-
1
-
-
0012431804
-
-
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
-
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2003;26:S5-20.
-
(2003)
Diabetes Care
, vol.26
-
-
-
2
-
-
0027370108
-
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993;329:977-86
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993;329:977-86.
-
-
-
-
3
-
-
0035085643
-
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol
-
Ryan EA, Lakey JR, Rajotte RV, Korbutt GS, Kin T, Imes S, Rabinovitch A, Elliott JF, Bigam D, Kneteman NM, Warnock GL, Larsen I, Shapiro AM. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes. 2001;50:710-9.
-
(2001)
Diabetes
, vol.50
, pp. 710-719
-
-
Ryan, E.A.1
Lakey, J.R.2
Rajotte, R.V.3
Korbutt, G.S.4
Kin, T.5
Imes, S.6
Rabinovitch, A.7
Elliott, J.F.8
Bigam, D.9
Kneteman, N.M.10
Warnock, G.L.11
Larsen, I.12
Shapiro, A.M.13
-
4
-
-
0034721255
-
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
-
Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343:230-8.
-
(2000)
N Engl J Med
, vol.343
, pp. 230-238
-
-
Shapiro, A.M.1
Lakey, J.R.2
Ryan, E.A.3
Korbutt, G.S.4
Toth, E.5
Warnock, G.L.6
Kneteman, N.M.7
Rajotte, R.V.8
-
5
-
-
21344462346
-
Five-year follow-up after clinical islet transplantation
-
Ryan EA, Paty BW, Senior PA, Bigam D, Alfadhli E, Kneteman NM, Lakey JR, Shapiro AM. Five-year follow-up after clinical islet transplantation. Diabetes. 2005;54:2060-9.
-
(2005)
Diabetes
, vol.54
, pp. 2060-2069
-
-
Ryan, E.A.1
Paty, B.W.2
Senior, P.A.3
Bigam, D.4
Alfadhli, E.5
Kneteman, N.M.6
Lakey, J.R.7
Shapiro, A.M.8
-
6
-
-
33749070784
-
International trial of the Edmonton protocol for islet transplantation
-
Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, Polonsky KS, Reems JA, Bretzel RG, Bertuzzi F, Froud T, Kandaswamy R, Sutherland DE, Eisenbarth G, Segal M, Preiksaitis J, Korbutt GS, Barton FB, Viviano L, Seyfert-Margolis V, Bluestone J, Lakey JR. International trial of the Edmonton protocol for islet transplantation. N Engl J Med. 2006;355:1318-30.
-
(2006)
N Engl J Med
, vol.355
, pp. 1318-1330
-
-
Shapiro, A.M.1
Ricordi, C.2
Hering, B.J.3
Auchincloss, H.4
Lindblad, R.5
Robertson, R.P.6
Secchi, A.7
Brendel, M.D.8
Berney, T.9
Brennan, D.C.10
Cagliero, E.11
Alejandro, R.12
Ryan, E.A.13
DiMercurio, B.14
Morel, P.15
Polonsky, K.S.16
Reems, J.A.17
Bretzel, R.G.18
Bertuzzi, F.19
Froud, T.20
Kandaswamy, R.21
Sutherland, D.E.22
Eisenbarth, G.23
Segal, M.24
Preiksaitis, J.25
Korbutt, G.S.26
Barton, F.B.27
Viviano, L.28
Seyfert-Margolis, V.29
Bluestone, J.30
Lakey, J.R.31
more..
-
8
-
-
49549102057
-
Mesenchymal stem cells: Biology and clinical potential in type 1 diabetes therapy
-
Epub Feb 24
-
Liu M, Han ZC. Mesenchymal stem cells: biology and clinical potential in type 1 diabetes therapy. J Cell Mol Med. 2008;12:1155-68. Epub 2008 Feb 24.
-
(2008)
J Cell Mol Med. 2008
, vol.12
, pp. 1155-1168
-
-
Liu, M.1
Han, Z.C.2
-
9
-
-
0033001488
-
The NOD mouse model of type 1 diabetes: As good as it gets?
-
Atkinson MA, Leiter EH. The NOD mouse model of type 1 diabetes: as good as it gets? Nat Med. 1999;5:601-4.
-
(1999)
Nat Med
, vol.5
, pp. 601-604
-
-
Atkinson, M.A.1
Leiter, E.H.2
-
10
-
-
17644361955
-
The NOD mouse: A model of immune dysregulation
-
Anderson MS, Bluestone JA. The NOD mouse: a model of immune dysregulation. Annu Rev Immunol. 2005;23:447-85.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 447-485
-
-
Anderson, M.S.1
Bluestone, J.A.2
-
11
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol. 1989;7:145-73.
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
12
-
-
0242416575
-
Cytokines and transcription factors that regulate T helper cell differentiation: New players and new insights
-
Agnello D, Lankford CS, Bream J, Morinobu A, Gadina M, O'Shea JJ, Frucht DM. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol. 2003;23:147-61.
-
(2003)
J Clin Immunol
, vol.23
, pp. 147-161
-
-
Agnello, D.1
Lankford, C.S.2
Bream, J.3
Morinobu, A.4
Gadina, M.5
O'Shea, J.J.6
Frucht, D.M.7
-
13
-
-
9644262463
-
Signaling pathways in Th2 development
-
Mowen KA, Glimcher LH. Signaling pathways in Th2 development. Immunol Rev. 2004;202:203-22.
-
(2004)
Immunol Rev
, vol.202
, pp. 203-222
-
-
Mowen, K.A.1
Glimcher, L.H.2
-
14
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol. 2005;6:1133-41.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
15
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005;6:1123-32.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
16
-
-
33744984785
-
Th17: An effector CD4 T cell lineage with regulatory T cell ties
-
Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Murphy KM. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity. 2006;24:677-88.
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
17
-
-
34247555353
-
Differentiation and function of Th17 T cells
-
Stockinger B, Veldhoen M. Differentiation and function of Th17 T cells. Curr Opin Immunol. 2007;19:281-6.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 281-286
-
-
Stockinger, B.1
Veldhoen, M.2
-
18
-
-
35348960243
-
Th17: The third member of the effector T cell trilogy
-
Bettelli E, Korn T, Kuchroo VK. Th17: the third member of the effector T cell trilogy. Curr Opin Immunol. 2007;19:652-7.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 652-657
-
-
Bettelli, E.1
Korn, T.2
Kuchroo, V.K.3
-
19
-
-
41549134361
-
Th17 cell differentiation: The long and winding road
-
McGeachy MJ, Cua DJ. Th17 cell differentiation: the long and winding road. Immunity. 2008;28:445-53.
-
(2008)
Immunity
, vol.28
, pp. 445-453
-
-
McGeachy, M.J.1
Cua, D.J.2
-
20
-
-
41549135632
-
The biological functions of T helper 17 cell effector cytokines in inflammation
-
Ouyang W, Kolls JK, Zheng Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity. 2008;28:454-67.
-
(2008)
Immunity
, vol.28
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
21
-
-
42649115767
-
TH17 cells in development: An updated view of their molecular identity and genetic programming
-
Dong C. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat Rev Immunol. 2008;8:337-48.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 337-348
-
-
Dong, C.1
-
22
-
-
35548994594
-
Recent advancement of understanding pathogenesis of type 1 diabetes and potential relevance to diabetic nephropathy
-
Ichinose K, Kawasaki E, Eguchi K. Recent advancement of understanding pathogenesis of type 1 diabetes and potential relevance to diabetic nephropathy. Am J Nephrol. 2007;27:554-64.
-
(2007)
Am J Nephrol
, vol.27
, pp. 554-564
-
-
Ichinose, K.1
Kawasaki, E.2
Eguchi, K.3
-
23
-
-
85056045610
-
Imbalance in Th cell polarization and its relevance in type 1 diabetes mellitus
-
Sia C. Imbalance in Th cell polarization and its relevance in type 1 diabetes mellitus. Rev Diabet Stud. 2005;2:182-6.
-
(2005)
Rev Diabet Stud
, vol.2
, pp. 182-186
-
-
Sia, C.1
-
24
-
-
0037094032
-
Molecular mechanisms for gender differences in susceptibility to T cell-mediated autoimmune diabetes in nonobese diabetic mice
-
Bao M, Yang Y, Jun HS, Yoon JW. Molecular mechanisms for gender differences in susceptibility to T cell-mediated autoimmune diabetes in nonobese diabetic mice. J Immunol. 2002;168:5369-75.
-
(2002)
J Immunol
, vol.168
, pp. 5369-5375
-
-
Bao, M.1
Yang, Y.2
Jun, H.S.3
Yoon, J.W.4
-
25
-
-
30944455075
-
IL-23 leads to diabetes induction after subdiabetogenic treatment with multiple low doses of streptozotocin
-
Mensah-Brown EP, Shahin A, Al-Shamisi M, Wei X, Lukic ML. IL-23 leads to diabetes induction after subdiabetogenic treatment with multiple low doses of streptozotocin. Eur J Immunol. 2006;36:216-23.
-
(2006)
Eur J Immunol
, vol.36
, pp. 216-223
-
-
Mensah-Brown, E.P.1
Shahin, A.2
Al-Shamisi, M.3
Wei, X.4
Lukic, M.L.5
-
26
-
-
28344439845
-
Interleukin-17 stimulates inducible nitric oxide synthase-dependent toxicity in mouse beta cells
-
Miljkovic D, Cvetkovic I, Momcilovic M, Maksimovic-Ivanic D, Stosic-Grujicic S, Trajkovic V. Interleukin-17 stimulates inducible nitric oxide synthase-dependent toxicity in mouse beta cells. Cell Mol Life Sci. 2005;62:2658-68.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 2658-2668
-
-
Miljkovic, D.1
Cvetkovic, I.2
Momcilovic, M.3
Maksimovic-Ivanic, D.4
Stosic-Grujicic, S.5
Trajkovic, V.6
-
27
-
-
0035061536
-
Tolerance to islet autoantigens in type 1 diabetes
-
Bach JF, Chatenoud L. Tolerance to islet autoantigens in type 1 diabetes. Annu Rev Immunol. 2001;19:131-61.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 131-161
-
-
Bach, J.F.1
Chatenoud, L.2
-
28
-
-
34548361965
-
Roles of cytokines in the pathogenesis and therapy of type 1 diabetes
-
Rabinovitch A, Suarez-Pinzon WL. Roles of cytokines in the pathogenesis and therapy of type 1 diabetes. Cell Biochem Biophys. 2007;48:159-63.
-
(2007)
Cell Biochem Biophys
, vol.48
, pp. 159-163
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
-
29
-
-
0031573072
-
IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function
-
Cameron MJ, Arreaza GA, Zucker P, Chensue SW, Strieter RM, Chakrabarti S, Delovitch TL. IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function. J Immunol. 1997;159:4686-92.
-
(1997)
J Immunol
, vol.159
, pp. 4686-4692
-
-
Cameron, M.J.1
Arreaza, G.A.2
Zucker, P.3
Chensue, S.W.4
Strieter, R.M.5
Chakrabarti, S.6
Delovitch, T.L.7
-
30
-
-
0033179229
-
Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse
-
Gallichan WS, Balasa B, Davies JD, Sarvetnick N. Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse. J Immunol. 1999;163:1696-703.
-
(1999)
J Immunol
, vol.163
, pp. 1696-1703
-
-
Gallichan, W.S.1
Balasa, B.2
Davies, J.D.3
Sarvetnick, N.4
-
31
-
-
0029838995
-
Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice
-
Mueller R, Krahl T, Sarvetnick N. Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med. 1996;184:1093-9.
-
(1996)
J Exp Med
, vol.184
, pp. 1093-1099
-
-
Mueller, R.1
Krahl, T.2
Sarvetnick, N.3
-
32
-
-
0027272228
-
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice
-
Rapoport MJ, Jaramillo A, Zipris D, Lazarus AH, Serreze DV, Leiter EH, Cyopick P, Danska JS, Delovitch TL. Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice. J Exp Med. 1993;178:87-99.
-
(1993)
J Exp Med
, vol.178
, pp. 87-99
-
-
Rapoport, M.J.1
Jaramillo, A.2
Zipris, D.3
Lazarus, A.H.4
Serreze, D.V.5
Leiter, E.H.6
Cyopick, P.7
Danska, J.S.8
Delovitch, T.L.9
-
33
-
-
0036198813
-
Prevention of autoimmune insulitis by delivery of interleukin-4 plasmid using a soluble and bio-degradable polymeric carrier
-
Lee M, Koh JJ, Han SO, Ko KS, Ki SW. Prevention of autoimmune insulitis by delivery of interleukin-4 plasmid using a soluble and bio-degradable polymeric carrier. Pharm Res. 2002;19:246-9.
-
(2002)
Pharm Res
, vol.19
, pp. 246-249
-
-
Lee, M.1
Koh, J.J.2
Han, S.O.3
Ko, K.S.4
Ki, S.W.5
-
34
-
-
0035871805
-
The activity of immunoregulatory T cells mediating active tolerance is potentiated in nonobese diabetic mice by an IL-4-based retroviral gene therapy
-
Yamamoto AM, Chernajovsky Y, Lepault F, Podhajcer O, Feldmann M, Bach JF, Chatenoud L. The activity of immunoregulatory T cells mediating active tolerance is potentiated in nonobese diabetic mice by an IL-4-based retroviral gene therapy. J Immunol. 2001;166:4973-80.
-
(2001)
J Immunol
, vol.166
, pp. 4973-4980
-
-
Yamamoto, A.M.1
Chernajovsky, Y.2
Lepault, F.3
Podhajcer, O.4
Feldmann, M.5
Bach, J.F.6
Chatenoud, L.7
-
35
-
-
0033721160
-
Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer
-
Cameron MJ, Arreaza GA, Waldhauser L, Gauldie J, Delovitch TL. Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer. Gene Ther. 2000;7:1840-6.
