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Volumn 193, Issue , 2003, Pages 48-57

Death and Baxes: Mechanisms of lymphotrophic cytokines

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; INTERLEUKIN 3; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; PROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; STAT PROTEIN; UNCLASSIFIED DRUG;

EID: 0037833701     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2003.00050.x     Document Type: Review
Times cited : (57)

References (92)
  • 1
    • 0027209141 scopus 로고
    • Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody
    • Grabstein KH, et al. Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody. J Exp Med 1993;178:257-264.
    • (1993) J Exp Med , vol.178 , pp. 257-264
    • Grabstein, K.H.1
  • 3
    • 0030877757 scopus 로고    scopus 로고
    • Defective T-cell receptor gamma gene rearrangement in interleukin-7 receptor knockout mice
    • Candelas S, Peschon JJ, Muegge K, Durum SK. Defective T-cell receptor gamma gene rearrangement in interleukin-7 receptor knockout mice. Immunol Lett 1997;57:9-14.
    • (1997) Immunol Lett , vol.57 , pp. 9-14
    • Candelas, S.1    Peschon, J.J.2    Muegge, K.3    Durum, S.K.4
  • 4
  • 5
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • von-Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SE, Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 1995;181:1519-1526.
    • (1995) J Exp Med , vol.181 , pp. 1519-1526
    • Von-Freeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3    McNeil, T.4    Burdach, S.E.5    Murray, R.6
  • 7
    • 0027988545 scopus 로고
    • Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
    • Peschon JJ, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 1994; 180: 1955-1960.
    • (1994) J Exp Med , vol.180 , pp. 1955-1960
    • Peschon, J.J.1
  • 8
    • 0030589289 scopus 로고    scopus 로고
    • Impaired survival and proliferation in IL-7 receptor-deficient peripheral T cells
    • Maraskovsky E, et al. Impaired survival and proliferation in IL-7 receptor-deficient peripheral T cells. J Immunol 1996;157:5315-5323.
    • (1996) J Immunol , vol.157 , pp. 5315-5323
    • Maraskovsky, E.1
  • 9
    • 0343812092 scopus 로고    scopus 로고
    • IL-7 receptor and VDJ recombination: Trophic versus mechanistic actions
    • Candeias S, Muegge K, Durum SK. IL-7 receptor and VDJ recombination: trophic versus mechanistic actions. Immunity 1997;6:501-508.
    • (1997) Immunity , vol.6 , pp. 501-508
    • Candeias, S.1    Muegge, K.2    Durum, S.K.3
  • 10
    • 0032526586 scopus 로고    scopus 로고
    • The trophic action of IL-7 on pro-T cells: Inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways
    • Kim K, Lee CK, Sayers TJ, Muegge K, Durum SK. The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways. J Immunol 1998;160:5735-5741.
    • (1998) J Immunol , vol.160 , pp. 5735-5741
    • Kim, K.1    Lee, C.K.2    Sayers, T.J.3    Muegge, K.4    Durum, S.K.5
  • 11
    • 0036831818 scopus 로고    scopus 로고
    • Lymphocide: Cytokines and the control of lymphoid homeostasis
    • Khaled AR, Durum SK. Lymphocide: cytokines and the control of lymphoid homeostasis. Nat Rev Immunol 2002;2:817-830.
    • (2002) Nat Rev Immunol , vol.2 , pp. 817-830
    • Khaled, A.R.1    Durum, S.K.2
  • 12
    • 0036771728 scopus 로고    scopus 로고
    • The role of cytokines in lymphocyte homeostasis
    • Khaled AR, Durum SK. The role of cytokines in lymphocyte homeostasis. Biotechniques 2002;Suppl:40-45.
    • (2002) Biotechniques , Issue.SUPPL. , pp. 40-45
    • Khaled, A.R.1    Durum, S.K.2
  • 13
    • 0030873556 scopus 로고    scopus 로고
    • Differential requirements for survival and proliferation of CD8 naïve or memory T cells
    • Tanchot C, Lemonnier FA, Perarnau B, Freitas AA, Rocha B. Differential requirements for survival and proliferation of CD8 naïve or memory T cells. Science 1997;276:2057-2062.
