Functional Regulation of P2X6 Receptors by N-Linked Glycosylation: Identification of a Novel αβ-Methylene ATP-Sensitive Phenotype

Molecular Pharmacology

Volumn 65, Issue 4, 2004, Pages 979-985

  Jones, Clare A ^a,c   Vial, Catherine ^b   Sellers, Lynda A ^a,d   Humphrey, Pat P A ^a,e   Evans, Richard J ^b   Chessell, Iain P ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c ITIS UMR 6150 CNRS   (France)

^d BABRAHAM INSTITUTE   (United Kingdom)

^e Advanced Medicine Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' O (2,4,6 TRINITROPHENYLADENOSINE TRIPHOSPHATE); ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; GLYCOSIDASE; ISOPYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',5' DISULFONATE; N GLYCOSIDASE F; PURINE P2X1 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2X6 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; PYRIDOXAL 5 PHOSPHATE; RECEPTOR SUBUNIT; RECOMBINANT RECEPTOR; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ALPHA,BETA-METHYLENEADENOSINE 5'-TRIPHOSPHATE; DRUG DERIVATIVE; PROTEIN SUBUNIT; PURINE P2 RECEPTOR;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; EMBRYO; GLYCOSYLATION; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; IC 50; KIDNEY CELL; MOLECULAR WEIGHT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SLOW INWARD CURRENT; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DRUG EFFECT; METABOLISM; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL MEMBRANE; CELLS, CULTURED; GLYCOSYLATION; HUMANS; PHENOTYPE; PROTEIN SUBUNITS; RATS; RECEPTORS, PURINERGIC P2;

EID: 1842481005     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.65.4.979     Document Type: Article

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