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Volumn 24, Issue 6, 2006, Pages 677-688

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17;

EID: 33744984785     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2006.06.002     Document Type: Review
Times cited : (1228)

References (103)
  • 1
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • Aggarwal S., Ghilardi N., Xie M.H., de Sauvage F.J., and Gurney A.L. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278 (2003) 1910-1914
    • (2003) J. Biol. Chem. , vol.278 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.H.3    de Sauvage, F.J.4    Gurney, A.L.5
  • 3
    • 0036839102 scopus 로고    scopus 로고
    • Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
    • Almeida A.R., Legrand N., Papiernik M., and Freitas A.A. Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J. Immunol. 169 (2002) 4850-4860
    • (2002) J. Immunol. , vol.169 , pp. 4850-4860
    • Almeida, A.R.1    Legrand, N.2    Papiernik, M.3    Freitas, A.A.4
  • 4
    • 2542420993 scopus 로고    scopus 로고
    • In vivo instruction of suppressor commitment in naive T cells
    • Apostolou I., and von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199 (2004) 1401-1408
    • (2004) J. Exp. Med. , vol.199 , pp. 1401-1408
    • Apostolou, I.1    von Boehmer, H.2
  • 5
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou I., Sarukhan A., Klein L., and von Boehmer H. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3 (2002) 756-763
    • (2002) Nat. Immunol. , vol.3 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    von Boehmer, H.4
  • 7
    • 0035920510 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
    • Bensinger S.J., Bandeira A., Jordan M.S., Caton A.J., and Laufer T.M. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells. J. Exp. Med. 194 (2001) 427-438
    • (2001) J. Exp. Med. , vol.194 , pp. 427-438
    • Bensinger, S.J.1    Bandeira, A.2    Jordan, M.S.3    Caton, A.J.4    Laufer, T.M.5
  • 8
    • 9644295708 scopus 로고    scopus 로고
    • Issues in T-helper 1 development--resolved and unresolved
    • Berenson L.S., Ota N., and Murphy K.M. Issues in T-helper 1 development--resolved and unresolved. Immunol. Rev. 202 (2004) 157-174
    • (2004) Immunol. Rev. , vol.202 , pp. 157-174
    • Berenson, L.S.1    Ota, N.2    Murphy, K.M.3
  • 9
    • 13244290058 scopus 로고    scopus 로고
    • IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together
    • Bettelli E., and Kuchroo V.K. IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together. J. Exp. Med. 201 (2005) 169-171
    • (2005) J. Exp. Med. , vol.201 , pp. 169-171
    • Bettelli, E.1    Kuchroo, V.K.2
  • 10
    • 3142724732 scopus 로고    scopus 로고
    • Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
    • Bettelli E., Sullivan B., Szabo S.J., Sobel R.A., Glimcher L.H., and Kuchroo V.K. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J. Exp. Med. 200 (2004) 79-87
    • (2004) J. Exp. Med. , vol.200 , pp. 79-87
    • Bettelli, E.1    Sullivan, B.2    Szabo, S.J.3    Sobel, R.A.4    Glimcher, L.H.5    Kuchroo, V.K.6
  • 11
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., Weiner H.L., and Kuchroo V.K. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441 (2006) 235-238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 12
    • 0034960320 scopus 로고    scopus 로고
    • TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu
    • Chen W., Frank M.E., Jin W., and Wahl S.M. TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity 14 (2001) 715-725
    • (2001) Immunity , vol.14 , pp. 715-725
    • Chen, W.1    Frank, M.E.2    Jin, W.3    Wahl, S.M.4
  • 13
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., McGrady G., and Wahl S.M. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198 (2003) 1875-1886
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 14
    • 2442425262 scopus 로고    scopus 로고
    • Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants
    • Cobbold S.P., Castejon R., Adams E., Zelenika D., Graca L., Humm S., and Waldmann H. Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J. Immunol. 172 (2004) 6003-6010
    • (2004) J. Immunol. , vol.172 , pp. 6003-6010
    • Cobbold, S.P.1    Castejon, R.2    Adams, E.3    Zelenika, D.4    Graca, L.5    Humm, S.6    Waldmann, H.7
  • 15
    • 8544265317 scopus 로고    scopus 로고
    • Forkhead-box transcription factors and their role in the immune system
