The tetrodotoxin-resistant Na+ channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice

Journal of Physiology

Volumn 550, Issue 3, 2003, Pages 921-926

  Roza, Carolina ^a,c   Laird, Jennifer M A ^a,d   Souslova, Veronika ^b,e   Wood, John N ^b   Cervero, Fernando ^a,f  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c INSTITUTO DE NEUROCIENCIAS   (Spain)

^d ASTRAZENECA   (United Kingdom)

^e Novartis Inst for Medical Research   (United Kingdom)

^f MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHANNEL; SODIUM ION; TETRODOTOXIN; SODIUM CHANNEL NAV1.8;

ACTION POTENTIAL; ALPHA CHAIN; ANIMAL CELL; ARTICLE; AXONAL INJURY; CELL POPULATION; CONTROLLED STUDY; FEMALE; GENOTYPE; IN VITRO STUDY; MALE; MOUSE; NERVE CONDUCTION; NERVE FIBER; NEUROMA; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; SAPHENOUS NERVE; SENSORY NERVE; STATISTICAL ANALYSIS; ADULT; AFTERDISCHARGE; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL ACTIVITY; ELECTROPHYSIOLOGY PARAMETERS; FIRING RATE; KNOCKOUT MOUSE; MECHANICAL STIMULATION; MECHANOSENSITIVITY; NERVE CELL STIMULATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPONTANEOUS ACTIVITY; WILD TYPE;

ANIMALS; AXONS; AXOTOMY; ELECTROPHYSIOLOGY; FEMALE; MALE; MECHANORECEPTORS; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEUROMA; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN;

EID: 0041974814     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.046110     Document Type: Article

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