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Volumn 18, Issue , 2000, Pages 83-111

Population biology of lymphocytes: The flight for survival

Author keywords

Lymphocyte competition; Lymphocyte homeostasis; Lymphocyte survival and life spans; Naive and memory lymphocytes

Indexed keywords

CELL SURVIVAL; HOMEOSTASIS; IMMUNE RESPONSE; LIFESPAN; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE;

EID: 0034080178     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.18.1.83     Document Type: Review
Times cited : (392)

References (162)
  • 2
    • 0004149207 scopus 로고
    • Oxford, UK: Oxford Univ. Press
    • Dawkins R. 1989. The Selfish Gene. Oxford, UK: Oxford Univ. Press
    • (1989) The Selfish Gene
    • Dawkins, R.1
  • 5
    • 0030769190 scopus 로고    scopus 로고
    • Lymphocyte survival: A red queen hypothesis
    • Freitas AA, Rocha B. 1997. Lymphocyte survival: a red queen hypothesis. Science 277:1950
    • (1997) Science , vol.277 , pp. 1950
    • Freitas, A.A.1    Rocha, B.2
  • 6
    • 0027402403 scopus 로고
    • Lymphocyte lifespans: Homeostasis, selection and competition
    • Freitas AA, Rocha B. 1993. Lymphocyte lifespans: homeostasis, selection and competition. Immunol. Today. 14:25-29
    • (1993) Immunol. Today. , vol.14 , pp. 25-29
    • Freitas, A.A.1    Rocha, B.2
  • 7
    • 0002027029 scopus 로고
    • A new evolutionary law
    • Van Valen L. 1973. A new evolutionary law. Evol. Theory 1:1-30
    • (1973) Evol. Theory , vol.1 , pp. 1-30
    • Van Valen, L.1
  • 8
    • 0030873556 scopus 로고    scopus 로고
    • Differential requirements for survival and proliferation of CDS naive or memory T cells
    • Tanchot C, Lemonnier FA, Perarnau B, Freitas AA, Rocha B. 1997. Differential requirements for survival and proliferation of CDS naive or memory T cells. Science 276:2057-62
    • (1997) Science , vol.276 , pp. 2057-2062
    • Tanchot, C.1    Lemonnier, F.A.2    Perarnau, B.3    Freitas, A.A.4    Rocha, B.5
  • 9
    • 0029007317 scopus 로고
    • Positive selection of T cells: Rescue from programmed cell death and differentiation require continual engagement of the T cell receptor
    • Kisielow P, Miazek A. 1995. Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor. J. Exp. Med. 181:1975-84
    • (1995) J. Exp. Med. , vol.181 , pp. 1975-1984
    • Kisielow, P.1    Miazek, A.2
  • 11
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher H, Burki K, Lang R, Hengartner H, Zinkernagel RM. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342:559-61
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 13
    • 0030775139 scopus 로고    scopus 로고
    • Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complexencoded molecules
    • Kirberg J, Berns A, von Boehmer H. 1997. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complexencoded molecules. J. Exp. Med. 186:1269-75
    • (1997) J. Exp. Med. , vol.186 , pp. 1269-1275
    • Kirberg, J.1    Berns, A.2    Von Boehmer, H.3
  • 14
    • 0033136944 scopus 로고    scopus 로고
    • Designing and maintaining the mature TCR repertoire: The continuum of selfpeptide: Self-MHC complex recognition
    • Viret C, Wong FS, Janeway CA. 1999. Designing and maintaining the mature TCR repertoire: the continuum of selfpeptide: self-MHC complex recognition. Immunity 10:559-68
    • (1999) Immunity , vol.10 , pp. 559-568
    • Viret, C.1    Wong, F.S.2    Janeway, C.A.3
  • 15
    • 0030849637 scopus 로고    scopus 로고
    • Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
    • Rooke R, Waltzinger C, Benoist C, Mathis D. 1997. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. Immunity 7:123-34
    • (1997) Immunity , vol.7 , pp. 123-134
    • Rooke, R.1    Waltzinger, C.2    Benoist, C.3    Mathis, D.4
  • 18
    • 0030727150 scopus 로고    scopus 로고
    • Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
    • Brocker T. 1997. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J. Exp. Med. 186:1223-32
    • (1997) J. Exp. Med. , vol.186 , pp. 1223-1232
    • Brocker, T.1
  • 19
    • 0031889305 scopus 로고    scopus 로고
    • TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host
    • Beutner U, MacDonald HR. 1998. TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host. Int. Immunol. 10:305-10
    • (1998) Int. Immunol. , vol.10 , pp. 305-310
    • Beutner, U.1    MacDonald, H.R.2
  • 20
    • 0030048126 scopus 로고    scopus 로고
    • H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
    • Martin WD, Hicks GG, Mendiratta SK, Leva HI, Ruley HE, Van Kaer L. 1996. H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Cell 84:543-50
    • (1996) Cell , vol.84 , pp. 543-550
    • Martin, W.D.1    Hicks, G.G.2    Mendiratta, S.K.3    Leva, H.I.4    Ruley, H.E.5    Van Kaer, L.6
  • 21
    • 0033517155 scopus 로고    scopus 로고
    • + T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection
    • + T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J. Exp. Med. 190:367-74
    • (1999) J. Exp. Med. , vol.190 , pp. 367-374
    • Bender, J.1    Mitchell, T.2    Kapler, J.3    Marrack, P.4
  • 22
    • 0027461784 scopus 로고
    • The life span of naive aβ T cells in secondary lymphoid organs