    • (1997) Science , vol.276 , pp. 2057-2062
    • Tanchot, C.1    Lemonnier, F.A.2    Perarnau, B.3    Freitas, A.A.4    Rocha, B.5
  • 16
    • 0034698931 scopus 로고    scopus 로고
    • Naïve T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
    • Goldrath AW, Bogatzki LY, Bevan MJ. Naïve T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J Exp Med 2000;192:557-564.
    • (2000) J Exp Med , vol.192 , pp. 557-564
    • Goldrath, A.W.1    Bogatzki, L.Y.2    Bevan, M.J.3
  • 17
    • 0033180491 scopus 로고    scopus 로고
    • The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
    • Ernst B, Lee DS, Chang JM, Sprent J, Surh CD. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 1999;11:173-181.
    • (1999) Immunity , vol.11 , pp. 173-181
    • Ernst, B.1    Lee, D.S.2    Chang, J.M.3    Sprent, J.4    Surh, C.D.5
  • 18
    • 0033539516 scopus 로고    scopus 로고
    • Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands
    • Kieper WC, Jameson SC. Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands. Proc Natl Acad Sci USA 1999;96:13306-13311.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13306-13311
    • Kieper, W.C.1    Jameson, S.C.2
  • 20
    • 0035902513 scopus 로고    scopus 로고
    • IL-7 is critical for homeostatic proliferation and survival of naïve T cells
    • Tan JT, et al. IL-7 is critical for homeostatic proliferation and survival of naïve T cells. Proc Natl Acad Sci USA 2001;98:8732-8737.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8732-8737
    • Tan, J.T.1
  • 21
    • 0037124328 scopus 로고    scopus 로고
    • Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8(+) T Cells
    • Kieper WC, et al. Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8(+) T Cells. J Exp Med 2002;195:1533-1539.
    • (2002) J Exp Med , vol.195 , pp. 1533-1539
    • Kieper, W.C.1
  • 23
    • 0027972541 scopus 로고
    • The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen
    • Mullbacher A. The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen. J Exp Med 1994;179:317-321.
    • (1994) J Exp Med , vol.179 , pp. 317-321
    • Mullbacher, A.1
  • 24
    • 5844320555 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Nat Immun 2000;1:107-111.
    • (2000) Nat Immun , vol.1 , pp. 107-111
    • Marrack, P.1
  • 25
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce JP, et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998;9:669-676.
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1
  • 26
    • 0037080022 scopus 로고    scopus 로고
    • + T cells deficient in the IL-15 receptor alpha-chain
    • + T cells deficient in the IL-15 receptor alpha-chain. J Immunol 2002;168:705-712.
    • (2002) J Immunol , vol.168 , pp. 705-712
    • Wu, T.S.1
  • 27
    • 0034610970 scopus 로고    scopus 로고
    • Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
    • Kennedy MK, et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000;191:771-780.
    • (2000) J Exp Med , vol.191 , pp. 771-780
    • Kennedy, M.K.1
  • 28
    • 0034610983 scopus 로고    scopus 로고
    • The pleiotropic functions of interleukin 15: Not so interleukin 2-like after all
    • Ma A, Boone DL, Lodolce JP. The pleiotropic functions of interleukin 15: not so interleukin 2-like after all. J Exp Med 2000;191:753-756.
    • (2000) J Exp Med , vol.191 , pp. 753-756
    • Ma, A.1    Boone, D.L.2    Lodolce, J.P.3
  • 29
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo
    • Schluns KS, Kieper WC, Jameson SC, Lefrancois L. Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. Nat Immun 2000;1:426-432.
    • (2000) Nat Immun , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 30
    • 0037124366 scopus 로고    scopus 로고
    • Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8(+) cells but are not required for memory phenotype CD4(+) cells
    • Tan JT, Ernst B, Kieper WC, LeRoy E, Sprent J, Surh CD. Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8(+) cells but are not required for memory phenotype CD4(+) cells. J Exp Med 2002;195:1523-1532.
    • (2002) J Exp Med , vol.195 , pp. 1523-1532
    • Tan, J.T.1    Ernst, B.2    Kieper, W.C.3    LeRoy, E.4    Sprent, J.5    Surh, C.D.6
  • 31
    • 0028840706 scopus 로고
    • Defective lymphoid development in mice lacking Jak3
    • Nosaka T, et al. Defective lymphoid development in mice lacking Jak3. Science 1995;270:800-802.