-
(2000)
Gene Ther
, vol.7
, pp. 1840-1846
-
-
Cameron, M.J.1
Arreaza, G.A.2
Waldhauser, L.3
Gauldie, J.4
Delovitch, T.L.5
-
36
-
-
0034632361
-
Biolistic-mediated interleukin 4 gene transfer prevents the onset of type 1 diabetes
-
Cameron MJ, Strathdee CA, Holmes KD, Arreaza GA, Dekaban GA, Delovitch TL. Biolistic-mediated interleukin 4 gene transfer prevents the onset of type 1 diabetes. Hum Gene Ther. 2000;11:1647-56.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1647-1656
-
-
Cameron, M.J.1
Strathdee, C.A.2
Holmes, K.D.3
Arreaza, G.A.4
Dekaban, G.A.5
Delovitch, T.L.6
-
37
-
-
0036584901
-
A single treatment with IL-4 via retrovirally transduced lymphocytes partially protects against diabetes in BioBreeding (BB) rats. JOP
-
Zipris D, Karnieli E. A single treatment with IL-4 via retrovirally transduced lymphocytes partially protects against diabetes in BioBreeding (BB) rats. JOP. 2002;3:76-82.
-
(2002)
, vol.3
, pp. 76-82
-
-
Zipris, D.1
Karnieli, E.2
-
38
-
-
0037248946
-
Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis
-
Feili-Hariri M, Falkner DH, Gambotto A, Papworth GD, Watkins SC, Robbins PD, Morel PA. Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis. Hum Gene Ther. 2003;14:13-23.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 13-23
-
-
Feili-Hariri, M.1
Falkner, D.H.2
Gambotto, A.3
Papworth, G.D.4
Watkins, S.C.5
Robbins, P.D.6
Morel, P.A.7
-
39
-
-
41549150638
-
Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice
-
Creusot RJ, Yaghoubi SS, Kodama K, Dang DN, Dang VH, Breckpot K, Thielemans K, Gambhir SS, Fathman CG. Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice. Clin Immunol. 2008;127:176-87.
-
(2008)
Clin Immunol
, vol.127
, pp. 176-187
-
-
Creusot, R.J.1
Yaghoubi, S.S.2
Kodama, K.3
Dang, D.N.4
Dang, V.H.5
Breckpot, K.6
Thielemans, K.7
Gambhir, S.S.8
Fathman, C.G.9
-
40
-
-
0037899021
-
-
Hayashi T, Yasutomi Y, Hasegawa K, Sasaki Y, Onodera T. Interleukin-4-expressing plasmid DNA inhibits reovirus type-2-triggered autoimmune insulitis in DBA/1 J suckling mice. Int J Exp Pathol. 2003;84:101-6.
-
Hayashi T, Yasutomi Y, Hasegawa K, Sasaki Y, Onodera T. Interleukin-4-expressing plasmid DNA inhibits reovirus type-2-triggered autoimmune insulitis in DBA/1 J suckling mice. Int J Exp Pathol. 2003;84:101-6.
-
-
-
-
41
-
-
0037347652
-
High-level expression of interleukin-4 following electroporation-mediated gene transfer accelerates type 1 diabetes in NOD mice
-
Horiki M, Yamato E, Noso S, Ikegami H, Ogihara T, Miyazaki J. High-level expression of interleukin-4 following electroporation-mediated gene transfer accelerates type 1 diabetes in NOD mice. J Autoimmun. 2003;20:111-7.
-
(2003)
J Autoimmun
, vol.20
, pp. 111-117
-
-
Horiki, M.1
Yamato, E.2
Noso, S.3
Ikegami, H.4
Ogihara, T.5
Miyazaki, J.6
-
42
-
-
1842864843
-
A murine interleukin-4-Ig fusion protein regulates the expression of Th1- and Th2-specific cytokines in the pancreas of NOD mice
-
Walz M, Overbergh L, Mathieu C, Kolb H, Martin S. A murine interleukin-4-Ig fusion protein regulates the expression of Th1- and Th2-specific cytokines in the pancreas of NOD mice. Horm Metab Res. 2002;34:561-9.
-
(2002)
Horm Metab Res
, vol.34
, pp. 561-569
-
-
Walz, M.1
Overbergh, L.2
Mathieu, C.3
Kolb, H.4
Martin, S.5
-
43
-
-
0030879734
-
Mechanism underlying counterregulation of autoimmune diabetes by IL-4
-
Mueller R, Bradley LM, Krahl T, Sarvetnick N. Mechanism underlying counterregulation of autoimmune diabetes by IL-4. Immunity. 1997;7:411-8.
-
(1997)
Immunity
, vol.7
, pp. 411-418
-
-
Mueller, R.1
Bradley, L.M.2
Krahl, T.3
Sarvetnick, N.4
-
44
-
-
0035122538
-
Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses
-
King C, Mueller Hoenger R, Malo Cleary M, Murali-Krishna K, Ahmed R, King E, Sarvetnick N. Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses. Nat Med. 2001;7:206-14.
-
(2001)
Nat Med
, vol.7
, pp. 206-214
-
-
King, C.1
Mueller Hoenger, R.2
Malo Cleary, M.3
Murali-Krishna, K.4
Ahmed, R.5
King, E.6
Sarvetnick, N.7
-
45
-
-
0031571310
-
IL-4 expression by grafts from transgenic mice fails to prevent allograft rejection
-
Mueller R, Davies JD, Krahl T, Sarvetnick N. IL-4 expression by grafts from transgenic mice fails to prevent allograft rejection. J Immunol. 1997;159:1599-603.
-
(1997)
J Immunol
, vol.159
, pp. 1599-1603
-
-
Mueller, R.1
Davies, J.D.2
Krahl, T.3
Sarvetnick, N.4
-
46
-
-
0030773969
-
Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice
-
Smith DK, Korbutt GS, Suarez-Pinzon WL, Kao D, Rajotte RV, Elliott JF. Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice. Transplantation. 1997;64:1040-9.
-
(1997)
Transplantation
, vol.64
, pp. 1040-1049
-
-
Smith, D.K.1
Korbutt, G.S.2
Suarez-Pinzon, W.L.3
Kao, D.4
Rajotte, R.V.5
Elliott, J.F.6
-
47
-
-
44449096726
-
IL-10: The master regulator of immunity to infection
-
Couper KN, Blount DG, Riley EM. IL-10: the master regulator of immunity to infection. J Immunol. 2008;180:5771-7.
-
(2008)
J Immunol
, vol.180
, pp. 5771-5777
-
-
Couper, K.N.1
Blount, D.G.2
Riley, E.M.3
-
48
-
-
22644438152
-
Viral IL-10-mediated immune regulation in pancreatic islet transplantation
-
Carter JD, Ellett JD, Chen M, Smith KM, Fialkow LB, McDuffie MJ, Tung KS, Nadler JL, Yang Z. Viral IL-10-mediated immune regulation in pancreatic islet transplantation. Mol Ther. 2005;12:360-8.
-
(2005)
Mol Ther
, vol.12
, pp. 360-368
-
-
Carter, J.D.1
Ellett, J.D.2
Chen, M.3
Smith, K.M.4
Fialkow, L.B.5
McDuffie, M.J.6
Tung, K.S.7
Nadler, J.L.8
Yang, Z.9
-
49
-
-
0042931258
-
Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion
-
Goudy KS, Burkhardt BR, Wasserfall C, Song S, Campbell-Thompson ML, Brusko T, Powers MA, Clare-Salzler MJ, Sobel ES, Ellis TM, Flotte TR, Atkinson MA. Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion. J Immunol. 2003;171:2270-8.
-
(2003)
J Immunol
, vol.171
, pp. 2270-2278
-
-
Goudy, K.S.1
Burkhardt, B.R.2
Wasserfall, C.3
Song, S.4
Campbell-Thompson, M.L.5
Brusko, T.6
Powers, M.A.7
Clare-Salzler, M.J.8
Sobel, E.S.9
Ellis, T.M.10
Flotte, T.R.11
Atkinson, M.A.12
-
50
-
-
0344642932
-
Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice
-
Zhang YC, Pileggi A, Agarwal A, Molano RD, Powers M, Brusko T, Wasserfall C, Goudy K, Zahr E, Poggioli R, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick H, Flotte T, Ellis TM, Ricordi C, Inverardi L, Atkinson MA. Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice. Diabetes. 2003;52:708-16.
-
(2003)
Diabetes
, vol.52
, pp. 708-716
-
-
Zhang, Y.C.1
Pileggi, A.2
Agarwal, A.3
Molano, R.D.4
Powers, M.5
Brusko, T.6
Wasserfall, C.7
Goudy, K.8
Zahr, E.9
Poggioli, R.10
Scott-Jorgensen, M.11
Campbell-Thompson, M.12
Crawford, J.M.13
Nick, H.14
Flotte, T.15
Ellis, T.M.16
Ricordi, C.17
Inverardi, L.18
Atkinson, M.A.19
-
51
-
-
0035923680
-
Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice
-
Goudy K, Song S, Wasserfall C, Zhang YC, Kapturczak M, Muir A, Powers M, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Ellis TM, Flotte TR, Atkinson MA. Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice. Proc Natl Acad Sci U S A. 2001;98:13913-8.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13913-13918
-
-
Goudy, K.1
Song, S.2
Wasserfall, C.3
Zhang, Y.C.4
Kapturczak, M.5
Muir, A.6
Powers, M.7
Scott-Jorgensen, M.8
Campbell-Thompson, M.9
Crawford, J.M.10
Ellis, T.M.11
Flotte, T.R.12
Atkinson, M.A.13
-
52
-
-
0032504602
-
Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice
-
Nitta Y, Tashiro F, Tokui M, Shimada A, Takei I, Tabayashi K, Miyazaki J. Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice. Hum Gene Ther. 1998;9:1701-7.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1701-1707
-
-
Nitta, Y.1
Tashiro, F.2
Tokui, M.3
Shimada, A.4
Takei, I.5
Tabayashi, K.6
Miyazaki, J.7
-
53
-
-
0037097550
-
Suppression of autoimmune diabetes by viral IL-10 gene transfer
-
Yang Z, Chen M, Wu R, Fialkow LB, Bromberg JS, McDuffie M, Naji A, Nadler JL. Suppression of autoimmune diabetes by viral IL-10 gene transfer. J Immunol. 2002;168:6479-85.
-
(2002)
J Immunol
, vol.168
, pp. 6479-6485
-
-
Yang, Z.1
Chen, M.2
Wu, R.3
Fialkow, L.B.4
Bromberg, J.S.5
McDuffie, M.6
Naji, A.7
Nadler, J.L.8
-
54
-
-
0034504234
-
Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice
-
Koh JJ, Ko KS, Lee M, Han S, Park JS, Kim SW. Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice. Gene Ther. 2000;7:2099-104.
-
(2000)
Gene Ther
, vol.7
, pp. 2099-2104
-
-
Koh, J.J.1
Ko, K.S.2
Lee, M.3
Han, S.4
Park, J.S.5
Kim, S.W.6
-
55
-
-
33845709923
-
Interleukin-10 plasmid construction and delivery for the prevention of type 1 diabetes
-
Lee M, Park H, Youn J, Oh ET, Ko K, Kim S, Park Y. Interleukin-10 plasmid construction and delivery for the prevention of type 1 diabetes. Ann N Y Acad Sci. 2006;1079:313-9.
-
(2006)
Ann N Y Acad Sci
, vol.1079
, pp. 313-319
-
-
Lee, M.1
Park, H.2
Youn, J.3
Oh, E.T.4
Ko, K.5
Kim, S.6
Park, Y.7
-
56
-
-
0034760333
-
Combined administration of plasmids encoding IL-4 and IL-10 prevents the development of autoimmune diabetes in nonobese diabetic mice
-
Ko KS, Lee M, Koh JJ, Kim SW. Combined administration of plasmids encoding IL-4 and IL-10 prevents the development of autoimmune diabetes in nonobese diabetic mice. Mol Ther. 2001;4:313-6.
-
(2001)
Mol Ther
, vol.4
, pp. 313-316
-
-
Ko, K.S.1
Lee, M.2
Koh, J.J.3
Kim, S.W.4
-
57
-
-
0042404129
-
Intramuscular injection of interleukin-10 plasmid DNA prevented autoimmune diabetes in mice
-
Zhang ZL, Shen SX, Lin B, Yu LY, Zhu LH, Wang WP, Luo FH, Guo LH. Intramuscular injection of interleukin-10 plasmid DNA prevented autoimmune diabetes in mice. Acta Pharmacol Sin. 2003;24:751-6.
-
(2003)
Acta Pharmacol Sin
, vol.24
, pp. 751-756
-
-
Zhang, Z.L.1
Shen, S.X.2
Lin, B.3
Yu, L.Y.4
Zhu, L.H.5
Wang, W.P.6
Luo, F.H.7
Guo, L.H.8
-
58
-
-
23944489798
-
Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice
-
Zhang YC, Pileggi A, Molano RD, Wasserfall C, Campbell-Thompson M, Ricordi C, Atkinson MA, Inverardi L. Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice. Transplantation. 2005;80:530-3.
-
(2005)
Transplantation
, vol.80
, pp. 530-533
-
-
Zhang, Y.C.1
Pileggi, A.2
Molano, R.D.3
Wasserfall, C.4
Campbell-Thompson, M.5
Ricordi, C.6
Atkinson, M.A.7
Inverardi, L.8
-
59
-
-
34548156165
-
Ex vivo gene transfer of viral interleukin-10 to BB rat islets: No protection after transplantation to diabetic BB rats
-
Kuttler B, Wanka H, Kloting N, Gerstmayer B, Volk HD, Sawitzki B, Ritter T. Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats. J Cell Mol Med. 2007;11:868-80.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 868-880
-
-
Kuttler, B.1
Wanka, H.2
Kloting, N.3
Gerstmayer, B.4
Volk, H.D.5
Sawitzki, B.6
Ritter, T.7
-
60
-
-
27544513432
-
Interleukin-10 gene transfection of donor pancreas grafts protects against rejection after heterotopic pancreas transplantation in a rat model
-
Ozden H, Kabay B, Guven G, Acikalin MF, Erbis H, Alatas O. Interleukin-10 gene transfection of donor pancreas grafts protects against rejection after heterotopic pancreas transplantation in a rat model. Eur Surg Res. 2005;37:220-7.
-
(2005)
Eur Surg Res
, vol.37
, pp. 220-227
-
-
Ozden, H.1
Kabay, B.2
Guven, G.3
Acikalin, M.F.4
Erbis, H.5
Alatas, O.6
-
61
-
-
34249678653
-
TGFbeta signalling in control of T-cell-mediated self-reactivity
-
Rubtsov YP, Rudensky AY. TGFbeta signalling in control of T-cell-mediated self-reactivity. Nat Rev Immunol. 2007;7:443-53.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 443-453
-
-
Rubtsov, Y.P.1
Rudensky, A.Y.2
-
62
-
-
0032531423
-
TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice
-
Piccirillo CA, Chang Y, Prud'homme GJ. TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice. J Immunol. 1998;161:3950-6.
