyclic nucleotide-modulated channel blockade alleviates mechanical allodynia and suppresses ectopic discharge in spinal nerve ligated rats. J. Pain. 6 (7), 417-424 (2005).
-
(2005)
J. Pain
, vol.6
, Issue.7
, pp. 417-424
-
-
Lee, D.H.1
Chang, L.2
Sorkin, L.S.3
Chaplan, S.R.4
-
131
-
-
16844366973
-
Homo- and heteromeric assembly of TRPV channel subunits
-
Hellwig N, Albrech N, Harteneck C, Schultz G, Schaefer M. Homo- and heteromeric assembly of TRPV channel subunits. J. Cell Sci. 118, 917-928 (2005).
-
(2005)
J. Cell. Sci.
, vol.118
, pp. 917-928
-
-
Hellwig, N.1
Albrech, N.2
Harteneck, C.3
Schultz, G.4
Schaefer, M.5
-
133
-
-
33644875032
-
The TRP superfamily of cation channels
-
Montell C. The TRP superfamily of cation channels. Science STKE 272, 3 (2005).
-
(2005)
Science STKE
, vol.272
, pp. 3
-
-
Montell, C.1
-
134
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389, 816-824 (1997).
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
135
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M, Caterina MJ, Malmberg AB et al. The cloned capsaicin receptor integrates multiple pain-producing stimuli. aNeuron 21, 531-543 (1998).
-
(1998)
ANeuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
-
136
-
-
25644433563
-
Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism
-
Xu H, Blair NT, Clapham DE. Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J. Neurosci. 25, 8924-8937 (2005).
-
(2005)
J. Neurosci.
, vol.25
, pp. 8924-8937
-
-
Xu, H.1
Blair, N.T.2
Clapham, D.E.3
-
137
-
-
20144371097
-
The pungency of garlic: Activation of TRPA1 and TRPV1 in response to allicin
-
Macpherson LJ, Geierstanger BH, Viswanath V et al. The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr. Biol. 15, 929-934 (2005).
-
(2005)
Curr. Biol.
, vol.15
, pp. 929-934
-
-
Macpherson, L.J.1
Geierstanger, B.H.2
Viswanath, V.3
-
138
-
-
33750257552
-
Nitric oxide activates TRP channels by cysteine S-nitrosylation
-
Yoshida T, Inoue R, Morii T et al. Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nat. Chem. Biol. 2 (11), 596-607 (2006).
-
(2006)
Nat. Chem. Biol.
, vol.2
, Issue.11
, pp. 596-607
-
-
Yoshida, T.1
Inoue, R.2
Morii, T.3
-
139
-
-
85047696992
-
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1
-
Trevisani M, Smart D, Gunthorpe MJ et al. Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat. Neurosci. 5, 546-551 (2002).
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 546-551
-
-
Trevisani, M.1
Smart, D.2
Gunthorpe, M.J.3
-
140
-
-
22844444276
-
Sensitization of vanilloid receptor involves an increase in the phosphorylated form of the channel
-
Lee SY, Lee JH, Kang KK, Hwang SY, Choi KD, Oh U. Sensitization of vanilloid receptor involves an increase in the phosphorylated form of the channel. Arch. Pharm. Res. 28, 405-412 (2005).
-
(2005)
Arch. Pharm. Res.
, vol.28
, pp. 405-412
-
-
Lee, S.Y.1
Lee, J.H.2
Kang, K.K.3
Hwang, S.Y.4
Choi, K.D.5
Oh, U.6
-
141
-
-
0035940785
-
The distribution and regulation of vanilloid receptor VR1 and VR1 5' splice variant RNA expression in rat
-
Sanchez JF, Krause JE, Cortright DN. The distribution and regulation of vanilloid receptor VR1 and VR1 5' splice variant RNA expression in rat. Neuroscience 107, 373-381 (2001).
-
(2001)
Neuroscience
, vol.107
, pp. 373-381
-
-
Sanchez, J.F.1
Krause, J.E.2
Cortright, D.N.3
-
142
-
-
0034926291
-
The vanilloid receptor: A molecular gateway to the pain pathway
-
Caterina MJ, Julius D. The vanilloid receptor: a molecular gateway to the pain pathway. Annu. Rev. Neurosci. 24, 487-517 (2001).
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 487-517
-
-
Caterina, M.J.1
Julius, D.2
-
143
-
-
0034954583
-
VR1 protein expression increases in undamaged DRG neurons after partial nerve injury
-
Hudson LJ, Bevan S, Wotherspoon G, Gentry C, Fox A, Winter J. VR1 protein expression increases in undamaged DRG neurons after partial nerve injury. Eur. J. Neurosci. 13, 2105-2114 (2001).
-
(2001)
Eur. J. Neurosci.
, vol.13
, pp. 2105-2114
-
-
Hudson, L.J.1
Bevan, S.2
Wotherspoon, G.3
Gentry, C.4
Fox, A.5
Winter, J.6
-
144
-
-
0034646740
-
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
-
Caterina MJ, Leffler A, Malmberg AB et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288, 306-313 (2000).
-
(2000)
Science
, vol.288
, pp. 306-313
-
-
Caterina, M.J.1
Leffler, A.2
Malmberg, A.B.3
-
145
-
-
0034636441
-
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
-
Davis JB, Gray J, Gunthorpe MJ et al. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 405, 183-187 (2000).
-
(2000)
Nature
, vol.405
, pp. 183-187
-
-
Davis, J.B.1
Gray, J.2
Gunthorpe, M.J.3
-
146
-
-
33845343959
-
Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1
-
Christoph T, Gillen C, Mika J et al. Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1. Neurochem. Int. 50, 281-290 (2007).
-
(2007)
Neurochem. Int.
, vol.50
, pp. 281-290
-
-
Christoph, T.1
Gillen, C.2
Mika, J.3
-
147
-
-
33749050585
-
Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo
-
Christoph T, Grunweller A, Mika J et al. Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo. Biochem. Biophys. Res. Commun. 350, 238-243 (2006).
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.350
, pp. 238-243
-
-
Christoph, T.1
Grunweller, A.2
Mika, J.3
-
148
-
-
27144440511
-
Involvement of an increased spinal TRPV1 sensitization through its upregulation in mechanical allodynia of CCI rats
-
Kanai Y, Nakazato E, Fujiuchi A, Hara T, Imai A. Involvement of an increased spinal TRPV1 sensitization through its upregulation in mechanical allodynia of CCI rats. Neuropharmacol. 49, 977-984 (2005).
-
(2005)
Neuropharmacol.
, vol.49
, pp. 977-984
-
-
Kanai, Y.1
Nakazato, E.2
Fujiuchi, A.3
Hara, T.4
Imai, A.5
-
149
-
-
0038128285
-
N- (4-Tertiarybutylphenyl) -4- (3-chloropyridin-2-yl) tetrahydropyrazine-1 (2H) -carbox-amide (BCTC), a novel, orally-effective vanilloid receptor 1 antagonist with analgesic properties: II. In vivo characterization in rat models of inflammatory and neuropathic pain
-
Pomonis JD, Harrison JE, Mark L, Bristol DR, Valenzano KJ, Walker K. N- (4-Tertiarybutylphenyl) -4- (3-chloropyridin-2-yl) tetrahydropyrazine-1 (2H) -carbox-amide (BCTC), a novel, orally-effective vanilloid receptor 1 antagonist with analgesic properties: II. In vivo characterization in rat models of inflammatory and neuropathic pain. J. Pharmacol. Exp. Ther. 306, 387-393 (2003).
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 387-393
-
-
Pomonis, J.D.1
Harrison, J.E.2
Mark, L.3
Bristol, D.R.4
Valenzano, K.J.5
Walker, K.6
-
150
-
-
23044496253
-
A-425619 [1-isoquinolin-5-yl-3- (4-trifluoromethyl-benzyl) -urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats
-
Honore P, Wismer CT, Mikusa J et al. A-425619 [1-isoquinolin-5-yl-3- (4-trifluoromethyl-benzyl) -urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats. J. Pharmacol. Exp. Ther. 314, 410-421 (2005).
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.314
, pp. 410-421
-
-
Honore, P.1
Wismer, C.T.2
Mikusa, J.3
-
151
-
-
18444408683
-
TRPV3 is a temperature sensitive vanilloid receptor-like protein
-
Smith GD, Gunthorpe MJ, Kelsell RE et al. TRPV3 is a temperature sensitive vanilloid receptor-like protein. Nature 418, 186-190 (2002).
-
(2002)
Nature
, vol.418
, pp. 186-190
-
-
Smith, G.D.1
Gunthorpe, M.J.2
Kelsell, R.E.3
-
152
-
-
0037062915
-
TRPV3 is a calcium-permeable temperature-sensitive cation channel
-
Xu H, Ramsey IS, Kotecha SA et al. TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature 418, 181-186 (2002).
-
(2002)
Nature
, vol.418
, pp. 181-186
-
-
Xu, H.1
Ramsey, I.S.2
Kotecha, S.A.3
-
153
-
-
33744916763
-
Potentiation of TRPV3 channel function by unsaturated fatty acids
-
Hu HZ, Xiao R, Wang C et al. Potentiation of TRPV3 channel function by unsaturated fatty acids. J. Cell. Physiol. 208, 201-212 (2006).
-
(2006)
J. Cell. Physiol.
, vol.208
, pp. 201-212
-
-
Hu, H.Z.1
Xiao, R.2
Wang, C.3
-
154
-
-
0037077041
-
A heat-sensitive TRP channel expressed in keratinocytes
-
Peier AM, Reeve AJ, Andersson DA et al. A heat-sensitive TRP channel expressed in keratinocytes. Science 296, 2046-2049 (2002).
-
(2002)
Science
, vol.296
, pp. 2046-2049
-
-
Peier, A.M.1
Reeve, A.J.2
Andersson, D.A.3
-
155
-
-
14644392188
-
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin
-
Moqrich A, Hwang SW, Earley TJ et al. Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin. Science 307, 1468-1472 (2005).
-
(2005)
Science
, vol.307
, pp. 1468-1472
-
-
Moqrich, A.1
Hwang, S.W.2
Earley, T.J.3
-
156
-
-
68149151528
-
GRC-15133: A novel, selective TRPV3 antagonist with antihyperalgesic effects in inflammatory and neuropathic pain
-
Philadelphia, PA, USA
-
Gullapalli S, Thomas A, Rao P, Kattige V, Gudi GS, Khairatkar-Joshi N. GRC-15133: a novel, selective TRPV3 antagonist with antihyperalgesic effects in inflammatory and neuropathic pain. CHI's World Pharmaceutical Congress, Philadelphia, PA, USA, 2008.
-
(2008)
CHI's World Pharmaceutical Congress
-
-
Gullapalli, S.1
Thomas, A.2
Rao, P.3
Kattige, V.4
Gudi, G.S.5
Khairatkar-Joshi, N.6
-
157
-
-
0033548702
-
An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts
-
Jaquemar D, Schenker, Trueb B. An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J. Biol. Chem. 274, 7325-7333 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7325-7333
-
-
Jaquemar, D.1
Schenker2
Trueb, B.3
-
158
-
-
1842475312
-
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
-
Bandell M, Story GM, Hwang SW et al. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41, 849-857 (2004).
-
(2004)
Neuron
, vol.41
, pp. 849-857
-
-
Bandell, M.1
Story, G.M.2
Hwang, S.W.3
-
159
-
-
38549092780
-
Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1)
-
Taylor-Clark TE, Undem BJ, Macglashan DW, Ghatta S, Carr MJ, McAlexander MA. Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1). Mol. Pharmacol. 73, 274-281 (2008).
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 274-281
-
-
Taylor-Clark, T.E.1
Undem, B.J.2
Macglashan, D.W.3
Ghatta, S.4
Carr, M.J.5
McAlexander, M.A.6
-
160
-
-
0345616438
-
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
-
Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacker J, Hricik TR. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112, 819-829 (2003).
-
(2003)
Cell.
, vol.112
, pp. 819-829
-
-
Story, G.M.1
Peier, A.M.2
Reeve, A.J.3
Eid, S.R.4
Mosbacker, J.5
Hricik, T.R.6
-
161
-
-
24644462327
-
TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury
-
Obata K, Katsura H, Mizushima T, Yamanaka H, Kobayashi K, Day Y. TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury. J. Clin. Invest. 115, 2393-2401 (2005).
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2393-2401
-
-
Obata, K.1
Katsura, H.2
Mizushima, T.3
Yamanaka, H.4
Kobayashi, K.5
Day, Y.6
-
162
-
-
33646045075
-
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
-
Bautista DM, Jordt SE, Nikai T, Tsuruda PR, Read AJ, Poblete J. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 124, 1269-1282 (2006).
-
(2006)
Cell.
, vol.124
, pp. 1269-1282
-
-
Bautista, D.M.1
Jordt, S.E.2
Nikai, T.3
Tsuruda, P.R.4
Read, A.J.5
Poblete, J.6
-
163
-
-
33746083982
-
Antisense knock-down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats
-
Katsura H, Obata K, Mizushima T, Yamanaka H, Kobayashi K, Day Y. Antisense knock-down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats. Exp. Neurol. 200, 112-113 (2006).
-
(2006)
Exp. Neurol.
, vol.200
, pp. 112-113
-
-
Katsura, H.1
Obata, K.2
Mizushima, T.3
Yamanaka, H.4
Kobayashi, K.5
Day, Y.6
-
164
-
-
58049096661
-
Kainate receptors: Pharmacology, function and therapeutic potential
-
Jane DE, Lodge D, Collingridge GL. Kainate receptors: pharmacology, function and therapeutic potential. Neuropharmacol. 56, 90-113 (2009).
-
(2009)
Neuropharmacol.
, vol.56
, pp. 90-113
-
-
Jane, D.E.1
Lodge, D.2
Collingridge, G.L.3
-
165
-
-
38949175353
-
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
-
Petrus M, Peier AM, Bandell M et al. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol. Pain 3, 40 (2007).
-
(2007)
Mol. Pain
, vol.3
, pp. 40
-
-
Petrus, M.1
Peier, A.M.2
Bandell, M.3
-
167
-
-
56449110894
-
HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathyinduced mechanical hypersensitivity
-
Eid SR, Crown ED, Moore EL et al. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathyinduced mechanical hypersensitivity. Mol. Pain 4, 48 (2008).