    • von Boehmer H, Hafen K. 1993. The life span of naive aβ T cells in secondary lymphoid organs. J. Exp. Med. 177:891-96
    • (1993) J. Exp. Med. , vol.177 , pp. 891-896
    • Von Boehmer, H.1    Hafen, K.2
  • 23
    • 0028267677 scopus 로고
    • Turnover of naive-and memory-phenotype T cells
    • Tough DF, Sprent J. 1994. Turnover of naive-and memory-phenotype T cells. J. Exp. Med. 179:1127-35
    • (1994) J. Exp. Med. , vol.179 , pp. 1127-1135
    • Tough, D.F.1    Sprent, J.2
  • 24
    • 0028988325 scopus 로고
    • On the cellular basis of immunological T cell memory
    • Bruno L, Kirberg J, von Boehmer H. 1995. On the cellular basis of immunological T cell memory. Immunity 2:37-43
    • (1995) Immunity , vol.2 , pp. 37-43
    • Bruno, L.1    Kirberg, J.2    Von Boehmer, H.3
  • 25
    • 0033081225 scopus 로고    scopus 로고
    • The common cytokine receptor gamma chain and the pre-T cell receptor provide independent but critically overlapping signals in early alpha/beta T cell development
    • DiSanto JP, Aifantis I, Rosmaraki E, Garcia C, Feinberg J, Fehling HJ, Fischer A, von Boehmer H, Rocha B. 1999. The common cytokine receptor gamma chain and the pre-T cell receptor provide independent but critically overlapping signals in early alpha/beta T cell development. J. Exp. Med. 189:563-73
    • (1999) J. Exp. Med. , vol.189 , pp. 563-573
    • DiSanto, J.P.1    Aifantis, I.2    Rosmaraki, E.3    Garcia, C.4    Feinberg, J.5    Fehling, H.J.6    Fischer, A.7    Von Boehmer, H.8    Rocha, B.9
  • 29
    • 0032482996 scopus 로고    scopus 로고
    • Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation
    • Gett AV, Hodgkin PD. 1998. Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc. Natl. Acad. Sci. USA 95:9488-93
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9488-9493
    • Gett, A.V.1    Hodgkin, P.D.2
  • 31
    • 0027408670 scopus 로고
    • High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virusinduced polyclonal cytotoxic T lymphocyte response
    • Nahill SR, Welsh RM. 1993. High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virusinduced polyclonal cytotoxic T lymphocyte response. / Exp. Med. 177:317-27
    • (1993) J. Exp. Med. , vol.177 , pp. 317-327
    • Nahill, S.R.1    Welsh, R.M.2
  • 32
    • 0030036342 scopus 로고    scopus 로고
    • Induction of bystander T cell proliferation by viruses and Type I interferon in vivo
    • Tough DF, Borrow P, Sprent J. 1996. Induction of bystander T cell proliferation by viruses and Type I interferon in vivo. Science 272:1947-50
    • (1996) Science , vol.272 , pp. 1947-1950
    • Tough, D.F.1    Borrow, P.2    Sprent, J.3
  • 34
    • 0019985656 scopus 로고
    • Recognition of self, balance of growth and competition: Horizontal networks regulate immune responsiveness
    • Grossman Z. 1982. Recognition of self, balance of growth and competition: horizontal networks regulate immune responsiveness. Eur. J. Immunol. 12: 747-56
    • (1982) Eur. J. Immunol. , vol.12 , pp. 747-756
    • Grossman, Z.1
  • 36
    • 0033577864 scopus 로고    scopus 로고
    • Developmental regulation of Lck targeting to the CDS coreceptor controls signaling in naive and memory T cells
    • Bachmann MF, Gallimore A, Linkert S, Cerundolo V, Lanzavecchia A, Kopf M, Viola A. 1999. Developmental regulation of Lck targeting to the CDS coreceptor controls signaling in naive and memory T cells. J. Exp. Med. 189:1521-30
    • (1999) J. Exp. Med. , vol.189 , pp. 1521-1530
    • Bachmann, M.F.1    Gallimore, A.2    Linkert, S.3    Cerundolo, V.4    Lanzavecchia, A.5    Kopf, M.6    Viola, A.7
  • 38
    • 0024332461 scopus 로고
    • Peripheral T lymphocytes: Expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios "in vivo"
    • Rocha B, Dautigny N, Pereira P. 1989. Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios "in vivo". Eur. J. Immunol. 19:905-11
    • (1989) Eur. J. Immunol. , vol.19 , pp. 905-911
    • Rocha, B.1    Dautigny, N.2    Pereira, P.3
  • 41
    • 0027972541 scopus 로고
    • The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen
    • Mullbacher A. 1994. The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen. J. Exp. Med. 179:317-21
    • (1994) J. Exp. Med. , vol.179 , pp. 317-321
    • Mullbacher, A.1
  • 42
    • 0029157149 scopus 로고
    • Laser light suicide of proliferating virusspecific CDS+ T cells in an in vivo response
    • Tripp RA, Lahti JM, Doherty PC. 1995. Laser light suicide of proliferating virusspecific CDS+ T cells in an in vivo response. J. Immitnol. 155:3719-21
    • (1995) J. Immitnol. , vol.155 , pp. 3719-3721
    • Tripp, R.A.1    Lahti, J.M.2    Doherty, P.C.3
  • 43
    • 0030949555 scopus 로고    scopus 로고
    • Factors controlling the turnover of T memory cells
    • Sprent J, Tough DF, Sun S. 1997. Factors controlling the turnover of T memory cells. Immunol. Rev. 156:79-85
    • (1997) Immunol. Rev. , vol.156 , pp. 79-85
    • Sprent, J.1    Tough, D.F.2    Sun, S.3
  • 45
    • 0021690947 scopus 로고
    • T cell repopulation from functionally restricted splenic progenitors: 10,000-fold expansion documented by using limiting dilution analyses
