메뉴 건너뛰기




Volumn 15, Issue 10, 2005, Pages 749-769

The role of apoptosis in the development and function of T lymphocytes

Author keywords

Apoptosis; Effector; Memory T lymphocytes; Thymocyte

Indexed keywords

PROTEIN BCL 2; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 27844539406     PISSN: 10010602     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cr.7290345     Document Type: Review
Times cited : (129)

References (247)
  • 1
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004; 116:205-19.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 2
    • 0021934042 scopus 로고
    • Cloning the chromosomal breakpoint of t(14;18) human lymphomas: Clustering around JH on chromosome 14 and near a transcriptional unit on 18
    • Bakhshi A, Jensen JP, Goldman P, et al. Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell 1985; 41:899-906.
    • (1985) Cell , vol.41 , pp. 899-906
    • Bakhshi, A.1    Jensen, J.P.2    Goldman, P.3
  • 3
    • 0033258120 scopus 로고    scopus 로고
    • Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis?
    • Vander Heiden MG, Thompson CB. Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis? Nat Cell Biol 1999; 1:E209-16.
    • (1999) Nat Cell Biol , vol.1
    • Vander Heiden, M.G.1    Thompson, C.B.2
  • 4
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999; 13:1899-911.
    • (1999) Genes Dev , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 5
    • 0031918223 scopus 로고    scopus 로고
    • BCL-2 family: Regulators of cell death
    • Chao DT, Korsmeyer SJ. BCL-2 family: regulators of cell death. Annu Rev Immunol 1998; 16:395-419.
    • (1998) Annu Rev Immunol , vol.16 , pp. 395-419
    • Chao, D.T.1    Korsmeyer, S.J.2
  • 6
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 1993; 75:229-40.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 7
    • 0028175759 scopus 로고
    • Targeted disruption of Bcl-2 alpha beta in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
    • U S A
    • Nakayama K, Negishi I, Kuida K, Sawa H, Loh DY. Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc Natl Acad Sci U S A 1994; 91:3700-4.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 3700-3704
    • Nakayama, K.1    Negishi, I.2    Kuida, K.3    Sawa, H.4    Loh, D.Y.5
  • 8
    • 0030893390 scopus 로고    scopus 로고
    • Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell
    • Matsuzaki Y, Nakayama K, Tomita T, et al. Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell. Blood 1997; 89:853-62.
    • (1997) Blood , vol.89 , pp. 853-862
    • Matsuzaki, Y.1    Nakayama, K.2    Tomita, T.3
  • 9
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi K, Kondo M, von Freeden-Jeffry U, Murray R, Weissman IL. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 1997; 89:1033-41.
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    Von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 10
    • 0031587875 scopus 로고    scopus 로고
    • Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice
    • Maraskovsky E, O'Reilly LA, Teepe M, et al. Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice. Cell 1997; 89:1011-9.
    • (1997) Cell , vol.89 , pp. 1011-1019
    • Maraskovsky, E.1    O'Reilly, L.A.2    Teepe, M.3
  • 11
    • 0027282044 scopus 로고
    • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993; 74:597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3
  • 12
    • 0028170778 scopus 로고
    • bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria
    • Gonzalez-Garcia M, Perez-Ballestero R, Ding L, et al. bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development 1994; 120:3033-42.
    • (1994) Development , vol.120 , pp. 3033-3042
    • Gonzalez-Garcia, M.1    Perez-Ballestero, R.2    Ding, L.3
  • 13
    • 0028152659 scopus 로고
    • Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes
    • Fang W, Rivard JJ, Mueller DL, Behrens TW. Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes. J Immunol 1994; 153:4388-98.
    • (1994) J Immunol , vol.153 , pp. 4388-4398
    • Fang, W.1    Rivard, J.J.2    Mueller, D.L.3    Behrens, T.W.4
  • 14
    • 17544368001 scopus 로고    scopus 로고
    • An additional form of rat Bcl-x, Bcl-xbeta, generated by an unspliced RNA, promotes apoptosis in promyeloid cells
    • Shiraiwa N, Inohara N, Okada S, et al. An additional form of rat Bcl-x, Bcl-xbeta, generated by an unspliced RNA, promotes apoptosis in promyeloid cells. J Biol Chem 1996; 271:13258-65.
    • (1996) J Biol Chem , vol.271 , pp. 13258-13265
    • Shiraiwa, N.1    Inohara, N.2    Okada, S.3
  • 15
    • 0031447458 scopus 로고    scopus 로고
    • A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells
    • Yang XF, Weber GF, Cantor H. A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells. Immunity 1997; 7:629-39.
    • (1997) Immunity , vol.7 , pp. 629-639
    • Yang, X.F.1    Weber, G.F.2    Cantor, H.3
  • 16
    • 0028922885 scopus 로고
    • Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice
    • Motoyama N, Wang F, Roth KA, et al. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 1995; 267:1506-10.
    • (1995) Science , vol.267 , pp. 1506-1510
    • Motoyama, N.1    Wang, F.2    Roth, K.A.3
  • 17
    • 0033635616 scopus 로고    scopus 로고
    • Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly
    • Wagner KU, Claudio E, Rucker EB 3rd, et al. Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly. Development 2000; 127:4949-58.
    • (2000) Development , vol.127 , pp. 4949-4958
    • Wagner, K.U.1    Claudio, E.2    Rucker III, E.B.3
  • 18
    • 4644350391 scopus 로고    scopus 로고
    • bcl-xL is critical for dendritic cell survival in vivo
    • Hon H, Rucker EB 3rd, Hennighausen L, Jacob J. bcl-xL is critical for dendritic cell survival in vivo. J Immunol 2004; 173:4425-32.
    • (2004) J Immunol , vol.173 , pp. 4425-4432
    • Hon, H.1    Rucker III, E.B.2    Hennighausen, L.3    Jacob, J.4
  • 19
    • 2942679279 scopus 로고    scopus 로고
    • A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells
    • Hou WS, Van Parijs L. A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells. Nat Immunol 2004; 5:583-9.
    • (2004) Nat Immunol , vol.5 , pp. 583-589
    • Hou, W.S.1    Van Parijs, L.2
  • 20
    • 0028970662 scopus 로고
    • Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice
    • Grillot DA, Merino R, Nunez G. Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice. J Exp Med 1995; 182:1973-83.
    • (1995) J Exp Med , vol.182 , pp. 1973-1983
    • Grillot, D.A.1    Merino, R.2    Nunez, G.3
  • 21
    • 0029031937 scopus 로고
    • Bclx regulates the survival of double-positive thymocytes
    • USA
    • Ma A, Pena JC, Chang B, et al. Bclx regulates the survival of double-positive thymocytes. Proc Natl Acad Sci USA 1995; 92:4763-7.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 4763-4767
    • Ma, A.1    Pena, J.C.2    Chang, B.3
  • 22
    • 0035999828 scopus 로고    scopus 로고
    • Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes
    • Guo J, Hawwari A, Li H, et al. Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. Nat Immunol 2002; 3:469-76.
    • (2002) Nat Immunol , vol.3 , pp. 469-476
    • Guo, J.1    Hawwari, A.2    Li, H.3
  • 23
    • 0034733039 scopus 로고    scopus 로고
    • Requirement for RORgamma in thymocyte survival and lymphoid organ development
    • Sun Z, Unutmaz D, Zou YR, et al. Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science 2000; 288:2369-73.
    • (2000) Science , vol.288 , pp. 2369-2373
    • Sun, Z.1    Unutmaz, D.2    Zou, Y.R.3
  • 24
    • 0348148880 scopus 로고    scopus 로고
    • Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
    • Opferman JT, Letai A, Beard C, et al. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature 2003; 426:671-6.
    • (2003) Nature , vol.426 , pp. 671-676
    • Opferman, J.T.1    Letai, A.2    Beard, C.3
  • 25
    • 13844319184 scopus 로고    scopus 로고
    • Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
    • Opferman JT, Iwasaki H, Ong CC, et al. Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science 2005; 307:1101-4.
    • (2005) Science , vol.307 , pp. 1101-1104
    • Opferman, J.T.1    Iwasaki, H.2    Ong, C.C.3
  • 26
    • 0033621956 scopus 로고    scopus 로고
    • The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x (L)
    • Chen C, Edelstein LC, Gelinas C. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x (L). Mol Cell Biol 2000; 20:2687-95.
    • (2000) Mol Cell Biol , vol.20 , pp. 2687-2695
    • Chen, C.1    Edelstein, L.C.2    Gelinas, C.3
  • 27
    • 0034674551 scopus 로고    scopus 로고
    • Al functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor
    • Duriez PJ, Wong F, Dorovini-Zis K, Shahidi R, Karsan A. Al functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor. J Biol Chem 2000; 275:18099-107.
    • (2000) J Biol Chem , vol.275 , pp. 18099-18107
    • Duriez, P.J.1    Wong, F.2    Dorovini-Zis, K.3    Shahidi, R.4    Karsan, A.5
  • 28
    • 0032543597 scopus 로고    scopus 로고
    • Functional dissection of Bfl-1, a Bcl-2 homolog: Anti-apoptosis, oncogene-cooperation and cell proliferation activities
    • D'Sa-Eipper C, Chinnadurai G. Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities. Oncogene 1998; 16:3105-14.
    • (1998) Oncogene , vol.16 , pp. 3105-3114
    • D'Sa-Eipper, C.1    Chinnadurai, G.2
  • 29
    • 0034712193 scopus 로고    scopus 로고
    • The CD40-inducible Bcl-2 family member Al protects B cells from antigen receptor-mediated apoptosis
    • Craxton A, Chuang PI, Shu G, Harlan JM, Clark EA. The CD40-inducible Bcl-2 family member Al protects B cells from antigen receptor-mediated apoptosis. Cell Immunol 2000; 200:56-62.
