메뉴 건너뛰기




Volumn 286, Issue 1, 1998, Pages 311-320

α5 Subunit alters desensitization, pharmacology, Ca++ permeability and Ca++ modulation of human neuronal α3 nicotinic receptors

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; ACETYLCHOLINE; CALCIUM ION; COMPLEMENTARY DNA; COMPLEMENTARY RNA; CYTISINE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT;

EID: 0031821563     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (225)

References (51)
  • 1
    • 0027095934 scopus 로고
    • Calcium permeability and modulation of nicotinic acetylcholine receptor-channels in rat parasympathetic neurons
    • Adams D and Nutter T (1992) Calcium permeability and modulation of nicotinic acetylcholine receptor-channels in rat parasympathetic neurons. J Physiol 86:67-76.
    • (1992) J Physiol , vol.86 , pp. 67-76
    • Adams, D.1    Nutter, T.2
  • 2
    • 0029008226 scopus 로고
    • Mechanism for modulation of nicotinic acetylcholine receptors that can influence synaptic transmission
    • Amador M and Dani J (1995) Mechanism for modulation of nicotinic acetylcholine receptors that can influence synaptic transmission. J Neurosci 15:4525-4532.
    • (1995) J Neurosci , vol.15 , pp. 4525-4532
    • Amador, M.1    Dani, J.2
  • 3
    • 0025856536 scopus 로고
    • Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure
    • Anand R, Conroy WG, Schoepfer R, Whiting P and Lindstrom J (1991) Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure. J Biol Chem 266:11192-11198.
    • (1991) J Biol Chem , vol.266 , pp. 11192-11198
    • Anand, R.1    Conroy, W.G.2    Schoepfer, R.3    Whiting, P.4    Lindstrom, J.5
  • 4
    • 0025297269 scopus 로고
    • Nucleotide sequence of the human nicotinic acetylcholine receptor β2 subunit gene
    • Anand R and Lindstrom J (1990) Nucleotide sequence of the human nicotinic acetylcholine receptor β2 subunit gene. Nucleic Acids Res 18:4272.
    • (1990) Nucleic Acids Res , vol.18 , pp. 4272
    • Anand, R.1    Lindstrom, J.2
  • 5
    • 0027214596 scopus 로고
    • Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal α7 nicotinic receptor
    • Bertrand D, Galzi JL, Devillers-Thiery A, Bertrand S and Changeux JP (1993) Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal α7 nicotinic receptor. Proc Natl Acad Sci USA 90:6971-6975.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6971-6975
    • Bertrand, D.1    Galzi, J.L.2    Devillers-Thiery, A.3    Bertrand, S.4    Changeux, J.P.5
  • 7
    • 0026335951 scopus 로고
    • β subunits determine the time course of desensitization in rat α3 neuronal nicotinic acetylcholine receptors
    • Cachelin AB and Jaggi R (1991) β subunits determine the time course of desensitization in rat α3 neuronal nicotinic acetylcholine receptors. Pflügers Arch 419:579-582.
    • (1991) Pflügers Arch , vol.419 , pp. 579-582
    • Cachelin, A.B.1    Jaggi, R.2
  • 8
    • 0028982464 scopus 로고
    • α-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability
    • Castro N and Albuquerque E (1995) α-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability. Biophys J 68:516-524.
    • (1995) Biophys J , vol.68 , pp. 516-524
    • Castro, N.1    Albuquerque, E.2
  • 9
    • 0026502373 scopus 로고
    • Neuronal-type α-bungarotoxin receptors and the α5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines
    • Chini B, Clementi F, Hukovic N and Sher E (1992) Neuronal-type α-bungarotoxin receptors and the α5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines. Proc Natl Acad Sci USA 89:1572-1576.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1572-1576
    • Chini, B.1    Clementi, F.2    Hukovic, N.3    Sher, E.4
  • 10
    • 0028940759 scopus 로고
    • Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions
    • Conroy WG and Berg DK (1995) Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions. J Biol Chem 270:4424-4431.