    • (1995) Science , vol.270 , pp. 800-802
    • Nosaka, T.1
  • 32
    • 0029550822 scopus 로고
    • Developmental defects of lymphoid cells in Jak3 kinase-deficient mice
    • Park SY, et al. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity 1995;3:771-782.
    • (1995) Immunity , vol.3 , pp. 771-782
    • Park, S.Y.1
  • 33
    • 0033952813 scopus 로고    scopus 로고
    • Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c)-dependent signaling: Comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice
    • Suzuki K, Nakajima H, Saito Y, Saito T, Leonard WJ, Iwamoto I. Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c)-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice. Int Immunol 2000;12:123-132.
    • (2000) Int Immunol , vol.12 , pp. 123-132
    • Suzuki, K.1    Nakajima, H.2    Saito, Y.3    Saito, T.4    Leonard, W.J.5    Iwamoto, I.6
  • 34
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002. New surprises in the Jak/STAT pathway
    • O'Shea JJ, Gadina M, Schreiber RD. Cytokine signaling in 2002. New surprises in the Jak/STAT pathway. Cell 2002;109:S121-S131.
    • (2002) Cell , vol.109
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 35
    • 0034792532 scopus 로고    scopus 로고
    • Constitutive and interleukin-7- and interleukin-15-stimulated DNA binding of STAT and novel factors in cutaneous T cell lymphoma cells
    • Qin JZ, Kamarashev J, Zhang CL, Dummer R, Burg G, Dobbeling U. Constitutive and interleukin-7- and interleukin-15-stimulated DNA binding of STAT and novel factors in cutaneous T cell lymphoma cells. J Invest Dermatol 2001;117:583-589.
    • (2001) J Invest Dermatol , vol.117 , pp. 583-589
    • Qin, J.Z.1    Kamarashev, J.2    Zhang, C.L.3    Dummer, R.4    Burg, G.5    Dobbeling, U.6
  • 36
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
    • Lin JX, et al. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 1995;2:331-339.
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.X.1
  • 37
    • 0028874974 scopus 로고
    • Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells
    • Foxwell BM, Beadling C, Guschin D, Kerr I, Cantrell D. Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells. Eur J Immunol 1995;25:3041-3046.
    • (1995) Eur J Immunol , vol.25 , pp. 3041-3046
    • Foxwell, B.M.1    Beadling, C.2    Guschin, D.3    Kerr, I.4    Cantrell, D.5
  • 38
    • 0029785520 scopus 로고    scopus 로고
    • Interleukin-7 signaling in human B cell precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STATS mediated via the interleukin-7 receptor alpha chain
    • van dP, Smiers F, Pouwels K, Hoefsloot LH, Lowenberg B, Touw IP. Interleukin-7 signaling in human B cell precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STATS mediated via the interleukin-7 receptor alpha chain. Leukemia 1996;10:1317-1325.
    • (1996) Leukemia , vol.10 , pp. 1317-1325
    • Van, D.P.1    Smiers, F.2    Pouwels, K.3    Hoefsloot, L.H.4    Lowenberg, B.5    Touw, I.P.6
  • 39
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev 1999;13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 40
    • 0034635264 scopus 로고    scopus 로고
    • Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
    • Sasaki T, et al. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science 2000;287:1040-1046.
    • (2000) Science , vol.287 , pp. 1040-1046
    • Sasaki, T.1
  • 41
    • 0028048445 scopus 로고
    • Activation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor is dependent on protein tyrosine kinase activity
    • Dadi H, Ke S, Roifman CM. Activation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor is dependent on protein tyrosine kinase activity. Blood 1994;84:1579-1586.
    • (1994) Blood , vol.84 , pp. 1579-1586
    • Dadi, H.1    Ke, S.2    Roifman, C.M.3
  • 42
    • 0033136288 scopus 로고    scopus 로고
    • Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors
    • Pallard C, Stegmann AP, van Kleffens T, Smart F, Venkitaraman A, Spits H. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 1999;10:525-535.
    • (1999) Immunity , vol.10 , pp. 525-535
    • Pallard, C.1    Stegmann, A.P.2    Van Kleffens, T.3    Smart, F.4    Venkitaraman, A.5    Spits, H.6
  • 43
    • 0036849781 scopus 로고    scopus 로고
    • Bax deficiency partially corrects IL-7 receptor alpha deficiency
    • Khaled AR, et al. Bax deficiency partially corrects IL-7 receptor alpha deficiency. Immunity 2002;17:561-573.