    • (2000) Cell Immunol , vol.200 , pp. 56-62
    • Craxton, A.1    Chuang, P.I.2    Shu, G.3    Harlan, J.M.4    Clark, E.A.5
  • 30
    • 20044368218 scopus 로고    scopus 로고
    • The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival
    • Mandal M, Borowski C, Palomero T, et al. The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J Exp Med 2005; 201:603-14.
    • (2005) J Exp Med , vol.201 , pp. 603-614
    • Mandal, M.1    Borowski, C.2    Palomero, T.3
  • 31
    • 0028946015 scopus 로고
    • Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K
    • Farrow SN, White JH, Martinou I, et al. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature 1995; 374:731-3.
    • (1995) Nature , vol.374 , pp. 731-733
    • Farrow, S.N.1    White, J.H.2    Martinou, I.3
  • 32
    • 0028986876 scopus 로고
    • Induction of apoptosis by the Bcl-2 homologue Bak
    • Chittenden T, Harrington EA, O'Connor R, et al. Induction of apoptosis by the Bcl-2 homologue Bak. Nature 1995; 374:733-6.
    • (1995) Nature , vol.374 , pp. 733-736
    • Chittenden, T.1    Harrington, E.A.2    O'Connor, R.3
  • 33
    • 0028904163 scopus 로고
    • Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak
    • Kiefer MC, Brauer MJ, Powers VC, et al. Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature 1995; 374:736-9.
    • (1995) Nature , vol.374 , pp. 736-739
    • Kiefer, M.C.1    Brauer, M.J.2    Powers, V.C.3
  • 34
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74:609-19.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 35
    • 0001587938 scopus 로고    scopus 로고
    • A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro
    • Hsu SY, Hsueh AJ. A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro. J Biol Chem 1998; 273:30139-46.
    • (1998) J Biol Chem , vol.273 , pp. 30139-30146
    • Hsu, S.Y.1    Hsueh, A.J.2
  • 37
    • 0034508217 scopus 로고    scopus 로고
    • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
    • Lindsten T, Ross AJ, King A, et al. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell 2000; 6:1389-99.
    • (2000) Mol Cell , vol.6 , pp. 1389-1399
    • Lindsten, T.1    Ross, A.J.2    King, A.3
  • 38
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001; 292:727-30.
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3
  • 40
    • 0036850312 scopus 로고    scopus 로고
    • Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
    • Kuwana T, Mackey MR, Perkins G, et al. Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 2002; 111:331-42.
    • (2002) Cell , vol.111 , pp. 331-342
    • Kuwana, T.1    Mackey, M.R.2    Perkins, G.3
  • 41
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91:479-89.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 42
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996; 86:147-57.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 43
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997; 90:405-13.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 45
    • 0030810926 scopus 로고    scopus 로고
    • X-linked IAP is a direct inhibitor of cell-death proteases
    • Deveraux QL, Takahashi R, Salvesen GS, Reed JC. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997; 388:300-4.
    • (1997) Nature , vol.388 , pp. 300-304
    • Deveraux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 46
    • 0035831021 scopus 로고    scopus 로고
    • Structural basis of caspase-7 inhibition by XIAP
    • Chai J, Shiozaki E, Srinivasula SM, et al. Structural basis of caspase-7 inhibition by XIAP. Cell 2001; 104:769-80.
    • (2001) Cell , vol.104 , pp. 769-780
    • Chai, J.1    Shiozaki, E.2    Srinivasula, S.M.3
  • 47
    • 0035831022 scopus 로고    scopus 로고
    • Structural basis of caspase inhibition by XIAP: Differential roles of the linker versus the BIR domain
    • Huang Y, Park YC, Rich RL, et al. Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain. Cell 2001; 104:781-90.
    • (2001) Cell , vol.104 , pp. 781-790
    • Huang, Y.1    Park, Y.C.2    Rich, R.L.3
  • 48
    • 0035831019 scopus 로고    scopus 로고
    • Structural basis for the inhibition of caspase-3 by XIAP
    • Riedl SJ, Renatus M, Schwarzenbacher R, et al. Structural basis for the inhibition of caspase-3 by XIAP. Cell 2001; 104:791-800.
    • (2001) Cell , vol.104 , pp. 791-800
    • Riedl, S.J.1    Renatus, M.2    Schwarzenbacher, R.3
  • 49
    • 0036088471 scopus 로고    scopus 로고
    • IAP proteins: Blocking the road to death's door
    • Salvesen GS, Duckett CS. IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol 2002; 3:401-10.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 401-410
    • Salvesen, G.S.1    Duckett, C.S.2
  • 50
    • 0034710649 scopus 로고    scopus 로고
    • Structural and biochemical basis of apoptotic activation by Smac/DIABLO
    • Chai J, Du C, Wu JW, et al. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 2000; 406:855-62.
    • (2000) Nature , vol.406 , pp. 855-862
    • Chai, J.1    Du, C.2    Wu, J.W.3
  • 51
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102:33-42.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 52
    • 0034700495 scopus 로고    scopus 로고
    • Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
    • Liu Z, Sun C, Olejniczak EL, et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature 2000; 408:1004-8.
    • (2000) Nature , vol.408 , pp. 1004-1008
    • Liu, Z.1    Sun, C.2    Olejniczak, E.L.3
  • 53
    • 0034616942 scopus 로고    scopus 로고
    • Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
    • Verhagen AM, Ekert PG, Pakusch M, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000; 102:43-53.
    • (2000) Cell , vol.102 , pp. 43-53
    • Verhagen, A.M.1    Ekert, P.G.2    Pakusch, M.3
  • 54
    • 0034785591 scopus 로고    scopus 로고
    • A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
    • Suzuki Y, Imai Y, Nakayama H, et al. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 2001; 8:613-21.
    • (2001) Mol Cell , vol.8 , pp. 613-621
    • Suzuki, Y.1    Imai, Y.2    Nakayama, H.3
  • 55
    • 0035811496 scopus 로고    scopus 로고
    • Endonuclease G is an apoptotic DNase when released from mitochondria
    • Li LY, Luo X, Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 2001; 412:95-9.
    • (2001) Nature , vol.412 , pp. 95-99
    • Li, L.Y.1    Luo, X.2    Wang, X.3
  • 56
    • 0035811511 scopus 로고    scopus 로고
    • Mitochondrial endonuclease G is important for apoptosis in C. elegans
    • Parrish J, Li L, Klotz K, et al. Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature 2001; 412:90-4.
    • (2001) Nature , vol.412 , pp. 90-94
    • Parrish, J.1    Li, L.2    Klotz, K.3
  • 57
    • 0035967169 scopus 로고    scopus 로고
    • Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
    • Joza N, Susin SA, Daugas E, et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001; 410:549-54.
    • (2001) Nature , vol.410 , pp. 549-554
    • Joza, N.1    Susin, S.A.2    Daugas, E.3
  • 58
    • 0033521741 scopus 로고    scopus 로고
    • Molecular characterization of mitochondrial apoptosis-inducing factor
    • Susin SA, Lorenzo HK, Zamzami N, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999; 397:441-6.
    • (1999) Nature , vol.397 , pp. 441-446
    • Susin, S.A.1    Lorenzo, H.K.2    Zamzami, N.3
  • 59
    • 0037159784 scopus 로고    scopus 로고
    • Mechanisms of ALF-mediated apoptotic DNA degradation in Caenorhabditis elegans
    • Wang X, Yang C, Chai J, Shi Y, Xue D. Mechanisms of ALF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science 2002; 298:1587-92.
    • (2002) Science , vol.298 , pp. 1587-1592
    • Wang, X.1    Yang, C.2    Chai, J.3    Shi, Y.4    Xue, D.5
  • 60
    • 0037067317 scopus 로고    scopus 로고
    • Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
    • Yu SW, Wang H, Poitras MF, et al. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002; 297:259-63.
    • (2002) Science , vol.297 , pp. 259-263
    • Yu, S.W.1    Wang, H.2    Poitras, M.F.3
  • 61
    • 0033635733 scopus 로고    scopus 로고
    • BH3-Only proteins-essential initiators of apoptotic cell death
    • Huang DC, Strasser A. BH3-Only proteins-essential initiators of apoptotic cell death. Cell 2000; 103:839-42.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.1    Strasser, A.2
  • 62
    • 0038021272 scopus 로고    scopus 로고
    • Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more
    • Marsden VS, Strasser A. Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more. Annu Rev Immunol 2003; 21:71-105.
    • (2003) Annu Rev Immunol , vol.21 , pp. 71-105
    • Marsden, V.S.1    Strasser, A.2
  • 63
    • 19944432123 scopus 로고    scopus 로고
    • Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function
    • Chen L, Willis SN, Wei A, et al. Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function. Mol Cell 2005; 17:393-403.
    • (2005) Mol Cell , vol.17 , pp. 393-403
    • Chen, L.1    Willis, S.N.2    Wei, A.3
  • 65
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998; 94:491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 66
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998; 94:481-90.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 67
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
    • Yang E, Zha J, Jockel J, et al. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 1995; 80:285-91.
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3
  • 68
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 1996; 87:619-28.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 69
    • 0037148840 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
    • Bouillet P, Purton JF, Godfrey DI, et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 2002; 415:922-6.
    • (2002) Nature , vol.415 , pp. 922-926
    • Bouillet, P.1    Purton, J.F.2    Godfrey, D.I.3
  • 70
    • 0242410719 scopus 로고    scopus 로고
    • p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
    • Villunger A, Michalak EM, Coultas L, et al. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 2003; 302:1036-8.
    • (2003) Science , vol.302 , pp. 1036-1038
    • Villunger, A.1    Michalak, E.M.2    Coultas, L.3
  • 71
    • 0033607006 scopus 로고    scopus 로고
    • Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
    • Yin XM, Wang K, Gross A, et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 1999; 400:886-91.