    • Coffer P.J., and Burgering B.M. Forkhead-box transcription factors and their role in the immune system. Nat. Rev. Immunol. 4 (2004) 889-899
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 889-899
    • Coffer, P.J.1    Burgering, B.M.2
  • 16
    • 0032211092 scopus 로고    scopus 로고
    • Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis
    • Constantinescu C.S., Wysocka M., Hilliard B., Ventura E.S., Lavi E., Trinchieri G., and Rostami A. Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis. J. Immunol. 161 (1998) 5097-5104
    • (1998) J. Immunol. , vol.161 , pp. 5097-5104
    • Constantinescu, C.S.1    Wysocka, M.2    Hilliard, B.3    Ventura, E.S.4    Lavi, E.5    Trinchieri, G.6    Rostami, A.7
  • 18
    • 10344220512 scopus 로고    scopus 로고
    • CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion
    • Curatto de Lafaille M.A., Lino A.C., Kutchukhidze N., and Lafaille J.J. CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion. J. Immunol. 173 (2004) 7258-7268
    • (2004) J. Immunol. , vol.173 , pp. 7258-7268
    • Curatto de Lafaille, M.A.1    Lino, A.C.2    Kutchukhidze, N.3    Lafaille, J.J.4
  • 19
    • 27544446622 scopus 로고    scopus 로고
    • Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
    • D'Cruz L.M., and Klein L. Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat. Immunol. 6 (2005) 1152-1159
    • (2005) Nat. Immunol. , vol.6 , pp. 1152-1159
    • D'Cruz, L.M.1    Klein, L.2
  • 20
  • 21
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
    • Fantini M.C., Becker C., Monteleone G., Pallone F., Galle P.R., and Neurath M.F. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J. Immunol. 172 (2004) 5149-5153
    • (2004) J. Immunol. , vol.172 , pp. 5149-5153
    • Fantini, M.C.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.R.5    Neurath, M.F.6
  • 22
    • 15544377954 scopus 로고    scopus 로고
    • Bordetella pertussis-infected human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization and interleukin-23 expression
    • Fedele G., Stefanelli P., Spensieri F., Fazio C., Mastrantonio P., and Ausiello C.M. Bordetella pertussis-infected human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization and interleukin-23 expression. Infect. Immun. 73 (2005) 1590-1597
    • (2005) Infect. Immun. , vol.73 , pp. 1590-1597
    • Fedele, G.1    Stefanelli, P.2    Spensieri, F.3    Fazio, C.4    Mastrantonio, P.5    Ausiello, C.M.6
  • 24
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4 (2003) 330-336
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 25
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot J.D., Rasmussen J.P., Gavin M.A., and Rudensky A.Y. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6 (2005) 1142-1151
    • (2005) Nat. Immunol. , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 26
    • 0242407713 scopus 로고    scopus 로고
    • Control of immune homeostasis by naturally arising regulatory CD4+ T cells
    • Gavin M., and Rudensky A. Control of immune homeostasis by naturally arising regulatory CD4+ T cells. Curr. Opin. Immunol. 15 (2003) 690-696
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 690-696
    • Gavin, M.1    Rudensky, A.2
  • 27
    • 1342324752 scopus 로고    scopus 로고
    • Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice
    • Ghilardi N., Kljavin N., Chen Q., Lucas S., Gurney A.L., and De Sauvage F.J. Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice. J. Immunol. 172 (2004) 2827-2833
    • (2004) J. Immunol. , vol.172 , pp. 2827-2833
    • Ghilardi, N.1    Kljavin, N.2    Chen, Q.3    Lucas, S.4    Gurney, A.L.5    De Sauvage, F.J.6
  • 28
    • 0141703239 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes
    • Green E.A., Gorelik L., McGregor C.M., Tran E.H., and Flavell R.A. CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. Proc. Natl. Acad. Sci. USA 100 (2003) 10878-10883
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10878-10883
    • Green, E.A.1    Gorelik, L.2    McGregor, C.M.3    Tran, E.H.4    Flavell, R.A.5
  • 31
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington L.E., Hatton R.D., Mangan P.R., Turner H., Murphy T.L., Murphy K.M., and Weaver C.T. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6 (2005) 1123-1132
    • (2005) Nat. Immunol. , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 32
    • 0141519112 scopus 로고    scopus 로고
    • IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells
    • Hibbert L., Pflanz S., De Waal Malefyt R., and Kastelein R.A. IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells. J. Interferon Cytokine Res. 23 (2003) 513-522
    • (2003) J. Interferon Cytokine Res. , vol.23 , pp. 513-522
    • Hibbert, L.1    Pflanz, S.2    De Waal Malefyt, R.3    Kastelein, R.A.4
  • 33
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 34
    • 0026648380 scopus 로고
    • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system
    • Hsieh C.S., Heimberger A.B., Gold J.S., O'Garra A., and Murphy K.M. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc. Natl. Acad. Sci. USA 89 (1992) 6065-6069
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6065-6069
    • Hsieh, C.S.1    Heimberger, A.B.2    Gold, J.S.3    O'Garra, A.4    Murphy, K.M.5
  • 35
    • 0027336689 scopus 로고
    • Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
    • Hsieh C.S., Macatonia S.E., Tripp C.S., Wolf S.F., O'Garra A., and Murphy K.M. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 260 (1993) 547-549
    • (1993) Science , vol.260 , pp. 547-549
    • Hsieh, C.S.1    Macatonia, S.E.2    Tripp, C.S.3    Wolf, S.F.4    O'Garra, A.5    Murphy, K.M.6
  • 36
    • 21844444831 scopus 로고    scopus 로고
    • New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
    • Hunter C.A. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol. 5 (2005) 521-531
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 521-531
    • Hunter, C.A.1
  • 37
    • 0034541221 scopus 로고    scopus 로고
    • Microbial lipopeptides induce the production of IL-17 in Th cells
    • Infante-Duarte C., Horton H.F., Byrne M.C., and Kamradt T. Microbial lipopeptides induce the production of IL-17 in Th cells. J. Immunol. 165 (2000) 6107-6115
    • (2000) J. Immunol. , vol.165 , pp. 6107-6115
    • Infante-Duarte, C.1    Horton, H.F.2    Byrne, M.C.3    Kamradt, T.4
  • 40
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R., Cox T., Yasayko S.A., and Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4 (2003) 337-342
    • (2003) Nat. Immunol. , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 41
    • 0041806547 scopus 로고    scopus 로고
    • In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro
    • Klein L., Khazaie K., and von Boehmer H. In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc. Natl. Acad. Sci. USA 100 (2003) 8886-8891
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8886-8891
    • Klein, L.1    Khazaie, K.2    von Boehmer, H.3
  • 44
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls J.K., and Lindén A. Interleukin-17 family members and inflammation. Immunity 21 (2004) 467-476
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Lindén, A.2
  • 45
    • 10344233176 scopus 로고    scopus 로고
    • Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells
    • Kubo T., Hatton R.D., Oliver J., Liu X., Elson C.O., and Weaver C.T. Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells. J. Immunol. 173 (2004) 7249-7258
    • (2004) J. Immunol. , vol.173 , pp. 7249-7258
    • Kubo, T.1    Hatton, R.D.2    Oliver, J.3    Liu, X.4    Elson, C.O.5    Weaver, C.T.6
  • 47
    • 0028966091 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12
    • Leonard J.P., Waldburger K.E., and Goldman S.J. Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12. J. Exp. Med. 181 (1995) 381-386
    • (1995) J. Exp. Med. , vol.181 , pp. 381-386
    • Leonard, J.P.1    Waldburger, K.E.2    Goldman, S.J.3
  • 48
    • 18644381773 scopus 로고    scopus 로고
    • TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: differential involvement of Stat4 and T-bet
    • Lin J.T., Martin S.L., Xia L., and Gorham J.D. TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: differential involvement of Stat4 and T-bet. J. Immunol. 174 (2005) 5950-5958
    • (2005) J. Immunol. , vol.174 , pp. 5950-5958
    • Lin, J.T.1    Martin, S.L.2    Xia, L.3    Gorham, J.D.4
  • 50
    • 1042267236 scopus 로고    scopus 로고
    • Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion
    • Lubberts E., Koenders M.I., Oppers-Walgreen B., van den Bersselaar L., Coenen-de Roo C.J., Joosten L.A., and van den Berg W.B. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum. 50 (2004) 650-659
    • (2004) Arthritis Rheum. , vol.50 , pp. 650-659
    • Lubberts, E.1    Koenders, M.I.2    Oppers-Walgreen, B.3    van den Bersselaar, L.4    Coenen-de Roo, C.J.5    Joosten, L.A.6    van den Berg, W.B.7
  • 51
    • 0344304399 scopus 로고    scopus 로고
    • IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms
    • Lucas S., Ghilardi N., Li J., and de Sauvage F.J. IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. USA 100 (2003) 15047-15052
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15047-15052
    • Lucas, S.1    Ghilardi, N.2    Li, J.3    de Sauvage, F.J.4
  • 52
    • 4944266186 scopus 로고    scopus 로고
    • A role for the immunological synapse in lineage commitment of CD4 lymphocytes
    • Maldonado R.A., Irvine D.J., Schreiber R., and Glimcher L.H. A role for the immunological synapse in lineage commitment of CD4 lymphocytes. Nature 431 (2004) 527-532
    • (2004) Nature , vol.431 , pp. 527-532
    • Maldonado, R.A.1    Irvine, D.J.2    Schreiber, R.3    Glimcher, L.H.4
  • 53
    • 0036669298 scopus 로고    scopus 로고
    • CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
    • Malek T.R., Yu A., Vincek V., Scibelli P., and Kong L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 17 (2002) 167-178
    • (2002) Immunity , vol.17 , pp. 167-178
    • Malek, T.R.1    Yu, A.2    Vincek, V.3    Scibelli, P.4    Kong, L.5
  • 55
    • 17144400393 scopus 로고    scopus 로고
    • TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Marie J.C., Letterio J.J., Gavin M., and Rudensky A.Y. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J. Exp. Med. 201 (2005) 1061-1067
    • (2005) J. Exp. Med. , vol.201 , pp. 1061-1067
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3    Rudensky, A.Y.4
  • 56
    • 0031826252 scopus 로고    scopus 로고
    • Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice
    • Matthys P., Vermeire K., Mitera T., Heremans H., Huang S., and Billiau A. Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice. Eur. J. Immunol. 28 (1998) 2143-2151
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2143-2151
    • Matthys, P.1    Vermeire, K.2    Mitera, T.3    Heremans, H.4    Huang, S.5    Billiau, A.6
  • 57
    • 0033567960 scopus 로고    scopus 로고
    • Enhanced autoimmune arthritis in IFN-gamma receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells
    • Matthys P., Vermeire K., Mitera T., Heremans H., Huang S., Schols D., De Wolf-Peeters C., and Billiau A. Enhanced autoimmune arthritis in IFN-gamma receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells. J. Immunol. 163 (1999) 3503-3510
    • (1999) J. Immunol. , vol.163 , pp. 3503-3510
    • Matthys, P.1    Vermeire, K.2    Mitera, T.3    Heremans, H.4    Huang, S.5    Schols, D.6    De Wolf-Peeters, C.7    Billiau, A.8
  • 60
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion leads to different functional properties
    • Mosmann T.R., and Coffman R.L. Th1 and Th2 cells: Different patterns of lymphokine secretion leads to different functional properties. Annu. Rev. Immunol. 7 (1989) 145-173
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 64
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy K.M., and Reiner S.L. The lineage decisions of helper T cells. Nat. Rev. Immunol. 2 (2002) 933-944
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 65
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • Nakae S., Komiyama Y., Nambu A., Sudo K., Iwase M., Homma I., Sekikawa K., Asano M., and Iwakura Y. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 17 (2002) 375-387
    • (2002) Immunity , vol.17 , pp. 375-387
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3    Sudo, K.4    Iwase, M.5    Homma, I.6    Sekikawa, K.7    Asano, M.8    Iwakura, Y.9
  • 66
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • Nakae S., Nambu A., Sudo K., and Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J. Immunol. 171 (2003) 6173-6177
    • (2003) J. Immunol. , vol.171 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 67
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K., Kitani A., and Strober W. Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. 194 (2001) 629-644
    • (2001) J. Exp. Med. , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 68
    • 1642577126 scopus 로고    scopus 로고
    • TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
    • Nakamura K., Kitani A., Fuss I., Pedersen A., Harada N., Nawata H., and Strober W. TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J. Immunol. 172 (2004) 834-842
    • (2004) J. Immunol. , vol.172 , pp. 834-842
    • Nakamura, K.1    Kitani, A.2    Fuss, I.3    Pedersen, A.4    Harada, N.5    Nawata, H.6    Strober, W.7
  • 69