-
(1998)
J Immunol
, vol.161
, pp. 3950-3956
-
-
Piccirillo, C.A.1
Chang, Y.2
Prud'homme, G.J.3
-
63
-
-
20844446146
-
Systemic transforming growth factor-beta1 gene therapy induces Foxp3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice
-
Luo X, Yang H, Kim IS, Saint-Hilaire F, Thomas DA, De BP, Ozkaynak E, Muthukumar T, Hancock WW, Crystal RG, Suthanthiran M. Systemic transforming growth factor-beta1 gene therapy induces Foxp3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice. Transplantation. 2005;79:1091-6.
-
(2005)
Transplantation
, vol.79
, pp. 1091-1096
-
-
Luo, X.1
Yang, H.2
Kim, I.S.3
Saint-Hilaire, F.4
Thomas, D.A.5
De, B.P.6
Ozkaynak, E.7
Muthukumar, T.8
Hancock, W.W.9
Crystal, R.G.10
Suthanthiran, M.11
-
64
-
-
0036408818
-
Gene transfection and expression of transforming growth factor-beta1 in nonobese diabetic mouse islets protects betacells in syngeneic islet grafts from autoimmune destruction
-
Suarez-Pinzon WL, Marcoux Y, Ghahary A, Rabinovitch A. Gene transfection and expression of transforming growth factor-beta1 in nonobese diabetic mouse islets protects betacells in syngeneic islet grafts from autoimmune destruction. Cell Transplant. 2002;11:519-28.
-
(2002)
Cell Transplant
, vol.11
, pp. 519-528
-
-
Suarez-Pinzon, W.L.1
Marcoux, Y.2
Ghahary, A.3
Rabinovitch, A.4
-
65
-
-
43049167388
-
Prevention of recurrent but not spontaneous autoimmune diabetes by transplanted NOD islets adenovirally transduced with immunomodulating molecules
-
Sakata M, Yasuda H, Moriyama H, Yamada K, Kotani R, Kurohara M, Okumachi Y, Kishi M, Arai T, Hara K, Hamada H, Yokono K, Nagata M. Prevention of recurrent but not spontaneous autoimmune diabetes by transplanted NOD islets adenovirally transduced with immunomodulating molecules. Diabetes Res Clin Pract. 2008;80:352-9.
-
(2008)
Diabetes Res Clin Pract
, vol.80
, pp. 352-359
-
-
Sakata, M.1
Yasuda, H.2
Moriyama, H.3
Yamada, K.4
Kotani, R.5
Kurohara, M.6
Okumachi, Y.7
Kishi, M.8
Arai, T.9
Hara, K.10
Hamada, H.11
Yokono, K.12
Nagata, M.13
-
66
-
-
38749111445
-
Innocuous IFN gamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production
-
Jain R, Tartar DM, Gregg RK, Divekar RD, Bell JJ, Lee HH, Yu P, Ellis JS, Hoeman CM, Franklin CL, Zaghouani H. Innocuous IFN gamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production. J Exp Med. 2008;205:207-18.
-
(2008)
J Exp Med
, vol.205
, pp. 207-218
-
-
Jain, R.1
Tartar, D.M.2
Gregg, R.K.3
Divekar, R.D.4
Bell, J.J.5
Lee, H.H.6
Yu, P.7
Ellis, J.S.8
Hoeman, C.M.9
Franklin, C.L.10
Zaghouani, H.11
-
67
-
-
7844230594
-
Local expression of immunoregulatory IL-12p40 gene prolonged syngeneic islet graft survival in diabetic NOD mice
-
Yasuda H, Nagata M, Arisawa K, Yoshida R, Fujihira K, Okamoto N, Moriyama H, Miki M, Saito I, Hamada H, Yokono K, Kasuga M. Local expression of immunoregulatory IL-12p40 gene prolonged syngeneic islet graft survival in diabetic NOD mice. J Clin Invest. 1998;102:1807-14.
-
(1998)
J Clin Invest
, vol.102
, pp. 1807-1814
-
-
Yasuda, H.1
Nagata, M.2
Arisawa, K.3
Yoshida, R.4
Fujihira, K.5
Okamoto, N.6
Moriyama, H.7
Miki, M.8
Saito, I.9
Hamada, H.10
Yokono, K.11
Kasuga, M.12
-
68
-
-
46749117207
-
Determination of T-cell fate by dendritic cells
-
Epub Apr 1
-
Diebold SS. Determination of T-cell fate by dendritic cells. Immunol Cell Biol. 2008;86:389-97. Epub 2008 Apr 1.
-
(2008)
Immunol Cell Biol. 2008
, vol.86
, pp. 389-397
-
-
Diebold, S.S.1
-
70
-
-
0033939942
-
Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo
-
Lutz MB, Suri RM, Niimi M, Ogilvie AL, Kukutsch NA, Rossner S, Schuler G, Austyn JM. Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo. Eur J Immunol. 2000;30:1813-22.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1813-1822
-
-
Lutz, M.B.1
Suri, R.M.2
Niimi, M.3
Ogilvie, A.L.4
Kukutsch, N.A.5
Rossner, S.6
Schuler, G.7
Austyn, J.M.8
-
71
-
-
0036145202
-
Granulocyte macrophagecolony stimulating factor (GM-CSF) recruits immune cells to the pancreas and delays STZ-induced diabetes
-
Krakowski M, Abdelmalik R, Mocnik L, Krahl T, Sarvetnick N. Granulocyte macrophagecolony stimulating factor (GM-CSF) recruits immune cells to the pancreas and delays STZ-induced diabetes. J Pathol. 2002;196:103-12.
-
(2002)
J Pathol
, vol.196
, pp. 103-112
-
-
Krakowski, M.1
Abdelmalik, R.2
Mocnik, L.3
Krahl, T.4
Sarvetnick, N.5
-
72
-
-
35748929090
-
Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells
-
Gaudreau S, Guindi C, Menard M, Besin G, Dupuis G, Amrani A. Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells. J Immunol. 2007;179:3638-47.
-
(2007)
J Immunol
, vol.179
, pp. 3638-3647
-
-
Gaudreau, S.1
Guindi, C.2
Menard, M.3
Besin, G.4
Dupuis, G.5
Amrani, A.6
-
73
-
-
0033011514
-
Transfer of dendritic cells (DC) ex vivo stimulated with interferon-gamma (IFN-gamma) down-modulates autoimmune diabetes in non-obese diabetic (NOD) mice
-
Shinomiya M, Fazle Akbar SM, Shinomiya H, Onji M. Transfer of dendritic cells (DC) ex vivo stimulated with interferon-gamma (IFN-gamma) down-modulates autoimmune diabetes in non-obese diabetic (NOD) mice. Clin Exp Immunol. 1999;117:38-43.
-
(1999)
Clin Exp Immunol
, vol.117
, pp. 38-43
-
-
Shinomiya, M.1
Fazle Akbar, S.M.2
Shinomiya, H.3
Onji, M.4
-
74
-
-
0031725364
-
Epitope dominance: Evidence for reciprocal determinant spreading to glutamic acid decarboxylase in nonobese diabetic mice
-
Zechel MA, Krawetz MD, Singh B. Epitope dominance: evidence for reciprocal determinant spreading to glutamic acid decarboxylase in nonobese diabetic mice. Immunol Rev. 1998;164:111-8.
-
(1998)
Immunol Rev
, vol.164
, pp. 111-118
-
-
Zechel, M.A.1
Krawetz, M.D.2
Singh, B.3
-
75
-
-
0031452948
-
Determinant spreading of T helper cell 2 (Th2) responses to pancreatic islet autoantigens
-
Tian J, Lehmann PV, Kaufman DL. Determinant spreading of T helper cell 2 (Th2) responses to pancreatic islet autoantigens. J Exp Med. 1997;186:2039-43.
-
(1997)
J Exp Med
, vol.186
, pp. 2039-2043
-
-
Tian, J.1
Lehmann, P.V.2
Kaufman, D.L.3
-
76
-
-
0035876930
-
The frequency of high avidity T cells determines the hierarchy of determinant spreading
-
Tian J, Gregori S, Adorini L, Kaufman DL. The frequency of high avidity T cells determines the hierarchy of determinant spreading. J Immunol. 2001;166:7144-50.
-
(2001)
J Immunol
, vol.166
, pp. 7144-7150
-
-
Tian, J.1
Gregori, S.2
Adorini, L.3
Kaufman, D.L.4
-
77
-
-
16244396427
-
The stages of type 1A diabetes: 2005
-
Gianani R, Eisenbarth GS. The stages of type 1A diabetes: 2005. Immunol Rev. 2005;204:232-49.
-
(2005)
Immunol Rev
, vol.204
, pp. 232-249
-
-
Gianani, R.1
Eisenbarth, G.S.2
-
78
-
-
33847629171
-
Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes
-
Di Lorenzo TP, Peakman M, Roep BO. Translational mini-review series on type 1 diabetes: systematic analysis of T cell epitopes in autoimmune diabetes. Clin Exp Immunol. 2007;148:1-16.
-
(2007)
Clin Exp Immunol
, vol.148
, pp. 1-16
-
-
Di Lorenzo, T.P.1
Peakman, M.2
Roep, B.O.3
-
79
-
-
0035867792
-
Vaccination with glutamic acid decarboxylase plasmid DNA protects mice from spontaneous autoimmune diabetes and B7/CD28 costimulation circumvents that protection
-
Balasa B, Boehm BO, Fortnagel A, Karges W, Van Gunst K, Jung N, Camacho SA, Webb SR, Sarvetnick N. Vaccination with glutamic acid decarboxylase plasmid DNA protects mice from spontaneous autoimmune diabetes and B7/CD28 costimulation circumvents that protection. Clin Immunol. 2001;99:241-52.
-
(2001)
Clin Immunol
, vol.99
, pp. 241-252
-
-
Balasa, B.1
Boehm, B.O.2
Fortnagel, A.3
Karges, W.4
Van Gunst, K.5
Jung, N.6
Camacho, S.A.7
Webb, S.R.8
Sarvetnick, N.9
-
80
-
-
0035573750
-
Effects of plasmid DNA injection on cyclophosphamide-accelerated diabetes in NOD mice
-
Filippova M, Liu J, Escher A. Effects of plasmid DNA injection on cyclophosphamide-accelerated diabetes in NOD mice. DNA Cell Biol. 2001;20:175-81.
-
(2001)
DNA Cell Biol
, vol.20
, pp. 175-181
-
-
Filippova, M.1
Liu, J.2
Escher, A.3
-
81
-
-
0035985085
-
Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase
-
Jun HS, Chung YH, Han J, Kim A, Yoo SS, Sherwin RS, Yoon JW. Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase. Diabetologia. 2002;45:668-76.
-
(2002)
Diabetologia
, vol.45
, pp. 668-676
-
-
Jun, H.S.1
Chung, Y.H.2
Han, J.3
Kim, A.4
Yoo, S.S.5
Sherwin, R.S.6
Yoon, J.W.7
-
82
-
-
0035253510
-
Antigen-specific mediated suppression of beta cell autoimmunity by plasmid DNA vaccination
-
Tisch R, Wang B, Weaver DJ, Liu B, Bui T, Arthos J, Serreze DV. Antigen-specific mediated suppression of beta cell autoimmunity by plasmid DNA vaccination. J Immunol. 2001;166:2122-32.
-
(2001)
J Immunol
, vol.166
, pp. 2122-2132
-
-
Tisch, R.1
Wang, B.2
Weaver, D.J.3
Liu, B.4
Bui, T.5
Arthos, J.6
Serreze, D.V.7
-
83
-
-
0035451681
-
Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice
-
Bot A, Smith D, Bot S, Hughes A, Wolfe T, Wang L, Woods C, von Herrath M. Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice. J Immunol. 2001;167:2950-5.
-
(2001)
J Immunol
, vol.167
, pp. 2950-2955
-
-
Bot, A.1
Smith, D.2
Bot, S.3
Hughes, A.4
Wolfe, T.5
Wang, L.6
Woods, C.7
von Herrath, M.8
-
84
-
-
0035399816
-
Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice
-
Weaver DJ Jr, Liu B, Tisch R. Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice. J Immunol. 2001;167:586-92.
-
(2001)
J Immunol
, vol.167
, pp. 586-592
-
-
Weaver Jr, D.J.1
Liu, B.2
Tisch, R.3
-
85
-
-
20144388199
-
Active tolerance induction and prevention of autoimmune diabetes by immunogene therapy using recombinant adenoassociated virus expressing glutamic acid decarboxylase 65 peptide GAD (500-585)
-
Han G, Li Y, Wang J, Wang R, Chen G, Song L, Xu R, Yu M, Wu X, Qian J, Shen B. Active tolerance induction and prevention of autoimmune diabetes by immunogene therapy using recombinant adenoassociated virus expressing glutamic acid decarboxylase 65 peptide GAD (500-585). J Immunol. 2005;174:4516-24.
-
(2005)
J Immunol
, vol.174
, pp. 4516-4524
-
-
Han, G.1
Li, Y.2
Wang, J.3
Wang, R.4
Chen, G.5
Song, L.6
Xu, R.7
Yu, M.8
Wu, X.9
Qian, J.10
Shen, B.11
-
86
-
-
37749038350
-
Gene delivery GAD 500 autoantigen by AAV serotype 1 prevented diabetes in NOD mice: Transduction efficiency do not play important roles
-
Han G, Wang R, Chen G, Wang J, Xu R, Feng J, Yu M, Wu X, Qian J, Shen B, Li Y. Gene delivery GAD 500 autoantigen by AAV serotype 1 prevented diabetes in NOD mice: transduction efficiency do not play important roles. Immunol Lett. 2008;115:110-6.
-
(2008)
Immunol Lett
, vol.115
, pp. 110-116
-
-
Han, G.1
Wang, R.2
Chen, G.3
Wang, J.4
Xu, R.5
Feng, J.6
Yu, M.7
Wu, X.8
Qian, J.9
Shen, B.10
Li, Y.11
-
87
-
-
33747842285
-
Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: Role of T regulatory cells
-
Soukhareva N, Jiang Y, Scott DW. Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: role of T regulatory cells. Cell Immunol. 2006;240:41-6.
