메뉴 건너뛰기




Volumn 102, Issue 3, 1998, Pages 516-526

IL-1 produced and released endogenously within human islets inhibits β cell function

Author keywords

Human islets; Inducible nitric oxide synthase; Insulin dependent diabetes mellitus; Interleukin 1; Macrophages

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR;

EID: 0032146564     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI844     Document Type: Article
Times cited : (220)

References (34)
  • 1
    • 0028206337 scopus 로고
    • The intraislet macrophage and type I diabetes
    • Lacy, P.E. 1994. The intraislet macrophage and type I diabetes. Mount Sinai J. Med. 61:170-174.
    • (1994) Mount Sinai J. Med. , vol.61 , pp. 170-174
    • Lacy, P.E.1
  • 2
    • 0023891530 scopus 로고
    • Essential fatty acid depletion of renal allografts and prevention of rejection
    • Schreiner, G.F., W. Fly, E. Brunt, K. Korber, and J.B. Lefkowith. 1988. Essential fatty acid depletion of renal allografts and prevention of rejection. Science. 240:1032-1033.
    • (1988) Science , vol.240 , pp. 1032-1033
    • Schreiner, G.F.1    Fly, W.2    Brunt, E.3    Korber, K.4    Lefkowith, J.B.5
  • 3
    • 2842526639 scopus 로고
    • Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice
    • Wright, J.R., J.B. Lefkowith, G. Schreiner, and P.E. Lacy. 1988. Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice. Proc. Natl. Acad. Sci. USA. 85:6137-6141.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6137-6141
    • Wright, J.R.1    Lefkowith, J.B.2    Schreiner, G.3    Lacy, P.E.4
  • 4
    • 0025361556 scopus 로고
    • Prevention of diabetes in the BB rat by essential fatty acid-deficiency. Relationship between physiological and biochemical changes
    • Lefkowith, J.B., G. Schreiner, J. Cormier, E.S. Handler, H.K. Driscoll, D. Greiner, J.P. Mordes, and A.A. Rossini. 1990. Prevention of diabetes in the BB rat by essential fatty acid-deficiency. Relationship between physiological and biochemical changes. J. Exp. Med. 171:729-743.
    • (1990) J. Exp. Med. , vol.171 , pp. 729-743
    • Lefkowith, J.B.1    Schreiner, G.2    Cormier, J.3    Handler, E.S.4    Driscoll, H.K.5    Greiner, D.6    Mordes, J.P.7    Rossini, A.A.8
  • 5
    • 0021960651 scopus 로고
    • Administration of silica prevents diabetes in BB rats
    • Oschilewski, U., U. Kiesel, and H. Kolb. 1985. Administration of silica prevents diabetes in BB rats. Diabetes. 34:197-199.
    • (1985) Diabetes , vol.34 , pp. 197-199
    • Oschilewski, U.1    Kiesel, U.2    Kolb, H.3
  • 6
    • 0025802116 scopus 로고
    • Activation of intraislet lymphoid cells causes destruction of islet cells
    • Lacy, P.E., and E.H. Finke. 1991. Activation of intraislet lymphoid cells causes destruction of islet cells. Am. J. Pathol. 138:1183-1190.
    • (1991) Am. J. Pathol. , vol.138 , pp. 1183-1190
    • Lacy, P.E.1    Finke, E.H.2
  • 7
    • 0028900805 scopus 로고
    • Intraislet release of IL-1 inhibits β cell function by inducing β cell expression of iNOS
    • Corbett, J.A., and M.L. McDaniel. 1995. Intraislet release of IL-1 inhibits β cell function by inducing β cell expression of iNOS. J. Exp. Med. 181:559-568.
    • (1995) J. Exp. Med. , vol.181 , pp. 559-568
    • Corbett, J.A.1    McDaniel, M.L.2
  • 8
    • 0029745336 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors prevent cytokine-induced expression of iNOS and COX-2 by human islets of Langerhans
    • Corbett, J.A., G. Kwon, M. Marino, C.P. Rodi, P.M. Sullivan, and M.L. McDaniel. 1996. Tyrosine kinase inhibitors prevent cytokine-induced expression of iNOS and COX-2 by human islets of Langerhans. Am. J. Physiol. 39: C1581-C1587.
    • (1996) Am. J. Physiol. , vol.39
    • Corbett, J.A.1    Kwon, G.2    Marino, M.3    Rodi, C.P.4    Sullivan, P.M.5    McDaniel, M.L.6
  • 10
    • 0017727975 scopus 로고
    • Preparation of single cells from pancreatic islets of adult rat by the use of dispase
