Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue

Nature

Volumn 408, Issue 6811, 2000, Pages 483-488

  Lee, Hyun Chul ^a   Kim, Su Jin ^a   Kim, Kyung Sup ^b   Shin, Hang Cheol ^a   Yoon, Ji Won ^a,c  

^a Department of Internal Medicine   (South Korea)

^b Yonsei University   (South Korea)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; COMPLEMENTARY DNA; GLUCOSE; INSULIN DERIVATIVE; MESSENGER RNA; PLASMID DNA; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; GENE THERAPY; GLUCOSE BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; VIRUS RECOMBINANT;

ANIMALS; BASE SEQUENCE; BLOOD GLUCOSE; CLONING, MOLECULAR; DEPENDOVIRUS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DNA, COMPLEMENTARY; DNA, RECOMBINANT; ESCHERICHIA COLI; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GLUCOSE TOLERANCE TEST; HALF-LIFE; HEPATOCYTES; INSULIN; LIVER; MALE; MICE; MICE, INBRED NOD; MOLECULAR SEQUENCE DATA; PLASMIDS; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY;

ADENO-ASSOCIATED VIRUS; ANIMALIA; SIA;

EID: 0034707028     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35044106     Document Type: Article

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