    • (2002) Immunity , vol.17 , pp. 561-573
    • Khaled, A.R.1
  • 44
    • 0037080219 scopus 로고    scopus 로고
    • IL-2 and related cytokines can promote T cell survival by activating AKT
    • Kelly E, Won A, Refaeh Y, Van Parijs L. IL-2 and related cytokines can promote T cell survival by activating AKT. J Immunol 2002;168:597-603.
    • (2002) J Immunol , vol.168 , pp. 597-603
    • Kelly, E.1    Won, A.2    Refaeh, Y.3    Van Parijs, L.4
  • 45
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
    • Brunet A, et al. Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor. Cell 1999;96:857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1
  • 46
    • 0037094096 scopus 로고    scopus 로고
    • The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
    • Stahl M, et al. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 2002;168:5024-5031.
    • (2002) J Immunol , vol.168 , pp. 5024-5031
    • Stahl, M.1
  • 47
    • 0030255521 scopus 로고    scopus 로고
    • Lessons from Bcl-2 transgenic mice for immunology, cancer biology and cell death research
    • Strasser A, et al. Lessons from Bcl-2 transgenic mice for immunology, cancer biology and cell death research. Behring Inst Mitt 1996;101-117.
    • (1996) Behring Inst Mitt , pp. 101-117
    • Strasser, A.1
  • 49
    • 0025751550 scopus 로고
    • bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ. bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 1991;67:879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 50
    • 0025786164 scopus 로고
    • bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser A, Harris AW, Cory S. bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 1991;67:889-899.
    • (1991) Cell , vol.67 , pp. 889-899
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 51
    • 0033593038 scopus 로고    scopus 로고
    • Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival
    • Ogilvy S, Metcalf D, Print CG, Bath ML, Harris AW, Adams JM. Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival. Proc Natl Acad Sci USA 1999;96:14943-14948.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14943-14948
    • Ogilvy, S.1    Metcalf, D.2    Print, C.G.3    Bath, M.L.4    Harris, A.W.5    Adams, J.M.6
  • 52
    • 0027248447 scopus 로고
    • bcl-2 proto-oncogene expression during human T cell development. Evidence for biphasic regulation
    • Gratiot DJ, Ding L, Turka LA, Nunez G. bcl-2 proto-oncogene expression during human T cell development. Evidence for biphasic regulation. J Immunol 1993;151:83-91.
    • (1993) J Immunol , vol.151 , pp. 83-91
    • Gratiot, D.J.1    Ding, L.2    Turka, L.A.3    Nunez, G.4
  • 53
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 1993;75:229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 55
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi K, Kondo M, von Freeden-Jeffry U, Murray R, Weissman IL. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 1997;89:1033-1041.
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    Von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 56
    • 0033556320 scopus 로고    scopus 로고
    • Role of Bcl-2 in alpha beta T cell development in mice deficient in the common cytokine receptor gamma-chain: The requirement for Bcl-2 differs depending on the TCR/MHC affinity
    • Nakajima H, Leonard WJ. Role of Bcl-2 in alpha beta T cell development in mice deficient in the common cytokine receptor gamma-chain: the requirement for Bcl-2 differs depending on the TCR/MHC affinity. J Immunol 1999;162:782-790.
    • (1999) J Immunol , vol.162 , pp. 782-790
    • Nakajima, H.1    Leonard, W.J.2
  • 57
    • 0032441260 scopus 로고    scopus 로고
    • Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: Role of receptor-associated chains and locus accessibility
    • Durum SK, et al. Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility. J Exp Med 1998;188:2233-2241.
    • (1998) J Exp Med , vol.188 , pp. 2233-2241
    • Durum, S.K.1
  • 58
    • 0031715301 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 does not rescue impaired B lymphopoiesis in IL-7 receptor-deficient mice but can enhance survival of mature B cells
    • Maraskovsky E, Peschon JJ, McKenna H, Teepe M, Strasser A. Overexpression of Bcl-2 does not rescue impaired B lymphopoiesis in IL-7 receptor-deficient mice but can enhance survival of mature B cells. Int Immunol 1998;10:1367-1375.