-
(2006)
Cell Immunol
, vol.240
, pp. 41-46
-
-
Soukhareva, N.1
Jiang, Y.2
Scott, D.W.3
-
88
-
-
34248210131
-
The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice
-
Pop SM, Wong CP, He Q, Wang Y, Wallet MA, Goudy KS, Tisch R. The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice. Diabetes. 2007;56:1395-402.
-
(2007)
Diabetes
, vol.56
, pp. 1395-1402
-
-
Pop, S.M.1
Wong, C.P.2
He, Q.3
Wang, Y.4
Wallet, M.A.5
Goudy, K.S.6
Tisch, R.7
-
89
-
-
0037530413
-
More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice
-
Seifarth C, Pop S, Liu B, Wong CP, Tisch R. More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice. J Immunol. 2003;171:469-76.
-
(2003)
J Immunol
, vol.171
, pp. 469-476
-
-
Seifarth, C.1
Pop, S.2
Liu, B.3
Wong, C.P.4
Tisch, R.5
-
90
-
-
0038204841
-
Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase
-
Jaeckel E, Klein L, Martin-Orozco N, von Boehmer H. Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase. J Exp Med. 2003;197:1635-44.
-
(2003)
J Exp Med
, vol.197
, pp. 1635-1644
-
-
Jaeckel, E.1
Klein, L.2
Martin-Orozco, N.3
von Boehmer, H.4
-
91
-
-
26944475538
-
Tolerance induction via a B-cell delivered gene therapy-based protocol: Optimization and role of the Ig scaffold
-
Lei TC, Su Y, Scott DW. Tolerance induction via a B-cell delivered gene therapy-based protocol: optimization and role of the Ig scaffold. Cell Immunol. 2005;235:12-20.
-
(2005)
Cell Immunol
, vol.235
, pp. 12-20
-
-
Lei, T.C.1
Su, Y.2
Scott, D.W.3
-
92
-
-
0031093505
-
Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients
-
Zambidis ET, Barth RK, Scott DW. Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients. J Immunol. 1997;158:2174-82.
-
(1997)
J Immunol
, vol.158
, pp. 2174-2182
-
-
Zambidis, E.T.1
Barth, R.K.2
Scott, D.W.3
-
93
-
-
0034011748
-
B cell tolerance and autoimmunity
-
Tsubata T, Honjo T. B cell tolerance and autoimmunity. Rev Immunogenet. 2000;2:18-25.
-
(2000)
Rev Immunogenet
, vol.2
, pp. 18-25
-
-
Tsubata, T.1
Honjo, T.2
-
94
-
-
0036569428
-
Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases
-
Melo ME, Qian J, El-Amine M, Agarwal RK, Soukhareva N, Kang Y, Scott DW. Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases. J Immunol. 2002;168:4788-95.
-
(2002)
J Immunol
, vol.168
, pp. 4788-4795
-
-
Melo, M.E.1
Qian, J.2
El-Amine, M.3
Agarwal, R.K.4
Soukhareva, N.5
Kang, Y.6
Scott, D.W.7
-
95
-
-
5444221869
-
Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: A role for CD4+ regulatory T cells and TGF-beta?
-
Song L, Wang J, Wang R, Yu M, Sun Y, Han G, Li Y, Qian J, Scott DW, Kang Y, Soukhareva N, Shen B. Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-beta? Gene Ther. 2004;11:1487-96.
-
(2004)
Gene Ther
, vol.11
, pp. 1487-1496
-
-
Song, L.1
Wang, J.2
Wang, R.3
Yu, M.4
Sun, Y.5
Han, G.6
Li, Y.7
Qian, J.8
Scott, D.W.9
Kang, Y.10
Soukhareva, N.11
Shen, B.12
-
96
-
-
0036933006
-
Decreased insulitis and blood glucose levels after injection of GAD-transduced lymphocytes into NOD mice
-
Li F, Filippova M, Fagoaga O, Nehlsen-Cannarella S, Escher A. Decreased insulitis and blood glucose levels after injection of GAD-transduced lymphocytes into NOD mice. Mol Ther. 2002;6:701-9.
-
(2002)
Mol Ther
, vol.6
, pp. 701-709
-
-
Li, F.1
Filippova, M.2
Fagoaga, O.3
Nehlsen-Cannarella, S.4
Escher, A.5
-
97
-
-
33751247344
-
Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice
-
Chan J, Clements W, Field J, Nasa Z, Lock P, Yap F, Toh BH, Alderuccio F. Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice. J Gene Med. 2006;8:1281-90.
-
(2006)
J Gene Med
, vol.8
, pp. 1281-1290
-
-
Chan, J.1
Clements, W.2
Field, J.3
Nasa, Z.4
Lock, P.5
Yap, F.6
Toh, B.H.7
Alderuccio, F.8
-
98
-
-
0038326717
-
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes
-
Steptoe RJ, Ritchie JM, Harrison LC. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J Clin Invest. 2003;111:1357-63.
-
(2003)
J Clin Invest
, vol.111
, pp. 1357-1363
-
-
Steptoe, R.J.1
Ritchie, J.M.2
Harrison, L.C.3
-
99
-
-
0024500755
-
T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
-
Boitard C, Yasunami R, Dardenne M, Bach JF. T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J Exp Med. 1989;169:1669-80.
-
(1989)
J Exp Med
, vol.169
, pp. 1669-1680
-
-
Boitard, C.1
Yasunami, R.2
Dardenne, M.3
Bach, J.F.4
-
100
-
-
16844365788
-
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
-
Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol. 2005;6:345-52.
-
(2005)
Nat Immunol
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
101
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon B, Lenschow DJ, Rhee L, Ashourian N, Singh B, Sharpe A, Bluestone JA. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 2000;12:431-40.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
Ashourian, N.4
Singh, B.5
Sharpe, A.6
Bluestone, J.A.7
-
102
-
-
2942692039
-
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
-
Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med. 2004;199:1467-77.
-
(2004)
J Exp Med
, vol.199
, pp. 1467-1477
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
Toy, P.4
Steinman, R.M.5
-
103
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299:1057-61.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
104
-
-
12744262844
-
Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes
-
Jaeckel E, von Boehmer H, Manns MP. Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes. Diabetes. 2005;54:306-10.
-
(2005)
Diabetes
, vol.54
, pp. 306-310
-
-
Jaeckel, E.1
von Boehmer, H.2
Manns, M.P.3
-
105
-
-
34248593473
-
Converting antigen-specific diabetogenic CD4 and CD8 T cells to TGF-beta producing non-pathogenic regulatory cells following FoxP3 transduction
-
Peng J, Dicker B, Du W, Tang F, Nguyen P, Geiger T, Wong FS, Wen L. Converting antigen-specific diabetogenic CD4 and CD8 T cells to TGF-beta producing non-pathogenic regulatory cells following FoxP3 transduction. J Autoimmun. 2007;28:188-200.
-
(2007)
J Autoimmun
, vol.28
, pp. 188-200
-
-
Peng, J.1
Dicker, B.2
Du, W.3
Tang, F.4
Nguyen, P.5
Geiger, T.6
Wong, F.S.7
Wen, L.8
-
106
-
-
34547103003
-
Foxp3-expressing CD4(+)T cells under the control of INF-gamma promoter prevent diabetes in NOD mice
-
Wang R, Han G, Wang J, Song L, Chen G, Xu R, Yu M, Qian J, Shen B, Li Y. Foxp3-expressing CD4(+)T cells under the control of INF-gamma promoter prevent diabetes in NOD mice. Mol Ther. 2007;15:1551-7.
-
(2007)
Mol Ther
, vol.15
, pp. 1551-1557
-
-
Wang, R.1
Han, G.2
Wang, J.3
Song, L.4
Chen, G.5
Xu, R.6
Yu, M.7
Qian, J.8
Shen, B.9
Li, Y.10
-
107
-
-
34548534750
-
Transplant tolerance: Is it really free of concerns?
-
Zhao Y, Li XC. Transplant tolerance: is it really free of concerns? Trends Immunol. 2007;28:376-7.
-
(2007)
Trends Immunol
, vol.28
, pp. 376-377
-
-
Zhao, Y.1
Li, X.C.2
-
108
-
-
0028922437
-
Genetic control of autoimmune diabetes in the NOD mouse
-
Wicker LS, Todd JA, Peterson LB. Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol. 1995;13:179-200.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 179-200
-
-
Wicker, L.S.1
Todd, J.A.2
Peterson, L.B.3
-
109
-
-
0031847984
-
Molecular basis for HLA-DQ associations with IDDM
-
Nepom GT, Kwok WW. Molecular basis for HLA-DQ associations with IDDM. Diabetes. 1998;47:1177-84.
-
(1998)
Diabetes
, vol.47
, pp. 1177-1184
-
-
Nepom, G.T.1
Kwok, W.W.2
-
110
-
-
0032403094
-
The role of MHC class II molecules in susceptibility and resistance to autoimmunity
-
McDevitt H. The role of MHC class II molecules in susceptibility and resistance to autoimmunity. Curr Opin Immunol. 1998;10:677-81.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 677-681
-
-
McDevitt, H.1
-
111
-
-
0001657878
-
Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: A family study
-
Morel PA, Dorman JS, Todd JA, McDevitt HO, Trucco M. Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci U S A. 1988;85:8111-5.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 8111-8115
-
-
Morel, P.A.1
Dorman, J.S.2
Todd, J.A.3
McDevitt, H.O.4
Trucco, M.5
-
113
-
-
0033756922
-
DR- and DQ-associated protection from type 1A diabetes: Comparison of DRB1*1401 and DQA1*0102-DQB1*0602*
-
Redondo MJ, Kawasaki E, Mulgrew CL, Noble JA, Erlich HA, Freed BM, Lie BA, Thorsby E, Eisenbarth GS, Undlien DE, Ronningen KS. DR- and DQ-associated protection from type 1A diabetes: comparison of DRB1*1401 and DQA1*0102-DQB1*0602*. J Clin Endocrinol Metab. 2000;85:3793-7.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3793-3797
-
-
Redondo, M.J.1
Kawasaki, E.2
Mulgrew, C.L.3
Noble, J.A.4
Erlich, H.A.5
Freed, B.M.6
Lie, B.A.7
Thorsby, E.8
Eisenbarth, G.S.9
Undlien, D.E.10
Ronningen, K.S.11
-
114
-
-
0022646067
-
The NOD mouse: Recessive diabetogenic gene in the major histocompatibility complex
-
Hattori M, Buse JB, Jackson RA, Glimcher L, Dorf ME, Minami M, Makino S, Moriwaki K, Kuzuya H, Imura H, Strauss WM, Seidman JG, Eisenbarth GS. The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex. Science. 1986;231:733-5.
-
(1986)
Science
, vol.231
, pp. 733-735
-
-
Hattori, M.1
Buse, J.B.2
Jackson, R.A.3
Glimcher, L.4
Dorf, M.E.5
Minami, M.6
Makino, S.7
Moriwaki, K.8
Kuzuya, H.9
Imura, H.10
Strauss, W.M.11
Seidman, J.G.12
Eisenbarth, G.S.13
-
115
-
-
0003403213
-
The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique
-
Acha-Orbea H, McDevitt HO. The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique. Proc Natl Acad Sci U S A. 1987;84:2435-9.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 2435-2439
-
-
Acha-Orbea, H.1
McDevitt, H.O.2
-
116
-
-
0034079792
-
Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD65 in transgenic mice
-
Abraham RS, Kudva YC, Wilson SB, Strominger JL, David CS. Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD65 in transgenic mice. Diabetes. 2000;49:548-54.
-
(2000)
Diabetes
, vol.49
, pp. 548-554
-
-
Abraham, R.S.1
Kudva, Y.C.2
Wilson, S.B.3
Strominger, J.L.4
David, C.S.5
-
117
-
-
0034697101
-
A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes
-
Corper AL, Stratmann T, Apostolopoulos V, Scott CA, Garcia KC, Kang AS, Wilson IA, Teyton L. A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes. Science. 2000;288:505-11.
-
(2000)
Science
, vol.288
, pp. 505-511
-
-
Corper, A.L.1
Stratmann, T.2
Apostolopoulos, V.3
Scott, C.A.4
Garcia, K.C.5
Kang, A.S.6
Wilson, I.A.7
Teyton, L.8
-
118
-
-
0032400950
-
Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus
-
Ettinger RA, Liu AW, Nepom GT, Kwok WW. Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus. J Immunol. 1998;161:6439-45.
-
(1998)
J Immunol
, vol.161
, pp. 6439-6445
-
-
Ettinger, R.A.1
Liu, A.W.2
Nepom, G.T.3
Kwok, W.W.4
-
119
-
-
0034664250
-
The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder
-
Stratmann T, Apostolopoulos V, Mallet-Designe V, Corper AL, Scott CA, Wilson IA, Kang AS, Teyton L. The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder. J Immunol. 2000;165:3214-25.
-
(2000)
J Immunol
, vol.165
, pp. 3214-3225
-
-
Stratmann, T.1
Apostolopoulos, V.2
Mallet-Designe, V.3
Corper, A.L.4
Scott, C.A.5
Wilson, I.A.6
Kang, A.S.7
Teyton, L.8
-
120
-
-
2642654250
-
Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities
-
Luhder F, Katz J, Benoist C, Mathis D. Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities. J Exp Med. 1998;187:379-87.
-
(1998)
J Exp Med
, vol.187
, pp. 379-387
-
-
Luhder, F.1
Katz, J.2
Benoist, C.3
Mathis, D.4
-
121
-
-
0027340693
-
An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells
-
Singer SM, Tisch R, Yang X, McDevitt HO. An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells. Proc Natl Acad Sci U S A. 1993;90:9566-70.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9566-9570
-
-
Singer, S.M.1
Tisch, R.2
Yang, X.3
McDevitt, H.O.4
-
122
-
-
0024947844
-
An explanation for the protective effect of the MHC class II I-E molecule in murine diabetes
-
Reich EP, Sherwin RS, Kanagawa O, Janeway CA Jr. An explanation for the protective effect of the MHC class II I-E molecule in murine diabetes. Nature. 1989;341:326-8.