-
(2008)
Mol. Pain
, vol.4
, pp. 48
-
-
Eid, S.R.1
Crown, E.D.2
Moore, E.L.3
-
168
-
-
18344386202
-
A TRP channel that senses cold stimuli and menthol
-
Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM. A TRP channel that senses cold stimuli and menthol. Cell 108, 705-715 (2002).
-
(2002)
Cell.
, vol.108
, pp. 705-715
-
-
Peier, A.M.1
Moqrich, A.2
Hergarden, A.C.3
Reeve, A.J.4
Andersson, D.A.5
Story, G.M.6
-
169
-
-
34447542435
-
The menthol receptor TRPM8 is the principal detector of environmental cold
-
Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL. The menthol receptor TRPM8 is the principal detector of environmental cold. Nature 448, 204-208 (2007).
-
(2007)
Nature
, vol.448
, pp. 204-208
-
-
Bautista, D.M.1
Siemens, J.2
Glazer, J.M.3
Tsuruda, P.R.4
Basbaum, A.I.5
Stucky, C.L.6
-
170
-
-
0037034931
-
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
-
McKemy DD, Neuhausser WM, Julius D. Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416, 52-58 (2007).
-
(2007)
Nature
, vol.416
, pp. 52-58
-
-
McKemy, D.D.1
Neuhausser, W.M.2
Julius, D.3
-
171
-
-
28844471303
-
Distinct expression of TRPM8, TRPA1 and TRPV1 mRNAs in rat primary afferent neurons with Aδ/C-fibers and colocalization with Trk receptors
-
Kobayashi A, Fukuoka T, Obata H et al. Distinct expression of TRPM8, TRPA1 and TRPV1 mRNAs in rat primary afferent neurons with Aδ/C-fibers and colocalization with Trk receptors. J. Comp. Neurol. 493, 596-606 (2005).
-
(2005)
J. Comp. Neurol.
, vol.493
, pp. 596-606
-
-
Kobayashi, A.1
Fukuoka, T.2
Obata, H.3
-
172
-
-
34247472646
-
Attenuated cold sensitivity in TRPM8 null mice
-
Colburn RW, Lubin ML., Stone DJ, Wang Y, Lawrence D, D'Andrea MR. Attenuated cold sensitivity in TRPM8 null mice. Neuron 54, 379-386 (2007).
-
(2007)
Neuron
, vol.54
, pp. 379-386
-
-
Colburn, R.W.1
Lubin, M.L.2
Stone, D.J.3
Wang, Y.4
Lawrence, D.5
D'Andrea, M.R.6
-
173
-
-
34247487011
-
TRPM8 is required for cold sensation in mice
-
Dhaka A, Murray AN, Mathur J, Earley TJ, Petrus MJ, Patapoutian A. TRPM8 is required for cold sensation in mice. Neuron 54, 371-378 (2007).
-
(2007)
Neuron
, vol.54
, pp. 371-378
-
-
Dhaka, A.1
Murray, A.N.2
Mathur, J.3
Earley, T.J.4
Petrus, M.J.5
Patapoutian, A.6
-
174
-
-
33747179334
-
Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain
-
Proudfoot CJ, Garry EM, Cottrell DF et al. Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain. Curr. Biol. 16, 1591-1605 (2006).
-
(2006)
Curr. Biol.
, vol.16
, pp. 1591-1605
-
-
Proudfoot, C.J.1
Garry, E.M.2
Cottrell, D.F.3
-
175
-
-
37249065119
-
TRPM8 mechanism of cold allodynia after chronic nerve injury
-
Xing H, Chen M, Ling J, Tan W, Gu JG. TRPM8 mechanism of cold allodynia after chronic nerve injury. J. Neurosci. 2 7, 13680-13690 (2007).
-
(2007)
J. Neurosci.
, vol.2
, Issue.7
, pp. 13680-13690
-
-
Xing, H.1
Chen, M.2
Ling, J.3
Tan, W.4
Gu, J.G.5
-
176
-
-
70350212466
-
The contribution of TRPM8 and TRPA1 channels to cold allodynia and neuropathic pain
-
Caspani O, Zurborg S, Labuz D, Heppenstall PA. The contribution of TRPM8 and TRPA1 channels to cold allodynia and neuropathic pain. PloS ONE 4 (10), e7383 (2009).
-
(2009)
PloS ONE
, vol.4
, Issue.10
-
-
Caspani, O.1
Zurborg, S.2
Labuz, D.3
Heppenstall, P.A.4
-
177
-
-
2442642767
-
Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse?
-
Szallasi A, Appendino G. Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse? J. Med. Chem. 47 (11), 2717-2723 (2004).
-
(2004)
J. Med. Chem.
, vol.47
, Issue.11
, pp. 2717-2723
-
-
Szallasi, A.1
Appendino, G.2
-
178
-
-
34250201413
-
The potential of transient receptor potential vanilloid type 1 channel modulators for the treatment of pain
-
Westaway SM. The potential of transient receptor potential vanilloid type 1 channel modulators for the treatment of pain. J. Med. Chem. 50, 2589-2596 (2007).
-
(2007)
J. Med. Chem.
, vol.50
, pp. 2589-2596
-
-
Westaway, S.M.1
-
179
-
-
34248138496
-
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
-
Szallasi A, Cortright DN, Blum CA, Eid SR. The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat. Rev. Drug Discov. 6, 357-372 (2007).
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 357-372
-
-
Szallasi, A.1
Cortright, D.N.2
Blum, C.A.3
Eid, S.R.4
-
180
-
-
39449097036
-
TRPV1 receptors in the central nervous system: Potential for previously unforeseen therapeutic applications
-
Starowicz K, Cristino L, DiMarzo V. TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications. Curr. Phar. Des. 14, 42-54 (2008).
-
(2008)
Curr. Phar. Des.
, vol.14
, pp. 42-54
-
-
Starowicz, K.1
Cristino, L.2
DiMarzo, V.3
-
181
-
-
63649126112
-
Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks
-
Wong GY, Gavva NR. Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: recent advances and setbacks. Brain Res. Rev. 60, 267-277 (2009).
-
(2009)
Brain Res. Rev.
, vol.60
, pp. 267-277
-
-
Wong, G.Y.1
Gavva, N.R.2
-
182
-
-
54349127771
-
Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1
-
Gavva NR. Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1. Trends. Pharm. Sci. 29 (11), 550-557 (2008).
-
(2008)
Trends. Pharm. Sci.
, vol.29
, Issue.11
, pp. 550-557
-
-
Gavva, N.R.1
-
183
-
-
22944483793
-
Cellular signaling pathways of spinal pain neuroplasticity as targets for analgesic development
-
Salter M. W. Cellular signaling pathways of spinal pain neuroplasticity as targets for analgesic development. Curr. Top. Med. Chem. 5, 557-567 (2005).
-
(2005)
Curr. Top. Med. Chem.
, vol.5
, pp. 557-567
-
-
Salter, M.W.1
-
185
-
-
58049126584
-
A nomenclature for ligand-gated ion channels
-
Collingridge GL, Olsen RW, Peters J, Spedding M. A nomenclature for ligand-gated ion channels. Neuropharmacol. 56, 2-5 (2009).
-
(2009)
Neuropharmacol.
, vol.56
, pp. 2-5
-
-
Collingridge, G.L.1
Olsen, R.W.2
Peters, J.3
Spedding, M.4
-
186
-
-
2342462388
-
Structure and function of glutamate receptor ion channels
-
Mayer ML, Armstrong N. Structure and function of glutamate receptor ion channels. Annu. Rev. Physiol. 66, 161-181 (2004).
-
(2004)
Annu. Rev. Physiol.
, vol.66
, pp. 161-181
-
-
Mayer, M.L.1
Armstrong, N.2
-
187
-
-
33846920665
-
NMDA receptor subunits: Function and pharmacology
-
Paoletti P, Neyton J. NMDA receptor subunits: function and pharmacology. Curr. Opin. Pharmacol. 7 (1), 39-47 (2007).
-
(2007)
Curr. Opin. Pharmacol.
, vol.7
, Issue.1
, pp. 39-47
-
-
Paoletti, P.1
Neyton, J.2
-
188
-
-
34250158705
-
N-methyl-D-aspartate antagonists and neuropathic pain: The search for relief
-
Excellent review on the pros and cons of different N-methyl-d-aspartate antagonists in neuropathic pain
-
Childers WE Jr, Baudy RB. N-methyl-D-aspartate antagonists and neuropathic pain: the search for relief. J. Med. Chem. 50 (11), 2557-2562 (2007). Excellent review on the pros and cons of different N-methyl-d-aspartate antagonists in neuropathic pain.
-
(2007)
J. Med. Chem.
, vol.50
, Issue.11
, pp. 2557-2562
-
-
Childers Jr., W.E.1
Baudy, R.B.2
-
190
-
-
0030000101
-
Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats
-
Zhou S, Bonasera L, Carlton SM. Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats. Neuroreport 7, 895-900 (1996).
-
(1996)
Neuroreport
, vol.7
, pp. 895-900
-
-
Zhou, S.1
Bonasera, L.2
Carlton, S.M.3
-
191
-
-
0026640290
-
The contribution of excitatory amino acids to central sensitization and persistent nociception after formalininduced tissue injury
-
Coderre TJ, Melzack R. The contribution of excitatory amino acids to central sensitization and persistent nociception after formalininduced tissue injury. J. Neurosci. 12, 3665-3670 (1992).
-
(1992)
J. Neurosci.
, vol.12
, pp. 3665-3670
-
-
Coderre, T.J.1
Melzack, R.2
-
192
-
-
0037135250
-
Glutamate-induced currents reveal three functionally distinct NMDA receptor populations in rat dorsal horn. Effects of pheriperal nerve lesion and inflammation
-
Karlsson U, Sjodin J, Angeby K et al. Glutamate-induced currents reveal three functionally distinct NMDA receptor populations in rat dorsal horn. Effects of pheriperal nerve lesion and inflammation. Neuroscience 112, 861-868 (2002).
-
(2002)
Neuroscience
, vol.112
, pp. 861-868
-
-
Karlsson, U.1
Sjodin, J.2
Angeby, K.3
-
193
-
-
0023605956
-
Evidence for involvement of N-methylaspartate receptors in "windup" of class 2 neurones in the dorsal horn of the rat
-
Davies SN, Lodge D. Evidence for involvement of N-methylaspartate receptors in "windup" of class 2 neurones in the dorsal horn of the rat. Brain Res. 424, 402-406 (1987).
-
(1987)
Brain Res.
, vol.424
, pp. 402-406
-
-
Davies, S.N.1
Lodge, D.2
-
194
-
-
0023189510
-
Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurons following C fibre stimulation
-
Dickenson AH, Sullivan AF. Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurons following C fibre stimulation. Neuropharmacol. 26, 1235-1238 (1987).
-
(1987)
Neuropharmacol.
, vol.26
, pp. 1235-1238
-
-
Dickenson, A.H.1
Sullivan, A.F.2
-
195
-
-
33646596268
-
N-methyl-D-aspartate receptor (NMDA) antagonists as potential pain therapeutics
-
Brown DG, Krupp JJ. N-methyl-D-aspartate receptor (NMDA) antagonists as potential pain therapeutics. Curr. Top. Med. Chem. 6, 749-770 (2006).
-
(2006)
Curr. Top. Med. Chem.
, vol.6
, pp. 749-770
-
-
Brown, D.G.1
Krupp, J.J.2
-
196
-
-
23844495851
-
NMDA antagonists and neuropathic pain - Multiple drug targets and multiple uses
-
Chizh BA, Headley PM. NMDA antagonists and neuropathic pain - multiple drug targets and multiple uses. Curr. Pharm. Des. 11, 2977-2994 (2005).
-
(2005)
Curr. Pharm. Des.
, vol.11
, pp. 2977-2994
-
-
Chizh, B.A.1
Headley, P.M.2
-
197
-
-
70350324907
-
Allosteric modulators of NR2B-containing NMDA receptors: Molecular mechanism and therapeutic potential
-
Mony L, Kew J N C, Gunthorpe MJ, Paoletti P. Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanism and therapeutic potential. Br. J. Pharmacol. 157, 1301-1317 (2009).
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 1301-1317
-
-
Mony, L.1
Kew, J.N.C.2
Gunthorpe, M.J.3
Paoletti, P.4
-
199
-
-
0141682535
-
Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit
-
Garry EM, Moss A, Rosie R et al. Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit. Mol. Cell. Neurosci. 24, 10-22 (2003).
-
(2003)
Mol. Cell. Neurosci.
, vol.24
, pp. 10-22
-
-
Garry, E.M.1
Moss, A.2
Rosie, R.3
-
200
-
-
0029779837
-
Upregulation of spinal glutamate receptors in chronic pain
-
Harris JA, Corsi M, Quartiroli M, Arban R, Bentivoglio M. Upregulation of spinal glutamate receptors in chronic pain. Neuroscience 74, 7-12 (1996).
-
(1996)
Neuroscience
, vol.74
, pp. 7-12
-
-
Harris, J.A.1
Corsi, M.2
Quartiroli, M.3
Arban, R.4
Bentivoglio, M.5
-
201
-
-
0034678026
-
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury
-
Bennett AD, Everhart AW, Hulsebosch CE. Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury. Brain Res. 859, 72-82 (2000).
-
(2000)
Brain Res.
, vol.859
, pp. 72-82
-
-
Bennett, A.D.1
Everhart, A.W.2
Hulsebosch, C.E.3
-
202
-
-
0036249632
-
The role of ionotropic glutamate receptors in nociception with special regard to the AMPA binding site
-
Szekely JI, Torok K, Maté G. The role of ionotropic glutamate receptors in nociception with special regard to the AMPA binding site. Curr. Pharm. Des. 8, 887-912 (2002).
-
(2002)
Curr. Pharm. Des.
, vol.8
, pp. 887-912
-
-
Szekely, J.I.1
Torok, K.2
Maté, G.3
-
203
-
-
0027404879
-
GYKI52466, a 2, 3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses
-
Donevan SD, Rogawski MA. GYKI52466, a 2, 3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron 10, 51-59 (1993).
