A point mutation in CD28 distinguishes proliferative signals from survival signals

Nature Immunology

Volumn 2, Issue 4, 2001, Pages 325-332

  Okkenhaug, Klaus ^a,b,f   Wu, Linda ^a,b   Garza, Kristine M ^b   La Rose, Jose ^b   Khoo, Wilson ^c   Odermatt, Bernhard ^d   Mak, Tak W ^a,b,c   Ohashi, Pamela S ^a,b   Rottapel, Robert ^a,b,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c AMGEN INSTITUTE   (Canada)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e ST MICHAEL'S HOSPITAL   (Canada)

^f LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BCL2L1 PROTEIN, HUMAN; BCL2L1 PROTEIN, MOUSE; CD28 ANTIGEN; IMMUNOGLOBULIN; INTERLEUKIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN BCL X; TYROSINE;

ANIMAL; ARTICLE; B LYMPHOCYTE; BIOSYNTHESIS; C57BL MOUSE; CELL DIVISION; CELL SURVIVAL; CHEMISTRY; CLONAL ANERGY; CYTOLOGY; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; METABOLISM; MOUSE; MOUSE MUTANT; PHOSPHORYLATION; POINT MUTATION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; T LYMPHOCYTE; TRANSGENIC MOUSE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS, CD28; B-LYMPHOCYTES; BCL-X PROTEIN; CELL DIVISION; CELL SURVIVAL; CLONAL ANERGY; GENE EXPRESSION; HUMANS; IMMUNOGLOBULINS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COOPERATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PHOSPHORYLATION; POINT MUTATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTES; TYROSINE;

EID: 0035319244     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/86327     Document Type: Article

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