-
1
-
-
0033581935
-
Selecting and maintaining a diverse T-cell repertoire
-
Goldrath, A.W., and M.J. Bevan. 1999. Selecting and maintaining a diverse T-cell repertoire. Nature. 402:255-262.
-
(1999)
Nature
, vol.402
, pp. 255-262
-
-
Goldrath, A.W.1
Bevan, M.J.2
-
3
-
-
0027491232
-
Control points in early T-cell development
-
Godfrey, D.I., and A. Zlotnik. 1993. Control points in early T-cell development. Immunol. Today. 14:547-553.
-
(1993)
Immunol. Today.
, vol.14
, pp. 547-553
-
-
Godfrey, D.I.1
Zlotnik, A.2
-
5
-
-
0027972407
-
The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult alpha beta thymocytes
-
Andjelic, S., J. Drappa, E. Lacy, K.B. Elkon, and J. Nikolic-Zugic. 1994. The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult alpha beta thymocytes. Int. Immunol. 6:73-79.
-
(1994)
Int. Immunol.
, vol.6
, pp. 73-79
-
-
Andjelic, S.1
Drappa, J.2
Lacy, E.3
Elkon, K.B.4
Nikolic-Zugic, J.5
-
6
-
-
0029036650
-
Expression and function of mouse Fas antigen on immature and mature T cells
-
Nishimura, Y., A. Ishii, Y. Kobayashi, Y. Yamasaki, and S. Yonehara. 1995. Expression and function of mouse Fas antigen on immature and mature T cells. J. Immunol. 154:4395-4403.
-
(1995)
J. Immunol.
, vol.154
, pp. 4395-4403
-
-
Nishimura, Y.1
Ishii, A.2
Kobayashi, Y.3
Yamasaki, Y.4
Yonehara, S.5
-
7
-
-
0027490727
-
The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr
-
Drappa, J., N. Brot, and K.B. Elkon. 1993. The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr. Proc. Natl. Acad. Sci. USA. 90:10340-10344.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10340-10344
-
-
Drappa, J.1
Brot, N.2
Elkon, K.B.3
-
8
-
-
0031227818
-
Fas ligand expression is restricted to nonlymphoid thymic components in situ
-
French, L.E., A. Wilson, M. Hahne, I. Viard, J. Tschopp, and H.R. MacDonald. 1997. Fas ligand expression is restricted to nonlymphoid thymic components in situ. J. Immunol. 159:2196-2202.
-
(1997)
J. Immunol.
, vol.159
, pp. 2196-2202
-
-
French, L.E.1
Wilson, A.2
Hahne, M.3
Viard, I.4
Tschopp, J.5
MacDonald, H.R.6
-
9
-
-
0042161809
-
Mutation in Fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptors
-
Boursalian, T.E., and P.J. Fink. 2003. Mutation in Fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptors. J. Exp. Med. 198:349-360.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 349-360
-
-
Boursalian, T.E.1
Fink, P.J.2
-
10
-
-
0032482160
-
A role for Fas in negative selection of thymocytes in vivo
-
Kishimoto, H., C.D. Surh, and J. Sprent. 1998. A role for Fas in negative selection of thymocytes in vivo. J. Exp. Med. 187:1427-1438.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1427-1438
-
-
Kishimoto, H.1
Surh, C.D.2
Sprent, J.3
-
11
-
-
0030497507
-
Fas modulation of apoptosis during negative selection of thymocytes
-
Castro, J.E., J.A. Listman, B.A. Jacobson, Y. Wang, P.A. Lopez, S. Ju, P.W. Finn, and D.L. Perkins. 1996. Fas modulation of apoptosis during negative selection of thymocytes. Immunity. 5:617-627.
-
(1996)
Immunity
, vol.5
, pp. 617-627
-
-
Castro, J.E.1
Listman, J.A.2
Jacobson, B.A.3
Wang, Y.4
Lopez, P.A.5
Ju, S.6
Finn, P.W.7
Perkins, D.L.8
-
12
-
-
0028980902
-
Fas and Fas ligand: Lpr and gld mutations
-
Nagata, S., and T. Suda. 1995. Fas and Fas ligand: lpr and gld mutations. Immunol. Today. 16:39-43.
-
(1995)
Immunol. Today.
, vol.16
, pp. 39-43
-
-
Nagata, S.1
Suda, T.2
-
13
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler, M., M. Thome, M. Hahne, P. Schneider, K. Hofmann, V. Steiner, J.L. Bodmer, M. Schroter, K. Burns, C. Mattmann, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature. 388:190-195.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.L.7
Schroter, M.8
Burns, K.9
Mattmann, C.10
-
14
-
-
0030746740
-
Casper is a FADD-and caspase-related inducer of apoptosis
-
Shu, H.B., D.R. Halpin, and D.V. Goeddel. 1997. Casper is a FADDand caspase-related inducer of apoptosis. Immunity. 6:751-763.
-
(1997)
Immunity
, vol.6
, pp. 751-763
-
-
Shu, H.B.1
Halpin, D.R.2
Goeddel, D.V.3
-
15
-
-
0030841911
-
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- And CD-95-induced apoptosis
-
Hu, S., C. Vincenz, J. Ni, R. Gentz, and V.M. Dixit. 1997. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J. Biol. Chem. 272:17255-17257.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17255-17257
-
-
Hu, S.1
Vincenz, C.2
Ni, J.3
Gentz, R.4
Dixit, V.M.5
-
16
-
-
0030877440
-
CASH, a novel caspase homologue with death effector domains
-
Goltsev, Y.V., A.V. Kovalenko, E. Arnold, E.E. Varfolomeev, V.M. Brodianskii, and D. Wallach. 1997. CASH, a novel caspase homologue with death effector domains. J. Biol. Chem. 272:19641-19644.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19641-19644
-
-
Goltsev, Y.V.1
Kovalenko, A.V.2
Arnold, E.3
Varfolomeev, E.E.4
Brodianskii, V.M.5
Wallach, D.6
-
17
-
-
0030810981
-
FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis
-
Srinivasula, S.M., M. Ahmad, S. Ottilie, F. Bullrich, S. Banks, Y. Wang, T. Fernandes-Alnemri, C.M. Croce, G. Litwack, K.J. Tomaselli, et al. 1997. FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J. Biol. Chem. 272:18542-18545.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18542-18545
-
-
Srinivasula, S.M.1
Ahmad, M.2
Ottilie, S.3
Bullrich, F.4
Banks, S.5
Wang, Y.6
Fernandes-Alnemri, T.7
Croce, C.M.8
Litwack, G.9
Tomaselli, K.J.10
-
18
-
-
0030758315
-
MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death
-
Han, D.K., P.M. Chaudhary, M.E. Wright, C. Friedman, B.J. Trask, R.T. Riedel, D.G. Baskin, S.M. Schwartz, and L. Hood. 1997. MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc. Natl. Acad. Sci. USA. 94:11333-11338.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11333-11338
-
-
Han, D.K.1
Chaudhary, P.M.2
Wright, M.E.3
Friedman, C.4
Trask, B.J.5
Riedel, R.T.6
Baskin, D.G.7
Schwartz, S.M.8
Hood, L.9
-
19
-
-
0030961084
-
CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis
-
Inohara, N., T. Koseki, Y. Hu, S. Chen, and G. Nunez. 1997. CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis. Proc. Natl. Acad. Sci. USA. 94:10717-10722.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10717-10722
-
-
Inohara, N.1
Koseki, T.2
Hu, Y.3
Chen, S.4
Nunez, G.5
-
20
-
-
7344220967
-
Cell death attenuation by "Usurpin", a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
-
Rasper, D.M., J.P. Vaillancourt, S. Hadano, V.M. Houtzager, I. Seiden, S.L. Keen, P. Tawa, S. Xanthoudakis, J. Nasir, D. Martindale, et al. 1998. Cell death attenuation by "Usurpin", a mammalian DEDcaspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ. 5:271-288.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 271-288
-
-
Rasper, D.M.1
Vaillancourt, J.P.2
Hadano, S.3
Houtzager, V.M.4
Seiden, I.5
Keen, S.L.6
Tawa, P.7
Xanthoudakis, S.8
Nasir, J.9
Martindale, D.10
-
21
-
-
0035496099
-
Regulation of lymphocyte proliferation and death by FLIP
-
Thome, M., and J. Tschopp. 2001. Regulation of lymphocyte proliferation and death by FLIP. Nat. Rev. Immunol. 1:50-58.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 50-58
-
-
Thome, M.1
Tschopp, J.2
-
22
-
-
0037099678
-
c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
-
Chang, D.W., Z. Xing, Y. Pan, A. Algeciras-Schimnich, B.C. Barnhart, S. Yaish-Ohad, M.E. Peter, and X. Yang. 2002. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J. 21:3704-3714.
-
(2002)
EMBO J.
