Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors

Journal of Neuroscience

Volumn 21, Issue 20, 2001, Pages 8026-8033

  Voilley, Nicolas ^a   De Weille, Jan ^a   Mamet, Julien ^a   Lazdunski, Michel ^a  

^a CNRS   (France)

Author keywords

Acid sensing ion channel; Aspirin; Dorsal root ganglion; Inflammation; Nociception; NSAID

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ACETYLSALICYLIC ACID; ACID SENSING ION CHANNEL; AMYLOID BETA PROTEIN; DEXAMETHASONE; DICLOFENAC; FLURBIPROFEN; IBUPROFEN; ION CHANNEL; ISOLECTIN B4; ISOPROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; NORDIHYDROGUAIARETIC ACID; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN ASIC1A; SUBSTANCE P; UNCLASSIFIED DRUG; VANILLOID RECEPTOR; ZILEUTON;

ACIDOSIS; ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; HYPERALGESIA; INFLAMMATION; ISCHEMIA; MALE; MOLECULAR CLONING; NOCICEPTIVE RECEPTOR; NONHUMAN; PAIN; PH; PRIORITY JOURNAL; RAT; SENSOR; SENSORY NERVE CELL; SPINAL GANGLION;

EID: 0035887733     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-20-08026.2001     Document Type: Article

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