-
(1989)
Nature
, vol.341
, pp. 326-328
-
-
Reich, E.P.1
Sherwin, R.S.2
Kanagawa, O.3
Janeway Jr., C.A.4
-
123
-
-
0024459761
-
Development of autoimmune insulitis is prevented in E alpha d but not in A beta k NOD transgenic mice
-
Uehira M, Uno M, Kurner T, Kikutani H, Mori K, Inomoto T, Uede T, Miyazaki J, Nishimoto H, Kishimoto T, et al. Development of autoimmune insulitis is prevented in E alpha d but not in A beta k NOD transgenic mice. Int Immunol. 1989;1:209-13.
-
(1989)
Int Immunol
, vol.1
, pp. 209-213
-
-
Uehira, M.1
Uno, M.2
Kurner, T.3
Kikutani, H.4
Mori, K.5
Inomoto, T.6
Uede, T.7
Miyazaki, J.8
Nishimoto, H.9
Kishimoto, T.10
-
124
-
-
0025322995
-
Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A beta-chain or normal I-E alpha-chain
-
Lund T, O'Reilly L, Hutchings P, Kanagawa O, Simpson E, Gravely R, Chandler P, Dyson J, Picard JK, Edwards A, Kioussis D, Cooke A. Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A beta-chain or normal I-E alpha-chain. Nature. 1990;345:727-9.
-
(1990)
Nature
, vol.345
, pp. 727-729
-
-
Lund, T.1
O'Reilly, L.2
Hutchings, P.3
Kanagawa, O.4
Simpson, E.5
Gravely, R.6
Chandler, P.7
Dyson, J.8
Picard, J.K.9
Edwards, A.10
Kioussis, D.11
Cooke, A.12
-
125
-
-
0031690196
-
Prevention of diabetes in NOD mice by a mutated I-Ab transgene
-
Singer SM, Tisch R, Yang XD, Sytwu HK, Liblau R, McDevitt HO. Prevention of diabetes in NOD mice by a mutated I-Ab transgene. Diabetes. 1998;47:1570-7.
-
(1998)
Diabetes
, vol.47
, pp. 1570-1577
-
-
Singer, S.M.1
Tisch, R.2
Yang, X.D.3
Sytwu, H.K.4
Liblau, R.5
McDevitt, H.O.6
-
126
-
-
0030779118
-
A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
-
Schmidt D, Verdaguer J, Averill N, Santamaria P. A mechanism for the major histocompatibility complex-linked resistance to autoimmunity. J Exp Med. 1997;186:1059-75.
-
(1997)
J Exp Med
, vol.186
, pp. 1059-1075
-
-
Schmidt, D.1
Verdaguer, J.2
Averill, N.3
Santamaria, P.4
-
127
-
-
0025362072
-
Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice
-
Miyazaki T, Uno M, Uehira M, Kikutani H, Kishimoto T, Kimoto M, Nishimoto H, Miyazaki J, Yamamura K. Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice. Nature. 1990;345:722-4.
-
(1990)
Nature
, vol.345
, pp. 722-724
-
-
Miyazaki, T.1
Uno, M.2
Uehira, M.3
Kikutani, H.4
Kishimoto, T.5
Kimoto, M.6
Nishimoto, H.7
Miyazaki, J.8
Yamamura, K.9
-
128
-
-
0025326947
-
Prevention of diabetes in non-obese diabetic I-Ak transgenic mice
-
Slattery RM, Kjer-Nielsen L, Allison J, Charlton B, Mandel TE, Miller JF. Prevention of diabetes in non-obese diabetic I-Ak transgenic mice. Nature. 1990;345:724-6.
-
(1990)
Nature
, vol.345
, pp. 724-726
-
-
Slattery, R.M.1
Kjer-Nielsen, L.2
Allison, J.3
Charlton, B.4
Mandel, T.E.5
Miller, J.F.6
-
129
-
-
0033561541
-
Autoantigen-independent deletion of diabetogenic CD4+ thymocytes by protective MHC class II molecules
-
Schmidt D, Amrani A, Verdaguer J, Bou S, Santamaria P. Autoantigen-independent deletion of diabetogenic CD4+ thymocytes by protective MHC class II molecules. J Immunol. 1999;162:4627-36.
-
(1999)
J Immunol
, vol.162
, pp. 4627-4636
-
-
Schmidt, D.1
Amrani, A.2
Verdaguer, J.3
Bou, S.4
Santamaria, P.5
-
130
-
-
0029671326
-
Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice
-
Li H, Kaufman CL, Boggs SS, Johnson PC, Patrene KD, Ildstad ST. Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice. J Immunol. 1996;156:380-8.
-
(1996)
J Immunol
, vol.156
, pp. 380-388
-
-
Li, H.1
Kaufman, C.L.2
Boggs, S.S.3
Johnson, P.C.4
Patrene, K.D.5
Ildstad, S.T.6
-
131
-
-
0029092748
-
-
Li H, Colson YL, Ildstad ST. Mixed allogeneic chimerism achieved by lethal and nonlethal conditioning approaches induces donor-specific tolerance to simultaneous islet allografts. Transplantation. 1995;60:523-9.
-
Li H, Colson YL, Ildstad ST. Mixed allogeneic chimerism achieved by lethal and nonlethal conditioning approaches induces donor-specific tolerance to simultaneous islet allografts. Transplantation. 1995;60:523-9.
-
-
-
-
132
-
-
0034998737
-
Impact of bone marrow transplantation on type I diabetes
-
Domenick MA, Ildstad ST. Impact of bone marrow transplantation on type I diabetes. World J Surg. 2001;25:474-80.
-
(2001)
World J Surg
, vol.25
, pp. 474-480
-
-
Domenick, M.A.1
Ildstad, S.T.2
-
133
-
-
0037219227
-
Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice
-
Beilhack GF, Scheffold YC, Weissman IL, Taylor C, Jerabek L, Burge MJ, Masek MA, Shizuru JA. Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice. Diabetes. 2003;52:59-68.
-
(2003)
Diabetes
, vol.52
, pp. 59-68
-
-
Beilhack, G.F.1
Scheffold, Y.C.2
Weissman, I.L.3
Taylor, C.4
Jerabek, L.5
Burge, M.J.6
Masek, M.A.7
Shizuru, J.A.8
-
134
-
-
0037446806
-
A substantial level of donor hematopoietic chimerism is required to protect donorspecific islet grafts in diabetic nod mice
-
Guo Z, Wu T, Sozen H, Pan Y, Heuss N, Kalscheuer H, Sutherland DE, Blazar BR, Hering BJ. A substantial level of donor hematopoietic chimerism is required to protect donorspecific islet grafts in diabetic nod mice. Transplantation. 2003;75:909-15.
-
(2003)
Transplantation
, vol.75
, pp. 909-915
-
-
Guo, Z.1
Wu, T.2
Sozen, H.3
Pan, Y.4
Heuss, N.5
Kalscheuer, H.6
Sutherland, D.E.7
Blazar, B.R.8
Hering, B.J.9
-
135
-
-
0034654374
-
Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: Absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in isletallografted NOD/Lt mice
-
Seung E, Iwakoshi N, Woda BA, Markees TG, Mordes JP, Rossini AA, Greiner DL. Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in isletallografted NOD/Lt mice. Blood. 2000;95:2175-82.
-
(2000)
Blood
, vol.95
, pp. 2175-2182
-
-
Seung, E.1
Iwakoshi, N.2
Woda, B.A.3
Markees, T.G.4
Mordes, J.P.5
Rossini, A.A.6
Greiner, D.L.7
-
136
-
-
0141693112
-
Induction of T cell tolerance to a protein expressed in the cytoplasm through retroviral-mediated gene transfer
-
Tian C, Bagley J, Kaye J, Iacomini J. Induction of T cell tolerance to a protein expressed in the cytoplasm through retroviral-mediated gene transfer. J Gene Med. 2003;5:359-65.
-
(2003)
J Gene Med
, vol.5
, pp. 359-365
-
-
Tian, C.1
Bagley, J.2
Kaye, J.3
Iacomini, J.4
-
137
-
-
0037103238
-
Induction of central deletional T cell tolerance by gene therapy
-
Kang ES, Iacomini J. Induction of central deletional T cell tolerance by gene therapy. J Immunol. 2002;169:1930-5.
-
(2002)
J Immunol
, vol.169
, pp. 1930-1935
-
-
Kang, E.S.1
Iacomini, J.2
-
138
-
-
0012365354
-
Inducing tolerance by molecular chimerism
-
Iacomini J, Bracy JL. Inducing tolerance by molecular chimerism. Graft. 2001;4:102-4.
-
(2001)
Graft
, vol.4
, pp. 102-104
-
-
Iacomini, J.1
Bracy, J.L.2
-
139
-
-
0034330694
-
Induction of B-cell tolerance by retroviral gene therapy
-
Bracy JL, Iacomini J. Induction of B-cell tolerance by retroviral gene therapy. Blood. 2000;96:3008-15.
-
(2000)
Blood
, vol.96
, pp. 3008-3015
-
-
Bracy, J.L.1
Iacomini, J.2
-
140
-
-
0032544673
-
Inhibition of xenoreactive natural antibody production by retroviral gene therapy
-
Bracy JL, Sachs DH, Iacomini J. Inhibition of xenoreactive natural antibody production by retroviral gene therapy. Science. 1998;281:1845-7.
-
(1998)
Science
, vol.281
, pp. 1845-1847
-
-
Bracy, J.L.1
Sachs, D.H.2
Iacomini, J.3
-
141
-
-
0035666554
-
Induction of molecular chimerism by gene therapy prevents antibody-mediated heart transplant rejection
-
Bracy JL, Chase CM, Russell PS, Mauiyyedi S, Colvin RB, Iacomini J. Induction of molecular chimerism by gene therapy prevents antibody-mediated heart transplant rejection. Gene Ther. 2001;8:1738-44.
-
(2001)
Gene Ther
, vol.8
, pp. 1738-1744
-
-
Bracy, J.L.1
Chase, C.M.2
Russell, P.S.3
Mauiyyedi, S.4
Colvin, R.B.5
Iacomini, J.6
-
142
-
-
17544386950
-
Establishing immunological tolerance through the induction of molecular chimerism
-
Bagley J, Bracy JL, Tian C, Kang ES, Iacomini J. Establishing immunological tolerance through the induction of molecular chimerism. Front Biosci. 2002;7:d1331-7.
-
(2002)
Front Biosci
, vol.7
-
-
Bagley, J.1
Bracy, J.L.2
Tian, C.3
Kang, E.S.4
Iacomini, J.5
-
143
-
-
9644252861
-
Prevention of type 1 diabetes by gene therapy
-
Tian C, Bagley J, Cretin N, Seth N, Wucherpfennig KW, Iacomini J. Prevention of type 1 diabetes by gene therapy. J Clin Invest. 2004;114:969-78.
-
(2004)
J Clin Invest
, vol.114
, pp. 969-978
-
-
Tian, C.1
Bagley, J.2
Cretin, N.3
Seth, N.4
Wucherpfennig, K.W.5
Iacomini, J.6
-
144
-
-
0037477605
-
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
-
Ansari MJ, Salama AD, Chitnis T, Smith RN, Yagita H, Akiba H, Yamazaki T, Azuma M, Iwai H, Khoury SJ, Auchincloss H Jr, Sayegh MH. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med. 2003;198:63-9.
-
(2003)
J Exp Med
, vol.198
, pp. 63-69
-
-
Ansari, M.J.1
Salama, A.D.2
Chitnis, T.3
Smith, R.N.4
Yagita, H.5
Akiba, H.6
Yamazaki, T.7
Azuma, M.8
Iwai, H.9
Khoury, S.J.10
Auchincloss Jr, H.11
Sayegh, M.H.12
-
145
-
-
38449092694
-
Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy
-
Tian C, Ansari MJ, Paez-Cortez J, Bagley J, Godwin J, Donnarumma M, Sayegh MH, Iacomini J. Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy. J Immunol. 2007;179:6762-9.
-
(2007)
J Immunol
, vol.179
, pp. 6762-6769
-
-
Tian, C.1
Ansari, M.J.2
Paez-Cortez, J.3
Bagley, J.4
Godwin, J.5
Donnarumma, M.6
Sayegh, M.H.7
Iacomini, J.8
-
146
-
-
0032146564
-
IL-1 produced and released endogenously within human islets inhibits beta cell function
-
Arnush M, Heitmeier MR, Scarim AL, Marino MH, Manning PT, Corbett JA. IL-1 produced and released endogenously within human islets inhibits beta cell function. J Clin Invest. 1998;102:516-26.
-
(1998)
J Clin Invest
, vol.102
, pp. 516-526
-
-
Arnush, M.1
Heitmeier, M.R.2
Scarim, A.L.3
Marino, M.H.4
Manning, P.T.5
Corbett, J.A.6
-
147
-
-
33846219561
-
-
Borjesson A, Andersson AK, Sandler S. Survival of an islet allograft deficient in iNOS after implantation into diabetic NOD mice. Cell Transplant. 2006;15:769-75.
-
Borjesson A, Andersson AK, Sandler S. Survival of an islet allograft deficient in iNOS after implantation into diabetic NOD mice. Cell Transplant. 2006;15:769-75.
-
-
-
-
148
-
-
0027054055
-
Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide
-
Corbett JA, Wang JL, Sweetland MA, Lancaster JR Jr, McDaniel ML. Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide. J Clin Invest. 1992;90:2384-91.
-
(1992)
J Clin Invest
, vol.90
, pp. 2384-2391
-
-
Corbett, J.A.1
Wang, J.L.2
Sweetland, M.A.3
Lancaster Jr, J.R.4
McDaniel, M.L.5
-
149
-
-
0032830997
-
Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro
-
Giannoukakis N, Rudert WA, Ghivizzani SC, Gambotto A, Ricordi C, Trucco M, Robbins PD. Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro. Diabetes. 1999;48:1730-6.
-
(1999)
Diabetes
, vol.48
, pp. 1730-1736
-
-
Giannoukakis, N.1
Rudert, W.A.2
Ghivizzani, S.C.3
Gambotto, A.4
Ricordi, C.5
Trucco, M.6
Robbins, P.D.7
-
150
-
-
21344471092
-
Immune cell infiltration, cytokine expression, and beta-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW.1AR1/Ztm-iddm rat
-
Jorns A, Gunther A, Hedrich HJ, Wedekind D, Tiedge M, Lenzen S. Immune cell infiltration, cytokine expression, and beta-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW.1AR1/Ztm-iddm rat. Diabetes. 2005;54:2041-52.