, vol.21
, pp. 3704-3714
-
-
Chang, D.W.1
Xing, Z.2
Pan, Y.3
Algeciras-Schimnich, A.4
Barnhart, B.C.5
Yaish-Ohad, S.6
Peter, M.E.7
Yang, X.8
-
23
-
-
0036179645
-
Death receptors couple to both cell proliferation and apoptosis
-
Budd, R.C. 2002. Death receptors couple to both cell proliferation and apoptosis. J. Clin. Invest. 109:437-441.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 437-441
-
-
Budd, R.C.1
-
24
-
-
0036310708
-
The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes
-
Lens, S.M., T. Kataoka, K.A. Fortner, A. Tinel, I. Ferrero, R.H. MacDonald, M. Hahne, F. Beermann, A. Attinger, H.A. Orbea, et al. 2002. The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes. Mol. Cell. Biol. 22:5419-5433.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5419-5433
-
-
Lens, S.M.1
Kataoka, T.2
Fortner, K.A.3
Tinel, A.4
Ferrero, I.5
MacDonald, R.H.6
Hahne, M.7
Beermann, F.8
Attinger, A.9
Orbea, H.A.10
-
25
-
-
18744425429
-
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
-
Kataoka, T., R.C. Budd, N. Holler, M. Thome, F. Martinon, M. Irmler, K. Burns, M. Hahne, N. Kennedy, M. Kovacsovics, and J. Tschopp. 2000. The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr. Biol. 10:640-648.
-
(2000)
Curr. Biol.
, vol.10
, pp. 640-648
-
-
Kataoka, T.1
Budd, R.C.2
Holler, N.3
Thome, M.4
Martinon, F.5
Irmler, M.6
Burns, K.7
Hahne, M.8
Kennedy, N.9
Kovacsovics, M.10
Tschopp, J.11
-
26
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh, W.C., A. Itie, A.J. Elia, M. Ng, H.B. Shu, A. Wakeham, C. Mirtsos, N. Suzuki, M. Bonnard, D.V. Goeddel, and T.W. Mak. 2000. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity. 12:633-642.
-
(2000)
Immunity
, vol.12
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
Ng, M.4
Shu, H.B.5
Wakeham, A.6
Mirtsos, C.7
Suzuki, N.8
Bonnard, M.9
Goeddel, D.V.10
Mak, T.W.11
-
27
-
-
0030293636
-
Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation
-
Lucas, B., and R.N. Germain. 1996. Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation. Immunity. 5:461-477.
-
(1996)
Immunity
, vol.5
, pp. 461-477
-
-
Lucas, B.1
Germain, R.N.2
-
28
-
-
0029556979
-
T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl- transferase gene by site-directed recombination
-
Hennet, T., F.K. Hagen, L.A. Tabak, and J.D. Marth. 1995. T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination. Proc. Natl. Acad. Sci. USA. 92:12070-12074.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12070-12074
-
-
Hennet, T.1
Hagen, F.K.2
Tabak, L.A.3
Marth, J.D.4
-
29
-
-
23744487497
-
Cellular FLICE-inhibitory protein (cFLIP) is required for T cell survival and cycling
-
Chau, H., V. Wong, N.-J. Chen, H.-L. Huang, W.-J. Lin, C. Mirtsos, A. Elford, M. Bonnard, A. Wakeham, A.I. You-Ten, et al. 2005. Cellular FLICE-inhibitory protein (cFLIP) is required for T cell survival and cycling. J. Exp. Med. 202:405-413.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 405-413
-
-
Chau, H.1
Wong, V.2
Chen, N.-J.3
Huang, H.-L.4
Lin, W.-J.5
Mirtsos, C.6
Elford, A.7
Bonnard, M.8
Wakeham, A.9
You-Ten, A.I.10
-
30
-
-
0031570932
-
Increased lymphocyte apoptosis in Fas ligand transgenic mice
-
Cheng, J., C. Liu, P. Yang, T. Zhou, and J.D. Mountz. 1997. Increased lymphocyte apoptosis in Fas ligand transgenic mice. J. Immunol. 159:674-684.
-
(1997)
J. Immunol.
, vol.159
, pp. 674-684
-
-
Cheng, J.1
Liu, C.2
Yang, P.3
Zhou, T.4
Mountz, J.D.5
-
31
-
-
1642433102
-
c-FLICE inhibitory protein expression inhibits T-cell activation
-
Tai, T.S., L.W. Fang, and M.Z. Lai. 2004. c-FLICE inhibitory protein expression inhibits T-cell activation. Cell Death Differ. 11:69-79.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 69-79
-
-
Tai, T.S.1
Fang, L.W.2
Lai, M.Z.3
-
32
-
-
1842477263
-
Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation
-
Wu, W., L. Rinaldi, K.A. Fortner, J.Q. Russell, J. Tschopp, C. Irvin, and R.C. Budd. 2004. Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation. J. Immunol. 172:4724-4732.
-
(2004)
J. Immunol.
, vol.172
, pp. 4724-4732
-
-
Wu, W.1
Rinaldi, L.2
Fortner, K.A.3
Russell, J.Q.4
Tschopp, J.5
Irvin, C.6
Budd, R.C.7
-
33
-
-
9144269945
-
Cellular FLIP (long isoform) overexpression in T cells drives Th2 effector responses and promotes immunoregulation in experimental autoimmune encephalomyelitis
-
Tseveleki, V., J. Bauer, E. Taoufik, C. Ruan, L. Leondiadis, S. Haralambous, H. Lassmann, and L. Probert. 2004. Cellular FLIP (long isoform) overexpression in T cells drives Th2 effector responses and promotes immunoregulation in experimental autoimmune encephalomyelitis. J. Immunol. 173:6619-6626.
