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Volumn 49, Issue 1, 2006, Pages 71-74

Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: Reduced insulin antibody titres and preserved beta cell function

Author keywords

Beta cell function; IDDM2; Insulin antibodies; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; C PEPTIDE; HEMOGLOBIN A1C; INSULIN; INSULIN ANTIBODY;

EID: 31444455001     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-0042-1     Document Type: Article
Times cited : (25)

References (16)
  • 1
    • 0016177620 scopus 로고
    • HL-A antigens and diabetes mellitus
    • Nerup J, Platz P, Andersen OO et al (1974) HL-A antigens and diabetes mellitus. Lancet 12:864-866
    • (1974) Lancet , vol.12 , pp. 864-866
    • Nerup, J.1    Platz, P.2    Andersen, O.O.3
  • 2
    • 0021343570 scopus 로고
    • A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus
    • Bell GI, Horita S, Karam JH (1984) A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 33:176-183
    • (1984) Diabetes , vol.33 , pp. 176-183
    • Bell, G.I.1    Horita, S.2    Karam, J.H.3
  • 3
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • Ueda H, Howson JM, Esposito L et al (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 29:506-511
    • (2003) Nature , vol.29 , pp. 506-511
    • Ueda, H.1    Howson, J.M.2    Esposito, L.3
  • 4
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
    • Bottini N, Musumeci L, Alonso A et al (2004) A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 36:337-338
    • (2004) Nat Genet , vol.36 , pp. 337-338
    • Bottini, N.1    Musumeci, L.2    Alonso, A.3
  • 5
    • 3042698329 scopus 로고    scopus 로고
    • Remapping the insulin gene/IDDM2 locus in type 1 diabetes
    • Barratt BJ, Payne F, Lowe CE et al (2004) Remapping the insulin gene/IDDM2 locus in type 1 diabetes. Diabetes 53:1884-1889
    • (2004) Diabetes , vol.53 , pp. 1884-1889
    • Barratt, B.J.1    Payne, F.2    Lowe, C.E.3
  • 6
    • 0031018819 scopus 로고    scopus 로고
    • Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
    • Vafiadis P, Bennett ST, Todd JA et al (1997) Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nat Genet 15:289-292
    • (1997) Nat Genet , vol.15 , pp. 289-292
    • Vafiadis, P.1    Bennett, S.T.2    Todd, J.A.3
  • 7
    • 0028881617 scopus 로고
    • The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription
    • Kennedy GC, German MS, Rutter WJ (1995) The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. Nat Genet 9:293-298
    • (1995) Nat Genet , vol.9 , pp. 293-298
    • Kennedy, G.C.1    German, M.S.2    Rutter, W.J.3
  • 8
    • 0033959416 scopus 로고    scopus 로고
    • Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles
    • Huxtable SJ, Saker PJ, Haddad L et al (2000). Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles. Diabetes 49:126-130
    • (2000) Diabetes , vol.49 , pp. 126-130
    • Huxtable, S.J.1    Saker, P.J.2    Haddad, L.3
  • 9
    • 0012853951 scopus 로고    scopus 로고
    • Genomic analysis of the human MHC. DNA based typing for HLA alleles and linked polymorphisms
    • MGJ Tilanus (ed) International Histocompatibility Working Group
    • Genomic analysis of the human MHC. DNA based typing for HLA alleles and linked polymorphisms. In: MGJ Tilanus (ed) IHWG Technical Manual. International Histocompatibility Working Group. Available at http://www.ihwg.org/shared/tm2. htm
    • IHWG Technical Manual
  • 11
    • 0036319041 scopus 로고    scopus 로고
    • Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes
    • Diabetes Incidence in Sweden Study Group; Swedish Childhood Diabetes Study Group
    • Graham J, Hagopian WA, Kockum I et al (2002) Diabetes Incidence in Sweden Study Group; Swedish Childhood Diabetes Study Group. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes 51:1346-1355
    • (2002) Diabetes , vol.51 , pp. 1346-1355
    • Graham, J.1    Hagopian, W.A.2    Kockum, I.3
  • 12
    • 24944506424 scopus 로고    scopus 로고
    • The effect of HLA class II, insulin and CTLA4 gene regions on development of humoral beta-cell autoimmunity
    • Hermann R, Laine A-P, Veijola R et al (2005) The effect of HLA class II, insulin and CTLA4 gene regions on development of humoral beta-cell autoimmunity. Diabetologia 48:1766-1775
    • (2005) Diabetologia , vol.48 , pp. 1766-1775
    • Hermann, R.1    Laine, A.-P.2    Veijola, R.3
  • 13
    • 0242351651 scopus 로고    scopus 로고
    • Insulin gene VNTR genotype is associated with insulin sensitivity and secretion in infancy
    • Oxf
    • Bazaes RA, Petry CJ, Ong KK et al (2003) Insulin gene VNTR genotype is associated with insulin sensitivity and secretion in infancy. Clin Endocrinol (Oxf) 59:599-603
    • (2003) Clin Endocrinol , vol.59 , pp. 599-603
    • Bazaes, R.A.1    Petry, C.J.2    Ong, K.K.3
  • 14
    • 1942470577 scopus 로고    scopus 로고
    • Polymorphism of INS VNTR is associated with glutamic acid decarboxylase antibodies and postprandial C-peptide in patients with onset of diabetes after 35 years of age
    • Matejkova-Behanova M, Vankova M, Hill M et al (2004) Polymorphism of INS VNTR is associated with glutamic acid decarboxylase antibodies and postprandial C-peptide in patients with onset of diabetes after 35 years of age. Physiol Res 53:187-190
    • (2004) Physiol Res , vol.53 , pp. 187-190
    • Matejkova-Behanova, M.1    Vankova, M.2    Hill, M.3
  • 15
    • 0026568387 scopus 로고
    • Central obesity and hyperinsulinaemia in women are associated with polymorphism in the 5′ flanking region of the human insulin gene
    • Weaver JU, Kopelman PG, Hitman GA (1992) Central obesity and hyperinsulinaemia in women are associated with polymorphism in the 5′ flanking region of the human insulin gene. Eur J Clin Invest 22:265-270
    • (1992) Eur J Clin Invest , vol.22 , pp. 265-270
    • Weaver, J.U.1    Kopelman, P.G.2    Hitman, G.A.3
  • 16
    • 0032724752 scopus 로고    scopus 로고
    • INS VNTR allelic variation and dynamic insulin secretion in healthy adult non-diabetic Caucasian subjects
    • Ahmed S, Bennett ST, Huxtable SJ et al (1999) INS VNTR allelic variation and dynamic insulin secretion in healthy adult non-diabetic Caucasian subjects. Diabet Med 16:910-917
    • (1999) Diabet Med , vol.16 , pp. 910-917
    • Ahmed, S.1    Bennett, S.T.2    Huxtable, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.