Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I

Gene Therapy

Volumn 7, Issue 23, 2000, Pages 2015-2022

  Giannoukakis, N ^a   Mi, Z ^a   Rudert, W A ^a   Gambotto, A ^a   Trucco, M ^a   Robbins, P ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Adenovirus; Gene therapy; IGF I; IL 1 ; Islets

Indexed keywords

BETA GALACTOSIDASE; CYTOKINE; FAS ANTIGEN; GLUCOSE; GREEN FLUORESCENT PROTEIN; INHIBITOR PROTEIN; INSULIN; INTERLEUKIN 1BETA; NITRIC OXIDE; SOMATOMEDIN C; VIRUS VECTOR;

ADENOVIRUS; APOPTOSIS; ARTICLE; CELL DESTRUCTION; CELL SURVIVAL; CONTROLLED STUDY; GENE TRANSFER; GENETIC CODE; HUMAN; HUMAN CELL; HYPOTHESIS; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PANCREAS ISLET DISEASE; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT;

ADENOVIRIDAE; ANALYSIS OF VARIANCE; APOPTOSIS; BETA-GALACTOSIDASE; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GLUCOSE; GREEN FLUORESCENT PROTEINS; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-1; ISLETS OF LANGERHANS; LUMINESCENT PROTEINS; NITRIC OXIDE; TRANSFECTION;

EID: 0034509569     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301333     Document Type: Article

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