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B., Lesley R., Blom B., Timans J.C., Xu Y., Hunte B., Vega F., Yu N., Wang J., Singh K., et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13 (2000) 715-725
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6    Vega, F.7    Yu, N.8    Wang, J.9    Singh, K.10
  • 71
    • 0033973582 scopus 로고    scopus 로고
    • Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
    • Ouyang W., Lohning M., Gao Z., Assenmacher M., Ranganath S., Radbruch A., and Murphy K.M. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 12 (2000) 27-37
    • (2000) Immunity , vol.12 , pp. 27-37
    • Ouyang, W.1    Lohning, M.2    Gao, Z.3    Assenmacher, M.4    Ranganath, S.5    Radbruch, A.6    Murphy, K.M.7
  • 73
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • Pasare C., and Medzhitov R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299 (2003) 1033-1036
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 74
    • 1842480959 scopus 로고    scopus 로고
    • TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
    • Peng Y., Laouar Y., Li M.O., Green E.A., and Flavell R.A. TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc. Natl. Acad. Sci. USA 101 (2004) 4572-4577
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4572-4577
    • Peng, Y.1    Laouar, Y.2    Li, M.O.3    Green, E.A.4    Flavell, R.A.5
  • 77
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi S. Regulatory T cells: Key controllers of immunologic self-tolerance. Cell 101 (2000) 455-458
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 78
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22 (2004) 531-562
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 79
    • 0027255488 scopus 로고
    • Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice
    • Scharton T.M., and Scott P. Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. J. Exp. Med. 178 (1993) 567-577
    • (1993) J. Exp. Med. , vol.178 , pp. 567-577
    • Scharton, T.M.1    Scott, P.2
  • 81
    • 0026712313 scopus 로고
    • The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
    • Seder R.A., Paul W.E., Davis M.M., and Fazekas de St Groth B. The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J. Exp. Med. 176 (1992) 1091-1098
    • (1992) J. Exp. Med. , vol.176 , pp. 1091-1098
    • Seder, R.A.1    Paul, W.E.2    Davis, M.M.3    Fazekas de St Groth, B.4
  • 82
    • 0032536447 scopus 로고    scopus 로고
    • An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
    • Segal B.M., Dwyer B.K., and Shevach E.M. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J. Exp. Med. 187 (1998) 537-546
    • (1998) J. Exp. Med. , vol.187 , pp. 537-546
    • Segal, B.M.1    Dwyer, B.K.2    Shevach, E.M.3
  • 83
    • 0037180805 scopus 로고    scopus 로고
    • Helper T cells regulate type-2 innate immunity in vivo
    • Shinkai K., Mohrs M., and Locksley R.M. Helper T cells regulate type-2 innate immunity in vivo. Nature 420 (2002) 825-829
    • (2002) Nature , vol.420 , pp. 825-829
    • Shinkai, K.1    Mohrs, M.2    Locksley, R.M.3
  • 84
    • 20444494936 scopus 로고    scopus 로고
    • Interchromosomal associations between alternatively expressed loci
    • Spilianakis C.G., Lalioti M.D., Town T., Lee G.R., and Flavell R.A. Interchromosomal associations between alternatively expressed loci. Nature 435 (2005) 637-645
    • (2005) Nature , vol.435 , pp. 637-645
    • Spilianakis, C.G.1    Lalioti, M.D.2    Town, T.3    Lee, G.R.4    Flavell, R.A.5
  • 85
    • 15244344110 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
    • Stark M.A., Huo Y., Burcin T.L., Morris M.A., Olson T.S., and Ley K. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22 (2005) 285-294
    • (2005) Immunity , vol.22 , pp. 285-294
    • Stark, M.A.1    Huo, Y.2    Burcin, T.L.3    Morris, M.A.4    Olson, T.S.5    Ley, K.6
  • 86
    • 0029931447 scopus 로고    scopus 로고
    • Immunoglobulin class switching
    • Stavnezer J. Immunoglobulin class switching. Curr. Opin. Immunol. 8 (1996) 199-205
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 199-205
    • Stavnezer, J.1
  • 87
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo S.J., Kim S.T., Costa G.L., Zhang X., Fathman C.G., and Glimcher L.H. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100 (2000) 655-669
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5    Glimcher, L.H.6
  • 88
    • 0033602101 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway
