메뉴 건너뛰기




Volumn 111, Issue 9, 2003, Pages 1357-1363

Transfer of hematopoietic stem cells encoding autoantigen autoanfigen prevents autoimmune diabetes

Author keywords

[No Author keywords available]

Indexed keywords

PROINSULIN;

EID: 0038326717     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI15995     Document Type: Article
Times cited : (99)

References (42)
  • 1
    • 0036464664 scopus 로고    scopus 로고
    • Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: Getting closer to a cure?
    • Burt, R.K., Slavin, S., Burns, W.H., and Matmont A.M. 2002. Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: getting closer to a cure? Blood. 99:768-784.
    • (2002) Blood , vol.99 , pp. 768-784
    • Burt, R.K.1    Slavin, S.2    Burns, W.H.3    Matmont, A.M.4
  • 2
    • 0344338626 scopus 로고
    • Prevention of type 1 diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation
    • Ikehara, S., et al. 1985. Prevention of type 1 diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation. Proc. Natl. Acad. Sci. U. S. A 82:7743-7747.
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 7743-7747
    • Ikehara, S.1
  • 3
    • 0024830841 scopus 로고
    • Reciprocal allogeneic bone marrow transplantation between NOD mice and diabetes-nonsusceptible mice associated with transfer and prevention of autoimmune diabetes
    • LaFace, D.M., and Peck, A.B. 1989. Reciprocal allogeneic bone marrow transplantation between NOD mice and diabetes-nonsusceptible mice associated with transfer and prevention of autoimmune diabetes. Diabetes. 38:894-901.
    • (1989) Diabetes , vol.38 , pp. 894-901
    • LaFace, D.M.1    Peck, A.B.2
  • 4
    • 0034721490 scopus 로고    scopus 로고
    • Successful prevention of autoimmune disease by transplantation of adequate number of fully altogeneic hematopoietic stem cells
    • El-Badri, N.S., et al. 2000. Successful prevention of autoimmune disease by transplantation of adequate number of fully altogeneic hematopoietic stem cells. Transplantation. 70:870-877.
    • (2000) Transplantation , vol.70 , pp. 870-877
    • El-Badri, N.S.1
  • 5
    • 0024121537 scopus 로고
    • Marrow transplantation from tolerant donors to treat and prevent autoimmune diseases in BXSB mice
    • Himeno, K., and Good, R.A. 1988. Marrow transplantation from tolerant donors to treat and prevent autoimmune diseases in BXSB mice. Proc. Natl. Acad. Sci U. S. A. 85:2235-2239.
    • (1988) Proc. Natl. Acad. Sci U. S. A. , vol.85 , pp. 2235-2239
    • Himeno, K.1    Good, R.A.2
  • 6
    • 0034571956 scopus 로고    scopus 로고
    • Prevention of coronary vascular disease by transplantation of T-cell-depleted bone marrow and hematopoietic stem cell preparation in autoimmune-prone w/BF(1) mice
    • Kirzner, R.P., Engelman, R.W., Mizutani, H., Specter, S., and Good, R.A. 2000. Prevention of coronary vascular disease by transplantation of T-cell-depleted bone marrow and hematopoietic stem cell preparation in autoimmune-prone w/BF(1) mice. Biol. Blood Marrow Transplant. 6:513-522.
    • (2000) Biol. Blood Marrow Transplant , vol.6 , pp. 513-522
    • Kirzner, R.P.1    Engelman, R.W.2    Mizutani, H.3    Specter, S.4    Good, R.A.5
  • 7
    • 0029671326 scopus 로고    scopus 로고
    • Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice
    • Li, H., et al. 1996. Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice. J. Immunol. 156:380-388.
    • (1996) J. Immunol. , vol.156 , pp. 380-388
    • Li, H.1
  • 8
    • 0031091740 scopus 로고    scopus 로고
    • Patterns of hemopoietic reconstitution in nonobese diabetic mice: Dichotomy of allogeneic resistance versus competitive advantage of disease-resistant marrow
    • Kaufman, C.L., Li, H., and Ildstad, S.T. 1997. Patterns of hemopoietic reconstitution in nonobese diabetic mice: dichotomy of allogeneic resistance versus competitive advantage of disease-resistant marrow. J. Immunol. 158:2435-2442.
    • (1997) J. Immunol. , vol.158 , pp. 2435-2442
    • Kaufman, C.L.1    Li, H.2    Ildstad, S.T.3
  • 9
    • 0037085746 scopus 로고    scopus 로고
    • Unrelated donot marrow transplantation for myelodysplastic syndromes: Outcome analysis in 510 transplants facilitated by the National Marrow Donor Program