-
(1993)
Neuron
, vol.10
, pp. 51-59
-
-
Donevan, S.D.1
Rogawski, M.A.2
-
204
-
-
0033830023
-
Effects of the 2-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid/kainate antagonist LY293558 on spontaneous and evoked postoperative pain
-
Gilron I, Max MB, Lee G et al. Effects of the 2-amino-3-hydroxy-5-methyl- 4-isoazolepropionic acid/kainate antagonist LY293558 on spontaneous and evoked postoperative pain. Clin. Pharmacol. Ther. 68, 320-327 (2000).
-
(2000)
Clin. Pharmacol. Ther.
, vol.68
, pp. 320-327
-
-
Gilron, I.1
Max, M.B.2
Lee, G.3
-
205
-
-
63849275646
-
The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: A randomized, doubleblind, placebo-controlled, three-way crossover study
-
Gormsen L, Finnerup NB, Almqvist PM, Jensen TS. The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, doubleblind, placebo-controlled, three-way crossover study. Anesth. Analg. 108, 1311-1319 (2009).
-
(2009)
Anesth. Analg.
, vol.108
, pp. 1311-1319
-
-
Gormsen, L.1
Finnerup, N.B.2
Almqvist, P.M.3
Jensen, T.S.4
-
206
-
-
0027421810
-
AMPA, KA and NMDA receptors are expressed in the rat DRG neurons
-
Sato K, Kiyama H, Park HT, Tohyama M. AMPA, KA and NMDA receptors are expressed in the rat DRG neurons. Neuroreport 4, 1263-1265 (1993).
-
(1993)
Neuroreport
, vol.4
, pp. 1263-1265
-
-
Sato, K.1
Kiyama, H.2
Park, H.T.3
Tohyama, M.4
-
207
-
-
77953432157
-
Parenterally administered kainic acid induces a persistent hyperalgesia in the mouse and rat
-
Giovengo SL, Kitto KF, Kurtz HJ, Velazquez RA, Larson AA. Parenterally administered kainic acid induces a persistent hyperalgesia in the mouse and rat. Pain 111, 151-161 (1999).
-
(1999)
Pain
, vol.111
, pp. 151-161
-
-
Giovengo, S.L.1
Kitto, K.F.2
Kurtz, H.J.3
Velazquez, R.A.4
Larson, A.A.5
-
208
-
-
0032191244
-
Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cord
-
Procter MJ, Houghton AK, Faber ES et al. Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cord. Neuropharmacol. 37, 1287-1297 (1998).
-
(1998)
Neuropharmacol.
, vol.37
, pp. 1287-1297
-
-
Procter, M.J.1
Houghton, A.K.2
Faber, E.S.3
-
209
-
-
1642296618
-
Pharmacological characterization of glutamatergic agonist and antagonist at recombinant human homomeric and heteromeric kainate receptors in vitro
-
Alt A, Weiss B, Ogden AM et al. Pharmacological characterization of glutamatergic agonist and antagonist at recombinant human homomeric and heteromeric kainate receptors in vitro. Neuropharmacol. 46, 793-806 (2004).
-
(2004)
Neuropharmacol.
, vol.46
, pp. 793-806
-
-
Alt, A.1
Weiss, B.2
Ogden, A.M.3
-
210
-
-
4344601743
-
The effect of kainate GluR5 receptor antagonist on responses of spinothalamic neurons in a model of peripheral neuropathy in primates
-
Palecek J, Neugebauer V, Carlton SM, Ivengar S, Willis WD. The effect of kainate GluR5 receptor antagonist on responses of spinothalamic neurons in a model of peripheral neuropathy in primates. Pain 111, 151-161 (2004).
-
(2004)
Pain
, vol.111
, pp. 151-161
-
-
Palecek, J.1
Neugebauer, V.2
Carlton, S.M.3
Ivengar, S.4
Willis, W.D.5
-
211
-
-
34249855741
-
Kainate receptors and pain: From dorsal root ganglion to the anterior cingulated cortex
-
Wu L, Ko SW, Zhuo M. Kainate receptors and pain: from dorsal root ganglion to the anterior cingulated cortex. Curr. Pharm. Des. 13, 1597-1605 (2007).
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 1597-1605
-
-
Wu, L.1
Ko, S.W.2
Zhuo, M.3
-
212
-
-
34248576759
-
Physiology and pathophysiology of purinergic neurotransmission
-
Burnstock G. Physiology and pathophysiology of purinergic neurotransmission. Physiol. Rev. 87, 659-797 (2007).
-
(2007)
Physiol. Rev.
, vol.87
, pp. 659-797
-
-
Burnstock, G.1
-
213
-
-
0033680583
-
P2 purinergic receptors: Modulation of cell function and therapeutic potential
-
Burnstock G, Williams M. P2 purinergic receptors: modulation of cell function and therapeutic potential. J. Pharmacol. Exp. 295 862-869 (2000).
-
(2000)
J. Pharmacol. Exp.
, vol.295
, pp. 862-869
-
-
Burnstock, G.1
Williams, M.2
-
214
-
-
0036788971
-
Molecular physiology of P2X receptors
-
North RA. Molecular physiology of P2X receptors. Physiol. Rev. 82, 1013-1067 (2002).
-
(2002)
Physiol. Rev.
, vol.82
, pp. 1013-1067
-
-
North, R.A.1
-
215
-
-
33746701380
-
P2X receptors as cell-surface ATP sensors in health and disease
-
Khakh BS, North RA. P2X receptors as cell-surface ATP sensors in health and disease. Nature 442 527-532 (2006).
-
(2006)
Nature
, vol.442
, pp. 527-532
-
-
Khakh, B.S.1
North, R.A.2
-
217
-
-
0035209620
-
International union of pharmacology. XXV. Nomenclature and classification of adenosine receptors
-
Fredholm BB, Ijzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol. Rev. 53, 527-552 (2001).
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 527-552
-
-
Fredholm, B.B.1
Ijzerman, A.P.2
Jacobson, K.A.3
Klotz, K.N.4
Linden, J.5
-
218
-
-
34250719722
-
Purine and pyrimidine receptors
-
Burnstock G. Purine and pyrimidine receptors. Cell. Mol. Life Sci. 64, 1471-1483 (2007).
-
(2007)
Cell. Mol. Life Sci.
, vol.64
, pp. 1471-1483
-
-
Burnstock, G.1
-
220
-
-
1842481005
-
Functional regulation of P2X6 receptors by N-linked glycosylation: Identification of novel α:β-methylene ATP-sensitive phenotype
-
Jones CA, Vial C, Sellers LA et al. Functional regulation of P2X6 receptors by N-linked glycosylation: identification of novel α:β-methylene ATP-sensitive phenotype. Mol. Pharmacol. 65 (4), 979-985 (2004).
-
(2004)
Mol. Pharmacol.
, vol.65
, Issue.4
, pp. 979-985
-
-
Jones, C.A.1
Vial, C.2
Sellers, L.A.3
-
221
-
-
0000563758
-
The capillary dilator substances in dry powders of spinal roots; a possible role for adenosine triphosphate in chemical transmission from nerve endings
-
Holton FA, Holton PJ. The capillary dilator substances in dry powders of spinal roots; a possible role for adenosine triphosphate in chemical transmission from nerve endings. J. Physiol. 126, 124-140 (1954).
-
(1954)
J. Physiol.
, vol.126
, pp. 124-140
-
-
Holton, F.A.1
Holton, P.J.2
-
222
-
-
0011731358
-
The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves
-
Holton PJ. The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves. J. Physiol. 145, 494-504 (1959).
-
(1959)
J. Physiol.
, vol.145
, pp. 494-504
-
-
Holton, P.J.1
-
223
-
-
0020565089
-
ATP excites a subpopulation of rat dorsal horn neurones
-
Jahr CE, Jessell TM. ATP excites a subpopulation of rat dorsal horn neurones. Nature 304, 730-733 (1983).
-
(1983)
Nature
, vol.304
, pp. 730-733
-
-
Jahr, C.E.1
Jessell, T.M.2
-
224
-
-
34250217010
-
Intrathecal administration of ATP produces long-lasting allodynia in rats: Differential mechanisms in the phase of the induction and maintenance
-
Nakagawa T, Wakamatsu K, Zhang N et al. Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance. Neuroscience 147, 445-455 (2007).
-
(2007)
Neuroscience
, vol.147
, pp. 445-455
-
-
Nakagawa, T.1
Wakamatsu, K.2
Zhang, N.3
-
225
-
-
0017682312
-
Observation on the algogenic actions of adenosine compounds on the human blister base preparation
-
Bleehen T, Keele CA. Observation on the algogenic actions of adenosine compounds on the human blister base preparation. Pain 3, 367-377 (1977).
-
(1977)
Pain
, vol.3
, pp. 367-377
-
-
Bleehen, T.1
Keele, C.A.2
-
226
-
-
0034063480
-
ATP in human skin elicits a dose-related pain response under conditions of hyperalgesia
-
Hamilton SG, Warburton J, Bhattacharjee A, Ward J, McMahon SB. ATP in human skin elicits a dose-related pain response under conditions of hyperalgesia. Brain 123, 1238-1246 (2000).
-
(2000)
Brain
, vol.123
, pp. 1238-1246
-
-
Hamilton, S.G.1
Warburton, J.2
Bhattacharjee, A.3
Ward, J.4
McMahon, S.B.5
-
227
-
-
0041328064
-
Contributions of P2X3 homomeric and heteromeric channels to acute and chronic pain
-
Jarvis MF. Contributions of P2X3 homomeric and heteromeric channels to acute and chronic pain. Exp. Opin. Ther. Targets 7, 513-522 (2003).
-
(2003)
Exp. Opin. Ther. Targets
, vol.7
, pp. 513-522
-
-
Jarvis, M.F.1
-
228
-
-
28444486336
-
The function of microglia through purinergic receptors: Neuropathic pain and cytokine release
-
Inoue K. The function of microglia through purinergic receptors: neuropathic pain and cytokine release. Pharmacol. Ther. 109, 210-226 (2006).
-
(2006)
Pharmacol. Ther.
, vol.109
, pp. 210-226
-
-
Inoue, K.1
-
229
-
-
38749115790
-
Painful purinergic receptors
-
Comprehensive and very useful review on the role of P2X receptors in pain
-
Donnelly-Roberts D, McGaraughty S, Shieh CC, Honore P, Jarvis MF. Painful purinergic receptors. J. Pharmaol. Exp. Ther. 324, 409-415 (2008). Comprehensive and very useful review on the role of P2X receptors in pain.
-
(2008)
J. Pharmaol. Exp. Ther.
, vol.324
, pp. 409-415
-
-
Donnelly-Roberts, D.1
McGaraughty, S.2
Shieh, C.C.3
Honore, P.4
Jarvis, M.F.5
-
230
-
-
60849085164
-
Positive allosteric modulatory effects of ajulemic acid at strychnine-sensitive glycine a1- and α1β-receptors
-
Ahrens J, Leuwer M, Reyhan D et al. Positive allosteric modulatory effects of ajulemic acid at strychnine-sensitive glycine a1- and α1β-receptors. Naunyn Schmied. Arch. Pharmacol. 379 (4), 371-378 (2009).
-
(2009)
Naunyn Schmied. Arch. Pharmacol.
, vol.379
, Issue.4
, pp. 371-378
-
-
Ahrens, J.1
Leuwer, M.2
Reyhan, D.3
-
231
-
-
0035313093
-
Purine-mediated signalling in pain and visceral perception
-
Burnstock G. Purine-mediated signalling in pain and visceral perception. Trends Pharmacol. Sci. 22, 182-188 (2001).
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 182-188
-
-
Burnstock, G.1
-
232
-
-
34250817635
-
P2X3 receptor mediates heat hyperalgesia in a rat model of trigeminal neuropathic pain
-
Shinoda M, Kawashima K, Ozaki N, Asai H, Nagamine K, Sugiura Y. P2X3 receptor mediates heat hyperalgesia in a rat model of trigeminal neuropathic pain. J. Pain 8, 588-597 (2007).
-
(2007)
J. Pain
, vol.8
, pp. 588-597
-
-
Shinoda, M.1
Kawashima, K.2
Ozaki, N.3
Asai, H.4
Nagamine, K.5
Sugiura, Y.6
-
233
-
-
0034718839
-
Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice
-
Cockayne DA, Hamilton SG, Zhu QM et al. Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice. Nature 407, 1011-1015 (2000).
-
(2000)
Nature
, vol.407
, pp. 1011-1015
-
-
Cockayne, D.A.1
Hamilton, S.G.2
Zhu, Q.M.3
-
234
-
-
0034718892
-
Warmcoding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors
-
Souslova V, Cesare P, Ding Y et al. Warmcoding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. Nature 407, 1015-1017 (2000).
-
(2000)
Nature
, vol.407
, pp. 1015-1017
-
-
Souslova, V.1
Cesare, P.2
Ding, Y.3
-
235
-
-
0036711339
-
3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
-
3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats. Pain 99, 11-19 (2002).
-
(2002)
Pain
, vol.99
, pp. 11-19
-
-
Honore, P.1
Kage, K.2
Mikusa, J.3
-
237
-
-
0036214576
-
TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: Comparison with reference analgesics
-
Honore P, Mikusa J, Bianchi B et al. TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics. Pain 96, 99-105 (2002).
-
(2002)
Pain
, vol.96
, pp. 99-105
-
-
Honore, P.1
Mikusa, J.2
Bianchi, B.3
-
238
-
-
0037421490
-
Changes in the gene expression of six subtypes of P2X receptors in rat dorsal root ganglion after spinal nerve ligation
-
Kim C, Chung JM, Chung K. Changes in the gene expression of six subtypes of P2X receptors in rat dorsal root ganglion after spinal nerve ligation. Neurosci. Lett. 337, 81-84 (2003).
-
(2003)
Neurosci. Lett.
, vol.337
, pp. 81-84
-
-
Kim, C.1
Chung, J.M.2
Chung, K.3
-
239
-
-
28444486336
-
The function of microglia through purinergic receptors: Neuropathic pain and cytokine release
-
Inoue K. The function of microglia through purinergic receptors: neuropathic pain and cytokine release. Pharmacol. Ther. 109, 210-226 (2006).
-
(2006)
Pharmacol. Ther.
, vol.109
, pp. 210-226
-
-
Inoue, K.1
-
241
-
-
0028303241
-
Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes
-
Nuttle LC, Dubyak GR. Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes. J. Biol. Chem. 269 (19), 13988-13996 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.19
, pp. 13988-13996
-
-
Nuttle, L.C.1
Dubyak, G.R.2
-
242
-
-
0033836116
-
Extracellular ATP triggers tumor necrosis factor-α release from rat microglia
-
Hide I, Tanaka M, Inoue A et al. Extracellular ATP triggers tumor necrosis factor-α release from rat microglia. J. Neurochem. 75, 965-972 (2000).
