Intramuscular injection of interleukin-10 plasmid DNA prevented autoimmune diabetes in mice

Acta Pharmacologica Sinica

Volumn 24, Issue 8, 2003, Pages 751-756

  Zhang, Zhen Lin ^b,c   Shen, Shui Xian ^b   Lin, Bo ^a   Yu, Lu Yang ^a   Zhu, Li Hua ^a   Wang, Wei Ping ^b   Luo, Fei Hong ^b   Guo, Li He ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b FUDAN UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Gene therapy; Insulin dependent diabetes mellitus; Interferon type II; Interleukin 10; Intramuscular injections; Mice; Spleen; Tumor necrosis factor

Indexed keywords

DNA; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; MESSENGER RNA; PLASMID DNA; STREPTOZOCIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DIABETES MELLITUS; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL DIABETES MELLITUS; GENE THERAPY; GENETICS; GLUCOSE BLOOD LEVEL; IATROGENIC DISEASE; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; INTRAMUSCULAR DRUG ADMINISTRATION; LYMPHOCYTE COUNT; MALE; METABOLISM; MOUSE; MOUSE STRAIN; NONHUMAN; PANCREAS; PATHOLOGY; PLASMID; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DNA; GENE THERAPY; INJECTIONS, INTRAMUSCULAR; INTERLEUKIN-1; INTERLEUKIN-10; MICE; MICE, INBRED C57BL; PANCREAS; PLASMIDS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0042404129     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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