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Volumn 171, Issue 5, 2003, Pages 2270-2278

Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD4 ANTIGEN; INSULIN ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OVALBUMIN; PARVOVIRUS VECTOR; RNA; VIRUS VECTOR;

EID: 0042931258     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.5.2270     Document Type: Article
Times cited : (118)

References (31)
  • 1
    • 0035928391 scopus 로고    scopus 로고
    • Type 1 diabetes: New perspectives on disease pathogenesis and treatment
    • Atkinson, M., and G. Eisenbarth. 2001. Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 358:221.
    • (2001) Lancet , vol.358 , pp. 221
    • Atkinson, M.1    Eisenbarth, G.2
  • 2
    • 0032701409 scopus 로고    scopus 로고
    • The role of CD4 vs. CD8 T cells in IDDM
    • Wong, F. S., and C. A. J. Janeway. 1999. The role of CD4 vs. CD8 T cells in IDDM. J. Autoimmun. 13:290.
    • (1999) J. Autoimmun. , vol.13 , pp. 290
    • Wong, F.S.1    Janeway, C.A.J.2
  • 3
    • 0032957714 scopus 로고    scopus 로고
    • Redirecting Th1 and Th2 responses in autoimmune disease
    • Pearson, C. I., and H. O. McDevitt. 1999. Redirecting Th1 and Th2 responses in autoimmune disease. Curr. Top. Microbiol. Immunol. 238:79.
    • (1999) Curr. Top. Microbiol. Immunol. , vol.238 , pp. 79
    • Pearson, C.I.1    McDevitt, H.O.2
  • 4
    • 0035692747 scopus 로고    scopus 로고
    • Approaches to type 1 diabetes prevention by intervention in cytokine immunoregulatory circuits
    • Suarez-Pinzon, W. L., and A. Rabinovitch. 2001. Approaches to type 1 diabetes prevention by intervention in cytokine immunoregulatory circuits, Int. J. Exp. Diabetes Res. 2:3.
    • (2001) Int. J. Exp. Diabetes Res. , vol.2 , pp. 3
    • Suarez-Pinzon, W.L.1    Rabinovitch, A.2
  • 5
    • 0033001488 scopus 로고    scopus 로고
    • The NOD mouse model of type 1 diabetes: As good as it gets?
    • Atkinson, M. A., and E. H. Leiter. 1999. The NOD mouse model of type 1 diabetes: as good as it gets? Nat. Med. 5:601.
    • (1999) Nat. Med. , vol.5 , pp. 601
    • Atkinson, M.A.1    Leiter, E.H.2
  • 7
    • 0037310860 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses
    • Ding, Y., D. Chen, A. Tarcsafalvi, R. Su, L. Qin, and J. S. Bromberg. 2003. Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses. J. Immunol. 170:1383.
    • (2003) J. Immunol. , vol.170 , pp. 1383
    • Ding, Y.1    Chen, D.2    Tarcsafalvi, A.3    Su, R.4    Qin, L.5    Bromberg, J.S.6
  • 10
    • 0035862333 scopus 로고    scopus 로고
    • Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
    • Dhodapkar, M. V., R. M. Steinman, J. Krasovsky, C. Munz, and N. Bhardway. 2001. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J. Exp. Med. 193:233.
    • (2001) J. Exp. Med. , vol.193 , pp. 233
    • Dhodapkar, M.V.1    Steinman, R.M.2    Krasovsky, J.3    Munz, C.4    Bhardway, N.5
  • 14
    • 0034840167 scopus 로고    scopus 로고
    • An overview of regulatory T cells
    • Groux, H. 2001. An overview of regulatory T cells. Microbes Infect. 3:883.
    • (2001) Microbes Infect. , vol.3 , pp. 883
    • Groux, H.1
  • 15
    • 0029942029 scopus 로고    scopus 로고
    • The paradoxical effects of interleukin 10 in the immunoregulation of autoimmune diabetes
    • Balasa, B., and N. Sarvetnick. 1996. The paradoxical effects of interleukin 10 in the immunoregulation of autoimmune diabetes. J. Autoimmun. 9:283.
    • (1996) J. Autoimmun. , vol.9 , pp. 283
    • Balasa, B.1    Sarvetnick, N.2
  • 16
    • 0034659113 scopus 로고    scopus 로고
    • IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse
    • Balasa, B., K. Van Gunst, N. Jung, J. D. Katz, and N. Sarvetnick. 2000. IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse. Cell. Immunol. 202:97.