-
(2000)
J. Neurochem.
, vol.75
, pp. 965-972
-
-
Hide, I.1
Tanaka, M.2
Inoue, A.3
-
243
-
-
0034192082
-
Kinetics and mechanism of ATP-dependent IL-1 β release from microglial cells
-
Sanz JM, Di Virgilio F. Kinetics and mechanism of ATP-dependent IL-1 β release from microglial cells. J. Immunol. 164, 4893-4898 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 4893-4898
-
-
Sanz, J.M.1
Di Virgilio, F.2
-
244
-
-
0035426434
-
Glial activation: A driving force for pathological pain
-
Watkins LR, Milligan ED, Maier SF. Glial activation: a driving force for pathological pain. Trends Neurosci. 24: 450-455 (2001).
-
(2001)
Trends Neurosci.
, vol.24
, pp. 450-455
-
-
Watkins, L.R.1
Milligan, E.D.2
Maier, S.F.3
-
246
-
-
20144375454
-
Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
-
Chessell IP, Hatcher JP, Bountra C et al. Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain. Pain 114: 386-396 (2005).
-
(2005)
Pain
, vol.114
, pp. 386-396
-
-
Chessell, I.P.1
Hatcher, J.P.2
Bountra, C.3
-
248
-
-
34547101720
-
Acid-sensing ion channels in sensory perception
-
Lingueglia E. Acid-sensing ion channels in sensory perception. J. Biol. Chem. 282 (24), 17325-17329 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.24
, pp. 17325-17329
-
-
Lingueglia, E.1
-
249
-
-
67949092829
-
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
-
Gonzales EB, Kawate T, Gouaux E. Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. Nature 460, 599-605 (2009).
-
(2009)
Nature
, vol.460
, pp. 599-605
-
-
Gonzales, E.B.1
Kawate, T.2
Gouaux, E.3
-
250
-
-
62649157764
-
Modulation of glycine receptor function by the synthetic cannabinoid HU210
-
Reyhan D, Leuwer M, de la Roche J et al. Modulation of glycine receptor function by the synthetic cannabinoid HU210. Pharmacology 83 (5), 270-274 (2009).
-
(2009)
Pharmacology
, vol.83
, Issue.5
, pp. 270-274
-
-
Reyhan, D.1
Leuwer, M.2
De La Roche, J.3
-
251
-
-
70349916098
-
Acid sensor ion channels and receptors
-
Holzer P. Acid sensor ion channels and receptors. Handb. Exp. Pharmacol. 194, 283-332 (2009).
-
(2009)
Handb. Exp. Pharmacol.
, vol.194
, pp. 283-332
-
-
Holzer, P.1
-
252
-
-
0001684791
-
Pain: A chemical explanation
-
Lindahl O. Pain: a chemical explanation. Acta Rheumatol. Scand. 8, 161-169 (1962).
-
(1962)
Acta Rheumatol. Scand.
, vol.8
, pp. 161-169
-
-
Lindahl, O.1
-
253
-
-
0030459627
-
Tissue acidosis in nociception and pain
-
Reeh PW, Steen KH. Tissue acidosis in nociception and pain. Prog. Brain Res. 113, 143-151 (1996).
-
(1996)
Prog. Brain Res.
, vol.113
, pp. 143-151
-
-
Reeh, P.W.1
Steen, K.H.2
-
254
-
-
0035887733
-
Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation induced expression of acid-sensing ion channels in nociceptors
-
Voilley N, De Weille J, Mamet J, Lazdunski M. Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation induced expression of acid-sensing ion channels in nociceptors. J. Neurosci. 21 (20), 8026-8033 (2001).
-
(2001)
J. Neurosci.
, vol.21
, Issue.20
, pp. 8026-8033
-
-
Voilley, N.1
De Weille, J.2
Mamet, J.3
Lazdunski, M.4
-
255
-
-
0037115054
-
Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels
-
Mamet J, Baron A, Lazdunsky M, Voilley N. Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels. J. Neurosci. 22 (24), 10662-10670 (2002).
-
(2002)
J. Neurosci.
, vol.22
, Issue.24
, pp. 10662-10670
-
-
Mamet, J.1
Baron, A.2
Lazdunsky, M.3
Voilley, N.4
-
256
-
-
0033618608
-
Antinociception produced by systemic, spinal and supraspinal administration of amiloride in mice
-
Ferreira J, Santos AR, Calixto JB. Antinociception produced by systemic, spinal and supraspinal administration of amiloride in mice. Life Sci. 65 (10), 1059-1066 (1999).
-
(1999)
Life Sci.
, vol.65
, Issue.10
, pp. 1059-1066
-
-
Ferreira, J.1
Santos, A.R.2
Calixto, J.B.3
-
257
-
-
61349143029
-
Calcium-permeable acid-sensing ion channel in nociceptive plasticity: A new target for pain control
-
Xu TL, Duan B. Calcium-permeable acid-sensing ion channel in nociceptive plasticity: a new target for pain control. Prog. Neurobiol. 87, 171-180 (2009).
-
(2009)
Prog. Neurobiol.
, vol.87
, pp. 171-180
-
-
Xu, T.L.1
Duan, B.2
-
258
-
-
33748893261
-
Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury
-
Poirot O, Berta T, Decosterd I, Kellenberger S. Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury. J. Physiol. 576 (1), 215-234 (2006).
-
(2006)
J. Physiol.
, vol.576
, Issue.1
, pp. 215-234
-
-
Poirot, O.1
Berta, T.2
Decosterd, I.3
Kellenberger, S.4
-
259
-
-
34547502749
-
A tarantula peptide against pain via ASIC1a channels and opioid mechanisms
-
Recent key work outlining the proof of concept of the usefulness of acid-sensing ion channel 1a blockers in the treatment of neuropathic pain
-
Mazzuca M., Heurteaux C, Alloui A et al. A tarantula peptide against pain via ASIC1a channels and opioid mechanisms. Nat. Neurosci. 10 (8), 943-945 (2007). Recent key work outlining the proof of concept of the usefulness of acid-sensing ion channel 1a blockers in the treatment of neuropathic pain.
-
(2007)
Nat. Neurosci.
, vol.10
, Issue.8
, pp. 943-945
-
-
Mazzuca, M.1
Heurteaux, C.2
Alloui, A.3
-
261
-
-
33846158169
-
The role of GABA in the mediation and perception of pain
-
Enna SJ, McCarson KE. The role of GABA in the mediation and perception of pain. Adv. Pharmacol. 54, 1-27 (2006).
-
(2006)
Adv. Pharmacol.
, vol.54
, pp. 1-27
-
-
Enna, S.J.1
McCarson, K.E.2
-
262
-
-
33846245154
-
A receptor subtypes
-
A receptor subtypes. Adv. Pharmacol. 54, 231-263 (2006).
-
(2006)
Adv. Pharmacol.
, vol.54
, pp. 231-263
-
-
Sieghart, W.1
-
263
-
-
0032788376
-
A receptors: Evidence for peripheral primary afferent depolarization
-
A receptors: evidence for peripheral primary afferent depolarization. Neuroscience 93 (2), 713-722 (1999).
-
(1999)
Neuroscience
, vol.93
, Issue.2
, pp. 713-722
-
-
Carlton, S.M.1
Zhou, S.2
Coggeshall, R.E.3
-
265
-
-
0013851199
-
Pain mechanism: A new theory
-
Melzack R, Wall P. D. Pain mechanism: a new theory. Science 150, 971-979 (1965).
-
(1965)
Science
, vol.150
, pp. 971-979
-
-
Melzack, R.1
Wall, P.D.2
-
266
-
-
0030877482
-
Role of spinal γ-aminobutyric acid A receptors in formalininduced nociception in the rat
-
Kaneko M, Hammond DL. Role of spinal γ-aminobutyric acid A receptors in formalininduced nociception in the rat. J. Pharmacol. Exp Ther. 282 (2), 928-938 (1997).
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.282
, Issue.2
, pp. 928-938
-
-
Kaneko, M.1
Hammond, D.L.2
-
267
-
-
0036237512
-
B receptor pharmacology in a rat model of neuropathic pain
-
B receptor pharmacology in a rat model of neuropathic pain. Anesthesiology 96, 1161-1167 (2002).
-
(2002)
Anesthesiology
, vol.96
, pp. 1161-1167
-
-
Malan, T.P.1
Mata, H.P.2
Porreca, F.3
-
269
-
-
45849100495
-
A receptor modulation in dorsal root ganglia in vivo affects chronic pain after nerve injury
-
A receptor modulation in dorsal root ganglia in vivo affects chronic pain after nerve injury. Neuroscience 154, 1539-1553 (2008).
-
(2008)
Neuroscience
, vol.154
, pp. 1539-1553
-
-
Naik, A.K.1
Pathirathna, S.2
Jevtovic-Todorovic, V.3
-
270
-
-
0030966704
-
The effect of spinal GABA receptor agonist on tactile allodynia in a surgically-induced neuropathic pain model in the rat
-
Hwang JH, Yaksh TL. The effect of spinal GABA receptor agonist on tactile allodynia in a surgically-induced neuropathic pain model in the rat. Pain 70 (1), 15-22 (1997).
-
(1997)
Pain
, vol.70
, Issue.1
, pp. 15-22
-
-
Hwang, J.H.1
Yaksh, T.L.2
-
271
-
-
0035125663
-
Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: An isobolographic analysis
-
Loomis CW, Khandwala H, Osmond G, Hefferan MP. Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: an isobolographic analysis. J. Pharmacol. Exp. Ther. 296 (3), 756-761 (2001).
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, Issue.3
, pp. 756-761
-
-
Loomis, C.W.1
Khandwala, H.2
Osmond, G.3
Hefferan, M.P.4
-
272
-
-
0037485919
-
Selective loss of spinal GABAergic or glycinergic neurons is not necessary for development of thermal hyperalgesia in the chronic constriction injury model of neuropathic pain
-
Polgar E, Hughes DI, Riddel JS, Maxwell DJ, Puskar Z, Todd AJ. Selective loss of spinal GABAergic or glycinergic neurons is not necessary for development of thermal hyperalgesia in the chronic constriction injury model of neuropathic pain. Pain 104 (1-2), 229-239 (2003).
-
(2003)
Pain
, vol.104
, Issue.1-2
, pp. 229-239
-
-
Polgar, E.1
Hughes, D.I.2
Riddel, J.S.3
Maxwell, D.J.4
Puskar, Z.5
Todd, A.J.6
-
273
-
-
2442432825
-
Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn
-
Drew GM, Siddal PJ, Duggan AW. Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn. Pain 109, 379-388 (2004).
-
(2004)
Pain
, vol.109
, pp. 379-388
-
-
Drew, G.M.1
Siddal, P.J.2
Duggan, A.W.3
-
274
-
-
0030580562
-
Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts
-
Ibuki T, Hama AT, Wang XT, Pappas GD, Sagen J. Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts. Neuroscience 76, 845-858 (1997).
-
(1997)
Neuroscience
, vol.76
, pp. 845-858
-
-
Ibuki, T.1
Hama, A.T.2
Wang, X.T.3
Pappas, G.D.4
Sagen, J.5
-
275
-
-
0141626767
-
Muscimol prevents long-lasting potentiation of dorsal horn feld potential in rats with chronic constriction injury exhibiting decreased levels of the GABA transporter GAT-1
-
Miletic G, Draganic P, Pankratz MT, Miletic V. Muscimol prevents long-lasting potentiation of dorsal horn feld potential in rats with chronic constriction injury exhibiting decreased levels of the GABA transporter GAT-1. Pain 105, 347-353 (2003).
-
(2003)
Pain
, vol.105
, pp. 347-353
-
-
Miletic, G.1
Draganic, P.2
Pankratz, M.T.3
Miletic, V.4
-
276
-
-
0037223202
-
Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats
-
Obata K, Yamanaka H, Fukuoka T et al. Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats. Pain 101, 65-77 (2003).
-
(2003)
Pain
, vol.101
, pp. 65-77
-
-
Obata, K.1
Yamanaka, H.2
Fukuoka, T.3
-
277
-
-
1342344806
-
A receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics
-
A receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics. Annu. Rev. Pharmacol. Toxicol. 44, 475-498 (2004).
-
(2004)
Annu. Rev. Pharmacol. Toxicol.
, vol.44
, pp. 475-498
-
-
Rudolph, U.1
Mohler, H.2
-
279
-
-
0033592682
-
Benzodiazepine actions mediated by specific gamma-aminobutyric acid (A) receptor subtypes
-
Rudolph U, Crestani F, Benke D et al. Benzodiazepine actions mediated by specific gamma-aminobutyric acid (A) receptor subtypes. Nature 401 (6755), 796-800 (1999).
-
(1999)
Nature
, vol.401
, Issue.6755
, pp. 796-800
-
-
Rudolph, U.1
Crestani, F.2
Benke, D.3
-
281
-
-
57349185677
-
A receptor positive allosteric modulator: In vitro actions, pharmacokinetic properties and in vivo anxiolytic efficacy
-
A receptor positive allosteric modulator: in vitro actions, pharmacokinetic properties and in vivo anxiolytic efficacy. J. Pharmacol. Exp. Ther. 327 (3), 954-968 (2008).
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.327
, Issue.3
, pp. 954-968
-
-
Mirza, N.R.1
Larsen, J.S.2
Mathiasen, C.3
-
282
-
-
57349087154
-
A receptor-positive allosteric modulator NS11394 [3'-[5- (1-hydroxy-1-methyl- ethil) -benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil and gaboxadol in rat models of inflammatory and neuropathic pain
-
A receptor-positive allosteric modulator NS11394 [3'-[5- (1-hydroxy-1-methyl-ethil) -benzoimidazol-1-yl]-biphenyl-2- carbonitrile] with diazepam, zolpidem, bretazenil and gaboxadol in rat models of inflammatory and neuropathic pain. J. Pharmacol. Exp. Ther. 327, 969-981 (2008).