    • Ono, J., R. Takaki, and M. Fukuma. 1977. Preparation of single cells from pancreatic islets of adult rat by the use of dispase. Endocrinol. Jpn. 24: 265-270.
    • (1977) Endocrinol. Jpn. , vol.24 , pp. 265-270
    • Ono, J.1    Takaki, R.2    Fukuma, M.3
  • 12
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA correlates with recovery
    • Kennedy, M.K., D.S. Torrance, K.S. Picha, and K.M. Mohler. 1992. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA correlates with recovery. J. Immunol. 149:2496-2505.
    • (1992) J. Immunol. , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 13
    • 0028989087 scopus 로고
    • IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice
    • Rabinovitch, A., W.L. Saurez-Pinzon, O. Sorensen, R.C. Bleackley, and R.F. Power. 1995. IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice. J. Immunol. 154:4874-1882.
    • (1995) J. Immunol. , vol.154 , pp. 4874-11882
    • Rabinovitch, A.1    Saurez-Pinzon, W.L.2    Sorensen, O.3    Bleackley, R.C.4    Power, R.F.5
  • 17
    • 0029989197 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice. Identification of iNOS expression cells and relationship to cytokines expressed in the islets
    • Rabinovitch, A., W.L. Saurez-Pinzon, O. Sorensen, and R.C. Bleackley. 1996. Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice. Identification of iNOS expression cells and relationship to cytokines expressed in the islets. Endocrinology. 137:2093-2099.
    • (1996) Endocrinology , vol.137 , pp. 2093-2099
    • Rabinovitch, A.1    Saurez-Pinzon, W.L.2    Sorensen, O.3    Bleackley, R.C.4
  • 18
    • 0030995686 scopus 로고    scopus 로고
    • Treatment with neutralizing antibodies specific for IL-1β prevents cyclophosphamide-induced diabetes in nonobese diabetic mice
    • Cailleau, C., A. Diu-Hercend, E. Ruuth, R. Westwood, and C. Carnaud. 1997. Treatment with neutralizing antibodies specific for IL-1β prevents cyclophosphamide-induced diabetes in nonobese diabetic mice. Diabetes. 46:937-940.
    • (1997) Diabetes , vol.46 , pp. 937-940
    • Cailleau, C.1    Diu-Hercend, A.2    Ruuth, E.3    Westwood, R.4    Carnaud, C.5
  • 19
    • 0029811755 scopus 로고    scopus 로고
    • Nitric oxide regulates interleukin-1 bioactivity released from murine macrophages
    • Hill, J.R., J.A. Corbett, G. Kwon, C.A. Marshall, and M.L. McDaniel. 1996. Nitric oxide regulates interleukin-1 bioactivity released from murine macrophages. J. Biol. Chem. 271:22672-22678.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22672-22678
    • Hill, J.R.1    Corbett, J.A.2    Kwon, G.3    Marshall, C.A.4    McDaniel, M.L.5
  • 21
    • 0028025024 scopus 로고
    • Interleukin-1 is released by murine macrophages during apoptosis induced by Shigella flexneri
    • Zychlinsky, A., C. Fitting, J.M. Cavaillon, and P.J. Sansonetti. 1994. Interleukin-1 is released by murine macrophages during apoptosis induced by Shigella flexneri. J. Clin. Invest. 94:1328-1332.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1328-1332
    • Zychlinsky, A.1    Fitting, C.2    Cavaillon, J.M.3    Sansonetti, P.J.4
  • 22
    • 2642657411 scopus 로고    scopus 로고
    • IFN-γ increases the sensitivity of islets of Langerhans for iNOS expression induced by IL-1
    • Heitmeier, M.R., A.L. Scarim, and J.A. Corbett. 1997. IFN-γ increases the sensitivity of islets of Langerhans for iNOS expression induced by IL-1. J. Biol. Chem. 272:13653-13661.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13653-13661
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 24
    • 0029120194 scopus 로고
    • Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo
    • Guo, F.H., H.R. DeRaeve, T.W. Rice, D.J. Stuehr, F.B. Thunnissen, and S.C. Erzurum. 1995. Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo. Proc. Natl. Acad. Sci. USA. 92:7809-7813.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7809-7813