    • (1999) Nature , vol.400 , pp. 886-891
    • Yin, X.M.1    Wang, K.2    Gross, A.3
  • 72
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano K, Vousden KH. PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 2001; 7:683-94.
    • (2001) Mol Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 73
    • 0034640281 scopus 로고    scopus 로고
    • Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
    • Oda E, Ohki R, Murasawa H, et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000; 288:1053-8.
    • (2000) Science , vol.288 , pp. 1053-1058
    • Oda, E.1    Ohki, R.2    Murasawa, H.3
  • 75
    • 0037452759 scopus 로고    scopus 로고
    • PUMA mediates the apoptotic response to p53 in colorectal cancer cells
    • U S A
    • Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci U S A 2003; 100:1931-6.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 1931-1936
    • Yu, J.1    Wang, Z.2    Kinzler, K.W.3    Vogelstein, B.4    Zhang, L.5
  • 76
    • 0037513376 scopus 로고    scopus 로고
    • p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation
    • Schuler M, Maurer U, Goldstein JC, et al. p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation. Cell Death Differ 2003; 10:451-60.
    • (2003) Cell Death Differ , vol.10 , pp. 451-460
    • Schuler, M.1    Maurer, U.2    Goldstein, J.C.3
  • 77
    • 0842347424 scopus 로고    scopus 로고
    • Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death
    • Coultas L, Bouillet P, Stanley EG, et al. Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death. Mol Cell Biol 2004; 24:1570-81.
    • (2004) Mol Cell Biol , vol.24 , pp. 1570-1581
    • Coultas, L.1    Bouillet, P.2    Stanley, E.G.3
  • 78
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001; 104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 79
    • 5644222552 scopus 로고    scopus 로고
    • Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction
    • Muppidi JR, Tschopp J, Siegel RM. Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 2004; 21:461-5.
    • (2004) Immunity , vol.21 , pp. 461-465
    • Muppidi, J.R.1    Tschopp, J.2    Siegel, R.M.3
  • 82
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995; 81:505-12.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 83
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
    • Hsu H, Xiong J, Goeddel DV. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 1995; 81:495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 84
    • 0031406386 scopus 로고    scopus 로고
    • Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
    • Chaudhary PM, Eby M, Jasmin A, et al. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 1997; 7:821-30.
    • (1997) Immunity , vol.7 , pp. 821-830
    • Chaudhary, P.M.1    Eby, M.2    Jasmin, A.3
  • 85
    • 0031405585 scopus 로고    scopus 로고
    • TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB
    • Schneider P, Thome M, Burns K, et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB. Immunity 1997; 7:831-6.
    • (1997) Immunity , vol.7 , pp. 831-836
    • Schneider, P.1    Thome, M.2    Burns, K.3
  • 86
    • 10544236916 scopus 로고    scopus 로고
    • Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
    • Chinnaiyan AM, O'Rourke K, Yu GL, et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996; 274:990-2.
    • (1996) Science , vol.274 , pp. 990-992
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Yu, G.L.3
  • 87
    • 0032563275 scopus 로고    scopus 로고
    • Identification and functional characterization of DR6, a novel death domain-containing TNF receptor
    • Pan G, Bauer JH, Haridas V, et al. Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. FEBS Lett 1998; 431:351-6.
    • (1998) FEBS Lett , vol.431 , pp. 351-356
    • Pan, G.1    Bauer, J.H.2    Haridas, V.3
  • 88
    • 0029006893 scopus 로고
    • Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
    • Rieux-Laucat F, Le Deist F, Hivroz C, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995; 268:1347-9.
    • (1995) Science , vol.268 , pp. 1347-1349
    • Rieux-Laucat, F.1    Le Deist, F.2    Hivroz, C.3
  • 89
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992; 356:314-7.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 90
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo M, Chan KM, Hornung F, et al. Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol 1999; 17:221-53.
    • (1999) Annu Rev Immunol , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, K.M.2    Hornung, F.3
  • 91
    • 0028980902 scopus 로고
    • Fas and Fas ligand: Lpr and gld mutations
    • Nagata S, Suda T. Fas and Fas ligand: lpr and gld mutations. Immunol Today 1995; 16:39-43.
    • (1995) Immunol Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 92
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel FC, Hellbardt S, Behrmann I, et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. Embo J 1995; 14:5579-88.
    • (1995) Embo J , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3
  • 93
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
    • Boldin MP, Goncharov TM, Goltsev YV, Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 1996; 85:803-15.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 94
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death - Inducing signaling complex
    • Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death - inducing signaling complex. Cell 1996; 85:817-27.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1    Chinnaiyan, A.M.2    Kischkel, F.C.3
  • 95
    • 0030925774 scopus 로고    scopus 로고
    • FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
    • Medema JP, Scaffidi C, Kischkel FC, et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). Embo J 1997; 16:2794-804.
    • (1997) Embo J , vol.16 , pp. 2794-2804
    • Medema, J.P.1    Scaffidi, C.2    Kischkel, F.C.3
  • 96
    • 0031615875 scopus 로고    scopus 로고
    • Autoproteolytic activation of pro-caspases by oligomerization
    • Yang X, Chang HY, Baltimore D. Autoproteolytic activation of pro-caspases by oligomerization. Mol Cell 1998; 1:319-25.
    • (1998) Mol Cell , vol.1 , pp. 319-325
    • Yang, X.1    Chang, H.Y.2    Baltimore, D.3
  • 97
    • 0030800070 scopus 로고    scopus 로고
    • Inhibition of death receptor signals by cellular FLIP
    • Irmler M, Thome M, Hahne M, et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997; 388:190-5.
    • (1997) Nature , vol.388 , pp. 190-195
    • Irmler, M.1    Thome, M.2    Hahne, M.3
  • 98
    • 0030746740 scopus 로고    scopus 로고
    • Casper is a FADD- and caspase-related inducer of apoptosis
    • Shu HB, Halpin DR, Goeddel DV. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 1997; 6:751-63.
    • (1997) Immunity , vol.6 , pp. 751-763
    • Shu, H.B.1    Halpin, D.R.2    Goeddel, D.V.3
  • 99
    • 0030841911 scopus 로고    scopus 로고
    • I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
    • Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J Biol Chem 1997; 272:17255-7.
    • (1997) J Biol Chem , vol.272 , pp. 17255-17257
    • Hu, S.1    Vincenz, C.2    Ni, J.3    Gentz, R.4    Dixit, V.M.5
  • 100
    • 0030877440 scopus 로고    scopus 로고
    • CASH, a novel caspase homologue with death effector domains
    • Goltsev YV, Kovalenko AV, Arnold E, et al. CASH, a novel caspase homologue with death effector domains. J Biol Chem 1997; 272:19641-4.
    • (1997) J Biol Chem , vol.272 , pp. 19641-19644
    • Goltsev, Y.V.1    Kovalenko, A.V.2    Arnold, E.3
  • 101
    • 0030810981 scopus 로고    scopus 로고
    • FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis
    • Srinivasula SM, Ahmad M, Ottilie S, et al. FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J Biol Chem 1997; 272:18542-5.
    • (1997) J Biol Chem , vol.272 , pp. 18542-18545
    • Srinivasula, S.M.1    Ahmad, M.2    Ottilie, S.3
  • 102
    • 0030758315 scopus 로고    scopus 로고
    • MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death
    • U S A
    • Han DK, Chaudhary PM, Wright ME, et al. MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci U S A 1997; 94:11333-8.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 11333-11338
    • Han, D.K.1    Chaudhary, P.M.2    Wright, M.E.3
  • 103
    • 0030961084 scopus 로고    scopus 로고
    • CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis
    • U S A
    • Inohara N, Koseki T, Hu Y, Chen S, Nunez G. CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis. Proc Natl Acad Sci U S A 1997; 94:10717-22.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 10717-10722
    • Inohara, N.1    Koseki, T.2    Hu, Y.3    Chen, S.4    Nunez, G.5
  • 104
    • 7344220967 scopus 로고    scopus 로고
    • Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
    • Rasper DM, Vaillancourt JP, Hadano S, et al. Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ 1998; 5:271-88.
    • (1998) Cell Death Differ , vol.5 , pp. 271-288
    • Rasper, D.M.1    Vaillancourt, J.P.2    Hadano, S.3
  • 105
    • 0035496099 scopus 로고    scopus 로고
    • Regulation of lymphocyte proliferation and death by FLIP
    • Thome M, Tschopp J. Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol 2001; 1:50-8.
    • (2001) Nat Rev Immunol , vol.1 , pp. 50-58
    • Thome, M.1    Tschopp, J.2
  • 106
    • 0037099678 scopus 로고    scopus 로고
    • c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
    • Chang DW, Xing Z, Pan Y, et al. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. Embo J 2002; 21:3704-14.
    • (2002) Embo J , vol.21 , pp. 3704-3714
    • Chang, D.W.1    Xing, Z.2    Pan, Y.3
  • 107
    • 0033662341 scopus 로고    scopus 로고
    • Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
    • Yeh WC, Itie A, Elia AJ, et al. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000; 12:633-42.
    • (2000) Immunity , vol.12 , pp. 633-642
    • Yeh, W.C.1    Itie, A.2    Elia, A.J.3
  • 108
    • 0029949257 scopus 로고    scopus 로고
    • TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
    • Hsu H, Huang J, Shu HB, Baichwal V, Goeddel DV. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 1996; 4:387-96.
    • (1996) Immunity , vol.4 , pp. 387-396
    • Hsu, H.1    Huang, J.2    Shu, H.B.3    Baichwal, V.4    Goeddel, D.V.5
  • 109
    • 0032033132 scopus 로고    scopus 로고
    • The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
    • Kelliher MA, Grimm S, Ishida Y, et al. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 1998; 8:297-303.
    • (1998) Immunity , vol.8 , pp. 297-303
    • Kelliher, M.A.1    Grimm, S.2    Ishida, Y.3
  • 110
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu H, Shu HB, Pan MG, Goeddel DV. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 1996; 84:299-308.