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.327
, pp. 969-981
-
-
Munro, G.1
Lopez-Garcia, J.A.2
Rivera-Arconada, I.3
-
284
-
-
67849094724
-
GABAergic analgesia: New insights from mutant mice and subtype-selective agonists
-
Zeilhofer HU, Mohler H, Di Lio A. GABAergic analgesia: new insights from mutant mice and subtype-selective agonists. Trends Pharmacol. Sci. 30 (8), 397-402 (2009).
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, Issue.8
, pp. 397-402
-
-
Zeilhofer, H.U.1
Mohler, H.2
Di Lio, A.3
-
286
-
-
58049120621
-
Native glycine receptor subtypes and their physiological role
-
Lynch JW. Native glycine receptor subtypes and their physiological role. Neuropharmacol. 56, 303-309 (2009).
-
(2009)
Neuropharmacol.
, vol.56
, pp. 303-309
-
-
Lynch, J.W.1
-
287
-
-
4644265039
-
Molecular structure and function of the glycine receptor chloride channel
-
Lynch JW. Molecular structure and function of the glycine receptor chloride channel. Physiol. Rev. 84, 1051-1095 (2004).
-
(2004)
Physiol. Rev.
, vol.84
, pp. 1051-1095
-
-
Lynch, J.W.1
-
288
-
-
34548205436
-
Molecular pharmacology of the glycine receptor chloride channels
-
Webb TI, Lynch JW. Molecular pharmacology of the glycine receptor chloride channels. Curr. Pharm Des. 13, 2350-2367 (2007).
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 2350-2367
-
-
Webb, T.I.1
Lynch, J.W.2
-
289
-
-
30944455443
-
Glycine receptors: A new therapeutic target in pain pathways
-
Lynch JW, Callister RJ. Glycine receptors: a new therapeutic target in pain pathways. Curr. Opin. Investig. Drugs. 7 (1):48-53 (2006).
-
(2006)
Curr. Opin. Investig. Drugs
, vol.7
, Issue.1
, pp. 48-53
-
-
Lynch, J.W.1
Callister, R.J.2
-
290
-
-
2442417968
-
GlyR α3: An essential target for spinal PGE2-mediated inflammatory pain sensitization
-
Harvey RJ, Depner UB, Wassle H et al. GlyR α3: an essential target for spinal PGE2-mediated inflammatory pain sensitization. Science 304 (5672), 884-887 (2004).
-
(2004)
Science
, vol.304
, Issue.5672
, pp. 884-887
-
-
Harvey, R.J.1
Depner, U.B.2
Wassle, H.3
-
291
-
-
0036139423
-
PGE (2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons
-
Ahmadi S, Lippross S, Neuhuber WL, Zeilhofer HU. PGE (2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons. Nat. Neurosci. 5 (1), 34-40 (2002).
-
(2002)
Nat. Neurosci.
, vol.5
, Issue.1
, pp. 34-40
-
-
Ahmadi, S.1
Lippross, S.2
Neuhuber, W.L.3
Zeilhofer, H.U.4
-
292
-
-
28844444625
-
Visceral, inflammatory and neuropathic pain in glycine receptor α 3-deficient mice
-
Racz I, Schutz B, Abo-Salem OM, Zimmer A. Visceral, inflammatory and neuropathic pain in glycine receptor α 3-deficient mice. Neuroreport 16 (18), 2025-2028 (2005).
-
(2005)
Neuroreport
, vol.16
, Issue.18
, pp. 2025-2028
-
-
Racz, I.1
Schutz, B.2
Abo-Salem, O.M.3
Zimmer, A.4
-
293
-
-
24744450794
-
The glycinergic control of spinal pain processing
-
Zeilhofer HU. The glycinergic control of spinal pain processing. Cell. Mol. Life Sci. 62, 1-9 (2005).
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 1-9
-
-
Zeilhofer, H.U.1
-
294
-
-
33847607450
-
Taurine in the anterior cingulated cortex diminishes neuropathic nociception: A possible interaction with the glycine A receptor
-
Pellicer F. Lopez-Avila A. Coffeen U. Ortega-Legaspi JM, Del Angel R. Taurine in the anterior cingulated cortex diminishes neuropathic nociception: a possible interaction with the glycine A receptor. Pain 11, 444-451 (2007).
-
(2007)
Pain
, vol.11
, pp. 444-451
-
-
Pellicer, F.1
Lopez-Avila, A.2
Coffeen, U.3
Ortega-Legaspi, J.M.4
Angel, R.D.5
-
295
-
-
59549106886
-
The nonpsychotropic cannabinoid cannabidiol modelates and directly activates a-1 and α-1-β glycine receptor function
-
Ahrens J, Reyhan D, Leuwer M et al. The nonpsychotropic cannabinoid cannabidiol modelates and directly activates a-1 and α-1-β glycine receptor function. Pharmacology 83 (4), 217-222 (2009).
-
(2009)
Pharmacology
, vol.83
, Issue.4
, pp. 217-222
-
-
Ahrens, J.1
Reyhan, D.2
Leuwer, M.3
-
296
-
-
65749098418
-
Antinociceptive effects of systemic lidocaine: Involvement of the spinal glycinergic system
-
Muth-Sebach U, Hermanns H, Stegmann JU et al. Antinociceptive effects of systemic lidocaine: involvement of the spinal glycinergic system. Eur. J. Pharmacol. 613 (1-3), 68-73 (2009).
-
(2009)
Eur. J. Pharmacol.
, vol.613
, Issue.1-3
, pp. 68-73
-
-
Muth-Sebach, U.1
Hermanns, H.2
Stegmann, J.U.3
-
297
-
-
77953397792
-
Discovery of novel positive allosteric modulators for the inhibitor glycine receptor
-
Presented at:, 729.3, Washingon, DC, USA, 15-19 November
-
Dekermendjian K, Wenna N, Aneiros E, Bernström J, Nyman E. Discovery of novel positive allosteric modulators for the inhibitor glycine receptor. Presented at: 38th Annual Meeting for the Society for Neuroscience 729.3, Washingon, DC, USA, 15-19 November 2008.
-
(2008)
38th Annual Meeting for the Society for Neuroscience
-
-
Dekermendjian, K.1
Wenna, N.2
Aneiros, E.3
Bernström, J.4
Nyman, E.5
-
298
-
-
0024474475
-
5-HT3 receptors are membrane ion channels
-
Derbach V, Surprenant A, North RA. 5-HT3 receptors are membrane ion channels. Nature 339, 706-709 (1989).
-
(1989)
Nature
, vol.339
, pp. 706-709
-
-
Derbach, V.1
Surprenant, A.2
North, R.A.3
-
299
-
-
0028183017
-
International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin)
-
Hoyer D, Clarke DE, Fozard JR et al. International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev. 46, 157-203 (1994).
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 157-203
-
-
Hoyer, D.1
Clarke, D.E.2
Fozard, J.R.3
-
301
-
-
58049215463
-
The 5-HT3 receptor - The relationship between structure and function
-
Barnes NM, Hales TG, Lummis S, Peters JA. The 5-HT3 receptor - the relationship between structure and function. Neuropharmacol. 56, 273-284 (2009).
-
(2009)
Neuropharmacol.
, vol.56
, pp. 273-284
-
-
Barnes, N.M.1
Hales, T.G.2
Lummis, S.3
Peters, J.A.4
-
302
-
-
0036458391
-
Differential subcellular localization of the 5-HT3-A receptor subunit in the rat central nervous system
-
Miquel MC, Emerit MB, Nosjean A et al. Differential subcellular localization of the 5-HT3-A receptor subunit in the rat central nervous system. Eur. J. Neurosci. 15, 449-457 (2002).
-
(2002)
Eur. J. Neurosci.
, vol.15
, pp. 449-457
-
-
Miquel, M.C.1
Emerit, M.B.2
Nosjean, A.3
-
303
-
-
0029656268
-
5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: A polymerase chain reaction study
-
Pierce PA, Xie GX, Levine JD, Peroutka SJ. 5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: a polymerase chain reaction study. Neuroscience 70, 553-559 (1996).
-
(1996)
Neuroscience
, vol.70
, pp. 553-559
-
-
Pierce, P.A.1
Xie, G.X.2
Levine, J.D.3
Peroutka, S.J.4
-
304
-
-
0021812342
-
Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs
-
Richardson BP, Engel G, Donatsch P, Stadler PA. Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs. Nature 316, 126-131 (1985).
-
(1985)
Nature
, vol.316
, pp. 126-131
-
-
Richardson, B.P.1
Engel, G.2
Donatsch, P.3
Stadler, P.A.4
-
305
-
-
0026534030
-
Receptor mediation of 5-HT-induced inflammation and nociception in rats
-
Sufka KJ, Schomburg FM, Giordano J. Receptor mediation of 5-HT-induced inflammation and nociception in rats. Pharmacol. Biochem. Behav. 41, 53-56 (1992).
-
(1992)
Pharmacol. Biochem. Behav.
, vol.41
, pp. 53-56
-
-
Sufka, K.J.1
Schomburg, F.M.2
Giordano, J.3
-
306
-
-
0036462488
-
The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors
-
Zeitz KP, Guy N, Malmberg AB et al. The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. J. Neurosci. 22, 1010-1019 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 1010-1019
-
-
Zeitz, K.P.1
Guy, N.2
Malmberg, A.B.3
-
307
-
-
0032579868
-
Antagonism of peripheral 5-HT4 receptors reduces visceral and cutaneous pain in mice, and induces visceral analgesia after simultaneous inactivation of 5-HT3 receptors
-
Espejo EF, Gil E. Antagonism of peripheral 5-HT4 receptors reduces visceral and cutaneous pain in mice, and induces visceral analgesia after simultaneous inactivation of 5-HT3 receptors. Brain Res. 788, 20-24 (1998).
-
(1998)
Brain Res.
, vol.788
, pp. 20-24
-
-
Espejo, E.F.1
Gil, E.2
-
308
-
-
0024593409
-
Differential analgesic actions of serotonin 5-HT3 receptor antagonists in the mouse
-
Giordano J, Dyche J. Differential analgesic actions of serotonin 5-HT3 receptor antagonists in the mouse. Neuropharmacol. 28, 423-427 (1989).
-
(1989)
Neuropharmacol.
, vol.28
, pp. 423-427
-
-
Giordano, J.1
Dyche, J.2
-
309
-
-
0024426507
-
Peripherally administered serotonin 5-HT3 receptor antagonists reduce inflammatory pain in rats
-
Giordano J, Rogers LV. Peripherally administered serotonin 5-HT3 receptor antagonists reduce inflammatory pain in rats. Eur. J. Pharmacol. 170, 83-86 (1989).
-
(1989)
Eur. J. Pharmacol.
, vol.170
, pp. 83-86
-
-
Giordano, J.1
Rogers, L.V.2
-
310
-
-
0024541049
-
Influence of a specific 5-HT3 antagonist on carrageenan-induced hyperalgesia in rats
-
Eschalier A, Kayser V, Guilbaud G. Influence of a specific 5-HT3 antagonist on carrageenan-induced hyperalgesia in rats. Pain 36, 249-255 (1989).
-
(1989)
Pain
, vol.36
, pp. 249-255
-
-
Eschalier, A.1
Kayser, V.2
Guilbaud, G.3
-
311
-
-
62849093451
-
3 receptor for days causes sustained relief from mechanical allodynia following spinal cord injury
-
3 receptor for days causes sustained relief from mechanical allodynia following spinal cord injury. J. Neurosci. Res. 87, 418-424 (2009).
-
(2009)
J. Neurosci. Res.
, vol.87
, pp. 418-424
-
-
Chen, Y.1
Oatway, M.A.2
Weaver, L.C.3
-
312
-
-
0021744910
-
Neuronal 5-HT receptors in the periphery
-
Fozard JR. Neuronal 5-HT receptors in the periphery. Neuropharmacol. 23, 1473-1486 (1984).
-
(1984)
Neuropharmacol.
, vol.23
, pp. 1473-1486
-
-
Fozard, J.R.1
-
313
-
-
0031664093
-
Topical ondansetron attenuates nociceptive and inflammatory effects of intradermal capsaicin in humans
-
Giordano J, Daleo C, Sacks SM. Topical ondansetron attenuates nociceptive and inflammatory effects of intradermal capsaicin in humans. Eur. J. Pharmacol. 354, R13-14 (1998).
-
(1998)
Eur. J. Pharmacol.
, vol.354
-
-
Giordano, J.1
Daleo, C.2
Sacks, S.M.3
-
314
-
-
0142150238
-
3 receptor antagonist ondansetron have an analgesic effect in neuropathic pain? A double-blinded, placebo-controlled cross-over study
-
3 receptor antagonist ondansetron have an analgesic effect in neuropathic pain? A double-blinded, placebo-controlled cross-over study. Anesth. Analg. 97, 1474-1478 (2003).
-
(2003)
Anesth. Analg.
, vol.97
, pp. 1474-1478
-
-
McCleane, G.J.1
Suzuki, R.2
Dickenson, A.H.3
-
315
-
-
0342547245
-
Ondansetron exhibits the properties of a local anesthetic
-
Ye JH, Mui WC, Ren J et al. Ondansetron exhibits the properties of a local anesthetic. Anesth. Analg. 85, 1116-1121 (1997).
-
(1997)
Anesth. Analg.
, vol.85
, pp. 1116-1121
-
-
Ye, J.H.1
Mui, W.C.2
Ren, J.3
-
316
-
-
0033050601
-
Ondansetron pretreatment to alleviate pain on propofol injection: A randomized, controlled, double-blinded study
-
Ambesh SP, Dubey PK, Sinha PK. Ondansetron pretreatment to alleviate pain on propofol injection: a randomized, controlled, double-blinded study. Anesth. Analg. 98, 197-199 (1999).
-
(1999)
Anesth. Analg.
, vol.98
, pp. 197-199
-
-
Ambesh, S.P.1
Dubey, P.K.2
Sinha, P.K.3
-
319
-
-
11844276603
-
Neuronal nicotinic receptors: From structure to pathology
-
Gotti C, Clementi F. Neuronal nicotinic receptors: from structure to pathology. Prog. Neurobiol. 74 (6), 363-396 (2004).
-
(2004)
Prog. Neurobiol.
, vol.74
, Issue.6
, pp. 363-396
-
-
Gotti, C.1
Clementi, F.2
-
321
-
-
0033135906
-
Single channel properties of human α3 AChRs: Impact of β2, β4 and α5 subunits
-
Nelson ME, Lindstrom J. Single channel properties of human α3 AChRs: impact of β2, β4 and α5 subunits. J. Physiol. 516 (3), 657-678 (1999).