    • (1995) J Biol Chem , vol.270 , pp. 4424-4431
    • Conroy, W.G.1    Berg, D.K.2
  • 11
    • 0026754804 scopus 로고
    • The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain
    • Conroy WG, Vernallis AB and Berg DK (1992) The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain. Neuron 9:679-691.
    • (1992) Neuron , vol.9 , pp. 679-691
    • Conroy, W.G.1    Vernallis, A.B.2    Berg, D.K.3
  • 12
    • 0025828670 scopus 로고
    • Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor
    • Cooper E, Couturier S and Ballivet M (1991) Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor. Nature (Lond) 350: 235-238.
    • (1991) Nature (Lond) , vol.350 , pp. 235-238
    • Cooper, E.1    Couturier, S.2    Ballivet, M.3
  • 13
    • 0028144005 scopus 로고
    • Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes
    • Covernton PJ, Kojima H, Sivilotti LG, Gibb AJ and Colquhoun D (1994) Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes. J Physiol (Lond) 481:27-34.
    • (1994) J Physiol (Lond) , vol.481 , pp. 27-34
    • Covernton, P.J.1    Kojima, H.2    Sivilotti, L.G.3    Gibb, A.J.4    Colquhoun, D.5
  • 14
    • 0029072385 scopus 로고
    • Structure and function of glutamate and nicotinic acetylcholine receptors
    • Dani JA and Mayer ML (1995) Structure and function of glutamate and nicotinic acetylcholine receptors. Curr Opinion Neurobiol 5:310-317.
    • (1995) Curr Opinion Neurobiol , vol.5 , pp. 310-317
    • Dani, J.A.1    Mayer, M.L.2
  • 15
    • 0031000154 scopus 로고    scopus 로고
    • Activation of the recombinant human α7 nicotinic acetylcholine receptor significantly raises intracellular free calcium
    • Delbono O, Gopalakrishnan M, Renganathan M, Monteggia L, Messi M and Sullivan J (1997) Activation of the recombinant human α7 nicotinic acetylcholine receptor significantly raises intracellular free calcium. J Pharmacol Exp Ther 280:428-438.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 428-438
    • Delbono, O.1    Gopalakrishnan, M.2    Renganathan, M.3    Monteggia, L.4    Messi, M.5    Sullivan, J.6
  • 16
    • 0025968656 scopus 로고
    • Pharmacological and functional diversity of neuronal nicotinic acetylcholine receptors
    • Deneris ES, Connolly J, Rogers SW and Duvoisin R (1991) Pharmacological and functional diversity of neuronal nicotinic acetylcholine receptors. Trends Pharmacol Sci 12:34-40.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 34-40
    • Deneris, E.S.1    Connolly, J.2    Rogers, S.W.3    Duvoisin, R.4
  • 17
    • 0030841113 scopus 로고    scopus 로고
    • Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine
    • Fenster CP, Rains MF, Noerager B, Quick MW and Lester RA (1997) Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine. J Neurosci 17:5747-5755.
    • (1997) J Neurosci , vol.17 , pp. 5747-5755
    • Fenster, C.P.1    Rains, M.F.2    Noerager, B.3    Quick, M.W.4    Lester, R.A.5
  • 18
    • 0026021933 scopus 로고
    • Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia
    • Fieber LA and Adams DJ (1991) Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. J Physiol (Lond) 434:215-237.
    • (1991) J Physiol (Lond) , vol.434 , pp. 215-237
    • Fieber, L.A.1    Adams, D.J.2
  • 19
    • 0026593533 scopus 로고
    • A subtype of nicotinic cholinergic receptor in rat brain is composed of α4 and β2 subunits and is upregulated by chronic nicotinic treatment
    • Flores CM, Rogers SW, Pabreza LA, Wolfe BB and Keller KJ (1992) A subtype of nicotinic cholinergic receptor in rat brain is composed of α4 and β2 subunits and is upregulated by chronic nicotinic treatment. Mol Pharmacol 41:31-37.