    • (1998) Int Immunol , vol.10 , pp. 1367-1375
    • Maraskovsky, E.1    Peschon, J.J.2    McKenna, H.3    Teepe, M.4    Strasser, A.5
  • 59
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001;15:1481-1486.
    • (2001) Genes Dev , vol.15 , pp. 1481-1486
    • Zong, W.X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 60
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998;94:491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 61
    • 0033534446 scopus 로고    scopus 로고
    • Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death
    • Gross A, et al. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem 1999;274:1156-1163.
    • (1999) J Biol Chem , vol.274 , pp. 1156-1163
    • Gross, A.1
  • 62
    • 0033607006 scopus 로고    scopus 로고
    • Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
    • Yin XM, et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 1999;400:886-891.
    • (1999) Nature , vol.400 , pp. 886-891
    • Yin, X.M.1
  • 63
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR, Cantley LC. PI3K: downstream AKTion blocks apoptosis. Cell 1997;88:435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 64
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997;91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1
  • 65
    • 0033635235 scopus 로고    scopus 로고
    • 14-3-3 Proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
    • Datta SR, et al. 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation. Mol Cell 2000;6:41-51.
    • (2000) Mol Cell , vol.6 , pp. 41-51
    • Datta, S.R.1
  • 66
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del-Peso L, Gonzalez GM, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997;278:687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del-Peso, L.1    Gonzalez, G.M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 67
    • 0033143385 scopus 로고    scopus 로고
    • How BAD phosphorylation is good for survival
    • Downward J. How BAD phosphorylation is good for survival. Nat Cell Biol 1999;1:E33-E35.
    • (1999) Nat Cell Biol , vol.1
    • Downward, J.1
  • 68
    • 0032518787 scopus 로고    scopus 로고
    • Bim: A novel member of the Bcl-2 family that promotes apoptosis
    • O'Connor L, et al. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J 1998;17:384-395.
    • (1998) EMBO J , vol.17 , pp. 384-395
    • O'Connor, L.1
  • 69
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • Puthalakath H, Huang DC, O'Reilly LA, King SM, Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 1999;3:287-296.
    • (1999) Mol Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.2    O'Reilly, L.A.3    King, S.M.4    Strasser, A.5
  • 70
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 2000;10:1201-1204.
    • (2000) Curr Biol , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 71
    • 0035514046 scopus 로고    scopus 로고
    • Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim
    • Bouillet P, Cory S, Zhang LC, Strasser A, Adams JM. Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim. Dev Cell 2001;1:645-653.
    • (2001) Dev Cell , vol.1 , pp. 645-653
    • Bouillet, P.1    Cory, S.2    Zhang, L.C.3    Strasser, A.4    Adams, J.M.5
  • 72
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999;286:1735-1738.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1
  • 73
    • 0033535347 scopus 로고    scopus 로고
    • Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis
    • Griffiths GJ, et al. Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis. J Cell Biol 1999;144:903-914.
    • (1999) J Cell Biol , vol.144 , pp. 903-914
    • Griffiths, G.J.1
  • 74
    • 0035891057 scopus 로고    scopus 로고
    • Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the proapoptotic protein Bak
    • Griffiths GJ, et al. Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the proapoptotic protein Bak. Oncogene 2001;20:7668-7676.
    • (2001) Oncogene , vol.20 , pp. 7668-7676
    • Griffiths, G.J.1
  • 75
    • 0034508217 scopus 로고    scopus 로고
    • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal devdopment of multiple tissues
    • Lindsten T, et al. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal devdopment of multiple tissues. Mol Cell 2000;6:1389-1399.
    • (2000) Mol Cell , vol.6 , pp. 1389-1399
    • Lindsten, T.1
  • 76
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 77
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001;295:727-730.
    • (2001) Science , vol.295 , pp. 727-730
    • Wei, M.C.1
  • 79
    • 0033406781 scopus 로고    scopus 로고
    • Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH
    • Khaled AR, Kim K, Hofmeister R, Muegge K, Durum SK. Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH. Proc Natl Acad Sci USA 1999;96:14476-14481.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14476-14481
    • Khaled, A.R.1    Kim, K.2    Hofmeister, R.3    Muegge, K.4    Durum, S.K.5
  • 80
    • 0035618703 scopus 로고    scopus 로고
    • From cytosol to mitochondria: The Bax translocation story
    • Khaled AR, Durum S. From cytosol to mitochondria: the Bax translocation story. J Biochem Mol Biol 2001;34:391-394.