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3    Goeddel, D.V.4
  • 111
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
    • Liu ZG, Hsu H, Goeddel DV, Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 1996; 87:565-76.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 113
    • 0346435107 scopus 로고    scopus 로고
    • Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B
    • Wang Q, Wang X, Evers BM. Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B. J Biol Chem 2003; 278:51091-9.
    • (2003) J Biol Chem , vol.278 , pp. 51091-51099
    • Wang, Q.1    Wang, X.2    Evers, B.M.3
  • 114
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003; 114:181-90.
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 115
    • 0038742813 scopus 로고    scopus 로고
    • Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation
    • Legler DF, Micheau O, Doucey MA, Tschopp J, Bron C. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity 2003; 18:655-64.
    • (2003) Immunity , vol.18 , pp. 655-664
    • Legler, D.F.1    Micheau, O.2    Doucey, M.A.3    Tschopp, J.4    Bron, C.5
  • 116
    • 0042197417 scopus 로고    scopus 로고
    • The TNF receptor 1: A split personality complex
    • Barnhart BC, Peter ME. The TNF receptor 1: a split personality complex. Cell 2003; 114:148-50.
    • (2003) Cell , vol.114 , pp. 148-150
    • Barnhart, B.C.1    Peter, M.E.2
  • 117
    • 0037815277 scopus 로고    scopus 로고
    • Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
    • Harper N, Hughes M, MacFarlane M, Cohen GM. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. J Biol Chem 2003; 278:25534-41.
    • (2003) J Biol Chem , vol.278 , pp. 25534-25541
    • Harper, N.1    Hughes, M.2    MacFarlane, M.3    Cohen, G.M.4
  • 118
    • 0033214236 scopus 로고    scopus 로고
    • Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
    • Lin Y, Devin A, Rodriguez Y, Liu ZG. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 1999; 13:2514-26.
    • (1999) Genes Dev , vol.13 , pp. 2514-2526
    • Lin, Y.1    Devin, A.2    Rodriguez, Y.3    Liu, Z.G.4
  • 119
    • 0141953270 scopus 로고    scopus 로고
    • A JNK-dependent pathway is required for TNFalpha-induced apoptosis
    • Deng Y, Ren X, Yang L, Lin Y, Wu X. A JNK-dependent pathway is required for TNFalpha-induced apoptosis. Cell 2003; 115:61-70.
    • (2003) Cell , vol.115 , pp. 61-70
    • Deng, Y.1    Ren, X.2    Yang, L.3    Lin, Y.4    Wu, X.5
  • 120
    • 14844327760 scopus 로고    scopus 로고
    • Reactive Oxygen Species Promote TNFalpha-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
    • Kamata H, Honda SI, Maeda S, et al. Reactive Oxygen Species Promote TNFalpha-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases. Cell 2005; 120:649-661.
    • (2005) Cell , vol.120 , pp. 649-661
    • Kamata, H.1    Honda, S.I.2    Maeda, S.3
  • 121
    • 0035808769 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
    • Sabapathy K, Kallunki T, David JP, et al. c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation. J Exp Med 2001; 193:317-28.
    • (2001) J Exp Med , vol.193 , pp. 317-328
    • Sabapathy, K.1    Kallunki, T.2    David, J.P.3
  • 122
    • 4444341939 scopus 로고    scopus 로고
    • Compartmentalization of TNF receptor 1 signaling: Internalized TNF receptosomes as death signaling vesicles
    • Schneider-Brachert W, Tchikov V, Neumeyer J, et al. Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. Immunity 2004; 21:415-28.
    • (2004) Immunity , vol.21 , pp. 415-428
    • Schneider-Brachert, W.1    Tchikov, V.2    Neumeyer, J.3
  • 123
    • 0033581935 scopus 로고    scopus 로고
    • Selecting and maintaining a diverse T-cell repertoire
    • Goldrath AW, Bevan MJ. Selecting and maintaining a diverse T-cell repertoire. Nature 1999; 402:255-62.
    • (1999) Nature , vol.402 , pp. 255-262
    • Goldrath, A.W.1    Bevan, M.J.2
  • 125
    • 0027491232 scopus 로고
    • Control points in early T-cell development
    • Godfrey DI, Zlotnik A. Control points in early T-cell development. Immunol Today 1993; 14:547-53.
    • (1993) Immunol Today , vol.14 , pp. 547-553
    • Godfrey, D.I.1    Zlotnik, A.2
  • 126
    • 0141989773 scopus 로고    scopus 로고
    • Gated importation of prothymocytes by adult mouse thymus is coordinated with their periodic mobilization from bone marrow
    • Donskoy E, Foss D, Goldschneider I. Gated importation of prothymocytes by adult mouse thymus is coordinated with their periodic mobilization from bone marrow. J Immunol 2003; 171:3568-75.
    • (2003) J Immunol , vol.171 , pp. 3568-3575
    • Donskoy, E.1    Foss, D.2    Goldschneider, I.3
  • 127
    • 0035808785 scopus 로고    scopus 로고
    • The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice
    • Foss DL, Donskoy E, Goldschneider I. The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice. J Exp Med 2001; 193:365-74.
    • (2001) J Exp Med , vol.193 , pp. 365-374
    • Foss, D.L.1    Donskoy, E.2    Goldschneider, I.3
  • 128
    • 4344640158 scopus 로고    scopus 로고
    • The ins and outs of CCR7 in the thymus
    • Witt CM, Robey EA. The ins and outs of CCR7 in the thymus. J Exp Med 2004; 200:405-9.
    • (2004) J Exp Med , vol.200 , pp. 405-409
    • Witt, C.M.1    Robey, E.A.2
  • 129
    • 4344574151 scopus 로고    scopus 로고
    • Thymic T cell development and progenitor localization depend on CCR7
    • Misslitz A, Pabst O, Hintzen G, et al. Thymic T cell development and progenitor localization depend on CCR7. J Exp Med 2004; 200:481-91.
    • (2004) J Exp Med , vol.200 , pp. 481-491
    • Misslitz, A.1    Pabst, O.2    Hintzen, G.3
  • 130
    • 0027988545 scopus 로고
    • Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
    • Peschon JJ, Morrissey PJ, Grabstein KH, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 1994; 180:1955-60.
    • (1994) J Exp Med , vol.180 , pp. 1955-1960
    • Peschon, J.J.1    Morrissey, P.J.2    Grabstein, K.H.3
  • 131
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • von Freeden-Jeffry U, Vieira P, Lucian LA, et al. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 1995; 181:1519-26.
    • (1995) J Exp Med , vol.181 , pp. 1519-1526
    • Von Freeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3
  • 132
    • 0034161282 scopus 로고    scopus 로고
    • FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor
    • Newton K, Harris AW, Strasser A. FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor. Embo J 2000; 19:931-41.
    • (2000) Embo J , vol.19 , pp. 931-941
    • Newton, K.1    Harris, A.W.2    Strasser, A.3
  • 133
    • 0034665305 scopus 로고    scopus 로고
    • Spontaneous thymocyte apoptosis is regulated by a mitochondrion-mediated signaling pathway
    • Zhang J, Mikecz K, Finnegan A, Glant TT. Spontaneous thymocyte apoptosis is regulated by a mitochondrion-mediated signaling pathway. J Immunol 2000; 165:2970-4.
    • (2000) J Immunol , vol.165 , pp. 2970-2974
    • Zhang, J.1    Mikecz, K.2    Finnegan, A.3    Glant, T.T.4
  • 134
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, Metcalf D, Huang DC, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999; 286:1735-8.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3
  • 135
    • 0037057629 scopus 로고    scopus 로고
    • Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
    • Marsden VS, O'Connor L, O'Reilly LA, et al. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature 2002; 419:634-7.
    • (2002) Nature , vol.419 , pp. 634-637
    • Marsden, V.S.1    O'Connor, L.2    O'Reilly, L.A.3
  • 136
    • 0141814654 scopus 로고    scopus 로고
    • Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist
    • U S A
    • Rosen H, Alfonso C, Surh CD, McHeyzer-Williams MG. Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist. Proc Natl Acad Sci U S A 2003; 100:10907-12.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 10907-10912
    • Rosen, H.1    Alfonso, C.2    Surh, C.D.3    McHeyzer-Williams, M.G.4
  • 137
    • 4344668118 scopus 로고    scopus 로고
    • CCR7 signals are essential for cortex-medulla migration of developing thymocytes
    • Ueno T, Saito F, Gray DH, et al. CCR7 signals are essential for cortex-medulla migration of developing thymocytes. J Exp Med 2004; 200:493-505.
    • (2004) J Exp Med , vol.200 , pp. 493-505
    • Ueno, T.1    Saito, F.2    Gray, D.H.3
  • 138
    • 23744456144 scopus 로고    scopus 로고
    • An essential role for c-FLIP in the efficient development of mature T lymphocytes
    • Zhang N, He YW. An essential role for c-FLIP in the efficient development of mature T lymphocytes. J Exp Med 2005; 202:395-404.
    • (2005) J Exp Med , vol.202 , pp. 395-404
    • Zhang, N.1    He, Y.W.2
  • 139
    • 0038725685 scopus 로고    scopus 로고
    • Negative selection - Clearing out the bad apples from the T-cell repertoire
    • Palmer E. Negative selection - clearing out the bad apples from the T-cell repertoire. Nat Rev Immunol 2003; 3:383-91.
    • (2003) Nat Rev Immunol , vol.3 , pp. 383-391
    • Palmer, E.1
  • 140
    • 0036630358 scopus 로고    scopus 로고
    • The thymus and negative selection
    • Sprent J, Kishimoto H. The thymus and negative selection. Immunol Rev 2002; 185:126-35.
