DR3 regulates negative selection during thymocyte development

Molecular and Cellular Biology

Volumn 21, Issue 10, 2001, Pages 3451-3461

  Wang, E C Y ^a   Thern, A ^a   Denzel, A ^a   Kitson, J ^a   Farrow, S N ^a   Owen, M J ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; GENE; GENE EXPRESSION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, KNOCKOUT; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 25; RECOMBINATION, GENETIC; T-LYMPHOCYTES;

ANIMALIA;

EID: 0035027854     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.10.3451-3461.2001     Document Type: Article

References (56)

1. Superantigens and tolerance
2. Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice
3. Modulation of life and death by the TNF receptor superfamily
4. Crystal structure of the soluble human 55 Kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
5. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas (Apo-1/CD95)
6. A novel protein that interacts with the death domain of Fas/Apo1 contains a sequence motif related to the death domain
7. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
8. Structure and expression of murine CD30 and its role in cytokine production
9. CD30 overexpression enhances negative selection in the thymus and mediates programmed cell death via a Bcl-2 sensitive pathway
10. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis
11. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
12. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
13. The cell-death machine
14. Caspase enzyme activity is not essential for apoptosis during thymocyte development
15. RAIDD is a new "death" adaptor molecule
16. Duplication of the DR3 gene on human chromosome 1p36 and its deletion in human neuroblastoma
17. ICE family proteases: Mediators of all apoptotic cell death?
18. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
19. The regulation of transcription by phosphorylation
20. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
21. Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor
22. + thymocytes
23. Several different cell surface molecules control negative selection of medullary thymocytes
24. A death domain-containing receptor that mediates apoptosis
25. A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development: Genetic evidence of synergism with lymphotoxin β
26. Distinct roles in lymphoid organogenesis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice
27. ICE-like proteases in apoptosis
28. Normal sequence of phenotypic transitions in one cohort of 5-bromo-2′-deoxyuridine-pulse labeled thymocytes
29. Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-κB
30. Identification of a ligand for the death-domain-containing receptor Apo3
31. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95(Fas/APO-1) death-inducing signaling complex
32. Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor
33. FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumor suppressor gene
34. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
35. TNF-related ligands and their receptors
36. Structural basis for self-association and receptor recognition of human TRAF2
37. Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor
38. Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3
39. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
40. TWEAK can induce cell death via endogenous TNF and TNF receptor 1
41. T cell life and death signalling via TNF-receptor family members
42. LARD, a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing
43. Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
44. The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation and death
45. Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene
46. + thymocytes
47. Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoetic and non-hematopoietic cells
48. A novel domain within the 55 kd TNF receptor signals cell death
49. Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells
50. A role for FADD in T cell activation and development
51. Genomic structure, expression and chromosome mapping of the murine homologue for the WSL-1 (DR3, Apo3, TRAMP, LARD, TR3, TNFRSF12) gene
52. Apoptosis mediated by the TNF-related cytokine and receptor families
53. A new death receptor 3 isoform: Expression in human lymphoid cell lines and non-Hodgkin's lymphomas
54. The action of Bax and bcl-2 on T cell selection
55. Daxx, a novel Fas-binding protein that activates JNK and apoptosis
56. p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice