Neuroprotective activity of CHF3381, a putative N-methyl-D-aspartate receptor antagonist

NeuroReport

Volumn 13, Issue 16, 2002, Pages 2071-2074

  Zucchini, Silvia ^a   Buzzi, Andrea ^a   Bergamaschi, Marco ^a,b   Pietra, Claudio ^b   Villetti, Gino ^b   Simonato, Michele ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b CHIESI FARMACEUTICI S P A   (Italy)

Author keywords

Excitotoxicity; Fluoro Jade B; Kainate; N methyl D aspartate (NMDA); Neurodegeneration

Indexed keywords

CHF 3381; DIZOCILPINE; KAINIC ACID; LAMOTRIGINE; N (2 INDANYL)GLYCINAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE SEVERITY; DRUG EFFECT; MALE; MOUSE; NEUROLOGIC DISEASE; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ANIMALS; ANTICONVULSANTS; CELL DEATH; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; HIPPOCAMPUS; HISTOLOGICAL TECHNIQUES; INDANS; KAINIC ACID; MALE; MICE; NEUROPROTECTIVE AGENTS; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; TRIAZINES;

EID: 0037113355     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200211150-00016     Document Type: Article

References (19)

1. Brauner-Osborne H, Egebjerg J, Nielsen E et al. J Med Chem 43, 2609-2645 (2000).
2. Chiamulera C, Costa S and Reggiani A. Psychopharmacology 102, 551-552 (1990).
3. Dingledine R, McBain CJ and McNamara JO. Trends Pharmacol Sci 11, 334-833 (1990).
4. Gandolfi O, Bonfante V, Voltattorni M et al. Pharmacol Biochem Behav 70, 157-166 (2001).
5. Hopkins KJ, Wang G and Schmued LC. Brain Res 864, 69-80 (2000).
6. Janumpalli S, Butler LS, MacMillan LB et al. J Neurosci 18, 2004-2008 (1998).
7. Lee JM, Zipfel GJ and Choi DW. Nature 399(suppl 6738), A7-A14 (1999).
8. Maj R, Fariello RG, Ukmar G et al. Eur J Pharmacol 359, 27-32 (1998).
9. Miller AA, Wheatley P, Sawyer DA et al. Epilepsia 27, 483-489 (1986).
10. Montoliu C, Humet M, Canales JJ et al. J Pharmacol Exp Ther 301, 29-36, (2001).
11. Paxinos G and Franklin KBJ. The Mouse Brain in Stereotaxic Coordinates 2nd Edn. New York: Academic Press; 2001.
12. Ravizza T, Moneta D, Bottazzi B et al. Neuroscience 105, 43-53 (2001).
13. Rogawski MA, Yamaguchi SI, Jones SM et al. J Pharmacol Exp Ther 259, 30-37 (1991).
14. Schmued LC and Hopkins KJ. Brain Res 874, 123-130 (2000).
15. Sperk G. Prog Neurobiol 42, 1-32 (1994).
16. Sperk G, Lassmann H, Baran H et al. Neuroscience 10, 1301-1315 (1983).
17. Tai KK, Blondelle SE, Ostresh JM et al. Proc Natl Acad Sci USA 98, 3519-3524 (2001).
18. Villetti G, Bregola G, Bassani F et al. Neuropharmacology 40, 866-878 (2001).
19. Woodruff GN, Foster AC, Gill R et al. Neuropharmacology 26, 903-909 (1987).