Control of regulatory T cell development by the transcription factor Foxp3

Science

Volumn 299, Issue 5609, 2003, Pages 1057-1061

  Hori, Shohei ^a   Nomura, Takashi ^b   Sakaguchi, Shimon ^a,b  

^a Institute of Physical and Chemical Research   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENE TRANSFER;

TRANSCRIPTION FACTORS;

IMMUNOLOGY;

CD4 ANTIGEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

GENE; IMMUNE RESPONSE; MICROBIOLOGY;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL MATURATION; CONTROLLED STUDY; GENE CONTROL; GENE TRANSFER; GENETIC CODE; HUMAN; HUMAN CELL; INFLAMMATION; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GASTRITIS; IMMUNE TOLERANCE; INFLAMMATORY BOWEL DISEASES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, SCID; MICE, TRANSGENIC; MUTATION; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-2; RECOMBINANT FUSION PROTEINS; SELF TOLERANCE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND; TRANSDUCTION, GENETIC;

ANIMALIA;

EID: 0347785480     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1079490     Document Type: Article

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33. We thank K. J. Wood, Z. Fehervari, and T. Takahashi for critically reading the manuscript; W. S. Pear and T. Kitamura for reagents; and T. Matsushita for histology. Supported by grants-in-aid from the Ministry of Education, Sports and Culture, the Ministry of Human Welfare, and the Organization for Pharmaceutical Safety and Research of Japan.