    • Castro-Malaspina, H., et al. 2002. Unrelated donot marrow transplantation for myelodysplastic syndromes: outcome analysis in 510 transplants facilitated by the National Marrow Donor Program. Blood. 99:1943-1951.
    • (2002) Blood , vol.99 , pp. 1943-1951
    • Castro-Malaspina, H.1
  • 11
    • 0026593440 scopus 로고
    • Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens
    • Eynon, E.E., and Parker, D.C. 1992. Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens. J. Exp. Med. 175:131-138.
    • (1992) J. Exp. Med. , vol.175 , pp. 131-138
    • Eynon, E.E.1    Parker, D.C.2
  • 12
    • 0032573712 scopus 로고    scopus 로고
    • Donor resting B cells induce indefinite prolongation of fuUy allogeneic cardiac grafts when delivered with anti-immunoglobulin-D monoclonal antibody: Evidence for tolerogenicity of donor resting B cells in vivo
    • Niimi, M., Hara, M., Witzke, O., Morris, P.J., and Wood, K.J. 1998 Donor resting B cells induce indefinite prolongation of fuUy allogeneic cardiac grafts when delivered with anti-immunoglobulin-D monoclonal antibody: evidence for tolerogenicity of donor resting B cells in vivo. Transplantation. 66:1786-1792.
    • (1998) Transplantation , vol.66 , pp. 1786-1792
    • Niimi, M.1    Hara, M.2    Witzke, O.3    Morris, P.J.4    Wood, K.J.5
  • 13
    • 0030586611 scopus 로고    scopus 로고
    • Dendritic cells can present antigen in vivo in either a tolerogenic or immunogenic fashion
    • Finkelman, F.D., Lees, A., Birnbaum, R, Gause, W.C., and Morris, S.C. 1996. Dendritic cells can present antigen in vivo in either a tolerogenic or immunogenic fashion. J. Immunol. 157:1406-1414.
    • (1996) J. Immunol. , vol.157 , pp. 1406-1414
    • Finkelman, F.D.1    Lees, A.2    Birnbaum, R.3    Gause, W.C.4    Morris, S.C.5
  • 14
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger, D., et al. 2001. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 194:769-779.
    • (2001) J. Exp. Med. , vol.194 , pp. 769-779
    • Hawiger, D.1
  • 16
    • 0033981213 scopus 로고    scopus 로고
    • Gamma delta T cells as mediators of mucosal tolerance: The autoimmune diabetes model
    • Hänninen, A., and Harrison, L.C. 2000. Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model. Immunol. Rev. 173:109-119.
    • (2000) Immunol. Rev. , vol.173 , pp. 109-119
    • Hänninen, A.1    Harrison, L.C.2
  • 17
    • 0038826958 scopus 로고    scopus 로고
    • Proinsulin - A pathogenic autoantigen in type 1 diabetes
    • In press
    • Narendran, P., Manneting, S., and Harrison, L.C. 2003. Proinsulin - a pathogenic autoantigen in type 1 diabetes. Autoimmun. Rev. In press.
    • (2003) Autoimmun. Rev.
    • Narendran, P.1    Manneting, S.2    Harrison, L.C.3
  • 18
    • 0031025574 scopus 로고    scopus 로고
    • Transgenic expression of mouse proinsulin 11 prevents diabetes in nonobese diabetic mice
    • French, M.B., et al. 1997. Transgenic expression of mouse proinsulin 11 prevents diabetes in nonobese diabetic mice. Diabetes. 46:34-39.
    • (1997) Diabetes , vol.46 , pp. 34-39
    • French, M.B.1
  • 19
    • 0037093840 scopus 로고    scopus 로고
    • Increased generation of dendritic cells from myetoid progenitors in autoimmune-prone nonobese diabetic mice
    • Steptoe, R.J., Ritchie, J.M., and Harrison, L.C. 2002. Increased generation of dendritic cells from myetoid progenitors in autoimmune-prone nonobese diabetic mice. J. Immunol. 168:5032-5041.
    • (2002) J. Immunol. , vol.168 , pp. 5032-5041
    • Steptoe, R.J.1    Ritchie, J.M.2    Harrison, L.C.3
  • 20
    • 0020024396 scopus 로고
    • Multiple low-dose streptozorocin-induced hyperglycemia and insulitis in C57BL mice: Influence of inbred background, sex and thymus
    • Leiter, E.H. 1982. Multiple low-dose streptozorocin-induced hyperglycemia and insulitis in C57BL mice: influence of inbred background, sex and thymus. Proc. Natl. Acad. Sci. U. S. A. 79:630-634.
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , pp. 630-634
    • Leiter, E.H.1
  • 21
    • 0028914351 scopus 로고
    • Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
    • Daniel, D., Gill, R.G., Schloot, N., and Wegmann, D. 1995. Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice. Eur. J. Immunol. 25:1056-1062.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1056-1062
    • Daniel, D.1    Gill, R.G.2    Schloot, N.3    Wegmann, D.4
  • 22