-
(2005)
Diabetes
, vol.54
, pp. 2041-2052
-
-
Jorns, A.1
Gunther, A.2
Hedrich, H.J.3
Wedekind, D.4
Tiedge, M.5
Lenzen, S.6
-
151
-
-
3142659582
-
Immunoregulatory role of nitric oxide in Kilham rat virus-induced autoimmune diabetes in DRBB rats
-
Mendez, II, Chung YH, Jun HS, Yoon JW. Immunoregulatory role of nitric oxide in Kilham rat virus-induced autoimmune diabetes in DRBB rats. J Immunol. 2004;173:1327-35.
-
(2004)
J Immunol
, vol.173
, pp. 1327-1335
-
-
Mendez, I.1
Chung, Y.H.2
Jun, H.S.3
Yoon, J.W.4
-
152
-
-
0032855209
-
Infection of intact human islets by a lentiviral vector
-
Giannoukakis N, Mi Z, Gambotto A, Eramo A, Ricordi C, Trucco M, Robbins P. Infection of intact human islets by a lentiviral vector. Gene Ther. 1999;6:1545-51.
-
(1999)
Gene Ther
, vol.6
, pp. 1545-1551
-
-
Giannoukakis, N.1
Mi, Z.2
Gambotto, A.3
Eramo, A.4
Ricordi, C.5
Trucco, M.6
Robbins, P.7
-
153
-
-
13244278034
-
Adenoviral overexpression of interleukin-1 receptor antagonist protein increases beta-cell replication in rat pancreatic islets
-
Tellez N, Montolio M, Biarnes M, Castano E, Soler J, Montanya E. Adenoviral overexpression of interleukin-1 receptor antagonist protein increases beta-cell replication in rat pancreatic islets. Gene Ther. 2005;12:120-8.
-
(2005)
Gene Ther
, vol.12
, pp. 120-128
-
-
Tellez, N.1
Montolio, M.2
Biarnes, M.3
Castano, E.4
Soler, J.5
Montanya, E.6
-
154
-
-
33846826610
-
Adenoviral overproduction of interleukin-1 receptor antagonist increases beta cell replication and mass in syngeneically transplanted islets, and improves metabolic outcome
-
Tellez N, Montolio M, Estil-les E, Escoriza J, Soler J, Montanya E. Adenoviral overproduction of interleukin-1 receptor antagonist increases beta cell replication and mass in syngeneically transplanted islets, and improves metabolic outcome. Diabetologia. 2007;50:602-11.
-
(2007)
Diabetologia
, vol.50
, pp. 602-611
-
-
Tellez, N.1
Montolio, M.2
Estil-les, E.3
Escoriza, J.4
Soler, J.5
Montanya, E.6
-
155
-
-
6344223648
-
Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans
-
Bertera S, Alexander AM, Crawford ML, Papworth G, Watkins SC, Robbins PD, Trucco M. Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans. Exp Diabesity Res. 2004;5:201-10.
-
(2004)
Exp Diabesity Res
, vol.5
, pp. 201-210
-
-
Bertera, S.1
Alexander, A.M.2
Crawford, M.L.3
Papworth, G.4
Watkins, S.C.5
Robbins, P.D.6
Trucco, M.7
-
156
-
-
5444226677
-
-
Machen J, Bertera S, Chang Y, Bottino R, Balamurugan AN, Robbins PD, Trucco M, Giannoukakis N. Prolongation of islet allograft survival following ex vivo transduction with adenovirus encoding a soluble type 1 TNF receptor-Ig fusion decoy. Gene Ther. 2004;11:1506-14.
-
Machen J, Bertera S, Chang Y, Bottino R, Balamurugan AN, Robbins PD, Trucco M, Giannoukakis N. Prolongation of islet allograft survival following ex vivo transduction with adenovirus encoding a soluble type 1 TNF receptor-Ig fusion decoy. Gene Ther. 2004;11:1506-14.
-
-
-
-
157
-
-
0035039750
-
Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene
-
Contreras JL, Bilbao G, Smyth CA, Jiang XL, Eckhoff DE, Jenkins SM, Thomas FT, Curiel DT, Thomas JM. Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene. Transplantation. 2001;71:1015-23.
-
(2001)
Transplantation
, vol.71
, pp. 1015-1023
-
-
Contreras, J.L.1
Bilbao, G.2
Smyth, C.A.3
Jiang, X.L.4
Eckhoff, D.E.5
Jenkins, S.M.6
Thomas, F.T.7
Curiel, D.T.8
Thomas, J.M.9
-
158
-
-
0034902165
-
Gene transfer of the Bcl-2 gene confers cytoprotection to isolated adult porcine pancreatic islets exposed to xenoreactive antibodies and complement
-
Contreras JL, Bilbao G, Smyth C, Eckhoff DE, Xiang XL, Jenkins S, Cartner S, Curiel DT, Thomas FT, Thomas JM. Gene transfer of the Bcl-2 gene confers cytoprotection to isolated adult porcine pancreatic islets exposed to xenoreactive antibodies and complement. Surgery. 2001;130:166-74.
-
(2001)
Surgery
, vol.130
, pp. 166-174
-
-
Contreras, J.L.1
Bilbao, G.2
Smyth, C.3
Eckhoff, D.E.4
Xiang, X.L.5
Jenkins, S.6
Cartner, S.7
Curiel, D.T.8
Thomas, F.T.9
Thomas, J.M.10
-
159
-
-
1842584372
-
Codelivery of pro-apoptotic BAX with a DNA vaccine recruits dendritic cells and promotes efficacy of autoimmune diabetes prevention in mice
-
Li AF, Hough J, Henderson D, Escher A. Codelivery of pro-apoptotic BAX with a DNA vaccine recruits dendritic cells and promotes efficacy of autoimmune diabetes prevention in mice. Vaccine. 2004;22:1751-63.
-
(2004)
Vaccine
, vol.22
, pp. 1751-1763
-
-
Li, A.F.1
Hough, J.2
Henderson, D.3
Escher, A.4
-
160
-
-
34548438601
-
Angiopoietin-1 production in islets improves islet engraftment and protects islets from cytokine-induced apoptosis
-
Su D, Zhang N, He J, Qu S, Slusher S, Bottino R, Bertera S, Bromberg J, Dong HH. Angiopoietin-1 production in islets improves islet engraftment and protects islets from cytokine-induced apoptosis. Diabetes. 2007;56:2274-83.
-
(2007)
Diabetes
, vol.56
, pp. 2274-2283
-
-
Su, D.1
Zhang, N.2
He, J.3
Qu, S.4
Slusher, S.5
Bottino, R.6
Bertera, S.7
Bromberg, J.8
Dong, H.H.9
-
161
-
-
34249941467
-
Vascular endothelial growth factor as a survival factor for human islets: Effect of immunosuppressive drugs
-
Cross SE, Richards SK, Clark A, Benest AV, Bates DO, Mathieson PW, Johnson PR, Harper SJ, Smith RM. Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs. Diabetologia. 2007;50:1423-32.
-
(2007)
Diabetologia
, vol.50
, pp. 1423-1432
-
-
Cross, S.E.1
Richards, S.K.2
Clark, A.3
Benest, A.V.4
Bates, D.O.5
Mathieson, P.W.6
Johnson, P.R.7
Harper, S.J.8
Smith, R.M.9
-
162
-
-
4243066440
-
Adenovirus-based vascular endothelial growth factor gene delivery to human pancreatic islets
-
Cheng K, Fraga D, Zhang C, Kotb M, Gaber AO, Guntaka RV, Mahato RI. Adenovirus-based vascular endothelial growth factor gene delivery to human pancreatic islets. Gene Ther. 2004;11:1105-16.
-
(2004)
Gene Ther
, vol.11
, pp. 1105-1116
-
-
Cheng, K.1
Fraga, D.2
Zhang, C.3
Kotb, M.4
Gaber, A.O.5
Guntaka, R.V.6
Mahato, R.I.7
-
163
-
-
34247354627
-
Coexpression of vascular endothelial growth factor and interleukin-1 receptor antagonist for improved human islet survival and function
-
Jia X, Cheng K, Mahato RI. Coexpression of vascular endothelial growth factor and interleukin-1 receptor antagonist for improved human islet survival and function. Mol Pharm. 2007;4:199-207.
-
(2007)
Mol Pharm
, vol.4
, pp. 199-207
-
-
Jia, X.1
Cheng, K.2
Mahato, R.I.3
-
164
-
-
12144290322
-
Elevated vascular endothelial growth factor production in islets improves islet graft vascularization
-
Zhang N, Richter A, Suriawinata J, Harbaran S, Altomonte J, Cong L, Zhang H, Song K, Meseck M, Bromberg J, Dong H. Elevated vascular endothelial growth factor production in islets improves islet graft vascularization. Diabetes. 2004;53:963-70.
-
(2004)
Diabetes
, vol.53
, pp. 963-970
-
-
Zhang, N.1
Richter, A.2
Suriawinata, J.3
Harbaran, S.4
Altomonte, J.5
Cong, L.6
Zhang, H.7
Song, K.8
Meseck, M.9
Bromberg, J.10
Dong, H.11
-
165
-
-
1642498307
-
Vascular endothelial growth factor gene delivery for revascularization in transplanted human islets
-
Narang AS, Cheng K, Henry J, Zhang C, Sabek O, Fraga D, Kotb M, Gaber AO, Mahato RI. Vascular endothelial growth factor gene delivery for revascularization in transplanted human islets. Pharm Res. 2004;21:15-25.
-
(2004)
Pharm Res
, vol.21
, pp. 15-25
-
-
Narang, A.S.1
Cheng, K.2
Henry, J.3
Zhang, C.4
Sabek, O.5
Fraga, D.6
Kotb, M.7
Gaber, A.O.8
Mahato, R.I.9
-
166
-
-
33750591089
-
Co-expression of vascular endothelial growth factor and interleukin-1 receptor antagonist improves human islet survival and function
-
Narang AS, Sabek O, Gaber AO, Mahato RI. Co-expression of vascular endothelial growth factor and interleukin-1 receptor antagonist improves human islet survival and function. Pharm Res. 2006;23:1970-82.
-
(2006)
Pharm Res
, vol.23
, pp. 1970-1982
-
-
Narang, A.S.1
Sabek, O.2
Gaber, A.O.3
Mahato, R.I.4
-
167
-
-
0036246629
-
Beta cell expression of IGF-I leads to recovery from type 1 diabetes
-
George M, Ayuso E, Casellas A, Costa C, Devedjian JC, Bosch F. Beta cell expression of IGF-I leads to recovery from type 1 diabetes. J Clin Invest. 2002;109:1153-63.
-
(2002)
J Clin Invest
, vol.109
, pp. 1153-1163
-
-
George, M.1
Ayuso, E.2
Casellas, A.3
Costa, C.4
Devedjian, J.C.5
Bosch, F.6
-
168
-
-
0034509569
-
Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I
-
Giannoukakis N, Mi Z, Rudert WA, Gambotto A, Trucco M, Robbins P. Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I. Gene Ther. 2000;7:2015-22.
-
(2000)
Gene Ther
, vol.7
, pp. 2015-2022
-
-
Giannoukakis, N.1
Mi, Z.2
Rudert, W.A.3
Gambotto, A.4
Trucco, M.5
Robbins, P.6
-
169
-
-
33846239410
-
Adenovirus-mediated expression of the anticoagulant hirudin in human islets: A tool to make the islets biocompatible to blood
-
Cabric S, Elgue G, Nilsson B, Korsgren O, Schmidt P. Adenovirus-mediated expression of the anticoagulant hirudin in human islets: a tool to make the islets biocompatible to blood. Cell Transplant. 2006;15:759-67.
-
(2006)
Cell Transplant
, vol.15
, pp. 759-767
-
-
Cabric, S.1
Elgue, G.2
Nilsson, B.3
Korsgren, O.4
Schmidt, P.5
-
170
-
-
31444455001
-
Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: Reduced insulin antibody titres and preserved beta cell function
-
Nielsen LB, Mortensen HB, Chiarelli F, Holl R, Swift P, de Beaufort C, Pociot F, Hougaard P, Gammeltoft S, Knip M, Hansen L. Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: reduced insulin antibody titres and preserved beta cell function. Diabetologia. 2006;49:71-4.
-
(2006)
Diabetologia
, vol.49
, pp. 71-74
-
-
Nielsen, L.B.1
Mortensen, H.B.2
Chiarelli, F.3
Holl, R.4
Swift, P.5
de Beaufort, C.6
Pociot, F.7
Hougaard, P.8
Gammeltoft, S.9
Knip, M.10
Hansen, L.11
-
171
-
-
12844263380
-
Residual beta-cell function and male/female ratio are higher in incident young adults than in children: The registry of type 1 diabetes of the province of Turin, Italy, 1984-2000
-
Bruno G, Cerutti F, Merletti F, Cavallo-Perin P, Gandolfo E, Rivetti M, Runzo C, Pinach S, Pagano G. Residual beta-cell function and male/female ratio are higher in incident young adults than in children: the registry of type 1 diabetes of the province of Turin, Italy, 1984-2000. Diabetes Care. 2005;28:312-7.
-
(2005)
Diabetes Care
, vol.28
, pp. 312-317
-
-
Bruno, G.1
Cerutti, F.2
Merletti, F.3
Cavallo-Perin, P.4
Gandolfo, E.5
Rivetti, M.6
Runzo, C.7
Pinach, S.8
Pagano, G.9
-
172
-
-
0038027366
-
GLP-1 gene delivery for the treatment of type 2 diabetes
-
Oh S, Lee M, Ko KS, Choi S, Kim SW. GLP-1 gene delivery for the treatment of type 2 diabetes. Mol Ther. 2003;7:478-83.
-
(2003)
Mol Ther
, vol.7
, pp. 478-483
-
-
Oh, S.1
Lee, M.2
Ko, K.S.3
Choi, S.4
Kim, S.W.5
-
173
-
-
40549086289
-
Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats
-
Lee Y, Kwon MK, Kang ES, Park YM, Choi SH, Ahn CW, Kim KS, Park CW, Cha BS, Kim SW, Sung JK, Lee EJ, Lee HC. Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats. J Gene Med. 2008;10:260-8.