    • (1992) Mol Pharmacol , vol.41 , pp. 31-37
    • Flores, C.M.1    Rogers, S.W.2    Pabreza, L.A.3    Wolfe, B.B.4    Keller, K.J.5
  • 20
    • 0030460681 scopus 로고    scopus 로고
    • Muscle-type nicotinic acetylcholine receptor δ subunit determines sensitivity to noncompetitive inhibitors, while the γ subunit regulates divalent permeability
    • Francis M and Papke R (1996) Muscle-type nicotinic acetylcholine receptor δ subunit determines sensitivity to noncompetitive inhibitors, while the γ subunit regulates divalent permeability. Neuropharmacology 35:1547-1556.
    • (1996) Neuropharmacology , vol.35 , pp. 1547-1556
    • Francis, M.1    Papke, R.2
  • 21
    • 0029958046 scopus 로고    scopus 로고
    • Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor
    • Galzi J, Bertrand S, Corringer P, Changeux J and Bertrand D (1996) Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor. The EMBO Journal 15:5824-5832.
    • (1996) The EMBO Journal , vol.15 , pp. 5824-5832
    • Galzi, J.1    Bertrand, S.2    Corringer, P.3    Changeux, J.4    Bertrand, D.5
  • 23
    • 0028838303 scopus 로고
    • Comparative pharmacology of epibatidine - A potent agonist for neuronal nicotinic acetylcholine receptors
    • Gerzanich V, Peng X, Wang F, Wells G, Anand R, Fletcher S and Lindstrom J (1995) Comparative pharmacology of epibatidine - a potent agonist for neuronal nicotinic acetylcholine receptors. Mol Pharmacol 48:774-782.
    • (1995) Mol Pharmacol , vol.48 , pp. 774-782
    • Gerzanich, V.1    Peng, X.2    Wang, F.3    Wells, G.4    Anand, R.5    Fletcher, S.6    Lindstrom, J.7
  • 24
    • 0030754814 scopus 로고    scopus 로고
    • Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area
    • Goldner FM, Dineley KT and Patrick JW (1997) Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area. Neuroreport 8:2739-2742.
    • (1997) Neuroreport , vol.8 , pp. 2739-2742
    • Goldner, F.M.1    Dineley, K.T.2    Patrick, J.W.3
  • 25
    • 0027956268 scopus 로고
    • Agonist and antagonist effects of nicotine on chick neuronal nicotinic receptors are defined by α and β subunits
    • Hussy N, Ballivet M and Bertrand D (1994) Agonist and antagonist effects of nicotine on chick neuronal nicotinic receptors are defined by α and β subunits. J Neurophysiol 72:1317-1326.
    • (1994) J Neurophysiol , vol.72 , pp. 1317-1326
    • Hussy, N.1    Ballivet, M.2    Bertrand, D.3
  • 26
    • 0029593370 scopus 로고
    • Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
    • Karlin A and Akabas MH (1995) Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron 15:1231-1244.
    • (1995) Neuron , vol.15 , pp. 1231-1244
    • Karlin, A.1    Akabas, M.H.2
  • 27
    • 0028922693 scopus 로고
    • Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells
    • Le Novere N and Changeux J-P (1995) Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells. J Mol Evol 40:155-172.
    • (1995) J Mol Evol , vol.40 , pp. 155-172
    • Le Novere, N.1    Changeux, J.-P.2
  • 28
    • 0029908722 scopus 로고    scopus 로고
    • Neuronal nicotinic receptor α6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain
    • Le Novere N, Zoli M and Changeux J-P (1996) Neuronal nicotinic receptor α6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain. Eur J Neurosci 8:2428-2439.
    • (1996) Eur J Neurosci , vol.8 , pp. 2428-2439
    • Le Novere, N.1    Zoli, M.2    Changeux, J.-P.3
  • 30
    • 0029690580 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors
    • (Narahashi T ed) Plenum, New York
    • Lindstrom JM (1996) Neuronal nicotinic acetylcholine receptors, in Ion Channels, vol. IV (Narahashi T ed) pp 377-450 Plenum, New York.
    • (1996) Ion Channels , vol.4 , pp. 377-450
    • Lindstrom, J.M.1
  • 31
    • 0025934097 scopus 로고
    • Both α- and β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors
    • Luetje CW and Patrick J (1991) Both α- and β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors. J Neurosci 11:837-845.