    • (2002) Immunol Rev , vol.185 , pp. 126-135
    • Sprent, J.1    Kishimoto, H.2
  • 141
    • 0025231503 scopus 로고
    • Developmental biology of T cells in T cell-receptor transgenic mice
    • von Boehmer H. Developmental biology of T cells in T cell-receptor transgenic mice. Annu Rev Immunol 1990; 8:531-56.
    • (1990) Annu Rev Immunol , vol.8 , pp. 531-556
    • Von Boehmer, H.1
  • 142
    • 22344450566 scopus 로고    scopus 로고
    • The timing of TCR {alpha} expression critically influences T cell development and selection
    • Baldwin TA, Sandau MM, Jameson SC, Hogquist KA. The timing of TCR {alpha} expression critically influences T cell development and selection. J Exp Med 2005; 202:111-21.
    • (2005) J Exp Med , vol.202 , pp. 111-121
    • Baldwin, T.A.1    Sandau, M.M.2    Jameson, S.C.3    Hogquist, K.A.4
  • 143
    • 0031054632 scopus 로고    scopus 로고
    • Negative selection in the thymus includes semimature T cells
    • Kishimoto H, Sprent J. Negative selection in the thymus includes semimature T cells. J Exp Med 1997; 185:263-71.
    • (1997) J Exp Med , vol.185 , pp. 263-271
    • Kishimoto, H.1    Sprent, J.2
  • 144
    • 1642473196 scopus 로고    scopus 로고
    • Developmental status of CD4-CD8+ and CD4+CD8- thymocytes with medium expression of CD3
    • Sheard MA, Liu C, Takahama Y. Developmental status of CD4-CD8+ and CD4+CD8- thymocytes with medium expression of CD3. Eur J Immunol 2004; 34:25-35.
    • (2004) Eur J Immunol , vol.34 , pp. 25-35
    • Sheard, M.A.1    Liu, C.2    Takahama, Y.3
  • 145
    • 4544258485 scopus 로고    scopus 로고
    • Self-representation in the thymus: An extended view
    • Kyewski B, Derbinski J. Self-representation in the thymus: an extended view. Nat Rev Immunol 2004; 4:688-98.
    • (2004) Nat Rev Immunol , vol.4 , pp. 688-698
    • Kyewski, B.1    Derbinski, J.2
  • 146
    • 0032482160 scopus 로고    scopus 로고
    • A role for Fas in negative selection of thymocytes in vivo
    • Kishimoto H, Surh CD, Sprent J. A role for Fas in negative selection of thymocytes in vivo. J Exp Med 1998; 187:1427-38.
    • (1998) J Exp Med , vol.187 , pp. 1427-1438
    • Kishimoto, H.1    Surh, C.D.2    Sprent, J.3
  • 147
    • 0033213877 scopus 로고    scopus 로고
    • Cutting edge: Thymic selection and autoreactivity are regulated by multiple coreceptors involved in T cell activation
    • Page DM. Cutting edge: thymic selection and autoreactivity are regulated by multiple coreceptors involved in T cell activation. J Immunol 1999; 163:3577-81.
    • (1999) J Immunol , vol.163 , pp. 3577-3581
    • Page, D.M.1
  • 148
    • 0027297663 scopus 로고
    • Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
    • Pfeffer K, Matsuyama T, Kundig TM, et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993; 73:457-67.
    • (1993) Cell , vol.73 , pp. 457-467
    • Pfeffer, K.1    Matsuyama, T.2    Kundig, T.M.3
  • 149
    • 0028063303 scopus 로고
    • Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice
    • Erickson SL, de Sauvage FJ, Kikly K, et al. Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice. Nature 1994; 372:560-3.
    • (1994) Nature , vol.372 , pp. 560-563
    • Erickson, S.L.1    De Sauvage, F.J.2    Kikly, K.3
  • 150
    • 0031883138 scopus 로고    scopus 로고
    • TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection
    • Page DM, Roberts EM, Peschon JJ, Hedrick SM. TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection. J Immunol 1998; 160:120-33.
    • (1998) J Immunol , vol.160 , pp. 120-133
    • Page, D.M.1    Roberts, E.M.2    Peschon, J.J.3    Hedrick, S.M.4
  • 151
    • 0042624821 scopus 로고    scopus 로고
    • Normal thymocyte negative selection in TRAIL-deficient mice
    • Cretney E, Uldrich AP, Berzins SP, et al. Normal thymocyte negative selection in TRAIL-deficient mice. J Exp Med 2003; 198:491-6.
    • (2003) J Exp Med , vol.198 , pp. 491-496
    • Cretney, E.1    Uldrich, A.P.2    Berzins, S.P.3
  • 153
    • 10344260656 scopus 로고    scopus 로고
    • TRAIL-R as a negative regulator of innate immune cell responses
    • Diehl GE, Yue HH, Hsieh K, et al TRAIL-R as a negative regulator of innate immune cell responses. Immunity 2004; 21:877-89.
    • (2004) Immunity , vol.21 , pp. 877-889
    • Diehl, G.E.1    Yue, H.H.2    Hsieh, K.3
  • 155
    • 0035027854 scopus 로고    scopus 로고
    • DR3 regulates negative selection during thymocyte development
    • Wang EC, Thern A, Denzel A, et al. DR3 regulates negative selection during thymocyte development. Mol Cell Biol 2001; 21:3451-61.
    • (2001) Mol Cell Biol , vol.21 , pp. 3451-3461
    • Wang, E.C.1    Thern, A.2    Denzel, A.3
  • 156
    • 2342458871 scopus 로고    scopus 로고
    • Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling
    • U S A
    • Villunger A, Marsden VS, Zhan Y, et al. Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling. Proc Natl Acad Sci U S A 2004; 101:7052-7.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 7052-7057
    • Villunger, A.1    Marsden, V.S.2    Zhan, Y.3
  • 157
    • 0036499206 scopus 로고    scopus 로고
    • The apoptotic protease-activating factor 1-mediated pathway of apoptosis is dispensable for negative selection of thymocytes
    • Hara H, Takeda A, Takeuchi M, et al. The apoptotic protease-activating factor 1-mediated pathway of apoptosis is dispensable for negative selection of thymocytes. J Immunol 2002; 168:2288-95.
    • (2002) J Immunol , vol.168 , pp. 2288-2295
    • Hara, H.1    Takeda, A.2    Takeuchi, M.3
  • 158
    • 0033521530 scopus 로고    scopus 로고
    • Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor
    • Izquierdo M, Grandien A, Criado LM, et al. Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor. Embo J 1999; 18:156-66.
    • (1999) Embo J , vol.18 , pp. 156-166
    • Izquierdo, M.1    Grandien, A.2    Criado, L.M.3
  • 159
    • 0034655149 scopus 로고    scopus 로고
    • Caspase enzyme activity is not essential for apoptosis during thymocyte development
    • Doerfler P, Forbush KA, Perlmutter RM. Caspase enzyme activity is not essential for apoptosis during thymocyte development. J Immunol 2000; 164:4071-9.
    • (2000) J Immunol , vol.164 , pp. 4071-4079
    • Doerfler, P.1    Forbush, K.A.2    Perlmutter, R.M.3
  • 160
    • 5844320555 scopus 로고    scopus 로고
    • Homeostasis of alpha beta TCR+ T cells
    • Marrack P, Bender J, Hildeman D, et al. Homeostasis of alpha beta TCR+ T cells. Nat Immunol 2000; 1:107-11.
    • (2000) Nat Immunol , vol.1 , pp. 107-111
    • Marrack, P.1    Bender, J.2    Hildeman, D.3
  • 161
    • 0034080178 scopus 로고    scopus 로고
    • Population biology of lymphocytes: The flight for survival
    • Freitas AA, Rocha B. Population biology of lymphocytes: the flight for survival. Annu Rev Immunol 2000; 18:83-111.
    • (2000) Annu Rev Immunol , vol.18 , pp. 83-111
    • Freitas, A.A.1    Rocha, B.2
  • 162
    • 0034698931 scopus 로고    scopus 로고
    • Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
    • Goldrath AW, Bogatzki LY, Bevan MJ. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J Exp Med 2000; 192:557-64.
    • (2000) J Exp Med , vol.192 , pp. 557-564
    • Goldrath, A.W.1    Bogatzki, L.Y.2    Bevan, M.J.3
  • 163
    • 0030775139 scopus 로고    scopus 로고
    • Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
    • Kirberg J, Berns A, von Boehmer H. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules. J Exp Med 1997; 186:1269-75.
    • (1997) J Exp Med , vol.186 , pp. 1269-1275
    • Kirberg, J.1    Berns, A.2    Von Boehmer, H.3
  • 164
    • 0035471754 scopus 로고    scopus 로고
    • Interleukin-7: Master regulator of peripheral T-cell homeostasis?
    • Fry TJ, Mackall CL. Interleukin-7: master regulator of peripheral T-cell homeostasis? Trends Immunol 2001; 22:564-71.
    • (2001) Trends Immunol , vol.22 , pp. 564-571
    • Fry, T.J.1    Mackall, C.L.2
  • 165
    • 2642714166 scopus 로고    scopus 로고
    • MHC class I is required for peripheral accumulation of CD8+ thymic emigrants
    • Nesic D, Vukmanovic S. MHC class I is required for peripheral accumulation of CD8+ thymic emigrants. J Immunol 1998; 160:3705-12.
    • (1998) J Immunol , vol.160 , pp. 3705-3712
    • Nesic, D.1    Vukmanovic, S.2
  • 166
    • 0033136944 scopus 로고    scopus 로고
    • Designing and maintaining the mature TCR repertoire: The continuum of self-peptide:self-MHC complex recognition
    • Viret C, Wong FS, Janeway CA, Jr. Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition. Immunity 1999; 10:559-68.
    • (1999) Immunity , vol.10 , pp. 559-568
    • Viret, C.1    Wong, F.S.2    Janeway Jr., C.A.3
  • 167
    • 0030849637 scopus 로고    scopus 로고
    • Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
    • Rooke R, Waltzinger C, Benoist C, Mathis D. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. Immunity 1997; 7:123-34.
