TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: Comparison with reference analgesics

Pain

Volumn 96, Issue 1-2, 2002, Pages 99-105

  Honore, Prisca ^a   Mikusa, Joseph ^a   Bianchi, Bruce ^a   McDonald, Heath ^a   Cartmell, Jayne ^a   Faltynek, Connie ^a   Jarvis, Michael F ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Abdominal constrictions; P2X3 receptors; TNP ATP; Visceral pain

Indexed keywords

2' O (TRINITROPHENYL)ADENOSINE 5' MONOPHOSPHATE; 2' O (TRINITROPHENYL)ADENOSINE 5' TRIPHOSPHATE; ACETIC ACID; ANALGESIC AGENT; CELECOXIB; DIINOSINE PENTAPHOSPHATE; GABAPENTIN; IP 51; MORPHINE; PHOSPHATE; PURINE P2X RECEPTOR; PURINE P2X1 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2X3 RECEPTOR ANTAGONIST; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SURAMIN; UNCLASSIFIED DRUG;

ABDOMEN; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; ASSAY; CALCIUM TRANSPORT; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; IC 50; IN VITRO STUDY; MALE; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; SPINAL GANGLION; VISCERAL PAIN;

ABDOMEN; ACETIC ACID; ADENOSINE TRIPHOSPHATE; ANALGESICS; ANIMALS; ANTINEOPLASTIC AGENTS; BEHAVIOR, ANIMAL; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MICE, INBRED STRAINS; NOCICEPTORS; PAIN; PLATELET AGGREGATION INHIBITORS; PYRIDOXAL PHOSPHATE; RECEPTORS, PURINERGIC P2; SURAMIN;

EID: 0036214576     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(01)00434-1     Document Type: Article

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