    • Ulloa L., Doody J., and Massague J. Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. Nature 397 (1999) 710-713
    • (1999) Nature , vol.397 , pp. 710-713
    • Ulloa, L.1    Doody, J.2    Massague, J.3
  • 89
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen M., Hocking R.J., Atkins C.J., Locksley R.M., and Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24 (2006) 179-189
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 91
    • 0028152937 scopus 로고
    • Transforming growth factor beta: the good, the bad, and the ugly
    • Wahl S.M. Transforming growth factor beta: the good, the bad, and the ugly. J. Exp. Med. 180 (1994) 1587-1590
    • (1994) J. Exp. Med. , vol.180 , pp. 1587-1590
    • Wahl, S.M.1
  • 92
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of denritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach A., Fournier N., Brun V., Breittmayer J.-P., Cottrez F., and Groux H. Characterization of denritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18 (2003) 605-617
    • (2003) Immunity , vol.18 , pp. 605-617
    • Wakkach, A.1    Fournier, N.2    Brun, V.3    Breittmayer, J.-P.4    Cottrez, F.5    Groux, H.6
  • 93
    • 0043244867 scopus 로고    scopus 로고
    • Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo
    • Walker L.S., Chodos A., Eggena M., Dooms H., and Abbas A.K. Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J. Exp. Med. 198 (2003) 249-258
    • (2003) J. Exp. Med. , vol.198 , pp. 249-258
    • Walker, L.S.1    Chodos, A.2    Eggena, M.3    Dooms, H.4    Abbas, A.K.5
  • 95
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • Wan Y.Y., and Flavell R.A. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc. Natl. Acad. Sci. USA 102 (2005) 5126-5131
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 96
    • 8444242090 scopus 로고    scopus 로고
    • Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet
    • Way S.S., and Wilson C.B. Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet. J. Immunol. 173 (2004) 5918-5922
    • (2004) J. Immunol. , vol.173 , pp. 5918-5922
    • Way, S.S.1    Wilson, C.B.2
  • 97
    • 0030587910 scopus 로고    scopus 로고
    • IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • Willenborg D.O., Fordham S., Bernard C.C., Cowden W.B., and Ramshaw I.A. IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 157 (1996) 3223-3227
    • (1996) J. Immunol. , vol.157 , pp. 3223-3227
    • Willenborg, D.O.1    Fordham, S.2    Bernard, C.C.3    Cowden, W.B.4    Ramshaw, I.A.5
  • 98
    • 0034965185 scopus 로고    scopus 로고
    • Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms
    • Wolf M., Schimpl A., and Hunig T. Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms. Eur. J. Immunol. 31 (2001) 1637-1645
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1637-1645
    • Wolf, M.1    Schimpl, A.2    Hunig, T.3
  • 99
    • 0042512461 scopus 로고    scopus 로고
    • Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
    • Yamazaki S., Iyoda T., Tarbell K., Olson K., Velinzon K., Inaba K., and Steinman R.M. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198 (2003) 235-247
    • (2003) J. Exp. Med. , vol.198 , pp. 235-247
    • Yamazaki, S.1    Iyoda, T.2    Tarbell, K.3    Olson, K.4    Velinzon, K.5    Inaba, K.6    Steinman, R.M.7
  • 100
    • 0033033469 scopus 로고    scopus 로고
    • Induction of interferon-gamma production in Th1 CD4+ T cells: evidence for two distinct pathways for promoter activation
    • Yang J., Murphy T.L., Ouyang W., and Murphy K.M. Induction of interferon-gamma production in Th1 CD4+ T cells: evidence for two distinct pathways for promoter activation. Eur. J. Immunol. 29 (1999) 548-555
    • (1999) Eur. J. Immunol. , vol.29 , pp. 548-555
    • Yang, J.1    Murphy, T.L.2    Ouyang, W.3    Murphy, K.M.4
  • 101
    • 0037442020 scopus 로고    scopus 로고
    • Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system
    • Zhang G.X., Gran B., Yu S., Li J., Siglienti I., Chen X., Kamoun M., and Rostami A. Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J. Immunol. 170 (2003) 2153-2160
    • (2003) J. Immunol. , vol.170 , pp. 2153-2160
    • Zhang, G.X.1    Gran, B.2    Yu, S.3    Li, J.4    Siglienti, I.5    Chen, X.6    Kamoun, M.7    Rostami, A.8
  • 102
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng W., and Flavell R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89 (1997) 587-596
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2


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