    • (1997) Immunity , vol.7 , pp. 123-134
    • Rooke, R.1    Waltzinger, C.2    Benoist, C.3    Mathis, D.4
  • 168
    • 0030249953 scopus 로고    scopus 로고
    • MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span
    • Takeda S, Rodewald HR, Arakawa H, Bluethmann H, Shimizu T. MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity 1996; 5:217-28.
    • (1996) Immunity , vol.5 , pp. 217-228
    • Takeda, S.1    Rodewald, H.R.2    Arakawa, H.3    Bluethmann, H.4    Shimizu, T.5
  • 169
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns KS, Kieper WC, Jameson SC, Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 2000; 1:426-32.
    • (2000) Nat Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 170
    • 0035902513 scopus 로고    scopus 로고
    • IL-7 is critical for homeostatic proliferation and survival of naive T cells
    • U S A
    • Tan JT, Dudl E, LeRoy E, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A 2001; 98:8732-7.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 8732-8737
    • Tan, J.T.1    Dudl, E.2    LeRoy, E.3
  • 171
    • 0033517155 scopus 로고    scopus 로고
    • CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection
    • Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med 1999; 190:367-74.
    • (1999) J Exp Med , vol.190 , pp. 367-374
    • Bender, J.1    Mitchell, T.2    Kappler, J.3    Marrack, P.4
  • 172
    • 0033180491 scopus 로고    scopus 로고
    • The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
    • Ernst B, Lee DS, Chang JM, Sprent J, Surh CD. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 1999; 11:173-81.
    • (1999) Immunity , vol.11 , pp. 173-181
    • Ernst, B.1    Lee, D.S.2    Chang, J.M.3    Sprent, J.4    Surh, C.D.5
  • 173
    • 0033180494 scopus 로고    scopus 로고
    • Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts
    • Goldrath AW, Bevan MJ. Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts. Immunity 1999; 11:183-90.
    • (1999) Immunity , vol.11 , pp. 183-190
    • Goldrath, A.W.1    Bevan, M.J.2
  • 174
    • 0036219154 scopus 로고    scopus 로고
    • CD8(+) T-cell homeostasis after infection: Setting the 'curve'
    • Badovinac VP, Harty JT. CD8(+) T-cell homeostasis after infection: setting the 'curve'. Microbes Infect 2002; 4:441-7.
    • (2002) Microbes Infect , vol.4 , pp. 441-447
    • Badovinac, V.P.1    Harty, J.T.2
  • 175
    • 0036550559 scopus 로고    scopus 로고
    • Effector and memory T-cell differentiation: Implications for vaccine development
    • Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol 2002; 2:251-62.
    • (2002) Nat Rev Immunol , vol.2 , pp. 251-262
    • Kaech, S.M.1    Wherry, E.J.2    Ahmed, R.3
  • 176
    • 0032482337 scopus 로고    scopus 로고
    • A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
    • Ridge JP, Di Rosa F, Matzinger P A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 1998; 393:474-8.
    • (1998) Nature , vol.393 , pp. 474-478
    • Ridge, J.P.1    Di Rosa, F.2    Matzinger, P.3
  • 177
    • 0032482356 scopus 로고    scopus 로고
    • Help for cytotoxic-T-cell responses is mediated by CD40 signalling
    • Bennett SR, Carbone FR, Karamalis F, et al. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 1998; 393:478-80.
    • (1998) Nature , vol.393 , pp. 478-480
    • Bennett, S.R.1    Carbone, F.R.2    Karamalis, F.3
  • 178
    • 0037456367 scopus 로고    scopus 로고
    • CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
    • Janssen EM, Lemmens EE, Wolfe T, et al. CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature 2003; 421:852-6.
    • (2003) Nature , vol.421 , pp. 852-856
    • Janssen, E.M.1    Lemmens, E.E.2    Wolfe, T.3
  • 179
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun JC, Bevan MJ. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003; 300:339-42.
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 180
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock DJ, Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003; 300:337-9.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 181
    • 4644271443 scopus 로고    scopus 로고
    • CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection
    • Sun JC, Williams MA, Bevan MJ. CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection. Nat Immunol 2004; 5:927-33.
    • (2004) Nat Immunol , vol.5 , pp. 927-933
    • Sun, J.C.1    Williams, M.A.2    Bevan, M.J.3
  • 182
    • 3543099130 scopus 로고    scopus 로고
    • Helping the CD8(+) T-cell response
    • Bevan MJ. Helping the CD8(+) T-cell response. Nat Rev Immunol 2004; 4:595-602.
    • (2004) Nat Rev Immunol , vol.4 , pp. 595-602
    • Bevan, M.J.1
  • 183
    • 14544288632 scopus 로고    scopus 로고
    • CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
    • Janssen EM, Droin NM, Lemmens EE, et al. CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature 2005; 434:88-93.
    • (2005) Nature , vol.434 , pp. 88-93
    • Janssen, E.M.1    Droin, N.M.2    Lemmens, E.E.3
  • 184
    • 0035348175 scopus 로고    scopus 로고
    • Memory CD8+ T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells
    • Kaech SM, Ahmed R. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat Immunol 2001; 2:415-22.
    • (2001) Nat Immunol , vol.2 , pp. 415-422
    • Kaech, S.M.1    Ahmed, R.2
  • 185
    • 0035344684 scopus 로고    scopus 로고
    • The CD8 response on autopilot
    • Bevan MJ, Fink PJ. The CD8 response on autopilot. Nat Immunol 2001; 2:381-2.
    • (2001) Nat Immunol , vol.2 , pp. 381-382
    • Bevan, M.J.1    Fink, P.J.2
  • 186
    • 0035348246 scopus 로고    scopus 로고
    • Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
    • van Stipdonk MJ, Lemmens EE, Schoenberger SP. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat Immunol 2001; 2:423-9.
    • (2001) Nat Immunol , vol.2 , pp. 423-429
    • Van Stipdonk, M.J.1    Lemmens, E.E.2    Schoenberger, S.P.3
  • 187
    • 0034671979 scopus 로고    scopus 로고
    • Early programming of T cell populations responding to bacterial infection
    • Mercado R, Vijh S, Allen SE, et al. Early programming of T cell populations responding to bacterial infection. J Immunol 2000; 165:6833-9.
    • (2000) J Immunol , vol.165 , pp. 6833-6839
    • Mercado, R.1    Vijh, S.2    Allen, S.E.3
  • 188
    • 0035873191 scopus 로고    scopus 로고
    • Cutting edge: Antigen-independent CD8 T cell proliferation
    • Wong P, Pamer EG. Cutting edge: antigen-independent CD8 T cell proliferation. J Immunol 2001; 166:5864-8.
    • (2001) J Immunol , vol.166 , pp. 5864-5868
    • Wong, P.1    Pamer, E.G.2
  • 189
    • 0037398404 scopus 로고    scopus 로고
    • Feedback regulation of pathogen-specific T cell priming
    • Wong P, Pamer EG. Feedback regulation of pathogen-specific T cell priming. Immunity 2003; 18:499-511.
    • (2003) Immunity , vol.18 , pp. 499-511
    • Wong, P.1    Pamer, E.G.2
  • 190
    • 11144297289 scopus 로고    scopus 로고
    • Chemokines, Sphingosine-1-Phosphate, and Cell Migration in Secondary Lymphoid Organs
    • Cyster JG. Chemokines, Sphingosine-1-Phosphate, and Cell Migration in Secondary Lymphoid Organs. Annu Rev Immunol 2004.
    • (2004) Annu Rev Immunol
    • Cyster, J.G.1
  • 191
    • 0242417491 scopus 로고    scopus 로고
    • Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice
    • Badovinac VP, Hamilton SE, Harty JT. Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice. Immunity 2003; 18:463-74.
    • (2003) Immunity , vol.18 , pp. 463-474
    • Badovinac, V.P.1    Hamilton, S.E.2    Harty, J.T.3
  • 192
    • 0034680811 scopus 로고    scopus 로고
    • Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma
    • Badovinac VP, Tvinnereim AR, Harty JT. Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma. Science 2000; 290:1354-8.
    • (2000) Science , vol.290 , pp. 1354-1358
    • Badovinac, V.P.1    Tvinnereim, A.R.2    Harty, J.T.3
  • 193
    • 0036302172 scopus 로고    scopus 로고
    • Programmed contraction of CD8(+) T cells after infection
    • Badovinac VP, Porter BB, Harty JT. Programmed contraction of CD8(+) T cells after infection. Nat Immunol 2002; 3:619-26.
    • (2002) Nat Immunol , vol.3 , pp. 619-626
    • Badovinac, V.P.1    Porter, B.B.2    Harty, J.T.3
  • 194
    • 0033136321 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis
    • Algeciras-Schimnich A, Griffith TS, Lynch DH, Paya CV Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis. J Immunol 1999; 162:5205-11.
    • (1999) J Immunol , vol.162 , pp. 5205-5211
    • Algeciras-Schimnich, A.1    Griffith, T.S.2    Lynch, D.H.3    Paya, C.V.4
  • 195
    • 0842300364 scopus 로고    scopus 로고
    • Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort
    • Schmitz I, Weyd H, Krueger A, et al. Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort. J Immunol 2004; 172:2194-200.
    • (2004) J Immunol , vol.172 , pp. 2194-2200
    • Schmitz, I.1    Weyd, H.2    Krueger, A.3
  • 196
    • 0033956309 scopus 로고    scopus 로고
    • TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions
    • Nguyen LT, McKall-Faienza K, Zakarian A, et al. TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions. Eur J Immunol 2000; 30:683-8.
