Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice

Diabetes

Volumn 52, Issue 3, 2003, Pages 708-716

  Zhang, Y Clare ^a   Pileggi, Antonello ^b   Agarwal, Anupam ^c   Molano, R Damaris ^b   Powers, Matthew ^a   Brusko, Todd ^a   Wasserfall, Clive ^a   Goudy, Kevin ^a   Zahr, Elsie ^b   Poggioli, Raffaella ^b   Scott Jorgensen, Marda ^a   Campbell Thompson, Martha ^a   Crawford, James M ^a   Nick, Harry ^c   Flotte, Terence ^a,c   Ellis, Tamir M ^a   Ricordi, Camillo ^b   Inverardi, Luca ^b   Atkinson, Mark A ^a,c  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

GFP, green fluorescent protein; HO 1, heme oxygenase 1; IFN , interferon; IU, infectious units; LPS, lipopolysaccharide; RAAV, recombinant adeno associated virus; SOD, superoxide dismutase

Indexed keywords

ADENOVIRUS VECTOR; ANTIOXIDANT; GREEN FLUORESCENT PROTEIN; HEME OXYGENASE 1; MANGANESE SUPEROXIDE DISMUTASE; RECOMBINANT INTERLEUKIN 10;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MECHANISM; GRAFT SURVIVAL; IMMUNOREGULATION; INSULIN DEPENDENT DIABETES MELLITUS; ISOGRAFT; ISOTRANSPLANTATION; KIDNEY CAPSULE; LYMPHOCYTIC INFILTRATION; MOUSE; MOUSE STRAIN; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RECURRENT DISEASE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; AUTOIMMUNITY; DEPENDOVIRUS; DIABETES MELLITUS, TYPE 1; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GRAFT SURVIVAL; GREEN FLUORESCENT PROTEINS; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; INFLAMMATION; INTERLEUKIN-10; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LUMINESCENT PROTEINS; LYMPHOCYTES; MEMBRANE PROTEINS; MICE; MICE, INBRED NOD; MUSCLE, SKELETAL; RECURRENCE; SUPEROXIDE DISMUTASE;

EID: 0344642932     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.3.708     Document Type: Article

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