-
(1999)
J. Physiol.
, vol.516
, Issue.3
, pp. 657-678
-
-
Nelson, M.E.1
Lindstrom, J.2
-
322
-
-
3543104904
-
Nicotinic acetylcholine receptor subtypes in nociceptive dorsal root ganglion neurons of the adult rat
-
Haberberger RV, Bernardini N, Kress M, Hartmann P, Lips KS, Kummer W. Nicotinic acetylcholine receptor subtypes in nociceptive dorsal root ganglion neurons of the adult rat. Auton. Neurosci. 113, 32-42 (2004).
-
(2004)
Auton. Neurosci.
, vol.113
, pp. 32-42
-
-
Haberberger, R.V.1
Bernardini, N.2
Kress, M.3
Hartmann, P.4
Lips, K.S.5
Kummer, W.6
-
323
-
-
0242300269
-
Nicotinic acetylcholine receptors distribution in relation to spinal neurotransmission pathways
-
Khan I, Osaka H, Stanislaus S. Nicotinic acetylcholine receptors distribution in relation to spinal neurotransmission pathways. J. Comp. Neurol. 467 (1), 44-59 (2003).
-
(2003)
J. Comp. Neurol.
, vol.467
, Issue.1
, pp. 44-59
-
-
Khan, I.1
Osaka, H.2
Stanislaus, S.3
-
324
-
-
0022451017
-
The spinal cord as a major site for the antinociceptive action of nicotine in the rat
-
Aceto MD, Bagley RS, Dewey WL, Fu TC, Martin BR. The spinal cord as a major site for the antinociceptive action of nicotine in the rat. Neuropharmacol. 25, 1031-1036 (1986).
-
(1986)
Neuropharmacol.
, vol.25
, pp. 1031-1036
-
-
Aceto, M.D.1
Bagley, R.S.2
Dewey, W.L.3
Fu, T.C.4
Martin, B.R.5
-
325
-
-
0028230727
-
Epibatidine, a potent analgetic and nicotinic agonist
-
Badio B, Daly J W. Epibatidine, a potent analgetic and nicotinic agonist. Mol. Pharmacol. 45, 563-569 (1994).
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 563-569
-
-
Badio, B.1
Daly, J.W.2
-
326
-
-
0033614401
-
Reduced antinociception in mice lacking neuronal nicotinic receptor subunits
-
Marubio LM, Arroyo-Jimenez MM, Cordero-Erausquin M et al. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature 398, 805-810 (1999).
-
(1999)
Nature
, vol.398
, pp. 805-810
-
-
Marubio, L.M.1
Arroyo-Jimenez, M.M.2
Cordero-Erausquin, M.3
-
327
-
-
0034648041
-
Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat
-
Bitner RS, Nikkel AL, Curzon P et al. Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat. Brain Res. 871, 66-74 (2000).
-
(2000)
Brain Res.
, vol.871
, pp. 66-74
-
-
Bitner, R.S.1
Nikkel, A.L.2
Curzon, P.3
-
328
-
-
34248570453
-
Genetic approaches identify differential roles for α4b2 nicotinic receptors in acute models of antinociception in mice
-
Damaj MI, Fonck C, Marks MJ et al. Genetic approaches identify differential roles for α4b2 nicotinic receptors in acute models of antinociception in mice. J. Pharmacol. Exp. Ther. 321, 1161-1169 (2007).
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.321
, pp. 1161-1169
-
-
Damaj, M.I.1
Fonck, C.2
Marks, M.J.3
-
329
-
-
0030472265
-
Presynaptic nicotinic acetylcholine receptors in the brain
-
Wonnacott S, Soliakov L, Wilkie G, Redfern P, Marshall D. Presynaptic nicotinic acetylcholine receptors in the brain. Drug Dev. Res. 38, 149-159 (1996).
-
(1996)
Drug Dev. Res.
, vol.38
, pp. 149-159
-
-
Wonnacott, S.1
Soliakov, L.2
Wilkie, G.3
Redfern, P.4
Marshall, D.5
-
330
-
-
0037849869
-
Peripheral and central sites of action for A-85380 in the spinal nerve ligation model of neuropathic pain
-
Rueter LE, Kohlass KL, Curzon P, Surowy CS, Meyer MD. Peripheral and central sites of action for A-85380 in the spinal nerve ligation model of neuropathic pain. Pain 103 (3), 269-276 (2003).
-
(2003)
Pain
, vol.103
, Issue.3
, pp. 269-276
-
-
Rueter, L.E.1
Kohlass, K.L.2
Curzon, P.3
Surowy, C.S.4
Meyer, M.D.5
-
331
-
-
0034193948
-
Analgesic prolfile of the nicotinic acetylcholine receptor agonists, (+) -epibatidine and ABT-594 in models of persistent inflammatory and neuropathic pain
-
Kesingland AC, Gentry CT, Panesar MS et al. Analgesic prolfile of the nicotinic acetylcholine receptor agonists, (+) -epibatidine and ABT-594 in models of persistent inflammatory and neuropathic pain. Pain 86 (1-2), 113-118 (2000).
-
(2000)
Pain
, vol.86
, Issue.1-2
, pp. 113-118
-
-
Kesingland, A.C.1
Gentry, C.T.2
Panesar, M.S.3
-
332
-
-
0032504712
-
ABT-594, a novel cholinergic channel modulator, is efficacious in nerve ligation and diabetic neuropathy models of neuropathic pain
-
Bannon AW, Decker MW, Kim DJ, Campbell JE, Arneric SP. ABT-594, a novel cholinergic channel modulator, is efficacious in nerve ligation and diabetic neuropathy models of neuropathic pain. Brain Res. 801 (1-2), 158-163 (1998).
-
(1998)
Brain Res.
, vol.801
, Issue.1-2
, pp. 158-163
-
-
Bannon, A.W.1
Decker, M.W.2
Kim, D.J.3
Campbell, J.E.4
Arneric, S.P.5
-
333
-
-
77953404111
-
TC-6499: An orally effective and selective α-4-β-2 neuronal nicotinic receptor agonist with anti-allodynic activity
-
39.7, San Diego, CA, USA, 3-7 November
-
Jordan KG, Hauser TA, Fedorov N, Traina VM, Bencherif M. TC-6499: an orally effective and selective α-4-β-2 neuronal nicotinic receptor agonist with anti-allodynic activity. 37th Annual Meeting of the Society for Neuroscience abstr. 39.7, San Diego, CA, USA, 3-7 November 2007.
-
(2007)
37th Annual Meeting of the Society for Neuroscience Abstr
-
-
Jordan, K.G.1
Hauser, T.A.2
Fedorov, N.3
Traina, V.M.4
Bencherif, M.5
-
334
-
-
34548679635
-
Neuronal nicotinic receptors: A perspective on two decades of drug discovery research
-
Arneric SP, Holladay M, Williams M. Neuronal nicotinic receptors: a perspective on two decades of drug discovery research. Biochemical Pharmacol. 74, 1092-1101 (2007).
-
(2007)
Biochemical Pharmacol.
, vol.74
, pp. 1092-1101
-
-
Arneric, S.P.1
Holladay, M.2
Williams, M.3
-
335
-
-
69949159308
-
Nicotinic receptors: Allosteric transitions and therapeutic targets in the nervous system
-
Recent and interesting review on nicotinic receptors as drug targets in the nervous system
-
Taly A, Cirringer PJ, Guedin D, Lestage P, Changeux JP. Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat. Rev. Drug Discov. 8, 733-750 (2009). Recent and interesting review on nicotinic receptors as drug targets in the nervous system.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 733-750
-
-
Taly, A.1
Cirringer, P.J.2
Guedin, D.3
Lestage, P.4
Changeux, J.P.5
-
336
-
-
17744364985
-
Retigabine: Chemical synthesis to clinical application
-
Blackburn-Munro G, Dalby-Brown W, Mirza N R, Mikkelsen JD, Blackburn-Munro RE. Retigabine: chemical synthesis to clinical application. CNS Drug Rev. 11 (1), 1-20 (2005).
-
(2005)
CNS Drug Rev.
, vol.11
, Issue.1
, pp. 1-20
-
-
Blackburn-Munro, G.1
Dalby-Brown, W.2
Mirza, N.R.3
Mikkelsen, J.D.4
Blackburn-Munro, R.E.5
-
337
-
-
7244247251
-
Ralfinamide
-
Cattabeni F. Ralfinamide. IDrugs 7 (10), 935-939 (2004).
-
(2004)
IDrugs
, vol.7
, Issue.10
, pp. 935-939
-
-
Cattabeni, F.1
-
338
-
-
53049096894
-
Ralfinamide acts through NMDA receptor complex: A central role for chronic pain treatment
-
Colombo E, Curatolo L, Caccia C, Faravelli L et al. Ralfinamide acts through NMDA receptor complex: a central role for chronic pain treatment. Eur. J. Pain, 11 (1), 152-153 (2007).
-
(2007)
Eur. J. Pain
, vol.11
, Issue.1
, pp. 152-153
-
-
Colombo, E.1
Curatolo, L.2
Caccia, C.3
Faravelli, L.4
-
339
-
-
12444329963
-
Mechanisms of action of CHF3381 in the forebrain
-
Barbieri M, Bregola G, Buzzi A et al. Mechanisms of action of CHF3381 in the forebrain. Br. J. Pharmacol. 139, 1333-1341 (2003).
-
(2003)
Br. J. Pharmacol.
, vol.139
, pp. 1333-1341
-
-
Barbieri, M.1
Bregola, G.2
Buzzi, A.3
-
340
-
-
46049111268
-
Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy
-
Simpson DM, Brown SJ, Tobias J. Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy. Neurology, 70, 2305-2313 (2008).
-
(2008)
Neurology
, vol.70
, pp. 2305-2313
-
-
Simpson, D.M.1
Brown, S.J.2
Tobias, J.3
-
341
-
-
39649097645
-
An open-label pilot study of high-concentration capsaicin patch in painful HIV neuropathy
-
Simpson DM, Estanislao L, Brown SJ. An open-label pilot study of high-concentration capsaicin patch in painful HIV neuropathy. Pain Symptom. Manag. 35, 299-306 (2008).
-
(2008)
Pain Symptom. Manag.
, vol.35
, pp. 299-306
-
-
Simpson, D.M.1
Estanislao, L.2
Brown, S.J.3
-
342
-
-
33646677987
-
Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development
-
Rami HK, Thompson M, Stemp G et al. Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development. Bioorg. Med. Chem. Lett. 16 (12) 3287-3291 (2006).
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, Issue.12
, pp. 3287-3291
-
-
Rami, H.K.1
Thompson, M.2
Stemp, G.3
-
343
-
-
20144376596
-
Identification and biological evaluation of 4- (3-trifluoromethylpyridin- 2-yl) piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl) amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist
-
Swanson DM, Dubin AE, Shah C et al. Identification and biological evaluation of 4- (3-trifluoromethylpyridin-2-yl) piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl) amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist. J. Med. Chem. 48 (6), 1857-1872 (2005).
-
(2005)
J. Med. Chem.
, vol.48
, Issue.6
, pp. 1857-1872
-
-
Swanson, D.M.1
Dubin, A.E.2
Shah, C.3
-
344
-
-
0038128285
-
N- (4-tertiarybutylphenyl) -4- (3-cholorphyridin-2-yl) tetrahydropyrazine -1 (2H) -carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. In vivo vharacterization in rat models of inflammatory and neuropathic pain
-
Pomonis JD, Harrison JE, Mark L, Bristol DR, Valenzano KJ, Walker K. N- (4-tertiarybutylphenyl) -4- (3-cholorphyridin-2-yl) tetrahydropyrazine -1 (2H) -carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. In vivo vharacterization in rat models of inflammatory and neuropathic pain. J. Pharmacol. Exp. Ther. 306, 387-393 (2003).
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 387-393
-
-
Pomonis, J.D.1
Harrison, J.E.2
Mark, L.3
Bristol, D.R.4
Valenzano, K.J.5
Walker, K.6
-
345
-
-
31544449199
-
Identification and biological characterization of 6-aryl-7- isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain
-
Culshaw AJ, Bevan S, Christiansen M et al. Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain. J. Med. Chem. 49 (2), 471-474 (2006).
-
(2006)
J. Med. Chem.
, vol.49
, Issue.2
, pp. 471-474
-
-
Culshaw, A.J.1
Bevan, S.2
Christiansen, M.3
-
346
-
-
0028021842
-
The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin
-
Walpole C S J, Bevan S, Bovermann G et al. The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin. J. Med. Chem. 37 (13), 1942-1954 (1994).
-
(1994)
J. Med. Chem.
, vol.37
, Issue.13
, pp. 1942-1954
-
-
Walpole, C.S.J.1
Bevan, S.2
Bovermann, G.3
-
347
-
-
0037215646
-
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain
-
Walker KM, Urban L, Medhurst SJ et al. The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain. J. Pharm. Exp. Ther. 304, 56-62 (2003).
-
(2003)
J. Pharm. Exp. Ther.
, vol.304
, pp. 56-62
-
-
Walker, K.M.1
Urban, L.2
Medhurst, S.J.3
-
348
-
-
77950443755
-
A-967079, a potent and selective TRPA1 antagonist, is efficacious in rat preclinical pain models
-
Presented at:, Chicago, IL, USA, 17-21 October, Abstract 761.3
-
Gauvin DM, Mikusa J, Baker S et al. A-967079, a potent and selective TRPA1 antagonist, is efficacious in rat preclinical pain models. Presented at: 39th Annual Meeting of the Society for Neuroscience. Chicago, IL, USA, 17-21 October 2009 (Abstract 761.3).
-
(2009)
39th Annual Meeting of the Society for Neuroscience
-
-
Gauvin, D.M.1
Mikusa, J.2
Baker, S.3
-
349
-
-
77953423414
-
-
Presented at: 39th Annual Meeting of the Society for Neuroscience, Chicago, IL, USA, 17-21 October, Abstract 73.7
-
Watanabe S, Ohmi M, Inoue T, Nonomura C, Fujiiuchi A. Identification of novel TRPM8 channel antagonists. Presented at: 39th Annual Meeting of the Society for Neuroscience. Chicago, IL, USA, 17-21 October 2009 (Abstract 73.7).
