Constitutively active PDX1 induced efficient insulin production in adult murine liver

Biochemical and Biophysical Research Communications

Volumn 326, Issue 2, 2005, Pages 402-409

  Imai, Junta ^a   Katagiri, Hideki ^a   Yamada, Tetsuya ^a   Ishigaki, Yasushi ^a   Ogihara, Takehide ^a   Uno, Kenji ^a   Hasegawa, Yutaka ^a   Gao, Junhong ^a   Ishihara, Hisamitsu ^a   Sasano, Hironobu ^a   Mizuguchi, Hiroyuki ^b   Asano, Tomoichiro ^c   Oka, Yoshitomo ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Adenovirus; Diabetes; Gene therapy; Insulin; PDX1; Transdifferentiation

Indexed keywords

ADENOVIRUS VECTOR; ALBUMIN; RECOMBINANT PROTEIN; STREPTOZOCIN; TRANSCRIPTION FACTOR PDX 1; TRANSFERRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DRUG EFFECT; DRUG MECHANISM; GENE MUTATION; GENE TARGETING; INSULIN RELEASE; INTERMETHOD COMPARISON; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; WILD TYPE;

ADENOVIRIDAE; AGING; ALBUMINS; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; GENE THERAPY; HOMEODOMAIN PROTEINS; INSULIN; LIVER; MALE; MICE; TRANS-ACTIVATORS; TRANSFERRIN;

ADENOVIRIDAE; MURINAE;

EID: 9944235761     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.11.047     Document Type: Article

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