    • Guo, F.H.1    Deraeve, H.R.2    Rice, T.W.3    Stuehr, D.J.4    Thunnissen, F.B.5    Erzurum, S.C.6
  • 25
    • 0030978237 scopus 로고    scopus 로고
    • Identification of inducible nitric oxide synthase in human macrophages surrounding loosened hip prostheses
    • Watkins, S.C., W. Macaulay, D. Turner, R. Kang, H.E. Rubash, and C.H. Evans. 1997. Identification of inducible nitric oxide synthase in human macrophages surrounding loosened hip prostheses. Am. J. Pathol. 150:1199-1206.
    • (1997) Am. J. Pathol. , vol.150 , pp. 1199-1206
    • Watkins, S.C.1    Macaulay, W.2    Turner, D.3    Kang, R.4    Rubash, H.E.5    Evans, C.H.6
  • 26
    • 0029592781 scopus 로고
    • On the expression of nitric oxide synthase by human macrophages. Why no NO?
    • Albina, J.E. 1995. On the expression of nitric oxide synthase by human macrophages. Why no NO? J. Leukocyte Biol. 58:643-649.
    • (1995) J. Leukocyte Biol. , vol.58 , pp. 643-649
    • Albina, J.E.1
  • 27
    • 0030890588 scopus 로고    scopus 로고
    • Cell death mediators in autoimmune diabetes. No shortage of suspects
    • Benoist, C. and D. Mathis. 1997. Cell death mediators in autoimmune diabetes. No shortage of suspects. Cell. 89:1-3.
    • (1997) Cell. , vol.89 , pp. 1-3
    • Benoist, C.1    Mathis, D.2
  • 28
    • 0019870959 scopus 로고
    • Diabetes in identical twins: A study of 200 pairs
    • Barnett, A.H., C. Eff, R.D. Leslie, and D.A. Pyke. 1981. Diabetes in identical twins: a study of 200 pairs. Diabetologia. 20:87-93.
    • (1981) Diabetologia , vol.20 , pp. 87-93
    • Barnett, A.H.1    Eff, C.2    Leslie, R.D.3    Pyke, D.A.4
  • 29
    • 0028026652 scopus 로고
    • Insulin-dependent diabetes mellitus as an autoimmune disease
    • Bach, J.-F. 1994. Insulin-dependent diabetes mellitus as an autoimmune disease. Endocrinol. Rev. 15:516-541.
    • (1994) Endocrinol. Rev. , vol.15 , pp. 516-541
    • Bach, J.-F.1
  • 30
    • 0026001434 scopus 로고
    • Role of viruses in the pathogenesis of IDDM
    • Yoon, J.W. 1991. Role of viruses in the pathogenesis of IDDM. Ann. Med. 23:437-445.
    • (1991) Ann. Med. , vol.23 , pp. 437-445
    • Yoon, J.W.1
  • 31
    • 0019400456 scopus 로고
    • Autoimmunity in insulin-dependent diabetes mellitus
    • Nerup, J., and A. Lernmark. 1981. Autoimmunity in insulin-dependent diabetes mellitus. Am. J. Med. 70:135-141.
    • (1981) Am. J. Med. , vol.70 , pp. 135-141
    • Nerup, J.1    Lernmark, A.2
  • 32
    • 0027131531 scopus 로고
    • Role of macrophage cytokines in influenza a virus infections
    • Peschke, T., A. Bender, M. Nain, and D. Gemsa. 1993. Role of macrophage cytokines in influenza A virus infections. Immunobiology. 189:340-355.
    • (1993) Immunobiology , vol.189 , pp. 340-355
    • Peschke, T.1    Bender, A.2    Nain, M.3    Gemsa, D.4
  • 33
    • 0026520210 scopus 로고
    • Coxsackie virus B3-induced production of tumor necrosis factor-alpha. IL-1 beta and IL-6 in human monocytes
    • Henke, A., C. Mohr, C. Graebner, A. Stelzner, M. Nain, and D. Gernsa. 1992. Coxsackie virus B3-induced production of tumor necrosis factor-alpha. IL-1 beta and IL-6 in human monocytes. J. Immunol. 148:2270-2277.
    • (1992) J. Immunol. , vol.148 , pp. 2270-2277
    • Henke, A.1    Mohr, C.2    Graebner, C.3    Stelzner, A.4    Nain, M.5    Gernsa, D.6
  • 34
    • 0032511096 scopus 로고    scopus 로고
    • Double-stranded RNA-induced iNOS expression and IL-1 release by murine macrophages requires NF-kB activation
    • Heitmeier, M.A., A.L. Scarim, and J.A. Corbett. 1998. Double-stranded RNA-induced iNOS expression and IL-1 release by murine macrophages requires NF-kB activation. J. Biol. Chem. 273:15301-15307.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15301-15307
    • Heitmeier, M.A.1    Scarim, A.L.2    Corbett, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.