-
4
-
-
0031742518
-
Prospects for gene therapy of insulin-dependent diabetes mellitus
-
(1998)
Diabetologia
, vol.41
, pp. 1401-1409
-
-
Efrat, S.1
-
6
-
-
0020696373
-
Effects of aging on the regenerative capacity of the pancreatic β-cell of the rat
-
(1983)
Diabetes
, vol.32
, pp. 14-19
-
-
Swenne, I.1
-
8
-
-
0034100823
-
Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
-
(2000)
Nat. Med.
, vol.6
, pp. 278-282
-
-
Ramiya, V.K.1
-
11
-
-
0030912531
-
Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2100-2109
-
-
Rafaeloff, R.1
-
12
-
-
0031985552
-
Culture of adult human islet preparations with heparocyte growth factor and 804G matrix is mitogenic for duct cells but not for β-cells
-
(1998)
Diabetes
, vol.47
, pp. 134-137
-
-
Lefebvre, V.H.1
-
17
-
-
0029944291
-
Induction and involvement of endogenous IGF-I in pancreas regeneration after partial pancreatectomy in the dog
-
(1996)
J. Endocrinol.
, vol.149
, pp. 259-267
-
-
Hayakawa, H.1
-
19
-
-
0032841435
-
Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signaling
-
(1999)
Nat. Genet.
, vol.23
, pp. 32-40
-
-
Wirhers, D.J.1
-
20
-
-
0032504211
-
Insulin-like growth facror I (IGF-I)-stimulated pancreatic β-cell growth is glucose-dependent: Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in Ins-1 cells
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17771-17779
-
-
Hügl, S.R.1
White, M.F.2
Rhodes, C.J.3
-
21
-
-
0028036698
-
S6K signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28783-28789
-
-
Myers, M.G.1
-
22
-
-
0031053586
-
Regulation of neuronal survival by the serine-thre-onine protein kinase Akt
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
-
23
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
(1997)
Genes Dev.
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
-
25
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
-
26
-
-
0032827420
-
Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7203-7215
-
-
Peruzzi, F.1
-
27
-
-
0030730904
-
Insulin-like growth factor I reverses interleukin-1β inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoprosis in rat islets of Langerhans
-
(1997)
FEBS Lett.
, vol.417
, pp. 235-238
-
-
Mabley, J.G.1
Belin, V.2
John, N.3
Green, I.C.4
-
28
-
-
0032544722
-
Growth factor protection against cytokine-induced apoptosis in neonatal rat islets of Langerhans: Role of Fas
-
(1998)
FEBS Lett.
, vol.435
, pp. 207-210
-
-
Harrison, M.1
-
29
-
-
0033969128
-
Inhibitory effect of IGF-I on type 2 nitric oxyde synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: Involvement of phosphatidylinositol 3-kinase
-
(2000)
Diabetes
, vol.49
, pp. 209-217
-
-
Castrillo, A.1
Bodelón, O.G.2
Boscá, L.3
-
30
-
-
0034509569
-
Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I
-
(2000)
Gene Ther
, vol.7
, pp. 2015-2022
-
-
Giannoukakis, N.1
-
34
-
-
0028073946
-
Expression of Glut-2 antisense RNA in β-cells of transgenic mice leads to diabetes
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28543-28546
-
-
Valera, A.1
-
40
-
-
0033011114
-
Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozotocin
-
(1999)
Nat. Med.
, vol.5
, pp. 314-319
-
-
Burkart, V.1
-
42
-
-
0019976376
-
The role of glucose in the in vitro regulation of cell cycle kinetics and proliferation of fetal pancrearic B-cells
-
(1982)
Diabetes
, vol.31
, pp. 754-760
-
-
Swenne, I.1
-
46
-
-
0034063375
-
Transgenic mice overexpressing insulin-like growth factor II in β-cells develop type 2 diabetes
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 731-740
-
-
Devedjian, J.C.1
-
47
-
-
0024234787
-
Growth enhancement of transgenic mice expressing human insulin-like growth factor I
-
(1988)
Endocrinology
, vol.123
, pp. 2827-2833
-
-
Mathews, L.S.1
-
48
-
-
0024507405
-
Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice
-
(1989)
Endocrinology
, vol.124
, pp. 40-48
-
-
Quaife, C.J.1
-
49
-
-
0020470466
-
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes
-
(1982)
Nature
, vol.300
, pp. 611-615
-
-
Palmiter, R.D.1
-
50
-
-
0023751235
-
Tissue-specific expression and dietary regulation of a chimeric phosphoeneolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 11443-11451
-
-
McGrane, M.M.1
-
52
-
-
0027231548
-
Glucose metabolism in transgenic mice containing a chimeric P-enolpyruvate carboxykinase/bovine growth hormone gene
-
(1993)
FASEB J.
, vol.7
, pp. 791-800
-
-
Valera, A.1
-
53
-
-
0032567937
-
Disruption of IRS-2 causes type 2-diabetes
-
(1998)
Nature
, vol.391
, pp. 900-903
-
-
Withers, D.J.1
-
54
-
-
0034781057
-
Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha
-
(2001)
Nat. Med.
, vol.7
, pp. 1133-1137
-
-
Turtle, R.L.1
-
56
-
-
0034700456
-
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice
-
(2000)
Nature
, vol.408
, pp. 994-997
-
-
Pende, M.1
-
60
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
-
(1997)
Cell
, vol.21
, pp. 561-572
-
-
Bruning, J.C.1
-
64
-
-
0032932822
-
Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3278-3288
-
-
Frasca, F.1
|