    • Miller RA, Stutman O. 1984. T cell repopulation from functionally restricted splenic progenitors: 10,000-fold expansion documented by using limiting dilution analyses. J. Immunol. 133:2925-32
    • (1984) J. Immunol. , vol.133 , pp. 2925-2932
    • Miller, R.A.1    Stutman, O.2
  • 47
    • 18744435046 scopus 로고    scopus 로고
    • Restoration of T-cell homeostasis after T-cell depletion
    • Mackall CL, Hakim FT, Gress RE. 1997. Restoration of T-cell homeostasis after T-cell depletion. Semin. Immunol. 9:339-46
    • (1997) Semin. Immunol. , vol.9 , pp. 339-346
    • Mackall, C.L.1    Hakim, F.T.2    Gress, R.E.3
  • 48
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce JP, Boone DL, Chai S, Swain RE, Dassopoulos T, Trettin S, Ma A. 1998. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9:669-76
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1    Boone, D.L.2    Chai, S.3    Swain, R.E.4    Dassopoulos, T.5    Trettin, S.6    Ma, A.7
  • 49
    • 0028821858 scopus 로고
    • Immunopathology of interleukin (IL) 2-deficient mice: Thymus dependence and suppression by thymus-dependent cells with an intact IL-2 gene
    • Kramer S, Schimpl A, Hunig T. 1995. Immunopathology of interleukin (IL) 2-deficient mice: thymus dependence and suppression by thymus-dependent cells with an intact IL-2 gene. /. Exp. Med. 182:1769-76
    • (1995) Exp. Med. , vol.182 , pp. 1769-1776
    • Kramer, S.1    Schimpl, A.2    Hunig, T.3
  • 50
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn R, Lohler J, Rennick D, Rajewsky K, Muller W. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263-74
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 52
    • 0031569514 scopus 로고    scopus 로고
    • Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor
    • Van Parijs L, Biuckians A, Ibragimov A, Alt FW, Willerford DM, Abbas AK. 1997. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. J. Immunol. 158:3738-45
    • (1997) J. Immunol. , vol.158 , pp. 3738-3745
    • Van Parijs, L.1    Biuckians, A.2    Ibragimov, A.3    Alt, F.W.4    Willerford, D.M.5    Abbas, A.K.6
  • 53
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • Lam K-P, Kuhn R, Rajewsky K. 1997. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90:1073-83
    • (1997) Cell , vol.90 , pp. 1073-1083
    • Lam, K.-P.1    Kuhn, R.2    Rajewsky, K.3
  • 54
    • 0025852445 scopus 로고
    • A B-cell deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
    • Kitamura D, Roes J, Kühn R, Rajewsky K. 1991. A B-cell deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350:423-26
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kühn, R.3    Rajewsky, K.4
  • 55
  • 56
    • 0030058466 scopus 로고    scopus 로고
    • Aberrant B cell development and immune response in mice with a compromised BCR complex
    • Torres RM, Flaswinkel H, Reth M, Rajewsky K. 1996. Aberrant B cell development and immune response in mice with a compromised BCR complex. Science 272:1804-8
    • (1996) Science , vol.272 , pp. 1804-1808
    • Torres, R.M.1    Flaswinkel, H.2    Reth, M.3    Rajewsky, K.4
  • 57
    • 0031692641 scopus 로고    scopus 로고
    • The role of the B cell receptor V region in periph-eral B cell survival
    • Rosado MM, Freitas AA. 1998. The role of the B cell receptor V region in periph-eral B cell survival. Eur. J. Immunol. 28:2685-93
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2685-2693
    • Rosado, M.M.1    Freitas, A.A.2
  • 58
    • 0029379728 scopus 로고
    • Pre-B cell development in the absence of lambdaS in transgenic mice expressing a heavy-chain disease protein
    • Corcos D, Dunda O, Butor C, Cesbron JY, Lores P, Buchinni D, Jami J. 1995. Pre-B cell development in the absence of lambdaS in transgenic mice expressing a heavy-chain disease protein. Curr. Biol. 5:1140-48
    • (1995) Curr. Biol. , vol.5 , pp. 1140-1148
    • Corcos, D.1    Dunda, O.2    Butor, C.3    Cesbron, J.Y.4    Lores, P.5    Buchinni, D.6    Jami, J.7
  • 60
    • 0024461281 scopus 로고
    • Expression of antibody V-regions is genetically and developmentally controled and modulated by the B lymphocyte environment
    • Freitas AA, Lembezat MP, Coutinho A. 1989. Expression of antibody V-regions is genetically and developmentally controled and modulated by the B lymphocyte environment. Int. Immunol. 1:342-54
    • (1989) Int. Immunol. , vol.1 , pp. 342-354
    • Freitas, A.A.1    Lembezat, M.P.2    Coutinho, A.3
  • 61
    • 0027165835 scopus 로고
    • V region dependent selection of persistent resting peripheral B cells in normal mice
    • Viale AC, Coutinho A, Heyman RA, Freitas AA. 1993. V region dependent selection of persistent resting peripheral B cells in normal mice. Int. Immunol. 5:599-605
    • (1993) Int. Immunol. , vol.5 , pp. 599-605
    • Viale, A.C.1    Coutinho, A.2    Heyman, R.A.3    Freitas, A.A.4
  • 62
    • 0025198395 scopus 로고
    • Selection of VH gene repertoires: Differentiating B cells of adult bone marrow mimic fetal development
    • Freitas AA, Andrade L, Lembezat MP, Coutinho A. 1990. Selection of VH gene repertoires: differentiating B cells of adult bone marrow mimic fetal development. Int. Immunol. 2:15-23
