Mixed allogeneic chimerism achieved by lethal and nonlethal conditioning approaches induces donor-specific tolerance to simultaneous islet allografts

Transplantation

Volumn 60, Issue 6, 1995, Pages 523-529

  Li, Hua ^a   Colson, Yolonda L ^a   Ildstad, Suzanne T ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CELL TRANSPLANTATION; CHIMERA; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOLOGICAL TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; MIXED LYMPHOCYTE CULTURE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMAL; BONE MARROW TRANSPLANTATION; GRAFT SURVIVAL; IMMUNE TOLERANCE; IMMUNOSUPPRESSION; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RADIATION CHIMERA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029092748     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199509270-00001     Document Type: Article

References (30)

1. Castano L, Eisenbarth GS. Type-1 diabetes: a chronic autoim mune disease of human, mouse, and rat. Annu Rev Immunol 1990; 8: 647.
2. Winter RJ. New developments in type I diabetes. Curr Probl Pediatr 1991; 21: 85.
3. Dubernard JM, Sutherland DER. Introduction and history of pancreatic transplantation. In: Dubernard JM, Sutherland DER, eds. International handbook of pancreas transplantation. Dordrecht: Kluwer Academic, 1989: 1.
4. Mintz DH, Alejandro R. Islet cell transplantation. In: Ricordi C, ed. Pancreatic islet cell transplantation, 1892-1992: One century of transplantation for diabetes. Austin, TX: RG Landes, 1992: 1.
5. Hering BJ, Browafzki CC, Schultz AO, Watz B, Bretzel RG, Federlin K. Results on all adult islet allografts known to be performed world-wide with main emphasis on the period from January 1, 1990 to June 30, 1992. Islet Transplant Registry Newsletter No. 3, November 1992.
6. Faustman D, Hauptfeld V, Pavie JM, Lacy PE. Prolongation of murine islet allograft survival by pretreatment of islets with antibody directed to la determinants. Proc Natl Acad Sci USA 1981; 78: 5156.
7. Faustman D, Lacy PE, David JM, Hauptfeld V. Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody. Proc Natl Acad Sci USA 1984; 81: 3864.
8. Lacy PE, Davie JM, Finke EH. Prolongation of islet allograft survival following in vitro culture (24°C) and a single injection of ALS. Science 1979; 204: 312.
9. Lua H, Reemtsma K, Hardy MA: Pancreatic islet allograft pro longation by donor-specific blood transfusion treated with ultraviolet irradiation. Science 1983; 222: 754.
10. Lim F, Sun AM. Microencapsulated islet as bioartifìcial endo crine pancreas. Science 1980; 210: 908.
11. Gotoh M, Maki T, Satomi S, Porter J, Monaco AP. Immunological characteristics of purified pancreatic islet grafts. Transplantation 1986; 42: 387.
12. Ildstad ST, Sachs DH. Reconstitution with syngeneic plus allo geneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 1984; 307: 170.
13. Ildstad ST, Wren SM, Bluestone JA, Barbieri SA, Sachs DH. Characterization of mixed allogeneic chimeras: immunocom-petence, in vitro reactivity and genetic specificity of tolerance. J Exp Med 1985; 162: 23.
14. Ildstad ST, Wren SM, Bluestone JA, Barbieri SA, Stephany D, Sachs DH. Effect of selective T cell depletion of host and/or donor bone marrow on lymphopoietic repopulation, tolerance, and graft versus host disease in mixed allogeneic chimeras (B10+B10. D2→B10). J Immunol 1986; 136: 28.
15. Ildstad ST, Wren SM, Oh E, Hronakes ML. Mixed allogeneic reconstitution (A+B→A) to induce donor-specific transplantation tolerance: permanent acceptance of simultaneous skin grafts. Transplantation. 1991; 51: 1262.
16. Ildstad ST, Boggs SS, Vecchini F, Wren SM, Hronakes ML, Johnson PG, Van den Brink MRM. Mixed xenogeneic chimeras (rat+mouse→rat): evidence for rat stem cell engraftment, strain-specific transplantation tolerance, and skin-specific antigens. Transplantation 1992; 53: 815.
17. Zeng YJ, Ricordi C, Tzakis A, Rilo HLR, Carroll PB, Starzl TE, Ildstad ST. Long-term survival of donor-specific pancreatic islet xenografts in fully xenogeneic chimeras (WF rat≥BlO mouse). Transplantation 1992; 53: 277.
18. Li H, Ricordi C, Demetris AJ, Kaufman CL, Korbanic C, Hronakes ML, Ildstad ST. Mixed xenogeneic chimerism (mouse+rat→mouse) to induce donor-specific tolerance to sequential or simultaneous islet xenografts. Transplantation 1994; 57: 592.
19. Mayumi H, Good RA. Long-lasting skin allograft tolerance in adult mice induced across fully allogeneic (multimajor H-2 plus multiminor histocompatibility) antigen barriers by a tol-erance-inducing method using cyclophosphamide. J Exp Med 1989; 169: 213.
20. Slavin S, Reitz B, Bieber CP, Kaplan HE, Strober S. Transplantation tolerance in adult rats using total lymphoid irradiation: permanent survival of skin, heart, and marrow allografts. J Exp Med 1978; 147: 700.
21. McCarthy SA, Griffith IF, Gambel P, Francescutti LH, Wegman TG. Characterization of host lymphoid cells in antibody-facilitated bone marrow chimeras. Transplantation 1985; 40: 12.
22. Monaco AP, Wood ML, Russell PS. Studies on heterologus anti lymphocyte serum in mice: III. Immunologic tolerance and chimerism produced across the H-2 locus with adult thymectomy and antilymphocyte serum. Ann NY Acad Sci 1966; 129: 190.
23. Cobbold SP, Martin G, Qin S, Waldmann H. Monoclonal anti bodies to promote marrow engraftment and tissue graft tolerance. Nature 1986; 323: 164.
24. Cobbold SP, Qin S, Leong LYW, Martin G, Waldmann H. Repro gramming of the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies. Immunol Rev 1992; 129: 165.
25. Sharabi Y, Sachs DH. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med 1989; 169: 493.
26. Hoffman RA, Langrehr JM, Billiar TR, Curran RD, Simmons RL. Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine. J Immunol 1990; 145: 2220.
27. Ricordi C, Lacy PE, Finke EH, Olack BJ, Scharp DW. Automated method for isolation of human pancreatic islets. Diabetes 1988; 37: 413.
28. Ricordi C, Gray DWR, Hering BJ, et al. Islet isolation assess ment in man and large animals. Acta Diabetol Latina 1990; 27: 185.
29. Wilson JD, Prowse SJ, Haynes SP. Pancreatic islet allograft function in nonimmunosuppressed conscious mice. Metabolism 1985; 34: 92.
30. Gjertson DW. Survival trends in long-term first cadaveric donor kidney transplants. In: P. Terasaki, ed. Clinical transplants 1991. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1992: 225.