Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain

Neuropharmacology

Volumn 47, Issue 3, 2004, Pages 351-362

  Blackburn Munro, Gordon ^a   Bomholt, Signe F ^a   Erichsen, Helle K ^a  

^a NEUROSEARCH A S   (Denmark)

Author keywords

Central sensitisation; Glutamate; Kainate receptor; Neuropathic pain; Rat formalin test; Tail flick test

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; AMPA RECEPTOR ANTAGONIST; MORPHINE; NS 1209;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; COLD SENSITIVITY; DRUG EFFECT; HOT PLATE TEST; HYPERALGESIA; LATENT PERIOD; MALE; MOTOR PERFORMANCE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SYSTEMIC THERAPY; TAIL FLICK TEST;

ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MORPHINE; NARCOTICS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PERIPHERAL NERVOUS SYSTEM DISEASES; PYRROLES; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, KAINIC ACID; TETRAHYDROISOQUINOLINES; TIME FACTORS;

EID: 3242740258     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.04.007     Document Type: Article

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