    • (1990) Int. Immunol. , vol.2 , pp. 15-23
    • Freitas, A.A.1    Andrade, L.2    Lembezat, M.P.3    Coutinho, A.4
  • 64
    • 0023821642 scopus 로고
    • Secondary antibody responses to thymus-independant antigens. Decline and life-span of memory
    • Colle JH, Truffa-Bachi P, Freitas AA. 1988. Secondary antibody responses to thymus-independant antigens. Decline and life-span of memory. Eur. J. Immunol. 18:1307-14
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1307-1314
    • Colle, J.H.1    Truffa-Bachi, P.2    Freitas, A.A.3
  • 65
    • 0023761867 scopus 로고
    • B-cell memory is short-lived in the absence of antigen
    • Gray D, Skarvall H. 1988. B-cell memory is short-lived in the absence of antigen. Nature 336:70-73
    • (1988) Nature , vol.336 , pp. 70-73
    • Gray, D.1    Skarvall, H.2
  • 66
    • 0024989657 scopus 로고
    • Maintenance of B-cell memory by long-lived cells generated from proliferating precursors
    • Schittek B, Rajewsky K. 1990. Maintenance of B-cell memory by long-lived cells generated from proliferating precursors. Nature 346:749-51
    • (1990) Nature , vol.346 , pp. 749-751
    • Schittek, B.1    Rajewsky, K.2
  • 67
    • 0032573147 scopus 로고    scopus 로고
    • Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo
    • Lam KP, Rajewsky K. 1998. Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo. Proc. Natl. Acad. Sci. USA 95:13171-75
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13171-13175
    • Lam, K.P.1    Rajewsky, K.2
  • 68
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay D, Saunders T, Camper S, Weigert M. 1993. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177(4):999-1008
    • (1993) J. Exp. Med. , vol.177 , Issue.4 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 69
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B cells
    • Tiegs SL, Russell DM, Nemazee D. 1993. Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177:1009-20
    • (1993) J. Exp. Med. , vol.177 , pp. 1009-1020
    • Tiegs, S.L.1    Russell, D.M.2    Nemazee, D.3
  • 70
    • 0032487518 scopus 로고    scopus 로고
    • Receptor editing occurs frequently during normal B cell development
    • Retter MW, Nemazee D. 1998. Receptor editing occurs frequently during normal B cell development. J. Exp. Med. 188:1231-38
    • (1998) J. Exp. Med. , vol.188 , pp. 1231-1238
    • Retter, M.W.1    Nemazee, D.2
  • 71
    • 0029864365 scopus 로고    scopus 로고
    • Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection
    • DiSanto JP, Guy-Grand D, Fisher A, Tarakhovsky A. 1996. Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection. J. Exp. Med. 183:1111-18
    • (1996) J. Exp. Med. , vol.183 , pp. 1111-1118
    • DiSanto, J.P.1    Guy-Grand, D.2    Fisher, A.3    Tarakhovsky, A.4
  • 72
    • 0030823769 scopus 로고    scopus 로고
    • LKLF: A transcriptional regulator of single-positive T cell quiescence and survival
    • Kuo CT, Veselits ML, Leiden JM. 1997. LKLF: a transcriptional regulator of single-positive T cell quiescence and survival. Science 277:1986-90
    • (1997) Science , vol.277 , pp. 1986-1990
    • Kuo, C.T.1    Veselits, M.L.2    Leiden, J.M.3
  • 73
    • 0032167830 scopus 로고    scopus 로고
    • The transcription factor NFAT4 is involved in the generation and survival of T cells
    • Oukka M, Ho I-C, de la Brousse FC, Hoey T, Grusby MJ, GlimcherLH. 1998. The transcription factor NFAT4 is involved in the generation and survival of T Cells. Immunity 9:295-304
    • (1998) Immunity , vol.9 , pp. 295-304
    • Oukka, M.1    Ho, I.-C.2    De La Brousse, F.C.3    Hoey, T.4    Grusby, M.J.5
  • 74
    • 0032169313 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals
    • Caldwell RG, Wilson JB, Anderson SJ, Longnecker R. 1998. Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity 9:405-11
    • (1998) Immunity , vol.9 , pp. 405-411
    • Caldwell, R.G.1    Wilson, J.B.2    Anderson, S.J.3    Longnecker, R.4
  • 77
    • 0031456145 scopus 로고    scopus 로고
    • Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool
    • Turner M, Gulbranson-Judge A, Quinn ME, Walters AE, MacLennan IC, Tybulewicz VL. 1997. Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool. J. Exp. Med. 186:2013-21
    • (1997) J. Exp. Med. , vol.186 , pp. 2013-2021
    • Turner, M.1    Gulbranson-Judge, A.2    Quinn, M.E.3    Walters, A.E.4    Maclennan, I.C.5    Tybulewicz, V.L.6
  • 78
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses
    • Sha WC, Liou HC, Tuomanen EI, Baltimore D. 1995. Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses. Cell 80:321-30
    • (1995) Cell , vol.80 , pp. 321-330
    • Sha, W.C.1    Liou, H.C.2    Tuomanen, E.I.3    Baltimore, D.4
  • 79
    • 0029967024 scopus 로고    scopus 로고
    • B-cell-specific coactivator OBF-1/OCA-B/ Bob1 required for immune response and germinal centre formation
    • Schubart DB, Relink A, Kosco-Vilbois MH, Botteri F, Matthias P. 1996. B-cell-specific coactivator OBF-1/OCA-B/ Bob1 required for immune response and germinal centre formation. Nature 383:538-42
    • (1996) Nature , vol.383 , pp. 538-542
    • Schubart, D.B.1    Relink, A.2    Kosco-Vilbois, M.H.3    Botteri, F.4    Matthias, P.5