-
(2008)
J Gene Med
, vol.10
, pp. 260-268
-
-
Lee, Y.1
Kwon, M.K.2
Kang, E.S.3
Park, Y.M.4
Choi, S.H.5
Ahn, C.W.6
Kim, K.S.7
Park, C.W.8
Cha, B.S.9
Kim, S.W.10
Sung, J.K.11
Lee, E.J.12
Lee, H.C.13
-
174
-
-
33846010782
-
Prolonged remission of diabetes by regeneration of beta cells in diabetic mice treated with recombinant adenoviral vector expressing glucagon-like peptide-1
-
Liu MJ, Shin S, Li N, Shigihara T, Lee YS, Yoon JW, Jun HS. Prolonged remission of diabetes by regeneration of beta cells in diabetic mice treated with recombinant adenoviral vector expressing glucagon-like peptide-1. Mol Ther. 2007;15:86-93.
-
(2007)
Mol Ther
, vol.15
, pp. 86-93
-
-
Liu, M.J.1
Shin, S.2
Li, N.3
Shigihara, T.4
Lee, Y.S.5
Yoon, J.W.6
Jun, H.S.7
-
175
-
-
34249884271
-
In vivo expression of GLP-1/IgG-Fc fusion protein enhances beta-cell mass and protects against streptozotocin-induced diabetes
-
Soltani N, Kumar M, Glinka Y, Prud'homme GJ, Wang Q. In vivo expression of GLP-1/IgG-Fc fusion protein enhances beta-cell mass and protects against streptozotocin-induced diabetes. Gene Ther. 2007;14:981-8.
-
(2007)
Gene Ther
, vol.14
, pp. 981-988
-
-
Soltani, N.1
Kumar, M.2
Glinka, Y.3
Prud'homme, G.J.4
Wang, Q.5
-
176
-
-
0034707028
-
Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue
-
Lee HC, Kim SJ, Kim KS, Shin HC, Yoon JW. Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue. Nature. 2000;408:483-8.
-
(2000)
Nature
, vol.408
, pp. 483-488
-
-
Lee, H.C.1
Kim, S.J.2
Kim, K.S.3
Shin, H.C.4
Yoon, J.W.5
-
177
-
-
0031730473
-
Adenovirus-mediated transfer of a modified human proinsulin gene reverses hyperglycemia in diabetic mice
-
Short DK, Okada S, Yamauchi K, Pessin JE. Adenovirus-mediated transfer of a modified human proinsulin gene reverses hyperglycemia in diabetic mice. Am J Physiol. 1998;275:E748-56.
-
(1998)
Am J Physiol
, vol.275
-
-
Short, D.K.1
Okada, S.2
Yamauchi, K.3
Pessin, J.E.4
-
178
-
-
0030946203
-
Hepatic insulin gene expression as treatment for type 1 diabetes mellitus in rats
-
Muzzin P, Eisensmith RC, Copeland KC, Woo SL. Hepatic insulin gene expression as treatment for type 1 diabetes mellitus in rats. Mol Endocrinol. 1997;11:833-7.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 833-837
-
-
Muzzin, P.1
Eisensmith, R.C.2
Copeland, K.C.3
Woo, S.L.4
-
179
-
-
34547701718
-
Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy
-
Ren B, O'Brien BA, Swan MA, Koina ME, Nassif N, Wei MQ, Simpson AM. Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy. Diabetologia. 2007;50:1910-20.
-
(2007)
Diabetologia
, vol.50
, pp. 1910-1920
-
-
Ren, B.1
O'Brien, B.A.2
Swan, M.A.3
Koina, M.E.4
Nassif, N.5
Wei, M.Q.6
Simpson, A.M.7
-
180
-
-
0035915762
-
Glucose-regulated insulin expression in diabetic rats
-
Barry SC, Ramesh N, Lejnieks D, Simonson WT, Kemper L, Lernmark A, Osborne WR. Glucose-regulated insulin expression in diabetic rats. Hum Gene Ther. 2001;12:131-9.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 131-139
-
-
Barry, S.C.1
Ramesh, N.2
Lejnieks, D.3
Simonson, W.T.4
Kemper, L.5
Lernmark, A.6
Osborne, W.R.7
-
181
-
-
17644425265
-
Plasmid-electroporated primary hepatocytes acquire quasi-physiological secretion of human insulin and restore euglycemia in diabetic mice
-
Chen NK, Sivalingam J, Tan SY, Kon OL. Plasmid-electroporated primary hepatocytes acquire quasi-physiological secretion of human insulin and restore euglycemia in diabetic mice. Gene Ther. 2005;12:655-67.
-
(2005)
Gene Ther
, vol.12
, pp. 655-667
-
-
Chen, N.K.1
Sivalingam, J.2
Tan, S.Y.3
Kon, O.L.4
-
182
-
-
0037184731
-
Glucose-regulated insulin production in hepatocytes
-
Alam T, Sollinger HW. Glucose-regulated insulin production in hepatocytes. Transplantation. 2002;74:1781-7.
-
(2002)
Transplantation
, vol.74
, pp. 1781-1787
-
-
Alam, T.1
Sollinger, H.W.2
-
183
-
-
0033122314
-
Naked plasmid-mediated gene transfer to skeletal muscle ameliorates diabetes mellitus
-
Kon OL, Sivakumar S, Teoh KL, Lok SH, Long YC. Naked plasmid-mediated gene transfer to skeletal muscle ameliorates diabetes mellitus. J Gene Med. 1999;1:186-94.
-
(1999)
J Gene Med
, vol.1
, pp. 186-194
-
-
Kon, O.L.1
Sivakumar, S.2
Teoh, K.L.3
Lok, S.H.4
Long, Y.C.5
-
184
-
-
0034778099
-
Adenoviral vector-mediated insulin gene transfer in the mouse pancreas corrects streptozotocin-induced hyperglycemia
-
Shifrin AL, Auricchio A, Yu QC, Wilson J, Raper SE. Adenoviral vector-mediated insulin gene transfer in the mouse pancreas corrects streptozotocin-induced hyperglycemia. Gene Ther. 2001;8:1480-9.
-
(2001)
Gene Ther
, vol.8
, pp. 1480-1489
-
-
Shifrin, A.L.1
Auricchio, A.2
Yu, Q.C.3
Wilson, J.4
Raper, S.E.5
-
185
-
-
0038472015
-
Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells
-
Zalzman M, Gupta S, Giri RK, Berkovich I, Sappal BS, Karnieli O, Zern MA, Fleischer N, Efrat S. Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells. Proc Natl Acad Sci U S A. 2003;100:7253-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 7253-7258
-
-
Zalzman, M.1
Gupta, S.2
Giri, R.K.3
Berkovich, I.4
Sappal, B.S.5
Karnieli, O.6
Zern, M.A.7
Fleischer, N.8
Efrat, S.9
-
186
-
-
0034068602
-
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
-
Ferber S, Halkin A, Cohen H, Ber I, Einav Y, Goldberg I, Barshack I, Seijffers R, Kopolovic J, Kaiser N, Karasik A. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat Med. 2000;6:568-72.
-
(2000)
Nat Med
, vol.6
, pp. 568-572
-
-
Ferber, S.1
Halkin, A.2
Cohen, H.3
Ber, I.4
Einav, Y.5
Goldberg, I.6
Barshack, I.7
Seijffers, R.8
Kopolovic, J.9
Kaiser, N.10
Karasik, A.11
-
187
-
-
33845957180
-
Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: An ex vivo gene therapy approach
-
Fodor A, Harel C, Fodor L, Armoni M, Salmon P, Trono D, Karnieli E. Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: an ex vivo gene therapy approach. Diabetologia. 2007;50:121-30.
-
(2007)
Diabetologia
, vol.50
, pp. 121-130
-
-
Fodor, A.1
Harel, C.2
Fodor, L.3
Armoni, M.4
Salmon, P.5
Trono, D.6
Karnieli, E.7
-
188
-
-
0041856137
-
Functional, persistent, and extended liver to pancreas transdifferentiation
-
Ber I, Shternhall K, Perl S, Ohanuna Z, Goldberg I, Barshack I, Benvenisti-Zarum L, Meivar-Levy I, Ferber S. Functional, persistent, and extended liver to pancreas transdifferentiation. J Biol Chem. 2003;278:31950-7.
-
(2003)
J Biol Chem
, vol.278
, pp. 31950-31957
-
-
Ber, I.1
Shternhall, K.2
Perl, S.3
Ohanuna, Z.4
Goldberg, I.5
Barshack, I.6
Benvenisti-Zarum, L.7
Meivar-Levy, I.8
Ferber, S.9
-
189
-
-
34247597744
-
Ectopic PDX-1 expression in liver ameliorates type 1 diabetes
-
Shternhall-Ron K, Quintana FJ, Perl S, Meivar-Levy I, Barshack I, Cohen IR, Ferber S. Ectopic PDX-1 expression in liver ameliorates type 1 diabetes. J Autoimmun. 2007;28:134-42.
-
(2007)
J Autoimmun
, vol.28
, pp. 134-142
-
-
Shternhall-Ron, K.1
Quintana, F.J.2
Perl, S.3
Meivar-Levy, I.4
Barshack, I.5
Cohen, I.R.6
Ferber, S.7
-
190
-
-
44949159838
-
Adeno-associated virus-mediated pancreatic and duodenal homeobox gene-1 expression enhanced differentiation of hepatic oval stem cells to insulin-producing cells in diabetic rats
-
Li H, Li X, Lam KS, Tam S, Xiao W, Xu R. Adeno-associated virus-mediated pancreatic and duodenal homeobox gene-1 expression enhanced differentiation of hepatic oval stem cells to insulin-producing cells in diabetic rats. J Biomed Sci. 2008;15:487-97.
-
(2008)
J Biomed Sci
, vol.15
, pp. 487-497
-
-
Li, H.1
Li, X.2
Lam, K.S.3
Tam, S.4
Xiao, W.5
Xu, R.6
-
191
-
-
15944417831
-
PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
-
Kaneto H, Nakatani Y, Miyatsuka T, Matsuoka TA, Matsuhisa M, Hori M, Yamasaki Y. PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes. 2005;54:1009-22.
-
(2005)
Diabetes
, vol.54
, pp. 1009-1022
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
Matsuoka, T.A.4
Matsuhisa, M.5
Hori, M.6
Yamasaki, Y.7
-
192
-
-
9944235761
-
Constitutively active PDX1 induced efficient insulin production in adult murine liver
-
Imai J, Katagiri H, Yamada T, Ishigaki Y, Ogihara T, Uno K, Hasegawa Y, Gao J, Ishihara H, Sasano H, Mizuguchi H, Asano T, Oka Y. Constitutively active PDX1 induced efficient insulin production in adult murine liver. Biochem Biophys Res Commun. 2005;326:402-9.
-
(2005)
Biochem Biophys Res Commun
, vol.326
, pp. 402-409
-
-
Imai, J.1
Katagiri, H.2
Yamada, T.3
Ishigaki, Y.4
Ogihara, T.5
Uno, K.6
Hasegawa, Y.7
Gao, J.8
Ishihara, H.9
Sasano, H.10
Mizuguchi, H.11
Asano, T.12
Oka, Y.13
-
193
-
-
0038413922
-
NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice
-
Kojima H, Fujimiya M, Matsumura K, Younan P, Imaeda H, Maeda M, Chan L. NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Nat Med. 2003;9:596-603.
-
(2003)
Nat Med
, vol.9
, pp. 596-603
-
-
Kojima, H.1
Fujimiya, M.2
Matsumura, K.3
Younan, P.4
Imaeda, H.5
Maeda, M.6
Chan, L.7
-
194
-
-
34447100368
-
Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1
-
Chen S, Ding J, Yu C, Yang B, Wood DR, Grayburn PA. Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1. Gene Ther. 2007;14:1102-10.
-
(2007)
Gene Ther
, vol.14
, pp. 1102-1110
-
-
Chen, S.1
Ding, J.2
Yu, C.3
Yang, B.4
Wood, D.R.5
Grayburn, P.A.6
-
195
-
-
36248934727
-
Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation
-
Karnieli O, Izhar-Prato Y, Bulvik S, Efrat S. Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation. Stem Cells. 2007;25:2837-44.
-
(2007)
Stem Cells
, vol.25
, pp. 2837-2844
-
-
Karnieli, O.1
Izhar-Prato, Y.2
Bulvik, S.3
Efrat, S.4
-
196
-
-
0031793875
-
The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVII. The 14-year incidence and progression of diabetic retinopathy and associated risk factors in type 1 diabetes
-
Klein R, Klein BE, Moss SE, Cruickshanks KJ. The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVII. The 14-year incidence and progression of diabetic retinopathy and associated risk factors in type 1 diabetes. Ophthalmology. 1998;105:1801-15.
-
(1998)
Ophthalmology
, vol.105
, pp. 1801-1815
-
-
Klein, R.1
Klein, B.E.2
Moss, S.E.3
Cruickshanks, K.J.4
-
197
-
-
34548087845
-
Management of diabetic retinopathy: A systematic review
-
Mohamed Q, Gillies MC, Wong TY. Management of diabetic retinopathy: a systematic review. JAMA. 2007;298:902-16.
-
(2007)
JAMA
, vol.298
, pp. 902-916
-
-
Mohamed, Q.1
Gillies, M.C.2
Wong, T.Y.3
-
198
-
-
33646246183
-
Basic and clinical aspects of gene therapy for retinopathy induced by diabetes
-
Ting JH, Martin DK. Basic and clinical aspects of gene therapy for retinopathy induced by diabetes. Curr Gene Ther. 2006;6:193-214.
-
(2006)
Curr Gene Ther
, vol.6
, pp. 193-214
-
-
Ting, J.H.1
Martin, D.K.2
-
199
-
-
33847305368
-
Gene therapy for ocular neovascularization
-
Campochiaro PA. Gene therapy for ocular neovascularization. Curr Gene Ther. 2007;7:25-33.
-
(2007)
Curr Gene Ther
, vol.7
, pp. 25-33
-
-
Campochiaro, P.A.1
-
200
-
-
20844432009
-
Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer
-
Rota R, Riccioni T, Zaccarini M, Lamartina S, Gallo AD, Fusco A, Kovesdi I, Balestrazzi E, Abeni DC, Ali RR, Capogrossi MC. Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer. J Gene Med. 2004;6:992-1002.