-
(2004)
J. Immunol.
, vol.173
, pp. 6619-6626
-
-
Tseveleki, V.1
Bauer, J.2
Taoufik, E.3
Ruan, C.4
Leondiadis, L.5
Haralambous, S.6
Lassmann, H.7
Probert, L.8
-
34
-
-
0033426959
-
Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes
-
Van Parijs, L., Y. Refaeli, A.K. Abbas, and D. Baltimore. 1999. Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes. Immunity. 11:763-770.
-
(1999)
Immunity
, vol.11
, pp. 763-770
-
-
Van Parijs, L.1
Refaeli, Y.2
Abbas, A.K.3
Baltimore, D.4
-
35
-
-
0038373452
-
cFLIP-L inhibits p38 MAPK activation: An additional anti-apoptotic mechanism in bile acid-mediated apoptosis
-
Grambihler, A., H. Higuchi, S.F. Bronk, and G.J. Gores. 2003. cFLIP-L inhibits p38 MAPK activation: an additional anti-apoptotic mechanism in bile acid-mediated apoptosis. J. Biol. Chem. 278:26831-26837.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26831-26837
-
-
Grambihler, A.1
Higuchi, H.2
Bronk, S.F.3
Gores, G.J.4
-
36
-
-
4644286871
-
FLICE-like inhibitory protein (FLIP) protects against apoptosis and suppresses NF-kappaB activation induced by bacterial lipopolysaccharide
-
Bannerman, D.D., K.T. Eiting, R.K. Winn, and J.M. Harlan. 2004. FLICE-like inhibitory protein (FLIP) protects against apoptosis and suppresses NF-kappaB activation induced by bacterial lipopolysaccharide. Am. J. Pathol. 165:1423-1431. '
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 1423-1431
-
-
Bannerman, D.D.1
Eiting, K.T.2
Winn, R.K.3
Harlan, J.M.4
-
37
-
-
3543096349
-
NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP
-
Kreuz, S., D. Siegmund, J.J. Rumpf, D. Samel, M. Leverkus, O. Janssen, G. Hacker, O. Dittrich-Breiholz, M. Kracht, P. Scheurich, and H. Wajant. 2004. NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP. J. Cell Biol. 166:369-380.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 369-380
-
-
Kreuz, S.1
Siegmund, D.2
Rumpf, J.J.3
Samel, D.4
Leverkus, M.5
Janssen, O.6
Hacker, G.7
Dittrich-Breiholz, O.8
Kracht, M.9
Scheurich, P.10
Wajant, H.11
-
38
-
-
0037380628
-
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
-
Salmena, L., B. Lemmers, A. Hakem, E. Matysiak-Zablocki, K. Murakami, P.Y. Au, D.M. Berry, L. Tamblyn, A. Shehabeldin, E. Migon, et al. 2003. Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes Dev. 17:883-895.
-
(2003)
Genes Dev.
, vol.17
, pp. 883-895
-
-
Salmena, L.1
Lemmers, B.2
Hakem, A.3
Matysiak-Zablocki, E.4
Murakami, K.5
Au, P.Y.6
Berry, D.M.7
Tamblyn, L.8
Shehabeldin, A.9
Migon, E.10
-
39
-
-
0029917507
-
Fibroblast growth factor receptor 3 is a negative regulator of bone growth
-
Deng, C., A. Wynshaw-Boris, F. Zhou, A. Kuo, and P. Leder. 1996. Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell. 84:911-921.
-
(1996)
Cell.
, vol.84
, pp. 911-921
-
-
Deng, C.1
Wynshaw-Boris, A.2
Zhou, F.3
Kuo, A.4
Leder, P.5
-
40
-
-
0034487368
-
Widespread recombinase expression using FLPeR (flipper) mice
-
Farley, F.W., P. Soriano, L.S. Steffen, and S.M. Dymecki. 2000. Widespread recombinase expression using FLPeR (flipper) mice. Genesis. 28:106-110.
-
(2000)
Genesis
, vol.28
, pp. 106-110
-
-
Farley, F.W.1
Soriano, P.2
Steffen, L.S.3
Dymecki, S.M.4
-
41
-
-
0035999828
-
Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes
-
Guo, J., A. Hawwari, H. Li, Z. Sun, S.K. Mahanta, D.R. Littman, M.S. Krangel, and Y.W. He. 2002. Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. Nat. Immunol. 3:469-476.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 469-476
-
-
Guo, J.1
Hawwari, A.2
Li, H.3
Sun, Z.4
Mahanta, S.K.5
Littman, D.R.6
Krangel, M.S.7
He, Y.W.8
|