Analgesic profile of the nicotinic acetylcholine receptor agonists, (+)-epibatidine and ABT-594 in models of persistent inflammatory and neuropathic pain

Pain

Volumn 86, Issue 1-2, 2000, Pages 113-118

  Kesingland, A C ^a   Gentry, C T ^a   Panesar, M S ^a   Bowes, M A ^a   Vernier, J M ^b   Cube, R ^b   Walker, K ^a   Urban, L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

(+) Epibatidine; ABT 594; Anti nociception; Inflammatory pain; Mechanical hyperalgesia; nAChR; Neuropathic pain

Indexed keywords

5 (2 AZETIDINYLMETHOXY) 2 CHLOROPYRIDINE; EPIBATIDINE; FREUND ADJUVANT; NICOTINIC AGENT; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE;

ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CIRCLING BEHAVIOR; CONTROLLED STUDY; DOSE RESPONSE; HYPERALGESIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TAIL FLICK TEST;

ANALGESICS, NON-NARCOTIC; ANIMALS; ARTHRITIS, EXPERIMENTAL; AZETIDINES; BICYCLO COMPOUNDS, HETEROCYCLIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FREUND'S ADJUVANT; HYPERALGESIA; INFLAMMATION; MALE; MUSCULOSKELETAL EQUILIBRIUM; NICOTINIC AGONISTS; PAIN; PAIN MEASUREMENT; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, NICOTINIC; SCIATIC NEUROPATHY;

EID: 0034193948     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(00)00233-5     Document Type: Article

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