    • (2000) Cell. Immunol. , vol.202 , pp. 97
    • Balasa, B.1    Van Gunst, K.2    Jung, N.3    Katz, J.D.4    Sarvetnick, N.5
  • 17
    • 0028222756 scopus 로고
    • Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse
    • Pennline, K. J., E. Roque-Gaffney, and M. Monahan. 1994. Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse. Clin. Immunol. Immunopathol. 71:169.
    • (1994) Clin. Immunol. Immunopathol. , vol.71 , pp. 169
    • Pennline, K.J.1    Roque-Gaffney, E.2    Monahan, M.3
  • 18
    • 0032504602 scopus 로고    scopus 로고
    • Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice
    • Nitta, Y., F. Tashiro, M. Tokui, A. Shimada, I. Takei, K. Tabayashi, and J. Miyazaki. 1998. Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice. Hum. Gene Ther. 9:1701.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1701
    • Nitta, Y.1    Tashiro, F.2    Tokui, M.3    Shimada, A.4    Takei, I.5    Tabayashi, K.6    Miyazaki, J.7
  • 20
    • 0028346888 scopus 로고
    • Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in nonobese diabetic mice
    • Wogensen, L., M. S. Lee, and N. Sarvetnick. 1994. Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in nonobese diabetic mice. J. Exp. Med. 179:1379.
    • (1994) J. Exp. Med. , vol.179 , pp. 1379
    • Wogensen, L.1    Lee, M.S.2    Sarvetnick, N.3
  • 21
    • 0030773969 scopus 로고    scopus 로고
    • Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice
    • Smith, D. K., G. S. Korbutt, W. L. Suarez-Pinzon, D. Kao, R. V. Rajotte, and J. F. Elliott. 1997. Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice. Transplantation 64:1040.
    • (1997) Transplantation , vol.64 , pp. 1040
    • Smith, D.K.1    Korbutt, G.S.2    Suarez-Pinzon, W.L.3    Kao, D.4    Rajotte, R.V.5    Elliott, J.F.6
  • 22
    • 0031680620 scopus 로고    scopus 로고
    • Decreased in vitro IL-4 and IL-10 production by peripheral blood in first degree relatives at high risk of diabetes type-I
    • Szelachowska, M., A. Kretowski, and I. Kinalska. 1998. Decreased in vitro IL-4 and IL-10 production by peripheral blood in first degree relatives at high risk of diabetes type-I. Horm. Metab. Res. 30:526.
    • (1998) Horm. Metab. Res. , vol.30 , pp. 526
    • Szelachowska, M.1    Kretowski, A.2    Kinalska, I.3
  • 23
    • 0033939014 scopus 로고    scopus 로고
    • Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: Elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice
    • Alleva, D. G., R. P. Pavlovich, C. Grant, S. B. Kaser, and D. I. Beller. 2000. Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice. Diabetes 49:1106.
    • (2000) Diabetes , vol.49 , pp. 1106
    • Alleva, D.G.1    Pavlovich, R.P.2    Grant, C.3    Kaser, S.B.4    Beller, D.I.5
  • 25
    • 0032190675 scopus 로고    scopus 로고
    • Adeno-associated virus expression systems for gene transfer
    • Rabinowitz, J. E., and J. Samulski. 1998. Adeno-associated virus expression systems for gene transfer. Curr. Opin. Biotechnol. 9:470.
    • (1998) Curr. Opin. Biotechnol. , vol.9 , pp. 470
    • Rabinowitz, J.E.1    Samulski, J.2
  • 28
    • 0036721772 scopus 로고    scopus 로고
    • - splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7
    • - splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7. J. Immunol. 169:2461.
    • (2002) J. Immunol. , vol.169 , pp. 2461
    • Szanya, V.1    Ermann, J.2    Taylor, C.3    Holness, C.4    Fathman, C.G.5
  • 31
    • 85039639373 scopus 로고    scopus 로고
    • + anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity
    • + anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity. Blood 93:1634.
    • (2002) Blood , vol.93 , pp. 1634
    • Steinbrink, K.1    Graulich, E.2    Kubsch, S.3    Knop, J.4    Enk, A.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.