    • (2001) J Biochem Mol Biol , vol.34 , pp. 391-394
    • Khaled, A.R.1    Durum, S.2
  • 81
    • 0031007644 scopus 로고    scopus 로고
    • Nonionic detergents induce dimerization among members of the Bcl-2 family
    • Hsu YT, Youle RJ. Nonionic detergents induce dimerization among members of the Bcl-2 family. J Biol Chem 1997;272:13829-13834.
    • (1997) J Biol Chem , vol.272 , pp. 13829-13834
    • Hsu, Y.T.1    Youle, R.J.2
  • 82
    • 0035159241 scopus 로고    scopus 로고
    • Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development
    • Wen R, et al. Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development. Mol Cell Biol 2001;21:678-689.
    • (2001) Mol Cell Biol , vol.21 , pp. 678-689
    • Wen, R.1
  • 83
    • 0022319450 scopus 로고
    • The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells
    • Dexter TM, Heyworth CM, Whetton AD. The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells. Ciba Found Symp 1985;116:129-147.
    • (1985) Ciba Found Symp , vol.116 , pp. 129-147
    • Dexter, T.M.1    Heyworth, C.M.2    Whetton, A.D.3
  • 84
    • 0031054903 scopus 로고    scopus 로고
    • Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest
    • Garland JM, Halestrap A. Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest. J Biol Chem 1997;272:4680-4688.
    • (1997) J Biol Chem , vol.272 , pp. 4680-4688
    • Garland, J.M.1    Halestrap, A.2
  • 85
    • 0035853833 scopus 로고    scopus 로고
    • Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology
    • Plas DR, Talapatra S, Edinger AL, Rathmell JC, Thompson CB. Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology. J Biol Chem 2001;276:12041-12048.
    • (2001) J Biol Chem , vol.276 , pp. 12041-12048
    • Plas, D.R.1    Talapatra, S.2    Edinger, A.L.3    Rathmell, J.C.4    Thompson, C.B.5
  • 86
  • 87
    • 0033776271 scopus 로고    scopus 로고
    • Changes in intramitochondrial and cytosolic pH: Early events that modulate caspase activation during apoptosis
    • Matsuyama S, Llopis J, Deveraux QL, Tsien RY, Reed JC. Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis. Nat Cell Biol 2000;2:318-325.
    • (2000) Nat Cell Biol , vol.2 , pp. 318-325
    • Matsuyama, S.1    Llopis, J.2    Deveraux, Q.L.3    Tsien, R.Y.4    Reed, J.C.5
  • 89
    • 0034780077 scopus 로고    scopus 로고
    • Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization
    • Khaled AR, et al. Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization. Mol Cell Biol 2001;21:7545-7557.
    • (2001) Mol Cell Biol , vol.21 , pp. 7545-7557
    • Khaled, A.R.1
  • 90
    • 0033575236 scopus 로고    scopus 로고
    • + exchanger isoform-1
    • + exchanger isoform-1. J Biol Chem 1999;274:20206-20214.
    • (1999) J Biol Chem , vol.274 , pp. 20206-20214
    • Takahashi, E.1
  • 91
    • 0035794204 scopus 로고    scopus 로고
    • Interleukin-3 withdrawal induces an early increase in mitochondrial membrane potential unrelated to the Bcl-2 family. Roles of intracellular pH, ADP transport, and F(0)F(1)-ATPase
    • Khaled AR., eynolds DA, Young HA, Thompson CB, Muegge K,Durum SK. Interleukin-3 withdrawal induces an early increase in mitochondrial membrane potential unrelated to the Bcl-2 family. Roles of intracellular pH, ADP transport, and F(0)F(1)-ATPase. J Biol Chem 2001;276:6453-6462.
    • (2001) J Biol Chem , vol.276 , pp. 6453-6462
    • Khaled, A.R.1    Reynolds, D.A.2    Young, H.A.3    Thompson, C.B.4    Muegge, K.5    Durum, S.K.6
  • 92
    • 0034956656 scopus 로고    scopus 로고
    • Mouse models for mitochondrial disease
    • Wallace DC. Mouse models for mitochondrial disease. Am J Med Genet 2001;106:71-93.
    • (2001) Am J Med Genet , vol.106 , pp. 71-93
    • Wallace, D.C.1


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