-
(2009)
Identification of Novel TRPM8 Channel Antagonists
-
-
Watanabe, S.1
Ohmi, M.2
Inoue, T.3
Nonomura, C.4
Fujiiuchi, A.5
-
350
-
-
77953425135
-
Efficacy and safety of ralfinamide in a 8-week, randomised, double-blind, placebo controlled, international trial in patients with neuropathic pain. Ralfinamide 001 study group
-
Presented at:, 11-14 April, Abstract P03, 179
-
th Annual Meeting of the American Academy of Neurology. 11-14 April 2008 (Abstract P03, 179).
-
(2008)
th Annual Meeting of the American Academy of Neurology
-
-
Anand, R.1
Rossetti, S.M.2
Marchettini, P.3
-
351
-
-
53049102612
-
Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat
-
Zhang, S-H, Blech-Hermoni Y, Seltzer, Z, Faravelli L et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain 39 (2), 293-305 (2008).
-
(2008)
Pain
, vol.39
, Issue.2
, pp. 293-305
-
-
Zhang, S.-H.1
Blech-Hermoni, Y.2
Seltzer, Z.3
Faravelli, L.4
-
353
-
-
35348997034
-
+ channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats
-
+ channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats. Exper. Neurol. 208, 63-72 (2007).
-
(2007)
Exper. Neurol.
, vol.208
, pp. 63-72
-
-
Yamane, H.1
De Groat, W.C.2
Sculptoreanu, A.3
-
354
-
-
33644836275
-
Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats
-
Brochu RM, Dick IE, Tarpley JW et al. Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats. Mol. Pharmacol. 69 (3), 823-832 (2006).
-
(2006)
Mol. Pharmacol.
, vol.69
, Issue.3
, pp. 823-832
-
-
Brochu, R.M.1
Dick, I.E.2
Tarpley, J.W.3
-
355
-
-
20144383383
-
Novel cyclopentane dicarboxamide sodium channel blocker, as potential
-
Shao PP, Ok D, Fisher MH et al. Novel cyclopentane dicarboxamide sodium channel blocker, as potential treatment for chronic pain. Bioorg. Med. Che. Lett. 15 (7), 1901-1907 (2005).
-
(2005)
Bioorg. Med. Che. Lett.
, vol.15
, Issue.7
, pp. 1901-1907
-
-
Shao, P.P.1
Ok, D.2
Fisher, M.H.3
-
356
-
-
34347213786
-
v1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat
-
v1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc. Natl Acad. Sci. USA 104 (20), 8520-8525 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.20
, pp. 8520-8525
-
-
Jarvis, M.F.1
Honore, P.2
C-C, S.3
-
357
-
-
39149092391
-
v1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain
-
v1.8 selective compounds and evidence that channel subtype block is sufficient for efficacy in several rat pain models
-
v1.8 selective compounds and evidence that channel subtype block is sufficient for efficacy in several rat pain models.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 407-416
-
-
Kort, M.E.1
Drizin, I.2
Gregg, R.J.3
-
358
-
-
35148888599
-
v1.7 blockers: Potential treatments for neuropathic pain
-
v1.7 blockers can exhibit good potency in a rat model for neuropathic pain
-
v1.7 blockers can exhibit good potency in a rat model for neuropathic pain.
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, Issue.22
, pp. 6172-6177
-
-
Hoyt, S.B.1
London, C.2
Ok, D.3
-
360
-
-
70149105324
-
v1.7 sodium channel blocker reverses hyperalgesia and allodynia on rat models of inflammatory and neuropathic pain
-
v1.7 sodium channel blocker reverses hyperalgesia and allodynia on rat models of inflammatory and neuropathic pain. Anesth. Analg. 109, 951-958 (2009).
-
(2009)
Anesth. Analg.
, vol.109
, pp. 951-958
-
-
McGowan, E.1
Hoyt, S.B.2
Li, X.3
-
361
-
-
71049127913
-
Scaffold-based design and synthesis of potent N-type calcium channel blockers
-
Zamponi GW, Feng Z-P, Zhang L et al. Scaffold-based design and synthesis of potent N-type calcium channel blockers. Bioorg. Med. Chem. Lett. 19, 6467-6472 (2009).
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 6467-6472
-
-
Zamponi, G.W.1
Z-P, F.2
Zhang, L.3
-
362
-
-
33846377544
-
Synthesis and SAR of novel 2-arylthiazolidinones as selective analgesic N-type calcium channel blockers
-
Knutsen L J S, Hobbs CJ, Earnshaw CG et al. Synthesis and SAR of novel 2-arylthiazolidinones as selective analgesic N-type calcium channel blockers. Bioorg. Med. Chem. Lett. 17 (3), 662-667 (2007).
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, Issue.3
, pp. 662-667
-
-
Knutsen, L.J.S.1
Hobbs, C.J.2
Earnshaw, C.G.3
-
363
-
-
77953462206
-
The structure activity relationship study on the water-soluble 1, 4-dihydropyridine derivatives blocking N-type calcium channels
-
abstr. P150, 31 August
-
Yamamoto T, Niwa S, Ohno S et al. The structure activity relationship study on the water-soluble 1, 4-dihydropyridine derivatives blocking N-type calcium channels. 20th International Symposium on Medicinal Chemistry abstr. P150, 31 August 2008.
-
(2008)
20th International Symposium on Medicinal Chemistry
-
-
Yamamoto, T.1
Niwa, S.2
Ohno, S.3
-
364
-
-
77953471680
-
Spinal antinociceptive effects of a new calcium channel blocker, AGS1164
-
in rats, New Orleans, LA, 8-12 November
-
Saito Y, Kirihara Y, Hashimoto T et al. Spinal antinociceptive effects of a new calcium channel blocker, AGS1164, in rats. 33rd Annual Meeting of the Society for Neuroscience. New Orleans, LA, 8-12 November 2003.
-
(2003)
33rd Annual Meeting of the Society for Neuroscience
-
-
Saito, Y.1
Kirihara, Y.2
Hashimoto, T.3
-
365
-
-
77953463983
-
Analgesic effects of a novel compound which posseses N-type calcium channel blocking activity
-
656.2, Orlando, FL, 2-7 November
-
Koganei H, Fujita S, Iwayama S et al. Analgesic effects of a novel compound which posseses N-type calcium channel blocking activity. 32rd Annual Meeting of the Society for Neuroscience abs. 656.2, Orlando, FL, 2-7 November 2002.
-
(2002)
32rd Annual Meeting of the Society for Neuroscience Abs
-
-
Koganei, H.1
Fujita, S.2
Iwayama, S.3
-
366
-
-
54549099278
-
Discovery of 1, 4-substituted piperidines as potent and selective inhibitors of T-type calcium channels
-
Yang Z-Q, Barrow JC, Shipe WD et al. Discovery of 1, 4-substituted piperidines as potent and selective inhibitors of T-type calcium channels. J. Med. Chem. 51 (20), 6471-6477 (2009).
-
(2009)
J. Med. Chem.
, vol.51
, Issue.20
, pp. 6471-6477
-
-
Z-Q, Y.1
Barrow, J.C.2
Shipe, W.D.3
-
367
-
-
52949108838
-
Combination therapy with flupirtine and opioid: Open-label case series in the treatment of neuropathic pain associated with cancer
-
Goodchild CS, Nelson J, Cooke I, Ashby M, Jackson K. Combination therapy with flupirtine and opioid: open-label case series in the treatment of neuropathic pain associated with cancer. Pain Med. 9 (7), 939-949 (2008).
-
(2008)
Pain Med.
, vol.9
, Issue.7
, pp. 939-949
-
-
Goodchild, C.S.1
Nelson, J.2
Cooke, I.3
Ashby, M.4
Jackson, K.5
-
368
-
-
77953466029
-
ICA-27243: A novel, potent, and selective KCNQ2/Q3 potassium channel activator
-
Presented at:, Washington, DC, USA, 12-16 November, Abstract 153.13
-
Wickenden AD, McNaughton-Smith G, Roeloffs R, London B, Clark S. ICA-27243: a novel, potent, and selective KCNQ2/Q3 potassium channel activator. Presented at: 35th Annual Meeting of the Society for Neuroscience Washington, DC, USA, 12-16 November 2005 (Abstract 153.13).
-
(2005)
35th Annual Meeting of the Society for Neuroscience
-
-
Wickenden, A.D.1
McNaughton-Smith, G.2
Roeloffs, R.3
London, B.4
Clark, S.5
-
369
-
-
77953401030
-
In vivo profle of a KCNQ2/3 selective versus a pan-KCNQ activator in rodent models of pain
-
Presented at:, Washington, DC, USA 15-18 November, Abstract 631.4
-
Roeloffs R, Harrison W, Mahoney JH, Leach C, Robinette L. In vivo profle of a KCNQ2/3 selective versus a pan-KCNQ activator in rodent models of pain. Presented at: 38th Annual Meeting of the Society for Neuroscience Washington, DC, USA 15-18 November 2008 (Abstract 631.4).
-
(2008)
38th Annual Meeting of the Society for Neuroscience
-
-
Roeloffs, R.1
Harrison, W.2
Mahoney, J.H.3
Leach, C.4
Robinette, L.5
-
370
-
-
40849085408
-
N- (6-chloro-pyridin-3-yl) -3, 4-difluorobenzamide (ICA-27243): A novel, selective KCNQ2/Q3 potassium channel activator
-
Wickenden AD, Krajewski JL, London B et al. N- (6-chloro-pyridin-3-yl) -3, 4-difluorobenzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. Mol. Pharmacol. 73 (3), 977-986 (2008).
-
(2008)
Mol. Pharmacol.
, vol.73
, Issue.3
, pp. 977-986
-
-
Wickenden, A.D.1
Krajewski, J.L.2
London, B.3
-
371
-
-
2442700343
-
Synthesis and structure-activity relationship of acrylamides as KCNQ2 potassium channel openers
-
Wu YJ, He H, Sun L-Q et al. Synthesis and structure-activity relationship of acrylamides as KCNQ2 potassium channel openers. J. Med. Chem. 47 (11), 2887-2896 (2004).
-
(2004)
J. Med. Chem.
, vol.47
, Issue.11
, pp. 2887-2896
-
-
Wu, Y.J.1
He, H.2
L-Q, S.3
-
372
-
-
77953439644
-
v-β-1- subunit interactions are antianalgesic in vivo
-
Presented at:, Diego, CA, 3-7 November, Abstract 469.30
-
v-β-1-subunit interactions are antianalgesic in vivo. Presented at: 37th Annual Meeting of the Society for Neuroscience San Diego, CA, 3-7 November 2007 (Abstract 469.30).
-
(2007)
37th Annual Meeting of the Society for Neuroscience San
-
-
Boden, P.R.1
Gentry, C.2
Lhuller, L.3
Aziz, O.4
-
373
-
-
68449095673
-
The effects of PPC-5650, an ASIC1a antagonist on hyperalgesia in a human inflammatory pain model
-
Presented at:, 6-8 November
-
Mangat M, Schmudermaier M, Dubé GR, Schmudermaier B, Gervais F, Gustorff B. The effects of PPC-5650, an ASIC1a antagonist on hyperalgesia in a human inflammatory pain model. Presented at: The 11th International Conference on the Mechanisms and Treatment of Neuropathic Pain 6-8 November 2008.
-
(2008)
The 11th International Conference on the Mechanisms and Treatment of Neuropathic Pain
-
-
Mangat, M.1
Schmudermaier, M.2
Dubé, G.R.3
Schmudermaier, B.4
Gervais, F.5
Gustorff, B.6
-
374
-
-
76649091819
-
PPC-5692, a novel and selective ASIC1a antagonist, exerts analgesic effects across multiple animal pain models
-
Presented at:, Washington, DC, USA, 15-19 November, Abstract 857.14
-
Simard B, Paquet M, Elagoz A et al. PPC-5692, a novel and selective ASIC1a antagonist, exerts analgesic effects across multiple animal pain models. Presented at: 38th Annual Meeting for the Society for Neuroscience Washington, DC, USA, 15-19 November 2008 (Abstract 857.14).
-
(2008)
38th Annual Meeting for the Society for Neuroscience
-
-
Simard, B.1
Paquet, M.2
Elagoz, A.3
-
375
-
-
47949102112
-
Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy induced neuropathy
-
Bordet T, Buisson B, Michaud M et al. Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy induced neuropathy. J. Pharmacol. Exp. Therap. 326 (2), 623-632 (2008).
-
(2008)
J. Pharmacol. Exp. Therap
, vol.326
, Issue.2
, pp. 623-632
-
-
Bordet, T.1
Buisson, B.2
Michaud, M.3
-
376
-
-
0036119716
-
Early clinical experience with the novel NMDA receptor antagonist CNS 5161
-
Walters R, Bradford A P J, Fischer J et al. Early clinical experience with the novel NMDA receptor antagonist CNS 5161. Br J Clin Pharmacol. 53 (3), 305-311 (2002).
-
(2002)
Br. J. Clin. Pharmacol.
, vol.53
, Issue.3
, pp. 305-311
-
-
Walters, R.1
Bradford, A.P.J.2
Fischer, J.3
-
377
-
-
6844257516
-
Synthesis and pharmacological evaluation of N- (2, 5-disubstituted phenyl) -N-3-substituted phenyl) -N-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers
-
Hu L-Y, Guo J, Magar SS et al. Synthesis and pharmacological evaluation of N- (2, 5-disubstituted phenyl) -N-3-substituted phenyl) -N-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers. J. Med. Chem. 40, 4281-4289 (1997).
-
(1997)
J. Med. Chem.
, vol.40
, pp. 4281-4289
-
-
L-Y, H.1
Guo, J.2
Magar, S.S.3
-
378
-
-
0037961047
-
Pharmacokinetics and pharmacodynamics of CHF 3381, a novel N-methyl-D-aspartate antagonist, after single oral doses in healthy subjects
-
Tarral A, Dostert P, Guillevic Y et al. Pharmacokinetics and pharmacodynamics of CHF 3381, a novel N-methyl-D-aspartate antagonist, after single oral doses in healthy subjects. J. Clin. Pharm. 43 (8), 901-911 (2003).