    • (1991) J Neurosci , vol.11 , pp. 837-845
    • Luetje, C.W.1    Patrick, J.2
  • 34
    • 0028965629 scopus 로고
    • Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons
    • McGehee DS and Role LW (1995) Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annual Review of Physiology 57:521-546.
    • (1995) Annual Review of Physiology , vol.57 , pp. 521-546
    • McGehee, D.S.1    Role, L.W.2
  • 35
    • 0026580364 scopus 로고
    • Calcium influx through nicotinic receptor in rat central neurons: Its relevance to cellular regulation
    • Mulle C, Choquet D, Korn H and Changeux J-P (1992) Calcium influx through nicotinic receptor in rat central neurons: Its relevance to cellular regulation. Neuron 8:135-143.
    • (1992) Neuron , vol.8 , pp. 135-143
    • Mulle, C.1    Choquet, D.2    Korn, H.3    Changeux, J.-P.4
  • 36
    • 0027290947 scopus 로고
    • The kinetic properties of neuronal nicotinic receptors: Genetic basis of functional diversity
    • Papke RL (1993) The kinetic properties of neuronal nicotinic receptors: Genetic basis of functional diversity. Prog Neurobiol 41:509-531.
    • (1993) Prog Neurobiol , vol.41 , pp. 509-531
    • Papke, R.L.1
  • 37
    • 0028153758 scopus 로고
    • Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit
    • Papke RL and Heinemann SF (1993) Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit. Mol Pharmacol 45:142-149.
    • (1993) Mol Pharmacol , vol.45 , pp. 142-149
    • Papke, R.L.1    Heinemann, S.F.2
  • 38
    • 0028136165 scopus 로고
    • Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover
    • Peng X, Gerzanich V, Anand R, Whiting P and Lindstrom J (1994) Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover. Mol Pharmacol 46:523-530.
    • (1994) Mol Pharmacol , vol.46 , pp. 523-530
    • Peng, X.1    Gerzanich, V.2    Anand, R.3    Whiting, P.4    Lindstrom, J.5
  • 39
    • 0029670191 scopus 로고    scopus 로고
    • Functional contributions of α5 subunit to neuronal acetylcholine receptor channels
    • Ramirez-Latorre JA, Yu CR, Qu X, Perin F, Karlin A and Role L (1996) Functional contributions of α5 subunit to neuronal acetylcholine receptor channels. Nature (Lond) 380:347-351.
    • (1996) Nature (Lond) , vol.380 , pp. 347-351
    • Ramirez-Latorre, J.A.1    Yu, C.R.2    Qu, X.3    Perin, F.4    Karlin, A.5    Role, L.6
  • 40
    • 0028814237 scopus 로고
    • Comparison of quantitative calcium flux through NMDA, ATP, and ACh receptor channels
    • Rogers M and Dani J (1995) Comparison of quantitative calcium flux through NMDA, ATP, and ACh receptor channels. Biophys J 68:501-506.
    • (1995) Biophys J , vol.68 , pp. 501-506
    • Rogers, M.1    Dani, J.2
  • 41
    • 0026874825 scopus 로고
    • Diversity in primary structure and function of neuronal nicotinic acetylcholine receptor channels
    • Role LW (1992) Diversity in primary structure and function of neuronal nicotinic acetylcholine receptor channels. Curr Opin Neurobiol 2:254-262.
    • (1992) Curr Opin Neurobiol , vol.2 , pp. 254-262
    • Role, L.W.1
  • 42
    • 0027398069 scopus 로고
    • The diversity of neuronal nicotinic acetylcholine receptors
    • Sargent PB (1993) The diversity of neuronal nicotinic acetylcholine receptors. Annu Rev Neurosci 16:403-443.
    • (1993) Annu Rev Neurosci , vol.16 , pp. 403-443
    • Sargent, P.B.1
  • 43
    • 0027518923 scopus 로고
    • Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium
    • Seguela P, Wadiche J, Dineley-Miller K, Dani J and Patrick J (1993) Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium. J Neurosci 13:596-604.