  • 80
    • 0032575688 scopus 로고    scopus 로고
    • The bcl-2 protein family: Arbiters of cell survival
    • Adams JM, Cory S. 1998. The bcl-2 protein family: arbiters of cell survival. Sciience 281:1322-26
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 81
    • 0031918223 scopus 로고    scopus 로고
    • Bcl-2 family: Regulators of cell death
    • Chao DT, Korsmeyer SJ. 1998. Bcl-2 family: regulators of cell death. Annu. Rev. Immunol 16:395-419
    • (1998) Annu. Rev. Immunol , vol.16 , pp. 395-419
    • Chao, D.T.1    Korsmeyer, S.J.2
  • 82
    • 0033491603 scopus 로고    scopus 로고
    • Recent progress on the regulation of apoptosis by Bc1-2 family members
    • Minn AJ, Swain RE, Ma A, Thompson CB. 1998. Recent progress on the regulation of apoptosis by Bc1-2 family members. Adv. Immunol. 70:245-79
    • (1998) Adv. Immunol. , vol.70 , pp. 245-279
    • Minn, A.J.1    Swain, R.E.2    Ma, A.3    Thompson, C.B.4
  • 83
    • 0013842165 scopus 로고
    • Multiple thymus grafts in aged mice
    • Metcalf D. 1965. Multiple thymus grafts in aged mice. Nature 208:87-88
    • (1965) Nature , vol.208 , pp. 87-88
    • Metcalf, D.1
  • 85
    • 0032101049 scopus 로고    scopus 로고
    • The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool
    • Berzins SP, Boyd RL, Miller JF. 1998. The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool. J. Exp. Med. 187:1839-48
    • (1998) J. Exp. Med. , vol.187 , pp. 1839-1848
    • Berzins, S.P.1    Boyd, R.L.2    Miller, J.F.3
  • 86
    • 0030769486 scopus 로고    scopus 로고
    • Independent homeostatic regulation of B cell compartments
    • Agenes F, Rosado MM, Freitas AA. 1997. Independent homeostatic regulation of B cell compartments. Eur. J. Immunol. 27:1801-7
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1801-1807
    • Agenes, F.1    Rosado, M.M.2    Freitas, A.A.3
  • 88
    • 0001921248 scopus 로고
    • Competition and niche theory
    • ed. RM May, Oxford, UK: Blackwell's Sci.
    • Pianka ER. 1976. Competition and niche theory. In Theoretical Ecology. Principles and Applications, ed. RM May, pp. 114-41. Oxford, UK: Blackwell's Sci.
    • (1976) Theoretical Ecology. Principles and Applications , pp. 114-141
    • Pianka, E.R.1
  • 89
    • 0029049941 scopus 로고
    • The role of cellular competition in B cell survival and selection of B cell repertoires
    • Freitas AA, Rosado M, Viale A-C, Grandien A. 1995. The role of cellular competition in B cell survival and selection of B cell repertoires. Eur. J. Immunol. 25:1729-38
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1729-1738
    • Freitas, A.A.1    Rosado, M.2    Viale, A.-C.3    Grandien, A.4
  • 90
    • 0029954114 scopus 로고    scopus 로고
    • Cellular competition modulates the survival and selection of CDS T cells
    • Freitas AA, Agenes F, Coutinho GC. 1996. Cellular competition modulates the survival and selection of CDS T cells. Eur. J. Immunol. 26:2640-49
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2640-2649
    • Freitas, A.A.1    Agenes, F.2    Coutinho, G.C.3
  • 91
    • 0029550111 scopus 로고
    • Antigeninduced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate
    • Cyster JG, Goodnow CC. 1995. Antigeninduced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate. Immunity 3:691-701
    • (1995) Immunity , vol.3 , pp. 691-701
    • Cyster, J.G.1    Goodnow, C.C.2
  • 92
    • 0020346563 scopus 로고
    • Resource competition and community structure
    • Princeton, NJ: Princeton Univ. Press
    • Tilman D. 1982. Resource competition and community structure. Monographs in Population Biology, Vol. 17. Princeton, NJ: Princeton Univ. Press
    • (1982) Monographs in Population Biology , vol.17
    • Tilman, D.1
  • 93
    • 0000369563 scopus 로고
    • La technique de culture continue; théorie et applications
    • Monod J. 1950. La technique de culture continue; théorie et applications. Ann. Inst. Pasteur. 79:390-410
    • (1950) Ann. Inst. Pasteur. , vol.79 , pp. 390-410
    • Monod, J.1
  • 95
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: Understanding their relation
    • Ahmed R, Gray D. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54-57
    • (1996) Science , vol.272 , pp. 54-57
    • Ahmed, R.1    Gray, D.2
  • 96
    • 0028163309 scopus 로고
    • Experimental evidence that competition promotes divergence in daptive radiation
    • Schulter D. 1994. Experimental evidence that competition promotes divergence in daptive radiation. Science 266:798-800
    • (1994) Science , vol.266 , pp. 798-800
    • Schulter, D.1
  • 97
    • 0003312262 scopus 로고    scopus 로고
    • The role of space in population dynamics and interspecific interactions
    • Princeton, NJ: Princeton Univ. Press
    • Tilman D, Kareiva P. 1997. The role of space in population dynamics and interspecific interactions. Monographs in Population Biology, Vol. 30. Princeton, NJ: Princeton Univ. Press
    • (1997) Monographs in Population Biology , vol.30
    • Tilman, D.1    Kareiva, P.2
  • 98
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher EC, Picker JJ. 1996. Lymphocyte homing and homeostasis. Science 272:60-66