    • 0035500757 scopus 로고    scopus 로고
    • Evidence that a peptide spanning the B-C junction of proinsulin is an early autoantigen epitope in the pathogenesis of type 1 diabetes
    • Chen, W., et al. 2001. Evidence that a peptide spanning the B-C junction of proinsulin is an early autoantigen epitope in the pathogenesis of type 1 diabetes. J. Immunol. 167:4926-4935.
    • (2001) J. Immunol. , vol.167 , pp. 4926-4935
    • Chen, W.1
  • 23
    • 0035511862 scopus 로고    scopus 로고
    • International workshop on lessons from animal models for human type 1 diabetes: Identification of insulin but nor glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice
    • Bonifacio, E., et al. 2001. International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: Identification of insulin but nor glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice. Diabetes. 50:2451-2458.
    • (2001) Diabetes , vol.50 , pp. 2451-2458
    • Bonifacio, E.1
  • 24
    • 0026554156 scopus 로고
    • The nonobese diabetic scid mouse: Model for spontaneous thymomagenesis associated with immunodeficiency
    • Prochazka, M., Gaskins, H.R., Shultz, L.D., and Leiter, E.H. 1992. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proc. Natl. Acad. Sci. U. S. A. 89:3290-3294.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 3290-3294
    • Prochazka, M.1    Gaskins, H.R.2    Shultz, L.D.3    Leiter, E.H.4
  • 25
    • 0034144688 scopus 로고    scopus 로고
    • NOD/LtSz-Rag1null mice: An immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells
    • Shultz, L.D., et al. 2000. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J. Immunol. 164:2496-2507.
    • (2000) J. Immunol. , vol.164 , pp. 2496-2507
    • Shultz, L.D.1
  • 26
    • 0023829859 scopus 로고
    • NOD marrow stem cells adoptively transfer diabetes to resistant (NOD x NON) F1 mice
    • Serreze, D.V., Leiter, E.H., Worthen, S.M., and Shultz, L.D. 1988. NOD marrow stem cells adoptively transfer diabetes to resistant (NOD x NON) F1 mice. Diabetes. 37:252-255.
    • (1988) Diabetes , vol.37 , pp. 252-255
    • Serreze, D.V.1    Leiter, E.H.2    Worthen, S.M.3    Shultz, L.D.4
  • 27
    • 0023690453 scopus 로고
    • Expression of genetically determined diabetes and insulitis in the nonobese diabetic (NOD) mouse at the level of bone marrow-derived cells, transfer of diabetes and insulitis to nondiabetic (NOD x B10) F1 mice with bone marrow cells from NOD mice
    • Wicker, L.S., Miller, B.J., Chai, A., Terada, M., and Mullen, Y. 1988. Expression of genetically determined diabetes and insulitis in the nonobese diabetic (NOD) mouse at the level of bone marrow-derived cells, transfer of diabetes and insulitis to nondiabetic (NOD x B10) F1 mice with bone marrow cells from NOD mice. J. Exp. Med. 167:1801-1810.
    • (1988) J. Exp. Med. , vol.167 , pp. 1801-1810
    • Wicker, L.S.1    Miller, B.J.2    Chai, A.3    Terada, M.4    Mullen, Y.5
  • 28
    • 0028859072 scopus 로고
    • Induction of mixed bone marrow chimerism as potential therapy for autoimmune (type I) diabetes: Experience in the NOD model
    • Mathieu, C., Bouillon, R, Rurgeerts, O., and Waer, M. 1995. Induction of mixed bone marrow chimerism as potential therapy for autoimmune (type I) diabetes: experience in the NOD model. Transplant. Proc. 27:640-641.
    • (1995) Transplant. Proc. , vol.27 , pp. 640-641
    • Mathieu, C.1    Bouillon, R.2    Rurgeerts, O.3    Waer, M.4
  • 29
    • 0029360443 scopus 로고
    • Similar peptides from two beta cell autoantigens, proinsulin and glummic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes
    • Rudy, G., et al. 1995. Similar peptides from two beta cell autoantigens, proinsulin and glummic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes. Mol. Med. 1:625-633.
    • (1995) Mol. Med. , vol.1 , pp. 625-633
    • Rudy, G.1
  • 30
    • 0032584240 scopus 로고    scopus 로고
    • T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin
    • Congia, M., Patel, S., Cope, A.P., De Virgilis, S., and Sonderstrup, G. 1998. T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin. Proc. Natl. Acad. Sci. U. S. A. 95:3833-3838.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 3833-3838
    • Congia, M.1    Patel, S.2    Cope, A.P.3    De Virgilis, S.4    Sonderstrup, G.5
  • 31