-
(2003)
J. Clin. Pharm.
, vol.43
, Issue.8
, pp. 901-911
-
-
Tarral, A.1
Dostert, P.2
Guillevic, Y.3
-
379
-
-
0034982869
-
Preclinical evaluation of CHF3381 as a novel antiepileptic agent
-
Villetti G, Bregola G, Bassani F et al. Preclinical evaluation of CHF3381 as a novel antiepileptic agent. Neuropharmacol. 40, 866 (2001).
-
(2001)
Neuropharmacol.
, vol.40
, pp. 866
-
-
Villetti, G.1
Bregola, G.2
Bassani, F.3
-
380
-
-
0037113355
-
Neuroprotective activity of CHF3381, a putative N-methyl-D-aspartate receptor antagonist
-
Zucchini S, Buzzi A, Bergamaschi M et al. Neuroprotective activity of CHF3381, a putative N-methyl-D-aspartate receptor antagonist. Neuroreport 13, 2071-2074 (2002).
-
(2002)
Neuroreport
, vol.13
, pp. 2071-2074
-
-
Zucchini, S.1
Buzzi, A.2
Bergamaschi, M.3
-
381
-
-
70149113730
-
Neramexane: A moderate-affinity NMDA receptor channel blocker: New prospects and indications
-
Rammes G. Neramexane: a moderate-affinity NMDA receptor channel blocker: new prospects and indications. Exp. Rev. Clin. Pharmacol. 2 (3), 231-238 (2009).
-
(2009)
Exp. Rev. Clin. Pharmacol.
, vol.2
, Issue.3
, pp. 231-238
-
-
Rammes, G.1
-
382
-
-
67650167699
-
Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain
-
Chen SR, Samoriski G, Pan HL. Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain. Neuropharmacol. 57 (2), 121-126 (2009).
-
(2009)
Neuropharmacol.
, vol.57
, Issue.2
, pp. 121-126
-
-
Chen, S.R.1
Samoriski, G.2
Pan, H.L.3
-
383
-
-
27744441873
-
Anti-allodynic interactions between NMDA receptor channel blockers and morphine or clonidine in neuropathic rats
-
Malyshkin AA, Medvedev IO, Danysz W et al. Anti-allodynic interactions between NMDA receptor channel blockers and morphine or clonidine in neuropathic rats. Eur. J. Pharmacol. 519 (1-2), 80-85 (2005).
-
(2005)
Eur. J. Pharmacol.
, vol.519
, Issue.1-2
, pp. 80-85
-
-
Malyshkin, A.A.1
Medvedev, I.O.2
Danysz, W.3
-
384
-
-
35748972058
-
Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia
-
Klein T, Magerl W, Hanschmann A et al. Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia. Eur. J. Pain (Amsterdam, Netherlands) 12 (1), 17-29 (2007).
-
(2007)
Eur. J. Pain (Amsterdam, Netherlands)
, vol.12
, Issue.1
, pp. 17-29
-
-
Klein, T.1
Magerl, W.2
Hanschmann, A.3
-
385
-
-
0036295932
-
Pharmacological characterisation of the spared nerve injury model of neuropathic pain
-
Erichsen HK, Blackburn-Munro G. Pharmacological characterisation of the spared nerve injury model of neuropathic pain. Pain 98 (1-2), 151-161 (2002).
-
(2002)
Pain
, vol.98
, Issue.1-2
, pp. 151-161
-
-
Erichsen, H.K.1
Blackburn-Munro, G.2
-
386
-
-
3242740258
-
Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain
-
Blackburn-Munro G, Bomholt S, Erichsen HK et al. Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain. Neuropharmacol. 47 (3), 351-362 (2004).
-
(2004)
Neuropharmacol.
, vol.47
, Issue.3
, pp. 351-362
-
-
Blackburn-Munro, G.1
Bomholt, S.2
Erichsen, H.K.3
-
387
-
-
63849275646
-
The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: A randomized, double-blind, placebo-controlled, three-way crossover study
-
Gormsen L, Finnerup NB, Almqvist PM et al. The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study. Anesth. Analg. 108 (4), 1311-1319 (2009).
-
(2009)
Anesth. Analg.
, vol.108
, Issue.4
, pp. 1311-1319
-
-
Gormsen, L.1
Finnerup, N.B.2
Almqvist, P.M.3
-
388
-
-
33644828489
-
The structure of a mixed GluR2 ligand-binding core dimer in complex with (S) -glutamate and the antagonist (S) -NS1209
-
Kasper C, Pickering DS, Mirza O et al. The structure of a mixed GluR2 ligand-binding core dimer in complex with (S) -glutamate and the antagonist (S) -NS1209. J. Mol. Biol. 357 (4), 1184-1201 (2006).
-
(2006)
J. Mol. Biol.
, vol.357
, Issue.4
, pp. 1184-1201
-
-
Kasper, C.1
Pickering, D.S.2
Mirza, O.3
-
389
-
-
0027771510
-
Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1, 2-a]imidazole-2, 5 (3H, 6H) -diones, a novel class of potent cognition enhancers
-
Pinza M, Farina C, Cerri A et al. Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1, 2-a]imidazole-2, 5 (3H, 6H) -diones, a novel class of potent cognition enhancers. J. Med. Chem. 36 (26), 4214-4220 (1993).
-
(1993)
J. Med. Chem.
, vol.36
, Issue.26
, pp. 4214-4220
-
-
Pinza, M.1
Farina, C.2
Cerri, A.3
-
390
-
-
41249097096
-
Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain
-
Farina C, Gagliardi S, Ghelardini C et al. Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain. Bioorg. Med. Chem. 16 (6), 3224-3232 (2008).
-
(2008)
Bioorg. Med. Chem.
, vol.16
, Issue.6
, pp. 3224-3232
-
-
Farina, C.1
Gagliardi, S.2
Ghelardini, C.3
-
391
-
-
77953434495
-
Effects of BND-11624 at ionotropic and metabotropic glutamatergic receptors regulating neurotransmitter release in the rat CNS
-
Atlanta, US, 17 November, Abstract 368.2/JJ27
-
Bonanno G, Misiano P, Bonifacino T et al. Effects of BND-11624 at ionotropic and metabotropic glutamatergic receptors regulating neurotransmitter release in the rat CNS. Annual Meeting of the Society for Neuroscience. Atlanta, US, 17 November 2008 (Abstract 368.2/JJ27).
-
(2008)
Annual Meeting of the Society for Neuroscience
-
-
Bonanno, G.1
Misiano, P.2
Bonifacino, T.3
-
392
-
-
77953419216
-
RGH-896 is a novel potent and selective NR2B-NMDA antagonist with efficacy in neuropathic pain models
-
New Orleans, LA, USA, 8-12 November
-
Farkas S, Horvath C, Nagy J et al. RGH-896 is a novel potent and selective NR2B-NMDA antagonist with efficacy in neuropathic pain models. 33rd Annual Meeting of the Society for Neuroscience. New Orleans, LA, USA, 8-12 November 2009.
-
(2009)
33rd Annual Meeting of the Society for Neuroscience
-
-
Farkas, S.1
Horvath, C.2
Nagy, J.3
-
393
-
-
3042634224
-
Oxamides as novel NR2B selective NMDA receptor antagonists
-
Barta-Szalai G, Borza I, Bozo E et al. Oxamides as novel NR2B selective NMDA receptor antagonists. Bioorg. Med. Chem. Lett. 14 (15), 3953-3956 (2004).
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, Issue.15
, pp. 3953-3956
-
-
Barta-Szalai, G.1
Borza, I.2
Bozo, E.3
-
394
-
-
4344601743
-
The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates
-
Palecek J, Neugebauer V, Carltons M, Iyengar S. Willis WD. The effect of a kainate GluR5 receptor antagonist on responses of spinothalamic tract neurons in a model of peripheral neuropathy in primates. Pain 111 (1-2), 151-161 (2004).
-
(2004)
Pain
, vol.111
, Issue.1-2
, pp. 151-161
-
-
Palecek, J.1
Neugebauer, V.2
Carltons, M.3
Iyengar, S.4
Willis, W.D.5
-
395
-
-
61449169060
-
Prodrugs of perzinfotel with improved oral bioavailability
-
Baudy RB, Butera JA, Abou-Gharbia MA et al. Prodrugs of perzinfotel with improved oral bioavailability. J. Med. Chem. 52 (3), 771-778 (2009).
-
(2009)
J. Med. Chem.
, vol.52
, Issue.3
, pp. 771-778
-
-
Baudy, R.B.1
Butera, J.A.2
Abou-Gharbia, M.A.3
-
396
-
-
66249113481
-
Discovery and biological evaluation of novel cyanoguanidine P2X7 antagonists with analgesic activity in a rat model of neuropathic pain
-
Perez-Medrano A, Donnelly-Roberts DL, Honore P et al. Discovery and biological evaluation of novel cyanoguanidine P2X7 antagonists with analgesic activity in a rat model of neuropathic pain. J. Med. Chem. 52, 3366-3376 (2009).
-
(2009)
J. Med. Chem.
, vol.52
, pp. 3366-3376
-
-
Perez-Medrano, A.1
Donnelly-Roberts, D.L.2
Honore, P.3
-
399
-
-
77953438455
-
Analgesic effects of INS48506, a P2X (3) receptor antagonist, in models of acute, inflammatory and neuropathic pain
-
New Orleans, LA, USA, 8-12 November
-
Crean CS, Yerxa BR, Bednarski K et al. Analgesic effects of INS48506, a P2X (3) receptor antagonist, in models of acute, inflammatory and neuropathic pain. 33rd Annual Meeting of the Society for Neuroscience. New Orleans, LA, USA, 8-12 November 2003.
-
(2003)
33rd Annual Meeting of the Society for Neuroscience
-
-
Crean, C.S.1
Yerxa, B.R.2
Bednarski, K.3
-
400
-
-
77953431729
-
3 and P2X2/3 purinergic receptors
-
Abstr. 820.13, San Diego, CA, USA, 3-7 November
-
3 and P2X2/3 purinergic receptors. 37th Annual Meeting of the Society for Neuroscience Abstr. 820.13, San Diego, CA, USA, 3-7 November 2007.
-
(2007)
37th Annual Meeting of the Society for Neuroscience
-
-
Hsu, D.R.1
Z-L, W.2
O'Mohony, D.J.R.3
-
401
-
-
77953467118
-
ABT-894, a neuronal nicotinic receptor agonist, with an improved therapeutic window in preclinical models of neuropathic pain vs. gastrointestinal and CNS side effects
-
Washington, DC, USA, 15-19 November 2008 Abstract 856.20
-
Rueter LE, Curzon P, Kohlhaas K, Gauvin D, Honore P. ABT-894, a neuronal nicotinic receptor agonist, with an improved therapeutic window in preclinical models of neuropathic pain vs. gastrointestinal and CNS side effects. 38th Annual Meeting for the Society for Neuroscience. Washington, DC, USA, 15-19 November 2008 (Abstract 856.20).
-
38th Annual Meeting for the Society for Neuroscience
-
-
Rueter, L.E.1
Curzon, P.2
Kohlhaas, K.3
Gauvin, D.4
Honore, P.5
-
402
-
-
77953454544
-
Novel neuronal nicotinic receptor selective compounds for the treatment of acute, chronic and neurpathic pain
-
Lippiello PM, Gatto GJ, Jordan KG, Bencherif M. Novel neuronal nicotinic receptor selective compounds for the treatment of acute, chronic and neurpathic pain. Eur. Neuropsychopharmacol. 17 (4), 252 (2007).
-
(2007)
Eur. Neuropsychopharmacol.
, vol.17
, Issue.4
, pp. 252
-
-
Lippiello, P.M.1
Gatto, G.J.2
Jordan, K.G.3
Bencherif, M.4
-
403
-
-
77953403550
-
Novel opioidnicotinic combination drug therapy for pain
-
29 Abstract, 7 May
-
Holtman J, Johnson-Hardy J, Crooks P, Chakraborty U, Wala E. Novel opioidnicotinic combination drug therapy for pain. 28th Annual Scientific Meeting of the American Pain Society 29 Abstract. 216, 7 May 2009.
-
(2009)
28th Annual Scientific Meeting of the American Pain Society
, vol.216
-
-
Holtman, J.1
Johnson-Hardy, J.2
Crooks, P.3
Chakraborty, U.4
Wala, E.5
-
404
-
-
0037849869
-
Peripheral and central sites of action for A-85380 in the spinal nerve ligation model of neuropathic pain
-
Rueter LE, Kohlhaas KL, Curzon P, Surowy CS, Meyer MD. Peripheral and central sites of action for A-85380 in the spinal nerve ligation model of neuropathic pain. Pain 103 (3), 269-276 (2003).
-
(2003)
Pain
, vol.103
, Issue.3
, pp. 269-276
-
-
Rueter, L.E.1
Kohlhaas, K.L.2
Curzon, P.3
Surowy, C.S.4
Meyer, M.D.5
-
405
-
-
67650608109
-
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and pain
-
Dunlop J, Vasilyev D, Lu P, Cummons T, Bowlby MR. Hyperpolarization- activated cyclic nucleotide-gated (HCN) channels and pain. Curr. Pharm. Des. 15, 1767-1772 (2009).
-
(2009)
Curr. Pharm. Des.
, vol.15
, pp. 1767-1772
-
-
Dunlop, J.1
Vasilyev, D.2
Lu, P.3
Cummons, T.4
Bowlby, M.R.5
-
406
-
-
51749096417
-
Characteristic of HCN channels and their participation in neuropathic pain
-
Jiang YQ, Sun Q, Tu HY, Wan Y. Characteristic of HCN channels and their participation in neuropathic pain. Neurochem. Res. 33, 1979-1989 (2008).
-
(2008)
Neurochem. Res.
, vol.33
, pp. 1979-1989
-
-
Jiang, Y.Q.1
Sun, Q.2
Tu, H.Y.3
Wan, Y.4
-
407
-
-
62649132236
-
HCN channels as targets for drug discovery
-
Maher MP, Wu N-T, Guo H-Q, Dubin AE, Chaplan SR, Wickenden AD: HCN channels as targets for drug discovery. Comb. Chem. High Through. Screen. 12 (1), 64-72 (2009).
-
(2009)
Comb. Chem. High Through. Screen
, vol.12
, Issue.1
, pp. 64-72
-
-
Maher, M.P.1
Wu, N.-T.2
Guo, H.-Q.3
Dubin, A.E.4
Chaplan, S.R.5
Wickenden, A.D.6
|