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, J.J.2
  • 99
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster JG, Hartley SB, Goodnow CC. 1994. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 371:389-95
    • (1994) Nature , vol.371 , pp. 389-395
    • Cyster, J.G.1    Hartley, S.B.2    Goodnow, C.C.3
  • 100
    • 0030582773 scopus 로고    scopus 로고
    • A putative chemokine receptor, BLRl, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
    • Forster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. 1996. A putative chemokine receptor, BLRl, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037-47
    • (1996) Cell , vol.87 , pp. 1037-1047
    • Forster, R.1    Mattis, A.E.2    Kremmer, E.3    Wolf, E.4    Brem, G.5    Lipp, M.6
  • 101
    • 0029813991 scopus 로고    scopus 로고
    • Thymic medulla epithelial cells acquire specific markers by post-mitotic maturation
    • Penit C, Lucas B, Vasseur F, Rieker T, Boyd RL. 1996. Thymic medulla epithelial cells acquire specific markers by post-mitotic maturation. Dev. Immunol. 5:25-36
    • (1996) Dev. Immunol. , vol.5 , pp. 25-36
    • Penit, C.1    Lucas, B.2    Vasseur, F.3    Rieker, T.4    Boyd, R.L.5
  • 102
    • 0032489912 scopus 로고    scopus 로고
    • The sequential role of lymphotoxin and B cells in the development of splenic follicles
    • Gonzalez M, Mackay F, Browning JL, Kosco-Vilbois MH, Noelle RJ. 1998. The sequential role of lymphotoxin and B cells in the development of splenic follicles. /. Exp. Med. 187:997-1007
    • (1998) Exp. Med. , vol.187 , pp. 997-1007
    • Gonzalez, M.1    Mackay, F.2    Browning, J.L.3    Kosco-Vilbois, M.H.4    Noelle, R.J.5
  • 103
    • 0032489920 scopus 로고    scopus 로고
    • B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion
    • Fu YX, Huang G, Wang Y, Chaplin DD. 1998. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion. / Exp. Med. 187:1009-18
    • (1998) J. Exp. Med. , vol.187 , pp. 1009-1018
    • Fu, Y.X.1    Huang, G.2    Wang, Y.3    Chaplin, D.D.4
  • 104
    • 0033521542 scopus 로고    scopus 로고
    • Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells
    • Endres R, Alimzhanov MB, Plitz T, Fut-terer A, Kosco-Vilbois MH, Nedospasov SA, Rajewsky K, Pfeffer K. 1999. Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells. J. Exp. Med. 189:159-68
    • (1999) J. Exp. Med. , vol.189 , pp. 159-168
    • Endres, R.1    Alimzhanov, M.B.2    Plitz, T.3    Fut-Terer, A.4    Kosco-Vilbois, M.H.5    Nedospasov, S.A.6    Rajewsky, K.7    Pfeffer, K.8
  • 107
    • 0030938144 scopus 로고    scopus 로고
    • Germinal center development
    • Liu YJ, Arpin C. 1997. Germinal center development. Immunol. Rev. 156:111-26
    • (1997) Immunol. Rev. , vol.156 , pp. 111-126
    • Liu, Y.J.1    Arpin, C.2
  • 108
    • 0027198363 scopus 로고
    • Somatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglob-ulin heavy chain diversity
    • Hinds-Frey KR, Nishikata H, Litman RT, Litman GW. 1993. Somatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglob-ulin heavy chain diversity. J. Exp. Med. 178:815-24
    • (1993) J. Exp. Med. , vol.178 , pp. 815-824
    • Hinds-Frey, K.R.1    Nishikata, H.2    Litman, R.T.3    Litman, G.W.4
  • 109
    • 0020464104 scopus 로고
    • The range and fine specificity of the anti-hapten immune response: Phylogenetic studies
    • Litman GW, Stolen JS, Sarvas HO, Makela O. 1982. The range and fine specificity of the anti-hapten immune response: phylogenetic studies. J. Immunogenet. 9:465-74
    • (1982) J. Immunogenet. , vol.9 , pp. 465-474
    • Litman, G.W.1    Stolen, J.S.2    Sarvas, H.O.3    Makela, O.4
  • 110
    • 0024489294 scopus 로고
    • Differential L chain expression in the antibody responses to phosphorylcholine of adult bone marrow or peritoneum-derived B lymphocytes
    • Cazenave PA, Martinez C, Coutinho A. 1989. Differential L chain expression in the antibody responses to phosphorylcholine of adult bone marrow or peritoneum-derived B lymphocytes. J. Immunol. 142:8-11
    • (1989) J. Immunol. , vol.142 , pp. 8-11
    • Cazenave, P.A.1    Martinez, C.2    Coutinho, A.3
  • 112
    • 0013860844 scopus 로고
    • Thymus-dependent areas in the lymphoid organs of neonatally thymectomized mice
    • Parrott DV, De Sousa MA, East J. 1966. Thymus-dependent areas in the lymphoid organs of neonatally thymectomized mice. J. Exp. Med. 123:191-204
    • (1966) J. Exp. Med. , vol.123 , pp. 191-204
    • Parrott, D.V.1    De Sousa, M.A.2
  • 114
    • 0026317875 scopus 로고
    • Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting
    • Mombaerts P, Clarke AR, Hooper ML, Tonegawa S. 1991. Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting. Proc. Nall. Acad. Sci. USA 88:3084-87
    • (1991) Proc. Nall. Acad. Sci. USA , vol.88 , pp. 3084-3087
    • Mombaerts, P.1    Clarke, A.R.2    Hooper, M.L.3    Tonegawa, S.4
  • 118
    • 0031766182 scopus 로고    scopus 로고
    • The organization of mature T-cell pools
    • Tanchot C, Rocha B. 1998. The organization of mature T-cell pools. Immunol. Today 19:575-79
    • (1998) Immunol. Today , vol.19 , pp. 575-579
    • Tanchot, C.1    Rocha, B.2