-
(2004)
J Gene Med
, vol.6
, pp. 992-1002
-
-
Rota, R.1
Riccioni, T.2
Zaccarini, M.3
Lamartina, S.4
Gallo, A.D.5
Fusco, A.6
Kovesdi, I.7
Balestrazzi, E.8
Abeni, D.C.9
Ali, R.R.10
Capogrossi, M.C.11
-
201
-
-
0034945843
-
Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization
-
Mori K, Duh E, Gehlbach P, Ando A, Takahashi K, Pearlman J, Mori K, Yang HS, Zack DJ, Ettyreddy D, Brough DE, Wei LL, Campochiaro PA. Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization. J Cell Physiol. 2001;188:253-63.
-
(2001)
J Cell Physiol
, vol.188
, pp. 253-263
-
-
Mori, K.1
Duh, E.2
Gehlbach, P.3
Ando, A.4
Takahashi, K.5
Pearlman, J.6
Mori, K.7
Yang, H.S.8
Zack, D.J.9
Ettyreddy, D.10
Brough, D.E.11
Wei, L.L.12
Campochiaro, P.A.13
-
202
-
-
0036798747
-
Inhibition of retinal neovascularization by intraocular viral-mediated delivery of antiangiogenic agents
-
Auricchio A, Behling KC, Maguire AM, O'Connor EM, Bennett J, Wilson JM, Tolentino MJ. Inhibition of retinal neovascularization by intraocular viral-mediated delivery of antiangiogenic agents. Mol Ther. 2002;6:490-4.
-
(2002)
Mol Ther
, vol.6
, pp. 490-494
-
-
Auricchio, A.1
Behling, K.C.2
Maguire, A.M.3
O'Connor, E.M.4
Bennett, J.5
Wilson, J.M.6
Tolentino, M.J.7
-
203
-
-
0037173042
-
Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization
-
Raisler BJ, Berns KI, Grant MB, Beliaev D, Hauswirth WW. Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization. Proc Natl Acad Sci U S A. 2002;99:8909-14.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8909-8914
-
-
Raisler, B.J.1
Berns, K.I.2
Grant, M.B.3
Beliaev, D.4
Hauswirth, W.W.5
-
204
-
-
0034913943
-
Systemically expressed soluble Tie2 inhibits intraocular neovascularization
-
Hangai M, Moon YS, Kitaya N, Chan CK, Wu DY, Peters KG, Ryan SJ, Hinton DR. Systemically expressed soluble Tie2 inhibits intraocular neovascularization. Hum Gene Ther. 2001;12:1311-21.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1311-1321
-
-
Hangai, M.1
Moon, Y.S.2
Kitaya, N.3
Chan, C.K.4
Wu, D.Y.5
Peters, K.G.6
Ryan, S.J.7
Hinton, D.R.8
-
205
-
-
35148861116
-
Helper-dependent adenovirus for the gene therapy of proliferative retinopathies: Stable gene transfer, regulated gene expression and therapeutic efficacy
-
Lamartina S, Cimino M, Roscilli G, Dammassa E, Lazzaro D, Rota R, Ciliberto G, Toniatti C. Helper-dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy. J Gene Med. 2007;9:862-74.
-
(2007)
J Gene Med
, vol.9
, pp. 862-874
-
-
Lamartina, S.1
Cimino, M.2
Roscilli, G.3
Dammassa, E.4
Lazzaro, D.5
Rota, R.6
Ciliberto, G.7
Toniatti, C.8
-
206
-
-
0037301576
-
Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates
-
Lamartina S, Silvi L, Roscilli G, Casimiro D, Simon AJ, Davies ME, Shiver JW, Rinaudo CD, Zampaglione I, Fattori E, Colloca S, Gonzalez Paz O, Laufer R, Bujard H, Cortese R, Ciliberto G, Toniatti C. Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates. Mol Ther. 2003;7:271-80.
-
(2003)
Mol Ther
, vol.7
, pp. 271-280
-
-
Lamartina, S.1
Silvi, L.2
Roscilli, G.3
Casimiro, D.4
Simon, A.J.5
Davies, M.E.6
Shiver, J.W.7
Rinaudo, C.D.8
Zampaglione, I.9
Fattori, E.10
Colloca, S.11
Gonzalez Paz, O.12
Laufer, R.13
Bujard, H.14
Cortese, R.15
Ciliberto, G.16
Toniatti, C.17
-
207
-
-
0038748037
-
Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
-
Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis. 2003;9:210-6.
-
(2003)
Mol Vis
, vol.9
, pp. 210-216
-
-
Reich, S.J.1
Fosnot, J.2
Kuroki, A.3
Tang, W.4
Yang, X.5
Maguire, A.M.6
Bennett, J.7
Tolentino, M.J.8
-
208
-
-
33645139836
-
Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disorders
-
Campochiaro PA. Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disorders. Gene Ther. 2006;13:559-62.
-
(2006)
Gene Ther
, vol.13
, pp. 559-562
-
-
Campochiaro, P.A.1
-
209
-
-
32944481724
-
Adenoviral vector-delivered pigment epithelium-derived factor for neo-vascular age-related macular degeneration: Results of a phase I clinical trial
-
Campochiaro PA, Nguyen QD, Shah SM, Klein ML, Holz E, Frank RN, Saperstein DA, Gupta A, Stout JT, Macko J, DiBartolomeo R, Wei LL. Adenoviral vector-delivered pigment epithelium-derived factor for neo-vascular age-related macular degeneration: results of a phase I clinical trial. Hum Gene Ther. 2006;17:167-76.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 167-176
-
-
Campochiaro, P.A.1
Nguyen, Q.D.2
Shah, S.M.3
Klein, M.L.4
Holz, E.5
Frank, R.N.6
Saperstein, D.A.7
Gupta, A.8
Stout, J.T.9
Macko, J.10
DiBartolomeo, R.11
Wei, L.L.12
-
210
-
-
31644447744
-
Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir
-
Chevez-Barrios P, Chintagumpala M, Mieler W, Paysse E, Boniuk M, Kozinetz C, Hurwitz MY, Hurwitz RL. Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir. J Clin Oncol. 2005;23:7927-35.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7927-7935
-
-
Chevez-Barrios, P.1
Chintagumpala, M.2
Mieler, W.3
Paysse, E.4
Boniuk, M.5
Kozinetz, C.6
Hurwitz, M.Y.7
Hurwitz, R.L.8
-
211
-
-
33748117817
-
Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD
-
Cashman SM, Bowman L, Christofferson J, Kumar-Singh R. Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD. Invest Ophthalmol Vis Sci. 2006;47:3496-504.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 3496-3504
-
-
Cashman, S.M.1
Bowman, L.2
Christofferson, J.3
Kumar-Singh, R.4
-
212
-
-
27744448125
-
Wound healing and its impairment in the diabetic foot
-
Falanga V. Wound healing and its impairment in the diabetic foot. Lancet. 2005;366:1736-43.
-
(2005)
Lancet
, vol.366
, pp. 1736-1743
-
-
Falanga, V.1
-
213
-
-
0033016846
-
Incidence, outcomes, and cost of foot ulcers in patients with diabetes
-
Ramsey SD, Newton K, Blough D, McCulloch DK, Sandhu N, Reiber GE, Wagner EH. Incidence, outcomes, and cost of foot ulcers in patients with diabetes. Diabetes Care. 1999;22:382-7.
-
(1999)
Diabetes Care
, vol.22
, pp. 382-387
-
-
Ramsey, S.D.1
Newton, K.2
Blough, D.3
McCulloch, D.K.4
Sandhu, N.5
Reiber, G.E.6
Wagner, E.H.7
-
214
-
-
33748758740
-
Vascular endothelial growth factor-C accelerates diabetic wound healing
-
Saaristo A, Tammela T, Farkkila A, Karkkainen M, Suominen E, Yla-Herttuala S, Alitalo K. Vascular endothelial growth factor-C accelerates diabetic wound healing. Am J Pathol. 2006;169:1080-7.
-
(2006)
Am J Pathol
, vol.169
, pp. 1080-1087
-
-
Saaristo, A.1
Tammela, T.2
Farkkila, A.3
Karkkainen, M.4
Suominen, E.5
Yla-Herttuala, S.6
Alitalo, K.7
-
215
-
-
34447325570
-
Placenta growth factor in diabetic wound healing: Altered expression and therapeutic potential
-
Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal PM, Pesce M, Capogrossi MC, Failla CM, Napolitano M, Odorisio T. Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential. Am J Pathol. 2006;169:1167-82.
-
(2006)
Am J Pathol
, vol.169
, pp. 1167-1182
-
-
Cianfarani, F.1
Zambruno, G.2
Brogelli, L.3
Sera, F.4
Lacal, P.M.5
Pesce, M.6
Capogrossi, M.C.7
Failla, C.M.8
Napolitano, M.9
Odorisio, T.10
-
216
-
-
33645508703
-
COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model
-
Cho CH, Sung HK, Kim KT, Cheon HG, Oh GT, Hong HJ, Yoo OJ, Koh GY. COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci U S A. 2006;103:4946-51.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 4946-4951
-
-
Cho, C.H.1
Sung, H.K.2
Kim, K.T.3
Cheon, H.G.4
Oh, G.T.5
Hong, H.J.6
Yoo, O.J.7
Koh, G.Y.8
-
217
-
-
44449157228
-
Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression
-
Bitto A, Minutoli L, Galeano MR, Altavilla D, Polito F, Fiumara T, Calo M, Lo Cascio P, Zentilin L, Giacca M, Squadrito F. Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression. Clin Sci (Lond). 2008;114:707-18.
-
(2008)
Clin Sci (Lond)
, vol.114
, pp. 707-718
-
-
Bitto, A.1
Minutoli, L.2
Galeano, M.R.3
Altavilla, D.4
Polito, F.5
Fiumara, T.6
Calo, M.7
Lo Cascio, P.8
Zentilin, L.9
Giacca, M.10
Squadrito, F.11
-
218
-
-
4644250654
-
Electroporatic delivery of TGF-beta1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice
-
Lee PY, Chesnoy S, Huang L. Electroporatic delivery of TGF-beta1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice. J Invest Dermatol. 2004;123:791-8.
-
(2004)
J Invest Dermatol
, vol.123
, pp. 791-798
-
-
Lee, P.Y.1
Chesnoy, S.2
Huang, L.3
-
219
-
-
0037336442
-
Intradermal injection of transforming growth factor-beta1 gene enhances wound healing in genetically diabetic mice
-
Chesnoy S, Lee PY, Huang L. Intradermal injection of transforming growth factor-beta1 gene enhances wound healing in genetically diabetic mice. Pharm Res. 2003;20:345-50.
-
(2003)
Pharm Res
, vol.20
, pp. 345-350
-
-
Chesnoy, S.1
Lee, P.Y.2
Huang, L.3
-
220
-
-
0034476928
-
Adenoviral-mediated gene transfer in wound healing
-
Crombleholme TM. Adenoviral-mediated gene transfer in wound healing. Wound Repair Regen. 2000;8:460-72.
-
(2000)
Wound Repair Regen
, vol.8
, pp. 460-472
-
-
Crombleholme, T.M.1
-
221
-
-
21244435687
-
Lentiviral gene therapy with platelet-derived growth factor B sustains accelerated healing of diabetic wounds over time
-
Man LX, Park JC, Terry MJ, Mason JM, Burrell WA, Liu F, Kimball BY, Moorji SM, Lee JA, Breitbart AS. Lentiviral gene therapy with platelet-derived growth factor B sustains accelerated healing of diabetic wounds over time. Ann Plast Surg. 2005;55:81-6.
-
(2005)
Ann Plast Surg
, vol.55
, pp. 81-86
-
-
Man, L.X.1
Park, J.C.2
Terry, M.J.3
Mason, J.M.4
Burrell, W.A.5
Liu, F.6
Kimball, B.Y.7
Moorji, S.M.8
Lee, J.A.9
Breitbart, A.S.10
-
222
-
-
4744351350
-
Adenoviral mediated gene transfer of PDGF-B enhances wound healing in type I and type II diabetic wounds
-
Keswani SG, Katz AB, Lim FY, Zoltick P, Radu A, Alaee D, Herlyn M, Crombleholme TM. Adenoviral mediated gene transfer of PDGF-B enhances wound healing in type I and type II diabetic wounds. Wound Repair Regen. 2004;12:497-504.
-
(2004)
Wound Repair Regen
, vol.12
, pp. 497-504
-
-
Keswani, S.G.1
Katz, A.B.2
Lim, F.Y.3
Zoltick, P.4
Radu, A.5
Alaee, D.6
Herlyn, M.7
Crombleholme, T.M.8
-
223
-
-
35248846610
-
Lentiviral gene transfer of SDF-1 alpha to wounds improves diabetic wound healing
-
Badillo AT, Chung S, Zhang L, Zoltick P, Liechty KW. Lentiviral gene transfer of SDF-1 alpha to wounds improves diabetic wound healing. J Surg Res. 2007;143:35-42.
-
(2007)
J Surg Res
, vol.143
, pp. 35-42
-
-
Badillo, A.T.1
Chung, S.2
Zhang, L.3
Zoltick, P.4
Liechty, K.W.5
-
224
-
-
11144330922
-
Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model
-
Marti G, Ferguson M, Wang J, Byrnes C, Dieb R, Qaiser R, Bonde P, Duncan MD, Harmon JW. Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model. Gene Ther. 2004;11:1780-5.
-
(2004)
Gene Ther
, vol.11
, pp. 1780-1785
-
-
Marti, G.1
Ferguson, M.2
Wang, J.3
Byrnes, C.4
Dieb, R.5
Qaiser, R.6
Bonde, P.7
Duncan, M.D.8
Harmon, J.W.9
-
225
-
-
33744466786
-
Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling
-
Asai J, Takenaka H, Kusano KF, Ii M, Luedemann C, Curry C, Eaton E, Iwakura A, Tsutsumi Y, Hamada H, Kishimoto S, Thorne T, Kishore R, Losordo DW. Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling. Circulation. 2006;113:2413-24.
-
(2006)
Circulation
, vol.113
, pp. 2413-2424
-
-
Asai, J.1
Takenaka, H.2
Kusano, K.F.3
Ii, M.4
Luedemann, C.5
Curry, C.6
Eaton, E.7
Iwakura, A.8
Tsutsumi, Y.9
Hamada, H.10
Kishimoto, S.11
Thorne, T.12
Kishore, R.13
Losordo, D.W.14
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