    • (2000) Eur J Immunol , vol.30 , pp. 683-688
    • Nguyen, L.T.1    McKall-Faienza, K.2    Zakarian, A.3
  • 197
    • 0342470585 scopus 로고    scopus 로고
    • Immune downregulation and peripheral deletion of CD8 T cells does not require TNF receptor-ligand interactions nor CD95 (Fas, APO-1)
    • Reich A, Korner H, Sedgwick JD, Pircher H. Immune downregulation and peripheral deletion of CD8 T cells does not require TNF receptor-ligand interactions nor CD95 (Fas, APO-1). Eur J Immunol 2000; 30:678-82.
    • (2000) Eur J Immunol , vol.30 , pp. 678-682
    • Reich, A.1    Korner, H.2    Sedgwick, J.D.3    Pircher, H.4
  • 198
    • 9144253961 scopus 로고    scopus 로고
    • The contraction phase of virus-specific CD8+ T cells is unaffected by a pan-caspase inhibitor
    • Nussbaum AK, Whitton JL. The contraction phase of virus-specific CD8+ T cells is unaffected by a pan-caspase inhibitor. J Immunol 2004; 173:6611-8.
    • (2004) J Immunol , vol.173 , pp. 6611-6618
    • Nussbaum, A.K.1    Whitton, J.L.2
  • 199
    • 1542327683 scopus 로고    scopus 로고
    • Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering
    • U S A
    • Sandalova E, Wei CH, Masucci MG, Levitsky V. Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering. Proc Natl Acad Sci U S A 2004; 101:3011-6.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 3011-3016
    • Sandalova, E.1    Wei, C.H.2    Masucci, M.G.3    Levitsky, V.4
  • 200
    • 0344198588 scopus 로고    scopus 로고
    • Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim
    • U S A
    • Pellegrini M, Belz G, Bouillet P, Strasser A. Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proc Natl Acad Sci U S A 2003; 100:14175-80.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 14175-14180
    • Pellegrini, M.1    Belz, G.2    Bouillet, P.3    Strasser, A.4
  • 201
    • 8644219870 scopus 로고    scopus 로고
    • Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice
    • Pellegrini M, Bouillet P, Robati M, et al. Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice. J Exp Med 2004; 200:1189-95.
    • (2004) J Exp Med , vol.200 , pp. 1189-1195
    • Pellegrini, M.1    Bouillet, P.2    Robati, M.3
  • 202
    • 18944403760 scopus 로고    scopus 로고
    • Dynamic regulation of IFN-gamma signaling in antigen-specific CD8+ T cells responding to infection
    • Haring JS, Corbin GA, Harty JT. Dynamic regulation of IFN-gamma signaling in antigen-specific CD8+ T cells responding to infection. J Immunol 2005; 174:6791-802.
    • (2005) J Immunol , vol.174 , pp. 6791-6802
    • Haring, J.S.1    Corbin, G.A.2    Harty, J.T.3
  • 203
    • 0034660503 scopus 로고    scopus 로고
    • Adaptive immunity and enhanced CD8+ T cell response to Listeria monocytogenes in the absence of perforin and IFN-gamma
    • Badovinac VP, Harty JT. Adaptive immunity and enhanced CD8+ T cell response to Listeria monocytogenes in the absence of perforin and IFN-gamma. J Immunol 2000; 164:6444-52.
    • (2000) J Immunol , vol.164 , pp. 6444-6452
    • Badovinac, V.P.1    Harty, J.T.2
  • 204
    • 4444253689 scopus 로고    scopus 로고
    • CD8+ T cell contraction is controlled by early inflammation
    • Badovinac VP, Porter BB, Harty JT. CD8+ T cell contraction is controlled by early inflammation. Nat Immunol 2004; 5:809-17.
    • (2004) Nat Immunol , vol.5 , pp. 809-817
    • Badovinac, V.P.1    Porter, B.B.2    Harty, J.T.3
  • 205
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech SM, Tan JT, Wherry EJ, et al. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 2003; 4:1191-8.
    • (2003) Nat Immunol , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3
  • 206
    • 2142756661 scopus 로고    scopus 로고
    • CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors
    • Madakamutil LT, Christen U, Lena CJ, et al. CD8alphaalpha-mediated
    • (2004) Science , vol.304 , pp. 590-593
    • Madakamutil, L.T.1    Christen, U.2    Lena, C.J.3
  • 207
    • 0035976604 scopus 로고    scopus 로고
    • T cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL
    • Leishman AJ, Naidenko OV, Attinger A, et al. T cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL. Science 2001; 294:1936-9.
    • (2001) Science , vol.294 , pp. 1936-1939
    • Leishman, A.J.1    Naidenko, O.V.2    Attinger, A.3
  • 208
    • 23444453484 scopus 로고    scopus 로고
    • Cutting edge: A single MHC class ia is sufficient for CD8 memory T cell differentiation
    • Williams MA, Bevan MJ. Cutting edge: a single MHC class ia is sufficient for CD8 memory T cell differentiation. J Immunol 2005; 175:2066-9.
    • (2005) J Immunol , vol.175 , pp. 2066-2069
    • Williams, M.A.1    Bevan, M.J.2
  • 209
    • 0032720640 scopus 로고    scopus 로고
    • Persistence of memory CD8 T cells in MHC class I-deficient mice
    • Murali-Krishna K, Lau LL, Sambhara S, et al. Persistence of memory CD8 T cells in MHC class I-deficient mice. Science 1999; 286:1377-81.
    • (1999) Science , vol.286 , pp. 1377-1381
    • Murali-Krishna, K.1    Lau, L.L.2    Sambhara, S.3
  • 210
    • 0034633683 scopus 로고    scopus 로고
    • IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice
    • U S A
    • Marks-Konczalik J, Dubois S, Losi JM, et al. IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice. Proc Natl Acad Sci U S A 2000; 97:11445-50.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 11445-11450
    • Marks-Konczalik, J.1    Dubois, S.2    Losi, J.M.3
  • 211
    • 0036467552 scopus 로고    scopus 로고
    • Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure
    • Yajima T, Nishimura H, Ishimitsu R, et al. Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure. J Immunol 2002; 168:1198-203.
    • (2002) J Immunol , vol.168 , pp. 1198-1203
    • Yajima, T.1    Nishimura, H.2    Ishimitsu, R.3
  • 212
    • 0037093844 scopus 로고    scopus 로고
    • Cutting edge: Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells
    • Schluns KS, Williams K, Ma A, Zheng XX, Lefrancois L. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol 2002; 168:4827-31.
    • (2002) J Immunol , vol.168 , pp. 4827-4831
    • Schluns, K.S.1    Williams, K.2    Ma, A.3    Zheng, X.X.4    Lefrancois, L.5
  • 213
    • 0037124341 scopus 로고    scopus 로고
    • Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
    • Becker TC, Wherry EJ, Boone D, et al. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 2002; 195:1541-8.
    • (2002) J Exp Med , vol.195 , pp. 1541-1548
    • Becker, T.C.1    Wherry, E.J.2    Boone, D.3
  • 214
    • 0038487052 scopus 로고    scopus 로고
    • Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
    • Seddon B, Tomlinson P, Zamoyska R. Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol 2003; 4:680-6.
    • (2003) Nat Immunol , vol.4 , pp. 680-686
    • Seddon, B.1    Tomlinson, P.2    Zamoyska, R.3
  • 215
    • 10244243681 scopus 로고    scopus 로고
    • Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis
    • Munitic I, Williams JA, Yang Y, et al. Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis. Blood 2004; 104:4165-72.
    • (2004) Blood , vol.104 , pp. 4165-4172
    • Munitic, I.1    Williams, J.A.2    Yang, Y.3
  • 216
    • 4143151485 scopus 로고    scopus 로고
    • IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: Impact on thymocyte development
    • Yu Q, Erman B, Park JH, Feigenbaum L, Singer A. IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development. J Exp Med 2004; 200:797-803.
    • (2004) J Exp Med , vol.200 , pp. 797-803
    • Yu, Q.1    Erman, B.2    Park, J.H.3    Feigenbaum, L.4    Singer, A.5
  • 217
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival
    • Park JH, Yu Q, Erman B, et al. Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 2004; 21:289-302.
    • (2004) Immunity , vol.21 , pp. 289-302
    • Park, J.H.1    Yu, Q.2    Erman, B.3
  • 218
    • 0037833701 scopus 로고    scopus 로고
    • Death and Baxes: Mechanisms of lymphotrophic cytokines
    • Khaled AR, Durum SK. Death and Baxes: mechanisms of lymphotrophic cytokines. Immunol Rev 2003; 193:48-57.
    • (2003) Immunol Rev , vol.193 , pp. 48-57
    • Khaled, A.R.1    Durum, S.K.2
  • 219
    • 0035159241 scopus 로고    scopus 로고
    • Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development
    • Wen R, Wang D, McKay C, et al. Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development. Mol Cell Biol 2001; 21:678-89.
    • (2001) Mol Cell Biol , vol.21 , pp. 678-689
    • Wen, R.1    Wang, D.2    McKay, C.3
  • 220
    • 0033120591 scopus 로고    scopus 로고
    • Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
    • Harada H, Becknell B, Wilm M, et al. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol Cell 1999; 3:413-22.
    • (1999) Mol Cell , vol.3 , pp. 413-422
    • Harada, H.1    Becknell, B.2    Wilm, M.3
  • 221
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 2000; 10:1201-4.
    • (2000) Curr Biol , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 222
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • Boise LH, Minn AJ, Noel PJ, et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995; 3:87-98.
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.H.1    Minn, A.J.2    Noel, P.J.3
  • 223
    • 0035319244 scopus 로고    scopus 로고
    • A point mutation in CD28 distinguishes proliferative signals from survival signals
    • Okkenhaug K, Wu L, Garza KM, et al. A point mutation in CD28 distinguishes proliferative signals from survival signals. Nat Immunol 2001; 2:325-32.