    • (1993) J Neurosci , vol.13 , pp. 596-604
    • Seguela, P.1    Wadiche, J.2    Dineley-Miller, K.3    Dani, J.4    Patrick, J.5
  • 44
    • 0021365202 scopus 로고
    • Calcium entry through acetylcholine channels can activate potassium conductance in bullfrog sympathetic neurons
    • Tokimasa T and North RA (1984) Calcium entry through acetylcholine channels can activate potassium conductance in bullfrog sympathetic neurons. Brain Res 295: 364-367.
    • (1984) Brain Res , vol.295 , pp. 364-367
    • Tokimasa, T.1    North, R.A.2
  • 45
    • 0027538222 scopus 로고
    • Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes
    • Vernallis AB, Conroy WG and Berg DK (1993) Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes. Neuron 10:451-464.
    • (1993) Neuron , vol.10 , pp. 451-464
    • Vernallis, A.B.1    Conroy, W.G.2    Berg, D.K.3
  • 46
    • 0026586188 scopus 로고
    • Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors
    • Vernino S, Amador M, Luetje CW, Patrick J and Dani JA (1992) Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors. Neuron 8:127-134.
    • (1992) Neuron , vol.8 , pp. 127-134
    • Vernino, S.1    Amador, M.2    Luetje, C.W.3    Patrick, J.4    Dani, J.A.5
  • 47
    • 0024474491 scopus 로고
    • Distribution of α2, α3, α4 and β2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat
    • Wada E, Wada K, Boulter J, Denaris E, Heinemann S, Patrick J and Swanson LW (1989) Distribution of α2, α3, α4 and β2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat. J Comp Neurol 284:314-335.
    • (1989) J Comp Neurol , vol.284 , pp. 314-335
    • Wada, E.1    Wada, K.2    Boulter, J.3    Denaris, E.4    Heinemann, S.5    Patrick, J.6    Swanson, L.W.7
  • 48
    • 0029998344 scopus 로고    scopus 로고
    • Assembly of the human neuronal nicotinic receptor α3 subunit with β2, β4, and α5 subunits
    • Wang F, Gerzanich V, Wells GB, Anand R, Peng X, Keyser K and Lindstrom J (1996) Assembly of the human neuronal nicotinic receptor α3 subunit with β2, β4, and α5 subunits. J Biol Chem 271:1656-17665.
    • (1996) J Biol Chem , vol.271 , pp. 1656-17665
    • Wang, F.1    Gerzanich, V.2    Wells, G.B.3    Anand, R.4    Peng, X.5    Keyser, K.6    Lindstrom, J.7
  • 49
    • 0022531880 scopus 로고
    • Purification and characterization of a nicotinic acetylcholine receptor from chick brain
    • Whiting PJ and Lindstrom JM (1986) Purification and characterization of a nicotinic acetylcholine receptor from chick brain. Biochemistry 25:2082-2093.
    • (1986) Biochemistry , vol.25 , pp. 2082-2093
    • Whiting, P.J.1    Lindstrom, J.M.2
  • 50
    • 0023751963 scopus 로고
    • Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies
    • Whiting P and Lindstrom J (1988) Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies. J Neurosci 8:3395-3404.
    • (1988) J Neurosci , vol.8 , pp. 3395-3404
    • Whiting, P.1    Lindstrom, J.2
  • 51
    • 0028859846 scopus 로고
    • Pharmacological and physiological properties of a putative ganglionic nicotinic receptor, α3β4, expressed in transfected eucaryotic cells
    • Wong ET, Holstad SG, Mennerick SJ, Hong SE, Zorumski CF and Isenberg KE (1995) Pharmacological and physiological properties of a putative ganglionic nicotinic receptor, α3β4, expressed in transfected eucaryotic cells. Mol Brain Res 28:101-109.
    • (1995) Mol Brain Res , vol.28 , pp. 101-109
    • Wong, E.T.1    Holstad, S.G.2    Mennerick, S.J.3    Hong, S.E.4    Zorumski, C.F.5    Isenberg, K.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.