  • 119
    • 0030779119 scopus 로고    scopus 로고
    • Peripheral selection of T cell repertoires: The role of continuous thymus output
    • Tanchot C, Rocha B. 1997. Peripheral selection of T cell repertoires: the role of continuous thymus output. J. Exp. Med. 186:1099-1106
    • (1997) J. Exp. Med. , vol.186 , pp. 1099-1106
    • Tanchot, C.1    Rocha, B.2
  • 120
    • 0029984776 scopus 로고    scopus 로고
    • Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterelogous viral infection
    • Selin LK, Vergilis K, Welsh RM, Nahill SR. 1996. Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterelogous viral infection. J. Exp. Med. 183:2489-99
    • (1996) J. Exp. Med. , vol.183 , pp. 2489-2499
    • Selin, L.K.1    Vergilis, K.2    Welsh, R.M.3    Nahill, S.R.4
  • 121
    • 0033579933 scopus 로고    scopus 로고
    • Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population
    • Agenes F, Freitas AA. 1999. Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population. J. Exp. Med. 189:319-30
    • (1999) J. Exp. Med. , vol.189 , pp. 319-330
    • Agenes, F.1    Freitas, A.A.2
  • 123
    • 0033166040 scopus 로고    scopus 로고
    • T-cell function in newbom mice and humans
    • Adkins B. 1999. T-cell function in newbom mice and humans. Immunol, Today 20:330-35
    • (1999) Immunol, Today , vol.20 , pp. 330-335
    • Adkins, B.1
  • 125
    • 0029585494 scopus 로고
    • Neonatal impaired response to viral superantigen encoded by MMTV(SW) and Mtv-7
    • Le Bon A, Desaymard C, Papiernik M. 1995. Neonatal impaired response to viral superantigen encoded by MMTV(SW) and Mtv-7. Int. Immund. 7:1897-1903
    • (1995) Int. Immund. , vol.7 , pp. 1897-1903
    • Le Bon, A.1    Desaymard, C.2    Papiernik, M.3
  • 126
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • Billingham RE, Brent L, Medawar PB. 1953. Actively acquired tolerance of foreign cells. Nature 172:603
    • (1953) Nature , vol.172 , pp. 603
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 127
    • 0029552310 scopus 로고
    • Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire
    • Gavin MA, Bevan MJ. 1995. Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire. Immunity 3:793-800
    • (1995) Immunity , vol.3 , pp. 793-800
    • Gavin, M.A.1    Bevan, M.J.2
  • 128
    • 0021279678 scopus 로고
    • Reactions among IgM antibodies derived from normal, neonatal mice
    • Holmberg D, Forsgren S, Ivars F, Coutinho A. 1984. Reactions among IgM antibodies derived from normal, neonatal mice. Eur. J. Immunol. 14:435-41
    • (1984) Eur. J. Immunol. , vol.14 , pp. 435-441
    • Holmberg, D.1    Forsgren, S.2    Ivars, F.3    Coutinho, A.4
  • 129
    • 0022931326 scopus 로고
    • Antibody repertoires of normal BALB/c mice: B lymphocyte populations defined by state of activation
    • Holmberg D, Freitas AA, Portnoi D, Jacquemart F, Avrameas S, Coutinho A. 1986. Antibody repertoires of normal BALB/c mice: B lymphocyte populations defined by state of activation. Immunol. Rev. 93:147-69
    • (1986) Immunol. Rev. , vol.93 , pp. 147-169
    • Holmberg, D.1    Freitas, A.A.2    Portnoi, D.3    Jacquemart, F.4    Avrameas, S.5    Coutinho, A.6
  • 130
    • 0024425234 scopus 로고
    • Lymphocyte population kinetics during the development of the immune system. B cell persistance and life span can be determined by the host environment
    • Thomas-Vaslin V, Freitas AA. 1989. Lymphocyte population kinetics during the development of the immune system. B cell persistance and life span can be determined by the host environment. Int. Immunol. 1:237-46
    • (1989) Int. Immunol. , vol.1 , pp. 237-246
    • Thomas-Vaslin, V.1    Freitas, A.A.2
  • 132
    • 0028957496 scopus 로고
    • Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance
    • Rocha B, Grandien A, Freitas AA. 1995. Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance. J. Exp. Med. 181:993-1003
    • (1995) J. Exp. Med. , vol.181 , pp. 993-1003
    • Rocha, B.1    Grandien, A.2    Freitas, A.A.3
  • 135
    • 0029659048 scopus 로고    scopus 로고
    • Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CDS
    • Cobbold SP, Adams E, Marshall SE, Davies JD, Waldmann H. 1996. Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CDS. Immunol. Rev. 149:5-33
    • (1996) Immunol. Rev. , vol.149 , pp. 5-33
    • Cobbold, S.P.1    Adams, E.2    Marshall, S.E.3    Davies, J.D.4    Waldmann, H.5
  • 137
    • 0028057419 scopus 로고
    • Reduced life span of anergic self-reactive B cells in a double-transgenic model
    • Fulcher DA, Basten A. 1994. Reduced life span of anergic self-reactive B cells in a double-transgenic model. J. Exp. Med. 179:125-34
    • (1994) J. Exp. Med. , vol.179 , pp. 125-134
    • Fulcher, D.A.1    Basten, A.2
  • 140
    • 0026443849 scopus 로고
    • Adaptive cellular interactions in the immune system: The tunable activation threshold and the significance of subthreshold responses
    • Grossman Z, Paul WE. 1992. Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses. Proc. Natl. Acad. Sci. USA 89:10365-69
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10365-10369
    • Grossman, Z.1    Paul, W.E.2
  • 141