    • 0037006432 scopus 로고    scopus 로고
    • Predominantly recognised proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity
    • Durinovic-Bello, I. Boehm, B., and Ziegler, A.-G. 2002. Predominantly recognised proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity. J. Autoimmun. 18:55-66.
    • (2002) J. Autoimmun. , vol.18 , pp. 55-66
    • Durinovic-Bello, I.1    Boehm, B.2    Ziegler, A.-G.3
  • 32
    • 0038814318 scopus 로고    scopus 로고
    • Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide
    • doi:10.1172/JCI200317166
    • Martinez, N.R., et al. 2003. Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide. J. Clin. Invest. 111:1365-1371. doi:10.1172/JCI200317166.
    • (2003) J. Clin. Invest. , vol.111 , pp. 1365-1371
    • Martinez, N.R.1
  • 33
    • 0034608389 scopus 로고    scopus 로고
    • Role of antigen-presenting cells in mediating tolerance and aumimmunity
    • Garza, K.M., et al. 2000. Role of antigen-presenting cells in mediating tolerance and aumimmunity. J. Exp. Med. 191:2021-2027.
    • (2000) J. Exp. Med. , vol.191 , pp. 2021-2027
    • Garza, K.M.1
  • 34
    • 0035575992 scopus 로고    scopus 로고
    • Tolerance or immunity to a tumor antigen expressed in somatic cells can be determined by systemic ptoinflammatory signals at the time of first antigen exposure
    • Frazet, I.H., et al. 2001. Tolerance or immunity to a tumor antigen expressed in somatic cells can be determined by systemic ptoinflammatory signals at the time of first antigen exposure. J. Immunol 167:6180-6187.
    • (2001) J. Immunol. , vol.167 , pp. 6180-6187
    • Frazet, I.H.1
  • 35
    • 0031058466 scopus 로고    scopus 로고
    • Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo
    • Brocker, T., Riedinger, M., and Karjalainen, K. 1997. Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo. J. Exp. Med. 185:541-550.
    • (1997) J. Exp. Med. , vol.185 , pp. 541-550
    • Brocker, T.1    Riedinger, M.2    Karjalainen, K.3
  • 36
    • 0027368141 scopus 로고
    • Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
    • Kaufman, D.L., et al. 1993. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature. 366:69-72.
    • (1993) Nature , vol.366 , pp. 69-72
    • Kaufman, D.L.1
  • 37
    • 0027908753 scopus 로고
    • Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
    • Tisch, R., et al. 1993. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature. 366:72-75.
    • (1993) Nature , vol.366 , pp. 72-75
    • Tisch, R.1
  • 38
    • 0035512606 scopus 로고    scopus 로고
    • st international NOD mouse T-cell workshop and the follow-up mini-workshop
    • st International NOD Mouse T-cell Workshop and the follow-up Mini-Workshop. Diabetes. 50:2459-2463.
    • (2001) Diabetes , vol.50 , pp. 2459-2463
    • Kaufman, D.L.1
  • 39
    • 0035421176 scopus 로고    scopus 로고
    • Transient insulin autoantibody expression independent of development of diabetes: Comparison of NOD and NOR strains
    • Abiru, N., et al. 2001. Transient insulin autoantibody expression independent of development of diabetes: comparison of NOD and NOR strains. J. Autoimmun. 17:1-6.
    • (2001) J. Autoimmun. , vol.17 , pp. 1-6
    • Abiru, N.1
  • 40
    • 0034967803 scopus 로고    scopus 로고
    • Risk assessment, prediction and prevention of type 1 diabetes
    • Harrison, L.C. 2001. Risk assessment, prediction and prevention of type 1 diabetes. Pediatr. Diabetes 2:71-82.
    • (2001) Pediatr. Diabetes , vol.2 , pp. 71-82
    • Harrison, L.C.1
  • 41
    • 0031053834 scopus 로고    scopus 로고
    • Stem cell transplantation in the normal nonmyeloablated host: Relationship between cell dose, schedule and engraftment
    • Rao, S., et al. 1997. Stem cell transplantation in the normal nonmyeloablated host: relationship between cell dose, schedule and engraftment. Exp. Hematol. 25:114-121.
    • (1997) Exp. Hematol. , vol.25 , pp. 114-121
    • Rao, S.1
  • 42
    • 0037079725 scopus 로고    scopus 로고
    • Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced human hematopoietic stem/progenitor cells
    • Cui, Y., et al. 2002. Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced human hematopoietic stem/progenitor cells. Blood. 99:399-408.
    • (2002) Blood , vol.99 , pp. 399-408
    • Cui, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.