    • (2001) Nat Immunol , vol.2 , pp. 325-332
    • Okkenhaug, K.1    Wu, L.2    Garza, K.M.3
  • 224
    • 0038545370 scopus 로고    scopus 로고
    • CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes
    • Parry RV, Rumbley CA, Vandenberghe LH, June CH, Riley JL. CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes. J Immunol 2003; 171:166-74.
    • (2003) J Immunol , vol.171 , pp. 166-174
    • Parry, R.V.1    Rumbley, C.A.2    Vandenberghe, L.H.3    June, C.H.4    Riley, J.L.5
  • 225
    • 0035340150 scopus 로고    scopus 로고
    • Cutting edge: Distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL
    • Burr JS, Savage ND, Messah GE, et al. Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL. J Immunol 2001; 166:5331-5.
    • (2001) J Immunol , vol.166 , pp. 5331-5335
    • Burr, J.S.1    Savage, N.D.2    Messah, G.E.3
  • 226
    • 0027281691 scopus 로고
    • Differential T cell costimulatory requirements in CD28-deficient mice
    • Shahinian A, Pfeffer K, Lee KP, et al. Differential T cell costimulatory requirements in CD28-deficient mice. Science 1993; 261:609-12.
    • (1993) Science , vol.261 , pp. 609-612
    • Shahinian, A.1    Pfeffer, K.2    Lee, K.P.3
  • 227
    • 0036191093 scopus 로고    scopus 로고
    • CD28(-/-) mice show defects in cellular and humoral immunity but are able to control infection with murine gammaherpesvirus 68
    • Lee BJ, Reiter SK, Anderson M, Sarawar SR. CD28(-/-) mice show defects in cellular and humoral immunity but are able to control infection with murine gammaherpesvirus 68. J Virol 2002; 76:3049-53.
    • (2002) J Virol , vol.76 , pp. 3049-3053
    • Lee, B.J.1    Reiter, S.K.2    Anderson, M.3    Sarawar, S.R.4
  • 228
    • 0033988482 scopus 로고    scopus 로고
    • B7 costimulation is critical for antibody class switching and CD8 (+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus
    • McAdam AJ, Farkash EA, Gewurz BE, Sharpe AH. B7 costimulation is critical for antibody class switching and CD8 (+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus. J Virol 2000; 74:203-8.
    • (2000) J Virol , vol.74 , pp. 203-208
    • McAdam, A.J.1    Farkash, E.A.2    Gewurz, B.E.3    Sharpe, A.H.4
  • 229
    • 0035889949 scopus 로고    scopus 로고
    • Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory
    • Suresh M, Whitmire JK, Harrington LE, et al. Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory. J Immunol 2001; 167:5565-73.
    • (2001) J Immunol , vol.167 , pp. 5565-5573
    • Suresh, M.1    Whitmire, J.K.2    Harrington, L.E.3
  • 230
    • 0035889910 scopus 로고    scopus 로고
    • Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes
    • Mittrucker HW, Kursar M, Kohler A, Hurwitz R, Kaufmann SH. Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes. J Immunol 2001; 167:5620-7.
    • (2001) J Immunol , vol.167 , pp. 5620-5627
    • Mittrucker, H.W.1    Kursar, M.2    Kohler, A.3    Hurwitz, R.4    Kaufmann, S.H.5
  • 231
    • 0242611000 scopus 로고    scopus 로고
    • CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool
    • Hendriks J, Xiao Y, Borst J. CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool. J Exp Med 2003; 198:1369-80.
    • (2003) J Exp Med , vol.198 , pp. 1369-1380
    • Hendriks, J.1    Xiao, Y.2    Borst, J.3
  • 232
    • 0034812971 scopus 로고    scopus 로고
    • OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
    • Rogers PR, Song J, Gramaglia I, Killeen N, Croft M. OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity 2001; 15:445-55.
    • (2001) Immunity , vol.15 , pp. 445-455
    • Rogers, P.R.1    Song, J.2    Gramaglia, I.3    Killeen, N.4    Croft, M.5
  • 233
    • 1142263117 scopus 로고    scopus 로고
    • The costimulation-regulated duration of PKB activation controls T cell longevity
    • Song J, Salek-Ardakani S, Rogers PR, et al. The costimulation-regulated duration of PKB activation controls T cell longevity. Nat Immunol 2004; 5:150-8.
    • (2004) Nat Immunol , vol.5 , pp. 150-158
    • Song, J.1    Salek-Ardakani, S.2    Rogers, P.R.3
  • 234
    • 0141609073 scopus 로고    scopus 로고
    • Co-stimulatory members of the TNFR family: Keys to effective T-cell immunity?
    • Croft M. Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? Nat Rev Immunol 2003; 3:609-20.
    • (2003) Nat Rev Immunol , vol.3 , pp. 609-620
    • Croft, M.1
  • 235
    • 0038066310 scopus 로고    scopus 로고
    • CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells
    • Kim MY, Gaspal FM, Wiggett HE, et al. CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells. Immunity 2003; 18:643-54.
    • (2003) Immunity , vol.18 , pp. 643-654
    • Kim, M.Y.1    Gaspal, F.M.2    Wiggett, H.E.3
  • 236
    • 0033427047 scopus 로고    scopus 로고
    • OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection
    • Kopf M, Ruedl C, Schmitz N, et al. OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection. Immunity 1999; 11:699-708.
    • (1999) Immunity , vol.11 , pp. 699-708
    • Kopf, M.1    Ruedl, C.2    Schmitz, N.3
  • 237
    • 0034665502 scopus 로고    scopus 로고
    • The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion
    • Gramaglia I, Jember A, Pippig SD, et al. The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion. J Immunol 2000; 165:3043-50.
    • (2000) J Immunol , vol.165 , pp. 3043-3050
    • Gramaglia, I.1    Jember, A.2    Pippig, S.D.3
  • 238
    • 0036838689 scopus 로고    scopus 로고
    • 4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1
    • Lee HW, Park SJ, Choi BK, et al. 4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1. J Immunol 2002; 169:4882-8.
    • (2002) J Immunol , vol.169 , pp. 4882-4888
    • Lee, H.W.1    Park, S.J.2    Choi, B.K.3
  • 239
    • 0036800027 scopus 로고    scopus 로고
    • 4-1BB co-stimulation enhances human CD8(+) T cell priming by augmenting the proliferation and survival of effector CD8(+) T cells
    • Laderach D, Movassagh M, Johnson A, Mittler RS, Galy A. 4-1BB co-stimulation enhances human CD8(+) T cell priming by augmenting the proliferation and survival of effector CD8(+) T cells. Int Immunol 2002; 14:1155-67.
    • (2002) Int Immunol , vol.14 , pp. 1155-1167
    • Laderach, D.1    Movassagh, M.2    Johnson, A.3    Mittler, R.S.4    Galy, A.5
  • 240
    • 0842320993 scopus 로고    scopus 로고
    • Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses
    • U S A
    • Bukczynski J, Wen T, Ellefsen K, Gauldie J, Watts TH. Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. Proc Natl Acad Sci U S A 2004; 101:1291-6.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 1291-1296
    • Bukczynski, J.1    Wen, T.2    Ellefsen, K.3    Gauldie, J.4    Watts, T.H.5
  • 241
    • 0032754036 scopus 로고    scopus 로고
    • Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus
    • DeBenedette MA, Wen T, Bachmann MF, et al. Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J Immunol 1999; 163:4833-41.
    • (1999) J Immunol , vol.163 , pp. 4833-4841
    • DeBenedette, M.A.1    Wen, T.2    Bachmann, M.F.3
  • 242
    • 0032711836 scopus 로고    scopus 로고
    • 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses
    • Tan JT, Whitmire JK, Ahmed R, Pearson TC, Larsen CP. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. J Immunol 1999; 163:4859-68.
    • (1999) J Immunol , vol.163 , pp. 4859-4868
    • Tan, J.T.1    Whitmire, J.K.2    Ahmed, R.3    Pearson, T.C.4    Larsen, C.P.5
  • 243
    • 0036604470 scopus 로고    scopus 로고
    • Immune responses in 4-1BB (CD137)-deficient mice
    • Kwon BS, Hurtado JC, Lee ZH, et al. Immune responses in 4-1BB (CD137)-deficient mice. J Immunol 2002; 168:5483-90.
    • (2002) J Immunol , vol.168 , pp. 5483-5490
    • Kwon, B.S.1    Hurtado, J.C.2    Lee, Z.H.3
  • 244
    • 0032813589 scopus 로고    scopus 로고
    • Evidence that human CD8+CD45RA+CD27- cells are induced by antigen and evolve through extensive rounds of division
    • Hamann D, Kostense S, Wolthers KC, et al. Evidence that human CD8+CD45RA+CD27- cells are induced by antigen and evolve through extensive rounds of division. Int Immunol 1999; 11:1027-33.
    • (1999) Int Immunol , vol.11 , pp. 1027-1033
    • Hamann, D.1    Kostense, S.2    Wolthers, K.C.3
  • 245
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD8 T cell subsets
    • Wherry EJ, Teichgraber V, Becker TC, et al. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol 2003; 4:225-34.
    • (2003) Nat Immunol , vol.4 , pp. 225-234
    • Wherry, E.J.1    Teichgraber, V.2    Becker, T.C.3
  • 246
    • 0034329745 scopus 로고    scopus 로고
    • CD27 is required for generation and long-term maintenance of T cell immunity
    • Hendriks J, Gravestein LA, Tesselaar K, et al. CD27 is required for generation and long-term maintenance of T cell immunity. Nat Immunol 2000; 1:433-40.
    • (2000) Nat Immunol , vol.1 , pp. 433-440
    • Hendriks, J.1    Gravestein, L.A.2    Tesselaar, K.3
  • 247
    • 18944372860 scopus 로고    scopus 로고
    • The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes
    • Zhang N, He YW. The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes. J Immunol 2005; 174:6967-73.
    • (2005) J Immunol , vol.174 , pp. 6967-6973
    • Zhang, N.1    He, Y.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.