    • 0025231503 scopus 로고
    • Developmental biology of T cells in T-cell receptor transgenic mice
    • von Boehmer H. 1990. Developmental biology of T cells in T-cell receptor transgenic mice. Annu. Rev. Immunol. 8:531-56
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 531-556
    • Von Boehmer, H.1
  • 144
    • 0025933951 scopus 로고
    • Kinetics and efficiency of positive selection in the thymus of normal and T cell receptor transgenic mice
    • Huesmann M, Scott B, Kisielow P, von Boehmer H. 1991. Kinetics and efficiency of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 66:533
    • (1991) Cell , vol.66 , pp. 533
    • Huesmann, M.1    Scott, B.2    Kisielow, P.3    Von Boehmer, H.4
  • 145
    • 0029807629 scopus 로고    scopus 로고
    • B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen
    • Lang J, Jackson M, Teyton L, Brunmark A, Kane K, Nemazee D. 1996. B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen. J. Exp. Med. 184:1685-97
    • (1996) J. Exp. Med. , vol.184 , pp. 1685-1697
    • Lang, J.1    Jackson, M.2    Teyton, L.3    Brunmark, A.4    Kane, K.5    Nemazee, D.6
  • 146
  • 147
    • 0025908321 scopus 로고
    • Peripheral selection of the T cell repertoire
    • Rocha B, von Boehmer H. 1991. Peripheral selection of the T cell repertoire. Science 251:1225-28
    • (1991) Science , vol.251 , pp. 1225-1228
    • Rocha, B.1    Von Boehmer, H.2
  • 149
    • 0033548496 scopus 로고    scopus 로고
    • Linear differentiation of cytotoxic effectors into memory T lymphocytes
    • Opferman JT, Ober BT, Ashton-Rickardt PG. 1999. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science 283:1742-45
    • (1999) Science , vol.283 , pp. 1742-1745
    • Opferman, J.T.1    Ober, B.T.2    Ashton-Rickardt, P.G.3
  • 150
    • 0030037519 scopus 로고    scopus 로고
    • B cell differentiation and isotype switching is related to division cycle number
    • Hodgkin PD, Lee JH, Lyons AB. 1996. B cell differentiation and isotype switching is related to division cycle number. J. Exp. Med. 184:277-81
    • (1996) J. Exp. Med. , vol.184 , pp. 277-281
    • Hodgkin, P.D.1    Lee, J.H.2    Lyons, A.B.3
  • 152
    • 0016339641 scopus 로고
    • The immune system: A web of V-domains
    • Jerne NK. 1974. The immune system: a web of V-domains. Harvey Lect. 70:93-110
    • (1974) Harvey Lect. , vol.70 , pp. 93-110
    • Jerne, N.K.1
  • 153
    • 0021285401 scopus 로고
    • From an antigencentered, clonal perspective of immune responses to an organism-centered, network perspective of autonomous activity in a self-referential immune system
    • Coutinho A, Forni L, Holmberg D, Ivars F, Vaz N. 1984. From an antigencentered, clonal perspective of immune responses to an organism-centered, network perspective of autonomous activity in a self-referential immune system. Immunol. Rev. 79:151-68
    • (1984) Immunol. Rev. , vol.79 , pp. 151-168
    • Coutinho, A.1    Forni, L.2    Holmberg, D.3    Ivars, F.4    Vaz, N.5
  • 154
    • 0018097280 scopus 로고
    • Self and nonsense: An organism-centered approach to immunology
    • Vaz NM, Varela FJ. 1978. Self and nonsense: an organism-centered approach to immunology. Med. Hypotheses 4:231-67
    • (1978) Med. Hypotheses , vol.4 , pp. 231-267
    • Vaz, N.M.1    Varela, F.J.2
  • 155
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. 1994. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12:991-1045
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 156
    • 0014941813 scopus 로고
    • A theory of self-nonself discrimination
    • Bretscher P, Cohn M. 1970. A theory of self-nonself discrimination. Science 169:1042-49
    • (1970) Science , vol.169 , pp. 1042-1049
    • Bretscher, P.1    Cohn, M.2
  • 157
    • 0028364453 scopus 로고
    • Involvement of human muscle acetylcholine receptor alphasubunit gene (CHRNA) in susceptibility to myasthenia gravis
    • Garchon HJ, Djabiri F, Viard JP, Gajdos P, Bach JF. 1994. Involvement of human muscle acetylcholine receptor alphasubunit gene (CHRNA) in susceptibility to myasthenia gravis. Proc. Natl. Acad. Sci. USA 91:4668-72
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4668-4672
    • Garchon, H.J.1    Djabiri, F.2    Viard, J.P.3    Gajdos, P.4    Bach, J.F.5
  • 158
    • 0018567632 scopus 로고
    • Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination
    • Perelson AS, Oster GF. 1979. Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-non-self discrimination. J. Theor. Biol. 81:645-70
    • (1979) J. Theor. Biol. , vol.81 , pp. 645-670
    • Perelson, A.S.1    Oster, G.F.2
  • 161
    • 0032507958 scopus 로고    scopus 로고
    • Evolution of indirect reciprocity by image scoring
    • Nowak MA, Sigmund K. 1998. Evolution of indirect reciprocity by image scoring. Nature 393:573-77
    • (1998) Nature , vol.393 , pp. 573-577
    • Nowak, M.A.1    Sigmund, K.2
  • 162
    • 0033119814 scopus 로고    scopus 로고
    • Prisoner's dilemma in an RNA virus
    • Turner PE, Chao L. 1999. Prisoner's dilemma in an RNA virus. Nature 398:441-43
    • (1999) Nature , vol.398 , pp. 441-443
    • Turner, P.E.1    Chao, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.